Clinical trials: Periodontal Atrophy
Gingival Recession
Areal and Linear Comparison of Gingival Recession
Recent advances in digital technology have led to the emergence of precise methods for measuring gingival recession and tissue thickness.
- Trial name
- agr (NCT06502782)
- Testing
- digital assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Alveolar Bone Loss
Use of Hyaluronic Acid as a Therapeutic Strategy for Bone Repair in Human
The aim of this study is to evaluate the effects of hyaluronic acid (HA) on bone healing in human dental sockets.
- Trial name
- NCT02709525
- Testing
- hyaluronic acid
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Obstructive Sleep Apnea of Adult, Periodontal Diseases
Periodontal Disease in Patients With Obstructive Sleep Apnea
Investigators hypothesize that in patients with obstructive sleep apnea (OSA) the severity of periodontal disease is significantly higher compared to patients without OSA in every aspect, including PI, PD, CAL and BOP.
- Conditions
- Obstructive Sleep Apnea of Adult, Periodontal Diseases, Periodontal Pocket, Periodontal Attachment Loss
- Trial name
- NCT04581798
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Maxillary Sinus Disease, Periodontal Bone Loss
Association Between Periodontal Bone Loss and Maxillary Sinus Changes.
AIM AND OBJECTIVES: AIM To determine the association between periodontal bone loss and maxillary sinus changes through cone beam computed tomography. OBJECTIVES Primary objectives- 1.
- Trial name
- NCT04702867
- Where
- India
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Recessions
Development of an Artificial Intelligence-Based Clinical Image Model for Detection, Classification, and Management Recommendations of Anterior Gingival Recession
This study aims to develop and evaluate an artificial intelligence-based clinical image model for the detection, classification, and management recommendations of anterior gingival recession.
- Trial name
- NCT07693322
- Testing
- Artificial Intelligence-Based Clinical Image Analysis Model
- Where
- Egypt
- Volunteers
- 149 people
- Sponsor
- Al-Azhar University
Gingival Recession
Treatment of Gingival Recession Using Gingival Composite Restoration Versus Coronally Advanced Flap
Treatment of gingival recession requires favourable anatomical conditions and the use of invasive surgical approaches. Hence, these procedures are not always indicated in all cases and can cause great pain and morbidity.
- Trial name
- NCT04584931
- Testing
- coronally advanced flap, restorative intervention
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Root Coverage in Smokers With Acellular Dermal Matrix Graft and Enamel Matrix Derivative
Smoking has a negative effect on the predictability and stability of root coverage procedures because of decreased blood supply and fibroblast activity.
- Trial name
- NCT02135471
- Testing
- acellular dermal matrix graft, enamel matrix derivative
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- University of Sao Paulo
Gingival Recession
Collagen Matrix With and Without Enamel Matrix Derivative
The purpose of this prospective, double-blinded, randomized, split-mouth study is to compare the effectiveness of a porcine collagen matrix (CM) and coronally advanced flap (CAF) with or without the addition of enamel matrix…
- Trial name
- NCT03467802
- Testing
- enamel matrix derivative, Porcine collagen matrix
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Walter Reed National Military Medical Center
Alveolar Bone Loss
Khoury Technique Versus Titanium Reinforced PTFE Membrane in 3D Alveolar Bone Augmentation
In patients with missed lower posterior teeth and resorbed lower jaw, the study aimed at restoring the jaw's height and width to accommodate placing dental implants.
- Trial name
- NCT06209905
- Testing
- Alveolar ridge augmentation
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Tooth Loss, Recession, Gingival
Use of Leucocyte- and Platelet-rich Fibrin Membranes in Single Implant
The objective of this randomized controlled clinical trial is to evaluate the increase of soft tissue thickness around single implants installed in maxillary esthetic area with the use of Leucocyte-Platelet rich Fibrin (L-PRF)…
- Trial name
- NCT03660566
- Testing
- Test - Implant with L-PRF, Control - Implant without L-PRF
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Connective Tissue, Gingiva
Comparison of Free Gingival Graft and Linear Incision for Connective Tissue
A randomized controlled non-inferiority trial will be conducted with 24 individuals aged 18 or older, who are periodontally healthy and require root coverage in bilateral multiple RT1-type recessions involving at least two teeth…
- Conditions
- Connective Tissue, Gingiva, Gingival Recession, Humans
- Trial name
- NCT06365983
- Testing
- Connective Tissue with Free Gingival Graft, Connective Tissue with Linear Incision
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Recession, Gingival
Soft Tissue Augmentation Around Immediate Implants In The Esthetic Zone
Following tooth loss, a considerable reduction in hard- and soft-tissue volume can be expected (Tan WL, et al., 2012), (AraujoMG, et al., 2015).
- Trial name
- NCT03802370
- Testing
- connective tissue grafting by Dome Technique
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries, Erosive Tooth Wear
New In Situ Model Design for Caries and Erosion
This study will test simultaneously and independently two novel in situ models, one for caries and one for erosive tooth wear (ETW), based on the simulation of these dental conditions on enamel specimens placed on 3D-printed…
- Trial name
- NCT07849270
- Testing
- 0 ppm fluoride toothpaste, 250 ppm fluoride toothpaste (dose-response control), 1150 ppm fluoride toothpaste
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Indiana University
Gingival Recession
Gingival Recession Treatment With Concentrated Growth Factor(CGF)
Platelet concentrates(PC) are used in the field of periodontology and implantology for the content necessary key cells and growth factors to accelerate healing and to provide regeneration.
- Trial name
- NCT03020732
- Testing
- test groups, control groups
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Gazi University
Gingival Recession
Tunnel Technique With Emdogain® in Addition to Connective Tissue Graft Compared With Connective Tissue Graft Alone for the Treatment of Gingival Recessions: a Randomized Clinical Trial.
Microsurgical tunneling flap procedures using connective tissue grafts (CTG) are predictable for treating teeth with gingival recessions.
- Trial name
- NCT03354104
- Testing
- The tunnel technique for root coverage with Emdogain, The tunnel technique for root coverage without Emdogain
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Warsaw
Gingival Recession, Generalized
NovoMatrix in Gingival Recession Coverage: Case Series
Twenty patients seeking treatment for gingival recession coverage, ranging from 20-70 years of age with multiple Miller Class I or II buccal gingival recessions (depth≥3 mm, at least 3 adjacent teeth) will be recruited for this…
- Trial name
- NCT06409468
- Testing
- Subperiostal tunnel in conjunction with Novomatrix
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Gingival Recession
Facial Mucosal Level Determinants for Single Immediately Placed Implants Evaluated by Novel Ultrasonography
A single center, prospective clinical trial is planned to investigate the effect of different emergence angles of implant restorations on peri-implant soft tissue recession and implant marginal bone loss.
- Trial name
- NCT03558282
- Testing
- Recession Observation, Crown Contour Observation
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Michigan
Tooth Loss, Dental Implant Failed
Investigation of the Effect of Horizontal Platelet Rich Fibrin Placed in Tooth Extraction Sockets on Bone Formation
Dental implants, the treatment of complete and partial edentulous cases involving the restoration of lost teeth, have become a registered and widely used treatment option.
- Conditions
- Tooth Loss, Dental Implant Failed, Alveolar Bone Loss
- Trial name
- NCT07011303
- Testing
- H-PRF, L-PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University