Clinical trials: Periodontal Bone Loss
Bone Loss, Vertical Alveolar Bone Loss
Bioactive Glass (Sol-gel) for Alveolar Bone Regeneration After Surgical Extraction
The purpose of the present research is to evaluate the effect of bioactive glass in bone regeneration immediately following extraction of mandibular and maxillary premolars.The hypothesis of the study assumes that this treatment…
- Conditions
- Bone Loss, Vertical Alveolar Bone Loss, Horizontal Alveolar Bone Loss
- Trial name
- NCT01878084
- Testing
- bioactive glass (sol-gel), empty extraction socket
- Where
- Egypt
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Alveolar Process Atrophy
Evaluation of a Combined Ridge Expansion Technique With Simultaneous Dental Implant Placement
Patients with long span, narrow edentulous ridge in the posterior mandible underwent piezotomed ridge splitting and osseodensification with simultaneous implant placement.
- Trial name
- NCT05685576
- Testing
- Piezotomed ridge splitting and osseodensification
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Lydia Nabil
Tooth Loss, Partial-edentulism
Retrospective Evaluation of a Novel Biomimetic Synthetic Bone Substitute (Creos® Syntogain)
Guided bone regeneration (GBR) is a commonly performed technique, using autogenous grafts, allografts, xenografts, or synthetic bone grafts (SBG).
- Conditions
- Tooth Loss, Partial-edentulism, Tooth Fracture, Edentulous Alveolar Ridge
- Trial name
- NCT06473545
- Where
- 2 sites in Spain
- Volunteers
- 173 people
- Sponsor
- International dentistry Research Group
Alveolar Bone Loss, Dental Implant
Socket Preservation - A Randomized Clinical Implementation in a Student Setting
Preserving the ridge dimension after tooth extraction aims to avoid the need for bone augmentation procedures before implant placement.
- Conditions
- Alveolar Bone Loss, Dental Implant, Bone Augmentation
- Trial name
- NCT06539299
- Testing
- Socket Preservation
- Volunteers
- 51 people
- Sponsor
- Sigmund Freud PrivatUniversitat
Alveolar Bone Loss, Alveolar Ridge Augmentation
A Novel Approach for Horizontal Augmentation: A Split Box
The goal of this clinical study is to investigate the effectiveness of the split-box technique in systemically healthy, non-smoking, over 18 years of age, participants with narrow crests (<5mm bone width) and adequate bone height…
- Conditions
- Alveolar Bone Loss, Alveolar Ridge Augmentation, Augmentation, Alveolar Ridge
- Trial name
- NCT06177899
- Testing
- Splitting of bone and fixation of bone laminae differ between the 3 groups.
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Marmara University
Alveolar Bone Loss, Chronic Periodontitis, Lovestatin Gel, Regeneration
The Effect of Lovastatin Gel in the Treatment of Chronic Periodontitis
Aim: dis double-blind split-mouth clinical trial study was performed to evaluate teh clinical and radiographic effect of local delivery of lovastatin gel as an adjunct to scaling and root planning (SRP) in teh treatment of…
- Trial name
- NCT03178526
- Testing
- Lovastatin gel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Alveolar Bone Loss
The Influence of Cortical Bone Perforation on Guided Bone Regeneration in Humans
The purpose of this randomized clinical trial was to evaluate the effect of cortical bone decortication on the angiogenesis and osteogenesis of augmented ridge by GBR.
- Trial name
- NCT02741752
- Testing
- Decortication
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Bone Atrophy, Alveolar
Conventional and Ultrasonic Implant Site Preparation
multi center study with randomized controlled trial design, split mouth
- Trial name
- PI-DRI (NCT03357406)
- Testing
- ultrasound implant site preparation, conventional implant site preparation
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Alveolar Bone Loss, Bone Graft; Complications
Patient Satisfaction and Bone Gain Following Autogenous Particulate Sticky Bone Preparation With Xenograft Versus Without Xenograft for Grafting of Maxillary Anterior Knife Edge Ridge in Partially Edentulous Patients for Implant Placement
The aim is to evaluate the value and efficiency of sticky bone in the augmentation of alveolar ridge deficiency when being used with or without xenogenic bone graft for esthetic implant placement.
- Trial name
- NCT03556111
- Testing
- Sticky bone augmentation
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dehiscence, Tooth Extraction
Effect of Collagen Membrane on Ridge Preservation
This study will evaluate whether adding a resorbable collagen membrane to an anorganic bone-collagen composite (ABCC) graft improves ridge preservation after tooth extraction.
- Conditions
- Dehiscence, Tooth Extraction, Alveolar Bone Loss
- Trial name
- NCT07580495
- Testing
- Minimally Invasive tooth extraction, Alveolar ridge preservation with ABCC, Resorbable collagen membrane (InterCollagen® Guide)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Debora Dias
Bone Loss in Jaw
Evaluation of Melatonin and Metformin Loaded Nanoparticles in the Treatment of Periodontal Intra-bony Defects
The goal of this clinical trial is to assess the effectiveness of local delivery of melatonin and metformin loaded nanoparticle gel as adjunct to scaling and root planning (SRP) in the treatment of periodontal intra bony defect.
- Trial name
- NCT05906563
- Testing
- Melatonin gel, Metformin and melatonin gel, scaling and root planning
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Amira ragab
Tooth Loss
Treatment of Post-Extraction Dehisced Socket - A Case Series Study
PURPOSE The purpose of this case series is to clinically, radiographically and histologically evaluate the treatment of dehiscence defects in extraction sockets using a minimally-invasive GBR technique that involves the…
- Trial name
- OSTEO2 (NCT02980211)
- Testing
- Alveolar Ridge Reconstruction
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Gustavo Avila-Ortiz DDS, MS, PhD
Alveolar Bone Loss
Histological Evaluation of Healing Following Ridge Preservation Using a Combined Cortical/Cancellous Mineralized Freeze-Dried Bone Allograft
The study is a 3-arm, parallel-design, randomized, prospective clinical trial.designed to examine histologic wound healing following ridge preservation using cortical bone allograft, cancellous bone allograft, or a combination of…
- Trial name
- NCT02275767
- Testing
- 50% cortical/50% cancellous FDBA, 100% cortical FDBA, 100% cancellous FDBA
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Alveolar Bone Loss
Comparison Synthetic Hydroxyapatite and Inorganic Bovine Bone in Sinus Floor Elevation
This is set as prospective clinical trial to correlate histologically and radiologically the performance of four different bone grafts (synthetic hydroxyapatite alone, synthetic hydroxyapatite mixed with polylactic-polyglycolic…
- Trial name
- SYNBIO (NCT03077867)
- Testing
- sinus floor augmentation with bone graft
- Where
- Italy
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Alveolar Bone Loss
Alveolar Ridge Preservation (ARP) in the Posterior Maxilla After the Extraction of Maxillary Molars
Dental implants are a fixed replacement solution with reported long-term survival rates between 94-98% over 20-40 years. In order to ensure successful implant therapy, adequate bone and soft tissue as well as correct 3D…
- Trial name
- NCT07433322
- Testing
- Ossix mineralized grafting immediately at extraction, Delayed grafting at implant placement
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Virginia Commonwealth University
Alveolar Bone Loss
Treatment of Alveolar Bone Defects Using Aastrom Biosciences Autologous Tissue Repair Cell Therapy
The purpose of this research is to determine if a subject's own bone marrow tissue can help regenerate bone in the area of his/her jaw where a tooth has been removed using Tissue Repair Cell (TRC) Therapy.
- Trial name
- NCT00755911
- Testing
- Tissue Repair Cells (TRC), Control
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Michigan
Alveolar Bone Loss
Clinical, Radiographical, Histological Evaluation and Blood Flow Analysis of Alveolar Ridge Preservation
With alveolar ridge preservation (ARP) ridge resorption following extraction may be reduced. Several materials and techniques have been advocated for ARP.
- Trial name
- NCT05674331
- Testing
- Extraction site development technique, autogenous tooth bone graft, Socket seal technique
- Where
- Hungary
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Moderate to Advanced Chronic Periodontitis
Local Minocycline to Reduce Future Inflammation and Bone Loss in Periodontal Maintenance Patients
The purpose of this study is to determine the effect of local application of minocycline microspheres on the periodontal inflammation and bone loss prevention in patients diagnosed with moderate-severe chronic periodontitis…
- Trial name
- NCT01647282
- Testing
- locally-applied minocycline HCl (1 mg), scaling and root planing (Sc/RP)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Nebraska
Tooth Loss, Surface Treatment
Effect of Different Loading Protocols on Photofunctionalized Implants in the Posterior Maxilla
This randomized clinical trial evaluates different loading protocols for UV-photofunctionalized dental implants in the posterior maxilla. Clinical and radiographic outcomes will be assessed during follow
- Conditions
- Tooth Loss, Surface Treatment, Immediate Dental Implant Loading, Implant Loading
- Trial name
- PHOTOLOAD (NCT07700914)
- Testing
- Immediate loading of UV-photofunctionalized dental implants, Early loading of UV-photofunctionalized dental implants, Conventional loading of UV-photofunctionalized dental implants
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Tooth Loss, Alveolar Ridge Resorption After Extraction
BMP Effect on Implant Stability and Marginal Bone Level After Immediate Placement
This randomized controlled clinical trial aims to evaluate the effect of recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) on the stability and marginal bone level of dental implants following immediate placement.
- Conditions
- Tooth Loss, Alveolar Ridge Resorption After Extraction, Tooth Extraction
- Trial name
- NCT07240493
- Testing
- rhBMP-2 placement, conventional immediate implant
- Where
- Iraq
- Volunteers
- 24 people
- Sponsor
- Aya Adil Saeed