Clinical trials: Periodontal Disease : Chronic Periodontitis
- Condition Periodontal Disease : Chronic Periodontitis
- Funder type Industry (pharma, biotech, devices)
Adult Periodontitis
Periocline as an Adjunct to Scaling and Root Planing for Adult Periodontitis
Periodontal disease (commonly called gum disease) is generally treated by deep cleaning of the root surfaces of the teeth. This is also called scaling and root planing.
- Trial name
- NCT00529555
- Testing
- minocycline HCl 2.1%, Scaling and root planing
- Where
- 10 sites in United States
- Volunteers
- 602 people
- Sponsor
- Sunstar Americas
Periodontitis
Long-term Safety of Minocycline in Patients With Gum Disease
This study will look at the safety of using the study medicine for a long time. It will see if the germs get used to the medicine, making it not work as well, if it's used by people with gum disease for a long time.
- Trial name
- NCT00668746
- Testing
- Minocycline HCl microspheres
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- OraPharma
Chronic Periodontitis
Efficacy of a Probiotic Lozenge (Inersan) in Patients With Chronic Periodontitis
Periodontal disease is a major cause of tooth loss in humans and is one of the most prevalent diseases associated with bone loss.
- Trial name
- NCT01870362
- Testing
- Probiotic (Inersan)
- Where
- India
- Volunteers
- 28 people
- Sponsor
- CD Pharma India Pvt. Ltd.
Chronic Periodontitis
Efficacy and Safety of a Commercially Available Injectable Hyaluronic Acid Dental Filler for Periodontal Pockets
This is a controlled, randomized, single-blinded, multicenter, prospective clinical study. In addition to the standard periodontal treatment procedure on all teeth that need to be treated, the 4 teeth with the deepest pockets…
- Trial name
- NCT02391974
- Testing
- PERIOSYAL FILL
- Where
- 3 sites in Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Chronic Periodontitis
Effect of Probiotic Inersan and Doxycycline in Chronic Periodontitis
Periodontitis is a multifactorial disease that can lead to the destruction of supporting tissues of the teeth resulting in pocket formation, recession or both.
- Trial name
- NCT02174757
- Testing
- Inersan, Doxycycline
- Where
- India
- Volunteers
- 30 people
- Sponsor
- CD Pharma India Pvt. Ltd.
Periodontitis
The Efficacy and Safety of PerioChip Plus (Flurbiprofen/Chlorhexidine) Formulation in the Therapy of Adult Periodontitis
The purpose of this study is to determine the effect of the placement of a PerioChip Plus (flurbiprofen/chlorhexidine - FBP/CHX) formulation versus PerioChip (chlorhexidine) formulation versus Flurbiprofen Chip formulation versus…
- Trial name
- NCT00425451
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Dexcel Pharma Technologies Ltd.
Chronic Periodontitis
A Clinical Trial of YH14642 in Patients With Chronic Periodontal Disease
This study is designed to evaluate the efficacy and the safety of YH14642 in Korea patients with chronic periodontitis, in order to investigate the recommended therapeutic dose.
- Trial name
- YH14642 (NCT01499225)
- Testing
- YH14642 500mg Tab, INSADOL[Zea mays L. extract] 35mg Tab, DENTISTA[Doxycycline hyclate] 20mg Cap
- Where
- South Korea
- Volunteers
- 162 people
- Sponsor
- Yuhan Corporation
Periodontitis Chronic Generalized Moderate, Periodontitis Chronic Generalized Severe
Regular Home-use of Dual-light Photodynamic Therapy in the Management of Chronic Stage III-IV Periodontitis
This study is designed to determine the efficacy of the Lumoral method in chronic periodontitis with a targeted group of stage III and IV periodontitis.
- Trial name
- NCT05698823
- Testing
- Lumoral Treatment
- Where
- Lithuania
- Volunteers
- 56 people
- Sponsor
- Koite Health Oy
Periodontitis
The Efficacy and Safety of Flurbiprofen Chip Versus Chlorhexidine Chip (Periochip®) in Therapy of Adult Chronic Periodontitis
The purpose of the study is to assess efficacy and safety of Flurbiprofen Chip versus Chlorhexidine chip (Periochip®) in therapy of adult chronic periodontitis.
- Trial name
- NCT01040286
- Testing
- Flurbiprofen, Chlorhexidine
- Where
- Israel
- Sponsor
- Dexcel Pharma Technologies Ltd.
Chronic Periodontitis
A Phase II Clinical Trial of YH23537 in Patients With Chronic Periodontal Disease.
This study is designed to evaluate the efficacy and the safety of YH23537 in Korea patients with chronic periodontitis, in order to investigate the recommended therapeutic dose.
- Trial name
- NCT02585596
- Testing
- YH23537 1000mg/day, YH23537 2000mg/day, YH23537 3000mg/day
- Where
- South Korea
- Volunteers
- 275 people
- Sponsor
- Yuhan Corporation
Probiotics, Periodontitis
Efficacy of Supplementation With Probiotics as Adjuvant to Mechanical Treatment in Chronic Periodontitis
It aims to demonstrate the superiority of a 6-week supplementation with Lactibiane Buccodental compared to placebo, as adjunctive therapy in chronic periodontitis in patients with generalized chronic periodontitis
- Trial name
- NCT03554187
- Testing
- Ultrasonic periodontal Debridement, with appropriate device, Analyzes of periodontopathogenic bacteria, IL1B test
- Where
- 2 sites in France
- Volunteers
- 51 people
- Sponsor
- PiLeJe
Periodontitis
Effect of Adjunctive Treatment With Arestin on the Subgingival Microflora in Patients With Moderate to Advanced Periodontitis
The purpose of this study is to measure the antimicrobial effects of Arestin in subjects with moderate to advanced periodontal disease
- Trial name
- NCT00371332
- Testing
- Minocycline HCL Microspheres
- Where
- 5 sites in United States
- Volunteers
- 128 people
- Sponsor
- OraPharma
Periodontitis
SRP in Combination With PERIOWAVE in Comparison to SRP Alone in Chronic Periodontitis
This study is to determine whether scaling and root planning (SRP) followed by photodynamic disinfection results in improved outcomes that persist over time in adults with chronic periodontitis when compared with subjects with…
- Trial name
- NCT00296881
- Testing
- PERIOWAVE
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Ondine Research Laboratories
Chronic Periodontitis
Perio. Maint. With Diode LBR
The primary aim of this pilot study is to determine whether the test methods described feasibly achieve the goal defined for a future clinical study.
- Trial name
- NCT05276817
- Testing
- Epic Diode, HP
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Biolase Inc
Periodontitis
Study of Scaling and Root Planing (SRP) With PerioWave vs. SRP Alone in Chronic Periodontitis
This study is to determine whether scaling and root planning (SRP) followed by photodynamic disinfection results in improved outcomes that persist over time in adults with chronic periodontitis when compared with subjects with…
- Trial name
- NCT00297518
- Testing
- PerioWave, Scaling and Root Planing
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Ondine Research Laboratories
Chronic Periodontitis
IgY Efficacy on Periodontitis Patients
Patients visiting National Hospital of Odonto-Stomatology for treating periodontitis used a food supplement (lozenge) containing chicken egg antibody (IgY) against Porphyromonas gingivalis gingipains as an adjunct to conventional…
- Trial name
- NCT02705885
- Testing
- lozenges containing IgY
- Volunteers
- 60 people
- Sponsor
- Immunology Research Institute in Gifu
Chronic Periodontitis
Efficacy of a Probiotic Lozenges in Chronic Periodontitis Patients.
Periodontal disease is an infectious disease resulting in inflammation within supporting tissues of the teeth, progressive attachment loss, and bone loss.
- Trial name
- NCT02121665
- Testing
- Probiotic (Inersan)
- Where
- India
- Volunteers
- 42 people
- Sponsor
- CD Pharma India Pvt. Ltd.
Chronic Periodontitis
Clinical Trial of PeriZone PerioPatch in Subjects With Chronic Periodontitis
The purpose of this study is to determine if a topical, adhesive patch (PeriZone PerioPatch) applied to the gums after a deep tooth cleaning (scaling and root planing) reduces the signs of advanced gum disease (chronic…
- Trial name
- NCT01808703
- Testing
- PeriZone PerioPatch, Scaling and root planing alone
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- MIS Implant Technologies, Ltd
Periodontal Diseases, Chronic Periodontitis
Effect of Switching From Cigarette Smoking to the Use of IQOS on Periodontitis Treatment Outcome
The purpose of this study was to demonstrate in patients with generalized chronic periodontitis that switching from cigarette smoking to using IQOS improves the response to periodontal therapy and the overall oral health status…
- Conditions
- Periodontal Diseases, Chronic Periodontitis, Periodontal Pocket, Tooth Mobility
- Trial name
- NCT03364751
- Testing
- IQOS, Cigarette
- Where
- 26 sites in Japan
- Volunteers
- 179 people
- Sponsor
- Philip Morris Products S.A.
Periodontitis
Regular Home Use of Dual-light Photodynamic Therapy in the Management of Chronic Periodontitis
The study is a single site, randomized clinical trial designed to determine the efficacy of the Lumoral treatment in periodontitis patients.
- Trial name
- HOPE-CP (NCT05278416)
- Testing
- Lumoral treatment -device and Lumorinse tablets
- Where
- Finland
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Koite Health Oy