Clinical trials: Perimenopausal Disorder, open to volunteers
Perimenopause, Menopause
The Effects of Resistance Training and a Plant-Based Supplement on Perimenopausal Symptoms and Muscle Health.
The aim of this clinical trial is to determine if resistance training and a newly developed plant-based nutritional supplement can improve the symptoms and musculoskeletal health of perimenopausal women.
- Trial name
- NCT07135232
- Testing
- Sarmentosin - L- theanine, Resistance Training
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Iron Deficiency Anemia Treatment, Iron Deficiency
How Does Perimenopausal Menorrhagia Affect Women's Quality of Life and Cognitive Function?
The goal of this clinical trial is to investigate how iron status and heavy bleeding during the menopausal transition affect women's cognitive function and quality of life.
- Conditions
- Iron Deficiency Anemia Treatment, Iron Deficiency, Iron Deficiency (Without Anemia)
- Trial name
- MENO (NCT06798584)
- Testing
- FeoSol Original Iron Supplement Tablets, 21st Century Gelatin Capsules
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Purdue University
Osteopenia, Osteoporosis
Calcium-Rich Food Versus Calcium Carbonate for Bone Health
This study will compare adherence, tolerability, safety, and treatment satisfaction between a calcium-rich food and a traditional calcium carbonate supplement in women ages 40 to 90 who are at increased risk for osteoporosis.
- Conditions
- Osteopenia, Osteoporosis, Bone Health in Perimenopausal Women, Menopause Related Conditions
- Trial name
- NCT07763509
- Testing
- 500 mg calcium from milk-derived minerals, Calcium Carbonate 500 MG
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Cornell University
Infertility, Female, Perimenopausal Disorder
Autologous Platelet Rich Plasma (PRP) Intra Ovarian Infusion in Perimenopausal Women
Autologous PRP intra ovarian infusion may improve ovarian response and women's hormonal profile and may promote folliculogenesis in perimenopausal women.
- Conditions
- Infertility, Female, Perimenopausal Disorder, Menstrual Cycle Abnormal
- Trial name
- PRP (NCT03951194)
- Testing
- Autologous Platelet Rich Plasma (PRP) intra ovarian infusion
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genesis Athens Clinic
Healthly Volunteers, Oncologic Disease
A Two-Way Path to Health: Environmental Influences on Skeletal Muscle Endocrine Function
Given the well-established anti-inflammatory and health-promoting effects of physical activity as a non-pharmacological intervention, an important question remains whether different types of exercise differ in their ability to…
- Trial name
- COMPASS (NCT07706465)
- Testing
- Experimental: IWT- Interval Walking Training, Exercise training II, Walking
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Quality of Life, Depression
Effects of Jin Shin Jyutsu-Based Hand Application on Quality of Life and Psychosocial Status in Perimenopausal Women
This study aims to evaluate the effect of Jin Shin Jyutsu-based hand application guided by the Transactional Model of Stress and Coping on quality of life and psychosocial status in perimenopausal women.
- Conditions
- Quality of Life, Depression, Anxiety, Stress
- Trial name
- NCT07376395
- Testing
- General Health Education, Jin Shin Jyutsu®-Based Hand Application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Menopause, Perimenopausal Disorder
Virtual perI-/Menopause Registry of AusTrALia
13 million (50.7%) Australians are born with ovaries, 14% (~3 million) are currently aged 40-59 yrs, \& all such who live to midlife will experience menopause, defined as >12 months without a period.
- Conditions
- Menopause, Perimenopausal Disorder, Postmenopausal Symptoms, Health Knowledge, Attitudes, Practice
- Trial name
- VITAL (NCT06487130)
- Testing
- N/A Observational Registry
- Where
- Australia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Bespoke Clinical Research
Menopausal Women
The Effect of Value Clarification Based on Meleis's Transition Theory on Menopausal Symptoms, Depression, Anxiety, Stress, and Quality of Life in Perimenopausal Women
Menopause is a life stage influenced not only by hormonal factors but also by psychological, social, and cultural factors. Symptoms such as hot flashes, sleep problems, and mood changes may occur, and their severity depends on…
- Trial name
- NCT07584109
- Testing
- value clarification, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Ordu University
Sarcopenia, Physical Inactivity
Women in Action: A Multicomponent Intervention for Older Women
"Women in Action" is a quasi-experimental, mixed-methods study evaluating a 16-week multicomponent intervention (supervised strength/aerobic/balance training plus psychoeducational and nutrition-focused behavioral workshops) for…
- Conditions
- Sarcopenia, Physical Inactivity, Menopause, Healthy Aging
- Trial name
- WIA (NCT07860424)
- Testing
- Multicomponent exercise, nutrition, and psychoeducational program
- Where
- 2 sites in Spain
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Universidad de Oviedo
Perimenopausal Bone Loss
Prunes Preventing Bone Loss in Perimenopause
Dietary interventions of prune consumption during the transmenopausal period are innovative methods to prevent bone loss. Modern medicine does not intervene to prevent or attenuate this highly vulnerable period of bone loss…
- Trial name
- Prune-UP (NCT07120997)
- Testing
- Prunes, Calcium supplement, Vitamin D Supplement
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Penn State University
Climacteric Syndrome, Postmenopausal Symptoms
Multimodal Program for Climacteric Women
Your study seems to aim at emphasizing the significance of non-pharmacological and non-hormonal approaches in managing menopausal symptoms, particularly focusing on muscle training and education.
- Conditions
- Climacteric Syndrome, Postmenopausal Symptoms, Menopause, Perimenopausal Disorder
- Trial name
- NCT06419972
- Testing
- multimodal physiotherapy programme
- Where
- 2 sites in Spain
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Post-menopause, Pre-menopause
VEDA Study (DHEA vs Estradiol)
This study is being done to compare two vaginal treatments, vaginal estrogen and vaginal DHEA, that are used to treat vaginal and urinary symptoms related to menopause.
- Conditions
- Post-menopause, Pre-menopause, Sexual Function, Menopause
- Trial name
- NCT07574216
- Testing
- DHEA ovals, Estradiol 0.01% Vag Cream
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Arthralgia, Menopause
The MUSE Study for Menopausal Arthralgia
The investigators plan to conduct a pilot 4-arm, randomized study comprising the following interventions: muscle strengthening exercises (MSE) alone, estrogen therapy (ET) alone, and a combination of MSE and ET, compared to usual…
- Conditions
- Arthralgia, Menopause, Perimenopausal Disorder, Joint Pain
- Trial name
- MUSE (NCT06530459)
- Testing
- Menopausal hormone therapy, Exercise training, Menopausal hormone therapy + exercise training
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Overweight and/or Obesity, Perimenopausal Women
Effects of a 6-months Fiber- and Polyphenol-rich Diet on Brain Inflammatory Processes in Perimenopausal Women Living With Overweight or Obesity
People living with obesity have a higher risk of late-life cognitive decline and developing dementia. In women, the risk of cognitive decline may further raise during the menopausal transition, a period of substantial hormonal…
- Trial name
- INFLAME (NCT07501377)
- Testing
- Polybiotic dietary intervention
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Max Planck Institute for Human Cognitive and Brain Sciences
Cardiovascular Outcome, Overweight and Obese Women
Impact of Lean Pork on Endothelial Function in Perimenopause
The goal of this study is to examine the impact of a diet high in fresh lean pork, compared to a plant-based diet, on cardiovascular function and vasomotor symptoms in perimenopausal women with overweight and obesity.
- Conditions
- Cardiovascular Outcome, Overweight and Obese Women, Perimenopausal Women, Vasomotor Symptoms (VMS)
- Trial name
- LEAP (NCT06976112)
- Testing
- Pork Diet, Plant Diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Late-perimenopause, Menopause
Time-Restricted Eating in Combination With a Low Glycaemic Index Diet on Cognitive Function, Biological Ageing and Metabolic Health in Perimenopause and Menopause.
The goal of this randomised controlled trial is to investigate whether Time-Restricted Eating (TRE) combined with a Low Glycaemic Index Mediterranean Diet can improve cognitive function, metabolic health, and biological ageing in…
- Conditions
- Late-perimenopause, Menopause, Perimenopause
- Trial name
- NutriAge (NCT07378787)
- Testing
- Time-Restricted Low-Glycaemic Index Diet
- Where
- 2 sites in Croatia, Cyprus
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Nicosia
Insomnia, Menopause
No More Sleepless Nights in Perimenopause
The goal of the clinical trial is to learn if Hormone Replacement Therapy (HRT) and Cognitive Behavioral Therapy (CBT-I) can treat insomnia in menopausal women.
- Trial name
- NCT06497894
- Testing
- Cognitive Behavioural Therapy for Insomnia (CBT-I), Hormone Replacement Therapy (HRT), Sleep Hygiene
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Healthy, Perimenopausal Depression
Multidimensional Determinants of Functional Health In Women Aged 45-60
The goal of this observational study is to learn about the multidimensional determinants of functional health in women aged 45 to 60 years.
- Conditions
- Healthy, Perimenopausal Depression, Menopausal Complaints, Bone Mineral Density
- Trial name
- NCT07667699
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kartal City Hospital