Clinical trials: Perineum; Injury
Perineal Wound Complications After ELAPE
Pelvic Floor Reconstruction Using Biological Mesh With Negative Pressure Wound Therapy Following ELAPE
Perineal wound healing is a significant challenge after extralevator abdominoperineal excision (ELAPE) due to a high rate of wound breakdown.
- Trial name
- NCT04033484
- Testing
- Negative Pressure Wound Therapy
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Beijing Chao Yang Hospital
Perineum; Tear, Traumatic, Anal Tear
Perineal Trauma After Jet Ski Accidents and Long-term Functional Outcomes Results
French multicentric retrospective cohort study including patients who underwent an ano-perineal trauma following a personal watercraft/jet-ski accident and that were treated in France from January 2017 to December 2023.
- Conditions
- Perineum; Tear, Traumatic, Anal Tear, Anal Incontinence
- Trial name
- TP-JET (NCT06368284)
- Testing
- Patients who experienced an ano-perineal trauma following a PWC/Jet-Ski accident
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Pelvic Floor Disorders, Pelvic Floor; Perineal Rupture, Obstetric
The Effect of a Postpartum Training Program on Women Who Have Suffered a Levator Ani Injury.
The goal of this pilot randomized pilot controlled trial (RTC)is to collect acceptability and feasibility outcomes of a physiotherapy individualized program in women with levator injury that is intended to be used in a larger…
- Conditions
- Pelvic Floor Disorders, Pelvic Floor; Perineal Rupture, Obstetric, Physiotherapy
- Trial name
- NCT05617092
- Testing
- Physiotherapy treatment
- Where
- Sweden
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Anal Sphincter Injury
The Effect of Episiotomy on Maternal and Fetal Outcomes (EPITRIAL)
This study is aimed to evaluate the influence of episiotomy on various maternal and neonatal outcomes. Half of the participants will undergo selective episiotomy (according to routine delivery management at the particular…
- Trial name
- NCT02356237
- Testing
- No episiotomy
- Where
- Israel
- Volunteers
- 676 people
- Sponsor
- Lena Sagi-Dain
Perineal Trauma, Ritgen Maneuver
Ritgen Maneuver and Birth-Related Perineal Trauma: RCT
Perineal trauma is one of the common complications that may occur during the second stage of labor and can negatively affect women's postpartum recovery and quality of life.
- Trial name
- NCT07713173
- Testing
- Ritgen maneuver, Routine Care Group
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Medipol University
Maternal Pushing Techniques, Perineal Trauma
Vocalization and Spontaneous Pushing in the Second Stage of Labor
The second stage of labor, defined as the period from full cervical dilatation to fetal birth, is a critical phase in which maternal pushing techniques may significantly affect maternal and neonatal outcomes (1-5).
- Conditions
- Maternal Pushing Techniques, Perineal Trauma, Maternal Fatigue, Labor
- Trial name
- NCT07316348
- Testing
- The vocalization straining technique will be used.
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Perineal Tear, Perineal Laceration (Obstetric)
Comparison Between Rectal Suppository Acetaminophen and Diclofenac Sodium as Analgesia for Postpartum Perineal Tear
To assess the prevalence of pain score for perineum pain following childbirth followed by phase 2 study to assess the analgesic effectiveness of acetaminophen and diclofenac rectal suppository in postpartum perineum pain…
- Trial name
- SuPPerP (NCT03041779)
- Testing
- Diclofenac Sodium 50Mg Suppository, Paracetamol 500Mg Suppository
- Volunteers
- 909 people
- Sponsor
- Clinical Research Centre, Malaysia
Perineal Laceration Repair
Comparison of Absorbable Sutures in Perineal Laceration Repair
The purpose of this study is to determine the difference in pain scales between absorbable suture types for second-degree perineal laceration repair.
- Trial name
- NCT00223119
- Testing
- Absorbable Sutures
- Where
- United States
- Sponsor
- Medtronic - MITG
Fourth Degree Perineal Laceration Involving Anal Mucosa, Obstetric; Injury
Use of the Modified Beef Tongue Model for Teaching Repair of Obstetrical Fourth-Degree Laceration to Residents
This is a study evaluating the use of the modified beef tongue model for teaching repair of obstetrical fourth-degree laceration to residents.
- Conditions
- Fourth Degree Perineal Laceration Involving Anal Mucosa, Obstetric; Injury, Obstetric Labor Complications
- Trial name
- NCT03341351
- Testing
- Instructional video, Instructional workshop
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Perineal Injury, Perineal Pain
TECAR in the Management of Early Postpartum Perineal Pain.
The study aimed to evaluate the effect of TECAR (Capacitive and Resistive Energy Transfer) therapy on the level of pain and discomfort in the pelvic floor in women after an episiotomy or perineal tears, during the first two days…
- Conditions
- Perineal Injury, Perineal Pain, Vaginal Delivery, Instrumental Delivery
- Trial name
- NCT07730372
- Testing
- TECAR - Capacitive and Resistive Energy Transfer
- Where
- Poland
- Volunteers
- 182 people
- Sponsor
- Medical University of Gdansk
Pain, Postpartum Depression
Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries
Obstetric anal sphincter injuries (OASIS) encompass both third and fourth degree perineal tears. These tears can have a significant impact on women's quality of life in the short and long term.
- Trial name
- NCT03470675
- Testing
- Epidural saline + IV saline, Epidural morphine 3 mg + IV saline, Epidural morphine 3 mg + IV ketamine 0.3 mg/kg
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Northwestern University
Birth Injuries
The Effect of Primary Delivery of the Anterior Compared With the Posterior Shoulder on Perineal Trauma: a Randomized Controlled Trial
It is unknown if primary delivery of the anterior or the posterior shoulder causes less perineal tear. The objective of this trial is to evaluate the incidence and degree of perineal trauma after primary delivery of the anterior…
- Trial name
- NCT01937546
- Testing
- Primary delivery of anterior shoulder, Primary delivery posterior shoulder
- Where
- Denmark
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Holbaek Sygehus
Wound Heal, Abdominoperineal Resection
Gluteal Turnover Flap for Closure of the Perineal Wound After Abdominoperineal Resection for Rectal Cancer
Background: About 700 patients per year undergo an abdominoperineal resection (APR) for distal rectal cancer (Dutch Colorectal Audit 2016).Neoadjuvant (chemo)radiotherapy is often used to further improve locoregional control.
- Conditions
- Wound Heal, Abdominoperineal Resection, Rectal Cancer
- Trial name
- BIOPEX2 (NCT04004650)
- Testing
- Gluteal turnover flap
- Where
- Netherlands
- Volunteers
- 160 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Adenocarcinoma (NOS)
Evaluation of the Efficacy of Negative Pressure Wound Therapy on Perineal Healing Following Abdominoperineal Amputation
Abdomino-perineal resection is a surgical procedure involving the removal of the rectum and anus via abdominal and perineal approaches. During this procedure, a terminal colostomy is created and the perineum is closed.
- Trial name
- AAPICO (NCT07489820)
- Testing
- Direct perineal skin suturing with negative pressure wound therapy (PICO 7®), Direct perineal skin suture
- Where
- 5 sites in France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Sexual Violence, Woman Abuse
Consequences of Sexual Violence Among Women Living in Democratic Republic of Congo
In conflict situations, sexual violence (SV) used can take various forms, including rape and female genital mutilation (FGM). SV is used as a strategic weapon to shake, terrorize, and displace communities and thus take control of…
- Conditions
- Sexual Violence, Woman Abuse, Perineal Injury
- Trial name
- SV-RDC (NCT05731297)
- Where
- Democratic Republic of the Congo
- Volunteers
- 742 people
- Sponsor
- Bertuit Jeanne
Sphincter Ani Incontinence, Obstetric Trauma
Physical Therapy for Women With Obstetric Trauma and Anal Incontinence
Our primary objective is to determine if physical therapy (PT) and behavioral therapy (BT) in the post-partum period after a vaginal delivery complicated by genital trauma help to improve a woman's quality of life, specifically…
- Trial name
- NCT01672697
- Testing
- Physical Therapy (PT) and Behavioral Therapy (BT)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- TriHealth Inc.
Bowel Cleansing Prior to Clinical Procedures, Colorectal Anastomosis
Oral Antibiotics vs. No Antibiotics in Pediatric Colorectal Surgery
This study aims to evaluate whether giving oral antibiotics before elective colorectal surgery can improve recovery and reduce complications in children.
- Trial name
- PEACO (NCT07713433)
- Testing
- oral antibiotics, No Oral Antibiotics
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Muhammad Zubair Shoukat
Perineum; Wound, Postoperative Complications
Reconstruction After Abdominoperineal Resection With Robot-assisted Harvest of VRAM Flap
Non-randomized study of robot-assisted perineal reconstruction with rectus abdominis muscle flap in patients operated with abdominoperineal resection for irradiated locally advanced rectal or anal cancer.
- Conditions
- Perineum; Wound, Postoperative Complications, Rectal Neoplasms, Rectus Abdominis Hernia
- Trial name
- NCT05689775
- Testing
- Reconstruction with robot-assisted rectus abdominis muscle flap
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Perineal Injury, Pain
Epsom Salt Compresses to Relieve Perineal for Postpartum Care: a Clinical Trial
The goal of this clinical trial is to determine if topical application of compresses soaked in 25% magnesium sulfate on painful perineum after birth is effective to alleviate pain.
- Trial name
- NCT06393608
- Testing
- Epsom salt, Water
- Where
- 4 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Antoine Roger
Birth Trauma
Video Analysis of Vaginal Deliveries
Video documentation of vaginal deliveries to evaluate the impact of the support of the perineum
- Trial name
- NCT02295904
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zurich