Clinical trials: Perimenopause
Menopausal, Perimenopause
Creatine HCl and Creatine Ethyl Ester Supplementation in Perimenopausal and Menopausal Women
The goal of this randomized controlled double-blind parallel-group interventional trial is to evaluate the effects of of dietary supplementation with creatine HCl and creatine ethyl ester supplementation on cognitive performance…
- Trial name
- CONCRET-MENOPA (NCT06660004)
- Testing
- Dietary Supplement: Experimental 1 Creatine HCl, Dietary Supplement: Experimental 2 Creatine HCl, Dietary Supplement: Experimental 3 Creatine Ethyl ester
- Where
- Serbia
- Volunteers
- 36 people
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Elevated Blood Pressure, Perimenopause
No Time to Pause: Physical Activity to Improve Health of Midlife Hispanic Women
This study will test the effects of a physical activity intervention among midlife Hispanic women.
- Trial name
- NCT06376812
- Testing
- Physical activity intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Perimenopause, Perimenopausal Depression
A Trial to Investigate the Accuracy of a Wearable Device in Collecting Data Related to Perimenopausal Symptoms in Women
The goal of this observational study is to investigate the accuracy of the device in characterizing perimenopausal and menopausal symptoms including vasomotor symptoms, anxiety, sleep quality compared to self-reported symptoms…
- Conditions
- Perimenopause, Perimenopausal Depression, Perimenopausal Insomnia, Perimenopausal Women
- Trial name
- NCT07022925
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- IdentifyHer Limited
Perimenopause-Related Depression
Estrogen Receptor Beta and Mood
Background: Our previous studies have found that women who had depression during the perimenopause may have mood symptoms again if they stop estrogen therapy.
- Trial name
- NCT03689543
- Testing
- Estradiol, ER Beta Agonist, Provera
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- National Institute of Mental Health (NIMH)
Menopause, Anxiety
Internet-Delivered Cognitive Behaviour Therapy for Women with Perimenopausal Anxiety
The goal of this clinical trial is to design an online Cognitive Behavioural Therapy (CBT) and Acceptance Commitment Therapy (ACT) program and to learn if it can treat anxiety in women transitioning into menopause…
- Conditions
- Menopause, Anxiety, Depressive/Anxiety Symptoms, Perimenopause
- Trial name
- NCT06865066
- Testing
- e-CBT
- Where
- 2 sites in Canada
- Volunteers
- 25 people
- Sponsor
- Dr. Nazanin Alavi
Obese Women, Perimenopause
Anti-obesity Effects of Dandelion (Taraxacum Officinale L.)
The study investigates the effectiveness of the natural product Dandelion in treating obesity in premenopausal women through a randomized interventional trial, measuring various parameters and biomarkers.
- Trial name
- NCT06625736
- Testing
- Xenical, The dandelion extract
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- October 6 University
Menopause, Perimenopause
A Study to Examine the Effects of a Daily Supplement on Common Symptoms of Perimenopause and Menopause
Symptoms of perimenopause and menopause can significantly affect overall quality of life. It is hypothesized that daily supplements can reduce the severity of these symptoms.
- Trial name
- NCT06018740
- Testing
- Daily Balance Gummy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hologram Sciences
Perimenopause, Sexual Concerns
Cognitive Behavioural Therapy for Sexual Concerns During Perimenopause
Given the high rates and associated impairment of sexual concerns during the menopausal transition, and specifically during perimenopause, our team has developed a CBT protocol specifically designed to target these prevalent and…
- Trial name
- NCT04922385
- Testing
- Cognitive Behavioural Therapy
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Insomnia, Perimenopause
Fire Dragon Pot Moxibustion
Insomnia in perimenopausal women is normal. Studies have shown that insomnia occurs in 75-81% of perimenopausal women and is 2.4 times more common than in premenopausal participants.
- Trial name
- NCT05234814
- Testing
- Traditional Chinese Medicine auricular acupuncture point buried seeds therapy plus the fire dragon pot moxibustion therapy., Traditional Chinese Medicine auricular acupuncture point buried seeds therapy
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Weihua Yu
Perimenopause, Menstrual Cramps
Oral Micronized Progesterone Effects on Perimenopausal Menstrual Flow
This study is designed to evaluate the within-woman effect of oral micronized progesterone (Progesterone 300 mg at bedtime) on semi-quantitative menstrual flow measured by the DivaCup® (menstrual cup with volume indicators at…
- Trial name
- NCT02779582
- Testing
- Oral Micronized Progesterone
- Where
- Canada
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Perimenopause, Climacteric Syndrome
Clinical Evaluation of Effectiveness and Safety of Amberen and Smart B in Perimenopausal Women.
To evaluate effectiveness and safety of combined use of dietary supplements Amberen and Smart B in women with a typical (without complications) form of climacteric syndrome, with mild to moderate symptoms in perimenopause.
- Trial name
- NCT03897738
- Testing
- Amberen, Smart B
- Where
- Russia
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Perimenopause
Acupuncture for Relieving Perimenopausal Symptoms
The purpose of this study is to determine whether acupuncture is effective for relieving perimenopausal symptoms.
- Trial name
- NCT01933204
- Testing
- Acupuncture, Climen 21 Tablets
- Where
- 2 sites in China
- Volunteers
- 220 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Turner Syndrome, Ovarian Failure, Premature
Dry Eye in Women With Turner Syndrome and Women With Premature Ovarian Failure
Premature ovarian failure (POF) is known to be associated with an increased risk of ocular surface disease (dry eye), likely due to the reduction of both estrogens and androgens seen in this condition.
- Conditions
- Turner Syndrome, Ovarian Failure, Premature, Sex Chromosome Aberrations, Menopause
- Trial name
- NCT00471731
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Perimenopause, Menopause
Perimenopausal Estrogen Replacement Therapy Study
Study Background and Objectives: In the U.S. the majority of heart disease deaths are in women, not men. Much of the gender disparity in CVD rates relate to the burden of CV risk in women after the menopause.
- Conditions
- Perimenopause, Menopause, Depression
- Trial name
- PERT (NCT01308814)
- Testing
- Estradiol
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Perimenopause, Depression
Effectiveness and Safety of Electro-acupuncture for Mild-to-moderate Perimenopausal Depression
Main objective: to compare the effects of electro-acupuncture and escitalopram oxalate tablets on mild-to-moderate perimenopausal depression, and to evaluate the safety of electroacupuncture stimulation.
- Trial name
- NCT02423694
- Testing
- electro-acupuncture, escitalopram oxalate tablets
- Where
- China
- Volunteers
- 252 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Perimenopause
Oral Contraceptive During Menopausal Transition
Muscle or joint pain is one of the most common symptoms during menopausal transition. As this could be severe enough to affect social and daily life and to reduce quality of life, attentions should be paid about this.
- Trial name
- NCT01414530
- Testing
- oral contraceptive, NSAID
- Where
- South Korea
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Perimenopause
Myo-inositol Plus Melatonin in Perimenopausal Women
Menopause is the milestone of a more broaden condition that can last up to 10 years. The first menopausal symptoms usually appear around the age of 42 and are characterized by a gradual decline in thyroid and gonadal function…
- Trial name
- NCT01325389
- Testing
- Myo-Mel
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre