Clinical trials: Periodontal Health
- Condition Periodontal Health
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Dental Plaque, Gingivitis
A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
The aim of this study is to assess the ability of a marketed Cetylpyridinium Chloride (CPC) mouthwash alongside a marketed Stannous Fluoride (SnF2) toothpaste in improving gingival health and reducing plaque accumulation…
- Trial name
- NCT06660069
- Testing
- Stannous Fluoride Toothpaste (Parodontax Complete Protection Toothpaste), CPC Mouthwash (Parodontax Active Gum Health Mouthwash), Regular Fluoride Toothpaste (Crest Cavity Protection)
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- HALEON
Plaque, Gingivitis
Determination of the Safety and Efficacy of a Novel Oral Rinse on Oral Health
Since over 50% of the US population have gingivitis, mouthrinses serve as a valuable adjunct to brushing and flossing. The primary objective is to determine the effectiveness of the oral rinse in reducing plaque and gingivitis…
- Trial name
- NCT04197427
- Testing
- Experimental Oral Rinse
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- You First Services
Dental Plaque, Gingivitis
A Study to Investigate the Efficacy of an Experimental Dentifrice Containing Stannous Fluoride in Improving Gingival Health
The aim of this study will be to evaluate the ability of using an experimental dentifrice containing 0.454 percent (%) weight for weight (w/w) Stannous Fluoride (SnF2) to reduce gingivitis and plaque accumulation, compared with a…
- Trial name
- NCT07704905
- Testing
- Test Dentifrice, Reference Dentifrice (Colgate Cavity Protection Dentifrice)
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- HALEON
Gingivitis, Periodontal Disease
Rapid Point-of-Care Salivary Diagnostic for Periodontal Health
The purpose of this study is to learn if a chair-side testing device will accurately measure levels of a salivary biomarker and thus indicate if a patient has periodontal health, gingivitis or periodontal disease.
- Trial name
- NCT02403297
- Testing
- Quik Check PD
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Innovative Diagnostics Inc
Periodontal Diseases
Effect of TCI188 Probiotic on Oral Health
To assess the efficacy of TCI188 (Pediococcus acidilactici) Probiotic on Oral Health
- Trial name
- NCT06141083
- Testing
- TCI188 Probiotic
- Where
- Taiwan
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Gingival Inflammation, Dental Plaque
A Study to Measure the Effect of a Toothpaste Containing Proteins and Enzymes and a Fluoride Toothpaste on Gingival Health
This study is a double-blind, randomised, parallel group efficacy study. A minimum of 240 healthy female and male participants aged 18-70 years will be enrolled onto the study according to the inclusion/exclusion criteria.
- Trial name
- NCT06932211
- Testing
- Toothpaste containing proteins and enzymes, Control fluoride toothpaste
- Where
- China
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Oral Health Related Quality of Life (OHRQoL)
New Functional Ingredient for Oral Care
The goal of this clinical trial is to find new ingredients for oral care products that can improve gum health. We want to learn if new botanical blends can help reduce gum inflammation, strengthen the gum's natural barrier, and…
- Trial name
- NCT07771907
- Testing
- Botanical A, Botanical B
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Access Business Group
Gingivitis
Efficacy of the Addition of a Power Interdental Device to an Electric Toothbrush on Gingival Health.
The study is designed to evaluate the clinical changes in gingival health by measuring the reduction of gingival bleeding and inflammation over 4 weeks.
- Trial name
- NCT04003298
- Testing
- Electric toothbrush, Control
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Water Pik, Inc.
Dental Plaque, Gingivitis
A Clinical Study to Evaluate the Effectiveness of an Experimental Toothpaste in Improving Gum Health and Reducing Plaque Accumulation
The aim of this 24-week clinical study is to evaluate the ability of an experimental dentifrice containing 0.454 percent (%) weight by weight (w/w) Stannous fluoride (SnF2); to improve gingival health, plaque reduction and…
- Trial name
- NCT07255040
- Testing
- Test Dentifrice, Parodontax Complete Protection, Colgate Cavity Protection
- Where
- United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- HALEON
Gingival Inflammation, Gingival Bleeding
Evaluation of a Toothpaste Containing a Gum Health Active in Participants With Gingival Problem
The primary objective of this clinical study is to evaluate the impact on gingival health when participants switch to a fluoride toothpaste without gum-health actives for 4 weeks after using a proven gum-health toothpaste for 13…
- Conditions
- Gingival Inflammation, Gingival Bleeding, Dental Plaque
- Trial name
- NCT07415733
- Testing
- Test Toothpaste, Control Toothpaste
- Where
- Indonesia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Gingivitis
A Follow-Up Survey of Oral Hygiene and Health Outcomes for Women Previously Enrolled in "OHMOM"
The objective of this study is to assess oral health, oral hygiene knowledge, and daily oral hygiene practices of women who participated in a randomized controlled trial (2011001) at University of Alabama Birmingham during the…
- Trial name
- OHBABY (NCT02922010)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Periodontitis
Effectiveness of a Triclosan Containing Toothpaste in Maintaining Periodontal Health in a Type 2 Diabetic Population
Clinical research study to determine the effectiveness of a triclosan/copolymer/fluoride toothpaste in maintaining periodontal health and therefore glycaemic control in a type 2 diabetic population.
- Trial name
- NCT00762762
- Testing
- Triclosan/copolymer/fluoride, Fluoride
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingival Diseases
A Study to Measure the Effect of Two Fluoride Toothpastes on Gingival Health Over a Six Month Period
This study is a double-blind, randomised, parallel group efficacy study. A minimum of 240 healthy female and male participants aged over 18 years will participate. The participants will be randomised into two groups.
- Trial name
- NCT03027908
- Testing
- Fluoride Toothpaste 1, Fluoride Toothpaste 2
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Oral Health
Evaluation of a Daily Oral Care Lozenge on Oral Health and Quality of Life in Older Adults
The assessment of a daily oral care lozenge (PTx800) will be compared to a placebo control in a cohort of older adults who visit adult senior centers and who also have mild to moderate gingivitis.
- Trial name
- NCT03693027
- Testing
- PTx800 lozenges
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Primal Therapies Inc.
Gingivitis, Dental Plaque Accumulation
6-month Clinical Investigation Assessing the Efficacy of an Antimicrobial Mouthrinse in Reducing Established Plaque and Improving Gum Health
The goal of this clinical trial is to evaluate the clinical efficacy of an antimicrobial mouthrinse, with a particular focus on its effect on established plaque and the improvement of gum health.
- Trial name
- NCT07414173
- Testing
- Test Mouthrinse, Control Mouthrinse
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis
Powered Toothbrush Versus Manual Toothbrush on Plaque and Gingivitis After a Six-Week Period of Home Use
The goal of this clinical trial is to learn if powered toothbrushing is more effective than manual toothbrushing in removing dental plaque. It will also learn about the safety of power toothbrushing.
- Trial name
- NCT07691814
- Testing
- power toothbrush, manual toothbrush
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Gingivitis, Dental Plaque
A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health
The aim of this analysis was to compare gingivitis- and plaque-reduction efficacy from randomized controlled trials (RCTs) up to six months long evaluating oscillating-rotating, sonic, and manual toothbrushes
- Trial name
- NCT05594004
- Testing
- Oscillating-rotating electric toothbrush, Sonic electric toothbrush, Manual toothbrush
- Where
- United States
- Volunteers
- 2,929 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Gingivitis
Efficacy of SALI-10 Oral Probiotics in Experimental Gingivitis
Gingivitis is among the most prevalent oral diseases worldwide, affecting an estimated 50-90% of adults. It is a reversible condition primarily caused by microbial plaque accumulation on teeth and gingival surfaces, which…
- Trial name
- NCT07256743
- Testing
- SALI-10 lozenge
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ostia Sciences
Gingivitis
A Phase 3 Clinical Study Investigating the Gingivitis Efficacy of a Test Dentifrice Containing Stannous Fluoride
The purpose of this study is to evaluate and compare the gingival health of a test dentifrice (0.454% weight by weight [w/w] stannous fluoride) to a negative control dentifrice by comparing modified gingival index, bleeding index…
- Trial name
- NCT04123665
- Testing
- Stannous fluoride, Sodium monofluorophosphate
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Gingivitis
Meta-analysis of Stannous Fluoride and the Effects on Gingival Health
The aim of this 18 study analysis was to compare the effect of bioavailable stannous fluoride (SnF2) dentifrices when used up to 3 months on gingivitis relative to a positive or negative control dentifrice.
- Trial name
- NCT03970759
- Testing
- Stannous Fluoride Dentifrice, Positive control dentifrice, Negative control dentifrice
- Where
- United States
- Volunteers
- 2,890 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble