Clinical trials: Perimenopause, open to volunteers
Perimenopause
Occupational Disruption and Role Strain During Perimenopause
The purpose of this sequential exploratory mixed-methods study is to examine the relationship between perimenopausal symptom severity and occupational performance, occupational balance, and role participation in women aged 40-55.
- Trial name
- NCT07570732
- Testing
- Confidential Surveys
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Russell Sage College
Menopause, Perimenopause
Hormone thERapy Effects on BRAin-HEART Health During the Menopausal Transition
The goal of this clinical trial is to learn whether it is feasible to conduct a larger study comparing transdermal menopausal hormone therapy (MHT) versus no hormone therapy in menopausal women with vasomotor symptoms (hot…
- Conditions
- Menopause, Perimenopause, Vasomotor Symptoms, Cardiovascular Disease Risk Factor
- Trial name
- HERBRAVEHEART (NCT07732452)
- Testing
- Transdermal estradiol, Standard of care - non hormonal
- Volunteers
- 100 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Menopausal Complaints, Vaginal Atrophy
Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living With HIV
This is a research study about the effects of vaginal estradiol compared to moisturizer on vaginal symptoms of menopause and the microbiome in women with HIV.
- Conditions
- Menopausal Complaints, Vaginal Atrophy, Genitourinary Symptoms, HIV (Human Immunodeficiency Virus)
- Trial name
- NCT07526948
- Testing
- Vaginal estradiol tablets, Vaginal moisturizer
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Perimenopause, Perimenopausal Depression
A Trial to Investigate the Accuracy of a Wearable Device in Collecting Data Related to Perimenopausal Symptoms in Women
The goal of this observational study is to investigate the accuracy of the device in characterizing perimenopausal and menopausal symptoms including vasomotor symptoms, anxiety, sleep quality compared to self-reported symptoms…
- Conditions
- Perimenopause, Perimenopausal Depression, Perimenopausal Insomnia, Perimenopausal Women
- Trial name
- NCT07022925
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- IdentifyHer Limited
Perimenopause, Menopause
Evaluation of the Effects of Lifestyle Medicine and Mindfulness-based Group Medical Visits on Stress, Microbiome, and Quality of Life in Women Experiencing Perimenopause and Menopause
While perimenopause and menopause are natural biological transitions, women may experience a wide range of physical, emotional, and cognitive symptoms.
- Trial name
- NCT07619352
- Testing
- Navigating Menopause with a Mindfulness-Based Group Medical Visit
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ohio State University
Perimenopause, PMDD
Transcutaneous Auricular Neurostimulation (tAN) for Premenstrual Dysphoric Disorder (PMDD) and Perimenopause
Transcutaneous Auricular Neurostimulation (tAN) will be administered to women with premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), and perimenopause.
- Trial name
- NCT07688720
- Testing
- transcutaneous auricular neurostimulation (tAN)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Texas Christian University
Perimenopause, Subjective Cognitive Complaints
Exercise in Perimenopause to Improve Cognitive Health
Perimenopause is now considered a possible risk factor for dementia and may contribute to the fact that 2/3 of those living with Alzheimer's disease are females.
- Trial name
- EPIC (NCT07272174)
- Testing
- Progressive Resistance Training, Balance, Flexibility, and Tone Exercises
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Women
Feasibility of Different Types of Exercise Training in Perimenopausal Females
Throughout the menopause transition, women experience many symptoms (i.e., hot flashes, night sweats) that can significantly reduce their quality of life. Moreover, their risk of heart disease increases substantially.
- Trial name
- POWER (NCT07132385)
- Testing
- Guidelines-based moderate-intensity continuous exercise, High-intensity interval training, Stretching exercise
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Toronto
Quality of Life, Depression
Effects of Jin Shin Jyutsu-Based Hand Application on Quality of Life and Psychosocial Status in Perimenopausal Women
This study aims to evaluate the effect of Jin Shin Jyutsu-based hand application guided by the Transactional Model of Stress and Coping on quality of life and psychosocial status in perimenopausal women.
- Conditions
- Quality of Life, Depression, Anxiety, Stress
- Trial name
- NCT07376395
- Testing
- General Health Education, Jin Shin Jyutsu®-Based Hand Application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Menopause
Menopause Transition, Sex Hormone Deficiency and Autonomic and Vascular Function
This is a longitudinal study to determine the influence of the menopause transition on autonomic and vascular function. PI Keller-Ross has published data demonstrating that postmenopausal females have greater sympathetic neural…
- Trial name
- NCT06490146
- Testing
- No intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Mental Health, Perimenopause
Impact of Intermittent Fasting on the Mental Health of Perimenopausal Women
This study will explore how intermittent fasting (specifically the 16/8 method) affects the mental health of women who are in the perimenopause stage.
- Conditions
- Mental Health, Perimenopause, Intermittent Fasting
- Trial name
- NCT07481513
- Testing
- Intermittent fasting (16/8)
- Where
- Lebanon
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Migraine, Menopausal
Migraine Menopause Study
This study will assess whether the migraine medication eptinezumab (Vyepti) reduces migraine days in women who are in perimenopause and early menopause and who also experience night sweats and hot flashes.
- Conditions
- Migraine, Menopausal, Perimenopause
- Trial name
- NCT07916571
- Testing
- Eptinezumab 100 mg or Eptinezumab 300 mg administered intravenously in 100 mL saline solution
- Volunteers
- 120 people
- Sponsor
- Alberta Neurologic Centre
Perimenopause
Hemodynamics After Resistance Training
Women's blood vessel health gets worse after menopause, or "the change of life". Some women exercise less during menopause. Exercise can improve blood vessel health.
- Trial name
- HeART (NCT07022340)
- Testing
- Resistance Training Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Adhesive Capsulitis of the Shoulder, Frozen Shoulder
Frozen Shoulder and Hormone Replacement Therapy
The purpose of this study is to determine the effects of hormone replacement therapy (HRT) in addition to standard treatment on frozen shoulder symptoms in women with age-related changes to their menstrual cycle.
- Trial name
- FSHRT (NCT07278323)
- Testing
- Hormone Replacement Therapy (HRT), Corticosteroid and 1%lidocain, physical therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Perimenopause, Perimenopause-Related Depression
Impact of a Novel Functional Snack on Perimenopausal Symptoms and Well-being
This is a clinical trial aimed to investigate if a novel phytochemical and fibre-rich snack can improve perimenopausal symptoms and well-being in perimenopausal women aged 40-55 and not on hormone replacement therapy.
- Conditions
- Perimenopause, Perimenopause-Related Depression, Mood, Sleep
- Trial name
- SWAP (NCT07599930)
- Testing
- Functional Snacks
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King's College London
Perimenopausal Bone Loss
Prunes Preventing Bone Loss in Perimenopause
Dietary interventions of prune consumption during the transmenopausal period are innovative methods to prevent bone loss. Modern medicine does not intervene to prevent or attenuate this highly vulnerable period of bone loss…
- Trial name
- Prune-UP (NCT07120997)
- Testing
- Prunes, Calcium supplement, Vitamin D Supplement
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Penn State University
Menopause, Perimenopause
Effects of Hemp-Derived Cannabinoids on Menopause Symptoms
The purpose of the study is to examine the impact of hemp-derived minor cannabinoids on symptoms of menopause/perimenopause.
- Trial name
- NCT07393672
- Testing
- Hemp-derived cannabinoids
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Washington State University
Perimenopausal Women, Body Composition Changes
Nutritional Supplementation on Physiological and Metabolic Markers in Females
The goal of this clinical trial is to learn if a 12-week nutritional supplement can result in significant changes in the body composition of 38-55-year-old females.
- Trial name
- NCT07615777
- Testing
- Nutritional Supplement
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Perimenopause, Aging
Impact of Funcional Exercise and Supplementation in Perimenopausal Women's Health
The goal of this clinical trial is to learn whether a natural-origin nutritional supplement, combined with a functional exercise program, can improve psycho-emotional, cognitive, functional, and neuroendocrine health in…
- Trial name
- NCT07251296
- Testing
- Exercise + nutritional supplement
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- University of Valencia
Estrogen, Premenopause
Disentangling the Effects of Daily Stress, Sleep, and Sex Hormones on Accelerated Vascular Aging in Midlife Women
The purpose of this study is to identify the impact of estradiol (E2) on the associations between (a) responsivity to daily stress or (b) sleep variability with vascular function in midlife premenopausal women.
- Trial name
- V-RISES (NCT06745466)
- Testing
- ganirelix acetate
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Delaware