Clinical trials: Perinatal Outcomes
Postpartum Depression (PPD), Perinatal Anxiety
Midwife-led Childbirth Review and Psychological Outcomes in New Parents
The aim of this clinical trial is to support psychological well-being and facilitate adjustment to parenthood among postpartum mothers and fathers through a midwife-led childbirth review (MLCR).
- Conditions
- Postpartum Depression (PPD), Perinatal Anxiety, Postpartum Mental Health
- Trial name
- CROWN (NCT07678801)
- Testing
- Midwife-led childbirth review (MLCR)
- Where
- 2 sites in Czechia
- Volunteers
- 1,300 people
- Sponsor
- Charles University, Czech Republic
Fetal Clavicle Length, Fetal Scapular Width
Ultrasound Assessment of Fetal Growth Parameters
The goal of this observational study is to establish reference value ranges for normal fetal biometric parameters at different gestational weeks for the domestic population, and evaluate their clinical application to predict…
- Conditions
- Fetal Clavicle Length, Fetal Scapular Width, Fetal Sternal Length, Fetal Scapular Length
- Trial name
- NCT07018362
- Testing
- restricted fetal growth
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Xiamen University
Recurrent Miscarriage
Obstetrics , Prenatal Outcomes in Recurrent Miscarriage
The effect of recurrent miscarriage on the outcome of the current pregnancy and if there's a relation between it and adverse out come
- Trial name
- OBPORPL (NCT06356792)
- Where
- Egypt
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Assiut University
Maternal Mortality, Perinatal Mortality
Evaluation of a Smartphone Application to Reduce Adverse Pregnancy Outcomes in Ethiopia
The purpose of this trial is to determine if the safe delivery smartphone application distributed to health workers in Ethiopia will decrease perinatal mortality and the incidence of postpartum haemorrhage.
- Trial name
- NCT01945931
- Testing
- Safe Delivery Smartphone Application
- Where
- Denmark
- Volunteers
- 3,601 people
- Sponsor
- University of Copenhagen
Gestational Diabetes, High Blood Pressure
Social Deprivation and Pregnancy
Social deprivation during pregnancy is associated to adverse perinatal outcomes. However, prenatal screening of social deprivation by reliable measurement is not performed.
- Conditions
- Gestational Diabetes, High Blood Pressure, Prematurity, Fetal Growth Restriction
- Trial name
- NCT03121196
- Testing
- Epices score
- Where
- France
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Extreme Prematurity - Less Than 28 Weeks, Infant, Extremely Premature
The UK 22 Week Study
In the UK, babies born at 22 weeks of pregnancy have only been offered survival-focused care (sometimes called resuscitation or stabilisation) since 2019.
- Conditions
- Extreme Prematurity - Less Than 28 Weeks, Infant, Extremely Premature, Neonatal and Perinatal Conditions, Intensive Care, Neonatal
- Trial name
- NCT07616778
- Testing
- Not applicable (observational study)
- Where
- 50 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Imperial College London
Preterm Labor With Intact Membranes, Preterm Birth
Effect of Vaginal Progesterone Treatment on Pregnancy and Newborn Outcomes in Women With Preterm Labor
Preterm labor, which occurs when labor starts before 37 weeks of pregnancy, is a major cause of illness and death in newborns. Babies born too early are at higher risk of breathing problems, low birth weight, infections, and…
- Trial name
- NCT07523295
- Testing
- Nifedipine 20 Mg, Dexamethasone, Progesterone 200 mg vaginal capsules
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Medicare Hospital (Pvt) Limited
Neonatal Death, Prematurity
Outcomes Following Early Parenteral Nutrition Use in Preterm Neonates
BACKGROUND An essential part of neonatal care is providing nutrition to ensure that babies grow and develop. Providing this can be difficult in premature babies because their intestines are underdeveloped.
- Trial name
- NCT03767634
- Testing
- Parenteral nutrition
- Where
- United Kingdom
- Volunteers
- 97,507 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Fetal Growth Retardation
Doppler at the Diagnosis in Predicting Perinatal Outcomes in Early and Late-onset Fetal Growth Restriction
When a FGR is diagnose, the challenge in his monitoring is to assess the benefit-risk balance between continuing the pregnancy in order to limit complications related to prematurity and birth in order to minimize any risk of…
- Trial name
- NCT05696223
- Testing
- Ultrasound
- Where
- France
- Volunteers
- 220 people
- Sponsor
- Central Hospital, Nancy, France
COVID-19
Coronavirus Disease 2019 (COVID-19) During Pregnancy: Prevalence of Seroconversion, Effect on Maternal and Perinatal Outcomes and Risk of Vertical Transmission (COVID-MAP)
The objectives of this proposal are to: 1) determine the rate of SARS-CoV-2 seroconversion in unselected pregnant women in Hong Kong; 2) determine the rate of SARS-CoV-2 infection in women presenting with miscarriage and…
- Trial name
- NCT04465474
- Testing
- Non Intervention
- Where
- 10 sites in China, Hong Kong and 1 more
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Infant, Premature, Erythropoietin
High-Dose Erythropoietin in Extremely Premature Infants to Prevent/Attenuate Brain Injury: A Phase II Study
The highest risk for perinatal brain injury occurs among extremely premature infants who weigh less than 1250 grams at birth. Such perinatal brain injury is currently irreversible, associated with neurodevelopmental disability…
- Conditions
- Infant, Premature, Erythropoietin, Brain Injury, Intraventricular Hemorrhage
- Trial name
- NCT00589953
- Testing
- Erythropoietin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Maternal and Child Health Outcomes
Moms and Babies Health and Well-being
The goal of this clinical trial is to see how giving direct cash support affects the health of pregnant women and their babies in the U.S.
- Trial name
- MBHW (NCT06923371)
- Testing
- Direct Cash Support for Maternal and Infant Health (High fee), Behavioral: Direct Cash Support for Maternal and Infant Health (Low fee)
- Where
- United States
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Columbia University
Perinatal Anxiety
Antenatal Bre-Lax Education for Perinatal Anxiety Reduction and Self-efficacy Among Pregnant Women in Karachi's Urban Slums
Background Pregnant women in urban slums experience heightened stress and anxiety due to poor living conditions, limited healthcare access, and weak social support systems.
- Trial name
- NCT07787000
- Testing
- Arm 2: BreLax Intervention Group 1, Arm 3: Combined Intervention Group 3
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Bahria University
Idiopathic Polyhydramios Cases
Cerebroplacental Ratio and Perinatal Outcomes in Mild and Moderate Idiopathic Polyhydramios Cases
This study aims to evaluate the predictability of fetal Doppler parameters in terms of perinatal adverse outcomes in singleton pregnancies with mild and moderate idiopathic polyhydramnios
- Trial name
- NCT06211855
- Testing
- doppler assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Preeclampsia
Physical Therapy in Pregnant Women With Preeclampsia
The aim of this study is to evaluate the influence that has a physical therapy protocol in maternal and fetal hemodynamics in relation to blood pressure, maternal and fetal responses and perinatal outcomes.
- Trial name
- FPE (NCT01630772)
- Testing
- Physical therapy, No physical therapy
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Compare 2 Models of Midwifery Care in Maternity Care
Personalized Support Care in Alternative Midwifery Birth Units Versus Traditional Units in France : Effects on Perinatal Health and Outcomes
Most pregnancies and deliveries in France occur without complication. According to the 2016 Perinatal Survey, 2/3 of births are carried out by spontaneous vaginal delivery with midwife support in most cases.
- Trial name
- PhysioCare (NCT05483101)
- Testing
- Alternative birth units
- Where
- 3 sites in France
- Volunteers
- 597 people
- Sponsor
- Rennes University Hospital
Advanced Maternal Age Pregnancy, Early Pregnancy
Very Advanced Maternal Aged Pregnants and Early Adolescent Pregnant Women
Maternal age is an important factor affecting the pregnancy process and its results. Adverse obstetric outcomes such as preterm birth, stillbirth, and infant mortality are more common in women older than 35 years and younger than…
- Trial name
- NCT05484869
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Siirt University
Infant Mortality, Preterm Birth
Antenatal Micronutrient Supplementation and Infant Survival
The purpose of this community-based randomized trial is to examine whether a daily antenatal and postnatal multiple micronutrient supplement given to women will enhance newborn and infant survival and health and other birth…
- Conditions
- Infant Mortality, Preterm Birth, Low Birth Weight, Neonatal Mortality
- Trial name
- JiVitA-3 (NCT00860470)
- Testing
- Iron (27 mg) - folic acid (600 ug), Multiple micronutrient
- Where
- 2 sites in United States, Bangladesh
- Volunteers
- 44,567 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Hypertension in Pregnancy
Perinatal Outcomes in Patients With Elevated sFlt-1/PlGF Ratio
Retrospective cohort study that evaluated 190 subjects admitted with diagnosis of hypertensive disorder of pregnancy, between 24 and 36 6/7 weeks, with an sFlt-1/PlGF index greater than or equal to 110.
- Trial name
- NCT06403722
- Testing
- Standard of care
- Where
- Panama
- Volunteers
- 190 people
- Sponsor
- Saint Thomas Hospital, Panama
HIV/AIDS
Neuropsychological Outcomes of Internationally-Adopted Children Who Are Perinatally-Infected With Human Immunodeficiency Virus
Children who are perinatally-infected with HIV are extremely vulnerable to cognitive delays and psychiatric disease, and the risk for neuropsychiatric illness is compounded in children who are internationally-adopted and may have…
- Trial name
- NCT03100331
- Testing
- Neuropsychological testing
- Volunteers
- 17 people
- Sponsor
- Corewell Health West