Clinical trials: Perineal Wound Healing
Perineal Pain
Comparison Between Virtual Reality and Stress Ball Intervention In Managing Pain During Episiotomy Repair
This study is a four-arm randomized controlled trial designed to evaluate the effectiveness of non-pharmacological interventions for pain management during episiotomy repair among women undergoing vaginal birth.
- Trial name
- NCT07499011
- Testing
- virtual reality, stress ball, Virtual Reality Plus Stress Ball
- Where
- Iraq
- Volunteers
- 112 people
- Sponsor
- University of Baghdad
Dehiscence Wound, Secondary Perineal Tear
Conservative Treatment or Resuturing Among Women With Perineal Wound Dehiscence After Vaginal Labour
The goal of this observational study is to make us more aware of the short and long-term outcomes for women having an uncomplicated healing process after a rupture or birth cut in the perineum after giving birth in relation to a…
- Conditions
- Dehiscence Wound, Secondary Perineal Tear, Episiotomy; Dehiscence
- Trial name
- HEAL (NCT06026423)
- Testing
- Clinical examination and pictures, Questionnaire
- Where
- Denmark
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Pain
Continuous Versus Interrupted Sutures for Repair of Episiotomy or Second Degree Tears: a Randomised Controlled Trial
The best technique for this repair would be that which requires least time in realisation, least consumption of material for the repair and that which produces less pain at short and long-term permitting the resumption of…
- Trial name
- NCT00777270
- Testing
- repair of episiotomy or second degree tears
- Where
- Spain
- Volunteers
- 445 people
- Sponsor
- Hospital Universitario Principe de Asturias
Perineal Injury
The Use of St. John's Wort Oil With Massage in the Perineum During Childbirth
Perineal trauma, whether spontaneous or episiotomy, is a condition that affects the quality of life in primiparous women . In women who have experienced perineal trauma, problems such as dyspareunia, urinary and fecal…
- Trial name
- NCT05164926
- Testing
- perineal massage with St. John's Wort oil
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Second Stage of Labor
Searching for the Perfect Oil to Protect the Perineum: A Randomized-Controlled, Double-Blind Trial
In this study we intend to randomly assign each parturient one of two commonly used oils to be applied during the second stage of labor, one of them containing vitamin E.
- Trial name
- NCT00662974
- Testing
- perineal massage with Wheat Germ Oil during the second stage of labor, perineal massage with almond oil during the second stage of labor
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Perineal Tear
Lidocaine, Povidone Iodine, and Honey Application on Second-degree Perineal Tear Healing
This clinical trial aims to compare the effectiveness of the continuous application of lidocaine cream, honey, and povidone-iodine cream in second-degree perineal tear healing.
- Trial name
- NCT05946005
- Testing
- honey, lidocaine, povidone-iodine
- Where
- Indonesia
- Volunteers
- 200 people
- Sponsor
- Hasanuddin University
Cesarean Section; Infection, Perineal Infection
Effect of Copper on the Healing of Obstetric Wounds
The most common complication of vaginal delivery is perineal tearing with a prevalence of 85% and 70% will need suturing. The caesarean section rate worldwide is rising and the rate in Croydon University Hospital is in the region…
- Conditions
- Cesarean Section; Infection, Perineal Infection, Wound Infection, Surgical Site Infection
- Trial name
- ECHO (NCT03284749)
- Testing
- Copper impregnated wound dressing, Normal wound dressing, Copper impregnated maternity pads
- Where
- United Kingdom
- Volunteers
- 774 people
- Sponsor
- Croydon Health Services NHS Trust
Perineal Trauma, Postpartum Pain
RELIEVE Study- Platelet-Rich Plasma to Reduce Postpartum Pain After Perineal Tears or Episiotomy
Perineal tears and episiotomies are common after vaginal birth and may cause persistent pain, impaired wound healing, pain during sexual activity, and concerns about genital appearance.
- Conditions
- Perineal Trauma, Postpartum Pain, Episiotomy, Perineal Laceration
- Trial name
- RELIEVE (NCT07727213)
- Testing
- Autologous Non-Activated Platelet-Rich Plasma, Saline (0.9%, sterile, for infusion)
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- University Hospital, Geneva
Perineal Lacerations, Episiotomy
Study of Different Suturing Techniques for Perineal Repair After Delivery
We wish to determine wich of two standardized suturing techniques is the best for perineal repair if a perineal laceration or an episiotomy is present after vaginal birth.
- Trial name
- NCT00265421
- Testing
- Suture technique for perineal repair after delivery
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pregnancy Complications, Infectious
Antibiotics for Postpartum Third and Fourth Degree Perineal Tear Repairs
This study is undertaken to find out whether prophylactic antibiotics can decrease the infection rate in third and fourth degree perineal tear repairs done in the immediate postpartum period.
- Trial name
- NCT00186082
- Where
- 2 sites in United States
- Volunteers
- 147 people
- Sponsor
- Stanford University
Rectal Prolapse
TEM Assisted Perineal Rectopexy in Treatment of Rectal Prolapse
Curvilinear incision in the postanal space, through the intersphincteric plane, insertion of Proctoscope of TEM technique and dissection till sacral promontory, insertion of mesh between the rectum and sacrum, post anal repair…
- Trial name
- NCT02609555
- Testing
- TEM perineal rectopexy
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Mansoura University
Episiotomy, Platelet Rich Plasma (PRP)
Platelet-Rich Plasma Versus Standard Care for Episiotomy Wound Healing in Postpartum Women
This study looks at whether a treatment made from a patient's own blood, called platelet-rich plasma (PRP), can help heal the cut made during childbirth (episiotomy) better than standard care alone.
- Conditions
- Episiotomy, Platelet Rich Plasma (PRP), Wound Healing, Obstetric
- Trial name
- PRP-EpiHeal (NCT07669285)
- Testing
- Autologous Platelet-Rich Plasma (PRP), Standard Wound Care
- Where
- Romania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Saint Andrew Hospital Constanta
Improving Quality of Life
Pain Relief During Repair of Postpartum Perineal Tears
The aim of our study is to compare the analgesic effect of topical application of lidocaine-prilocaine cream and lidocaine infiltration during repair of postpartum perineal tears.
- Trial name
- LPPT (NCT02883179)
- Testing
- lidocaine injection, lidocaine-prilocaine cream
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Assiut University
Perineal Wound Complications After ELAPE
Pelvic Floor Reconstruction Using Biological Mesh With Negative Pressure Wound Therapy Following ELAPE
Perineal wound healing is a significant challenge after extralevator abdominoperineal excision (ELAPE) due to a high rate of wound breakdown.
- Trial name
- NCT04033484
- Testing
- Negative Pressure Wound Therapy
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Beijing Chao Yang Hospital
Vaginal Laceration During Delivery
The PAIN (Pelvic Area Injection for Numbness) Study
Postpartum pain can interfere with patient's ability to care for themselves, and their newborn, and untreated pain is associated with risk of greater opioid use, postpartum depression, and development of persistent pain.
- Trial name
- PAIN (NCT05972681)
- Testing
- Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Perineal Laceration Repair
Comparison of Absorbable Sutures in Perineal Laceration Repair
The purpose of this study is to determine the difference in pain scales between absorbable suture types for second-degree perineal laceration repair.
- Trial name
- NCT00223119
- Testing
- Absorbable Sutures
- Where
- United States
- Sponsor
- Medtronic - MITG
Fourth Degree Perineal Laceration Involving Anal Mucosa, Obstetric; Injury
Use of the Modified Beef Tongue Model for Teaching Repair of Obstetrical Fourth-Degree Laceration to Residents
This is a study evaluating the use of the modified beef tongue model for teaching repair of obstetrical fourth-degree laceration to residents.
- Conditions
- Fourth Degree Perineal Laceration Involving Anal Mucosa, Obstetric; Injury, Obstetric Labor Complications
- Trial name
- NCT03341351
- Testing
- Instructional video, Instructional workshop
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Wound Heal, Abdominoperineal Resection
Gluteal Turnover Flap for Closure of the Perineal Wound After Abdominoperineal Resection for Rectal Cancer
Background: About 700 patients per year undergo an abdominoperineal resection (APR) for distal rectal cancer (Dutch Colorectal Audit 2016).Neoadjuvant (chemo)radiotherapy is often used to further improve locoregional control.
- Conditions
- Wound Heal, Abdominoperineal Resection, Rectal Cancer
- Trial name
- BIOPEX2 (NCT04004650)
- Testing
- Gluteal turnover flap
- Where
- Netherlands
- Volunteers
- 160 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Adenocarcinoma (NOS)
Evaluation of the Efficacy of Negative Pressure Wound Therapy on Perineal Healing Following Abdominoperineal Amputation
Abdomino-perineal resection is a surgical procedure involving the removal of the rectum and anus via abdominal and perineal approaches. During this procedure, a terminal colostomy is created and the perineum is closed.
- Trial name
- AAPICO (NCT07489820)
- Testing
- Direct perineal skin suturing with negative pressure wound therapy (PICO 7®), Direct perineal skin suture
- Where
- 5 sites in France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Perineum; Wound, Postoperative Complications
Reconstruction After Abdominoperineal Resection With Robot-assisted Harvest of VRAM Flap
Non-randomized study of robot-assisted perineal reconstruction with rectus abdominis muscle flap in patients operated with abdominoperineal resection for irradiated locally advanced rectal or anal cancer.
- Conditions
- Perineum; Wound, Postoperative Complications, Rectal Neoplasms, Rectus Abdominis Hernia
- Trial name
- NCT05689775
- Testing
- Reconstruction with robot-assisted rectus abdominis muscle flap
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital