Clinical trials: Periodontal Attachment Loss
Periodontal Diseases, Diabetes Mellitus, Type 2
Antimicrobial Photodynamic Therapy in Patients With Periodontal Disease and Type 2 Diabetes Mellitus
Objectives: This study aimed to determine the effect of concomitant antimicrobial photodynamic therapy (aPTD) on periodontal disease and glycaemic control in patients with type 2 diabetes mellitus (T2DM).
- Conditions
- Periodontal Diseases, Diabetes Mellitus, Type 2, Periodontitis, Periodontal Pocket
- Trial name
- NCT05816941
- Testing
- Conventional Periodontal Treatment (Complete Oral Disinfection), Adjunctive Photodynamic Therapy
- Volunteers
- 24 people
- Sponsor
- University of Ljubljana
Periodontal Attachment Loss
ESWT on Human Gingival Fibroblasts
The idea of treating different deformities or diseases in the maxillofacial region with Extracorporeal Shockwave Therapy (ESWT) has recently become popular.
- Trial name
- ESWT (NCT05766293)
- Testing
- extracorporeal shockwave device, Fibroblast cell lines not subjected to shockwaves from extracorporeal shockwave device
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Dr Prabhuji MLV
Periodontal Diseases, Periodontal Pocket
Manuka Honey as an Adjunct to Non-surgical Periodontal Therapy: Clinical Study
The goal of this split-mouth clinical trial is to evaluate the effects of Manuka honey applied into periodontal pockets after initial periodontal therapy (NSPT) in the treatment of stage 3 periodontitis.
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontal Bone Loss, Periodontal Attachment Loss
- Trial name
- NCT05631600
- Testing
- Manuka honey
- Where
- Croatia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Periodontitis, Diabetes Mellitus, Type 2
A Danish Nationwide Longitudinal Study on Prevalence of Periodontitis and Its Co-morbidities
The project (PlanPerioMed) is a register-based study evaluating the associations and patterns of health care delivery between periodontitis and medical diseases using data from the Danish dental record system Dentalsuite…
- Conditions
- Periodontitis, Diabetes Mellitus, Type 2, Cardiovascular Diseases, Rheumatoid Arthritis
- Trial name
- PlanPerioMed (NCT05574231)
- Testing
- Periodontal treatment
- Volunteers
- 4,000,000 people
- Sponsor
- University of Copenhagen
Gingival Recession, Periodontal Attachment Loss
Flap Thickness Upon Root Coverage With the Use of Acellular Dermal Matrix
OrACell has been tested as a barrier in bone regenerative procedures showing promising results in new bone formation after socket preservation, but no data is available on root coverage procedures.
- Conditions
- Gingival Recession, Periodontal Attachment Loss, Periodontal Diseases, Soft Tissue Injuries
- Trial name
- NCT04802473
- Testing
- Mucogingival surgery
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Periodontitis Stage I, Periodontal Diseases
Effect of Adjunctive Use of Vitamin B3 and B9 on Myeloperoxidase Level in the GCF of Patients With Stage I and II Periodontitis
this study addresses the effect of the vitamin B3 and vitamin B9 on the periodontal healing at the sites of periodontal destruction due to periodontitis and evaluate its added effect to the conventional non-surgical periodontal…
- Conditions
- Periodontitis Stage I, Periodontal Diseases, Periodontal Inflammation, Periodontal Attachment Loss
- Trial name
- NCT05435378
- Testing
- Vitamin B3 100 MG Oral Tablet, vitamin B9, full mouth non surgical periodontal treatment
- Volunteers
- 30 people
- Sponsor
- Cairo University
Periodontal Diseases, Periodontal Attachment Loss
Low-level Laser Therapy as an Adjunct to Non-surgical Periodontal Treatment
The present study aimed to investigate the effects of low-level laser therapy (LLLT) as an adjunct to non-surgical periodontal treatment (NSPT) on the plasminogen-activating system in Stage 3-4, Grade C periodontitis patients.
- Conditions
- Periodontal Diseases, Periodontal Attachment Loss, Periodontal Disease, AVDC Stage 3, Periodontal Inflammation
- Trial name
- NCT05233501
- Testing
- low level laser therapy, non-surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Obstructive Sleep Apnea of Adult, Periodontal Diseases
Periodontal Disease in Patients With Obstructive Sleep Apnea
Investigators hypothesize that in patients with obstructive sleep apnea (OSA) the severity of periodontal disease is significantly higher compared to patients without OSA in every aspect, including PI, PD, CAL and BOP.
- Conditions
- Obstructive Sleep Apnea of Adult, Periodontal Diseases, Periodontal Pocket, Periodontal Attachment Loss
- Trial name
- NCT04581798
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Periodontal Attachment Loss, Periodontal Bone Loss
Added Benefit of L-PRF to Autogenous Bone Graft in the Treatment of Mandibular Degree II Furcation Defects
Different therapeutic approaches have been proposed for the treatment of furcation defects and the regeneration of periodontium within the furcation area is considered one of the most challenging aspect of surgical periodontal…
- Trial name
- NCT03756493
- Testing
- Periodontal Surgery with OFD+ABG+L-PRF, Periodontal Surgery with OFD+ABG, Periodontal Surgery OFD
- Where
- Italy
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Periodontitis, Localized Aggressive, Periodontal Diseases
Accuracy of Pulp Sensibility Test on Teeth With Deep Periodontal Pocket
The aim of this study is to evaluate the accuracy of pulp test in teeth presenting with deep periodontal pocket. The null hypothesis is no significant effect of periodontitis on the accuracy of pulp test.
- Conditions
- Periodontitis, Localized Aggressive, Periodontal Diseases, Endodontic Disease, Endodontic Inflammation
- Trial name
- NCT04399135
- Testing
- Orthopantomogram X-ray view, Endo-Ice, Electric Pulp Tester (EPT)
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Qassim University
Anxiety Disorders, Oral Disease
Effect of Trait Anxiety in Women on Oral Health Status and Oral Health Care-Seeking Behavior
Trait anxiety is the tendency of an individual to perceive environmental stimuli such as different events and situations as threatening; it's stable and reflects how an individual generally feels.
- Conditions
- Anxiety Disorders, Oral Disease, Periodontal Diseases, Periodontal Attachment Loss
- Trial name
- NCT04274855
- Where
- Egypt
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Gingival Recession, Gingival Diseases
Influence of Anatomical Factors Upon Root Coverage
Introduction: Gingival recession is a lesion characterized by the loss of attachment of root surface of the tooth, resulting in an apical migration of the gingival margin that occasionally generates aesthetic problems…
- Conditions
- Gingival Recession, Gingival Diseases, Periodontal Attachment Loss
- Trial name
- NCT04813302
- Testing
- Coronally advanced flap and connective tissue graft
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Periodontitis, Periodontal Diseases
Non-Incised Papillae Surgical Approach (NIPSA) With and Without Graft
This study compared the clinical outcomes of the non-incised papila surgical approach (NIPSA) alone and with grafting biomaterial.
- Conditions
- Periodontitis, Periodontal Diseases, Periodontal Pocket, Periodontal Attachment Loss
- Trial name
- NIPSAGRAFT (NCT04712630)
- Testing
- Non-incised papila surgical approach without grafting biomaterial, Non-incised papila surgical approach with grafting biomaterial
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Universidad de Murcia
Periodontal Attachment Loss, Periodontal Diseases
Safety and Efficacy of Periodontal Surgery in Supra-alveolar-type Defects With or Without Straumann® Emdogain
The primary objective of this study is to demonstrate that in supra-alveolar-type defects (i.e., defects displaying a predominately horizontal pattern of bone loss), periodontal surgery with the additional use of Straumann®…
- Trial name
- NCT01614925
- Testing
- Emdogain, Periodontal surgery
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Institut Straumann AG
Attachment Loss, Periodontal, Teeth, Impacted
Verify if Amelogenins Had Some Benefits in Improving Lower 2nd Molar Periodontal Healing After 3rd Molar Extraction
Background: Prevention of periodontal defects after the extraction of lower third molars remains a challenge. Various methods have been proposed in the literature, but there are no studies which evaluated the effectiveness of…
- Trial name
- NCT04314726
- Testing
- Amelogenin
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Periodontal Attachment Loss, Periodontal Bone Loss
Platelet-Rich Fibrin and Anorganic Bovine Bone vs Collagen Membrane and Anorganic Bovine Bone in Intrabony Defects
The primary outcome of periodontal reconstructive therapy is to regenerate all tissues of the periodontium including a functional periodontal ligament, alveolar bone and cementum.
- Conditions
- Periodontal Attachment Loss, Periodontal Bone Loss, Periodontal Diseases
- Trial name
- NCT03715374
- Testing
- Periodontal Surgery with PRF+ABB, Periodontal Surgery with Collagen Membrane +ABB
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Alveolar Bone Loss, Periodontal Attachment Loss
Bone Height and Extractions Study
A coronectomy is often chosen over complete extraction of a lower third molar when the tooth appears to be in close proximity to the inferior dental (ID) canal, as assessed on a plain radiograph or a cone beam computer tomograph…
- Conditions
- Alveolar Bone Loss, Periodontal Attachment Loss, Periodontal Pocket
- Trial name
- NCT03909568
- Testing
- Third molar surgery
- Volunteers
- 50 people
- Sponsor
- King's College London
Chronic Periodontitis, Periodontal Pocket
Autologous Fibrin Glue Application as an Adjunct to Nonsurgical Periodontal Treatment of Chronic Periodontitis
Chronic periodontitis is an inflammatory and polymicrobic disease characterized by the irreversible loss of alveolar bone and connective tissue attachment of the teeth.
- Conditions
- Chronic Periodontitis, Periodontal Pocket, Periodontal Attachment Loss, Periodontal Diseases
- Trial name
- NCT04082949
- Testing
- autologous fibrin glue application as an adjunct to nonsurgical periodontal treatment of chronic periodontitis
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Inonu University
Periodontal Attachment Loss, Periodontal Pocket
Flavonoid Intake and Periodontal Healing
Periodontitis is a chronic inflammatory disease that, if untreated, will lead to tooth loss. To treat periodontal disease, sanative therapy is used as a first line cost-effective strategy to manage periodontal disease and thus…
- Trial name
- NCT03073161
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Brock University
Cleft Lip and Palate, Periodontal Pocket
Periodontal Changes Following Mid Maxillary Distraction
To evaluate the health status of the periodontium and dentition at the distraction osteogenesis site in CLP subjects using mid maxillary distraction (MMD).
- Conditions
- Cleft Lip and Palate, Periodontal Pocket, Attachment Loss, Periodontal
- Trial name
- NCT03686761
- Testing
- A Involvement with the osteotomy site of the surgery
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alexandria