Clinical trials: Periodontal Health
Mandibular Distal-extension Prostheses
Periodontal Health and Patient Satisfaction of CAD/CAM Fiber-Reinforced vs. PFM Attachments in Distal Extension RPDs
This randomized clinical trial aims to assess periodontal health and patient satisfaction in mandibular distal extension removable partial dentures using CAD/CAM fiber-reinforced composite versus porcelain-fused-to-metal…
- Trial name
- NCT06871020
- Testing
- Mandibular removable partial denture retained on OT extracoronal attachment made from fiber-reinforced composite resin, Mandibular removable partial denture retained on OT extracoronal attachment made from porcelain-fused to metal
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Tobacco Use, Periodontitis
Snuff Use, Smoking, Periodontal Health and Premature Death: 30-year Study
Snuff use and smoking associated with poor periodontal health, especially if used together.
- Trial name
- NCT03614871
- Testing
- Epidemiological study
- Volunteers
- 1,676 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Periodontitis, Healthy
Effect Of Scaling and Root Planning on ALP in Saliva and GCF In Periodontitis Patients Compared With Healthy Individuals
The goal of this [interventional clinical trial] is to test effect of scaling and root plaining on Alkaline phosphatase in Saliva and Gingival crevicular fluid in periodontitis patients compared with healthy subjects The…
- Trial name
- NCT06048016
- Testing
- Scaling and Root Planning
- Where
- Egypt
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Cairo University
COPD Exacerbation, Periodontal Health
Efficacy of Periodontal Treatment on Systemic Inflammation and for Prevention of Exacerbations in Patients With COPD
Current data are showing a potential link between inflammatory biomarkers in chronic periodontitis and COPD. However the impact of periodontal treatment on systemic inflammation as measured by biomarkers and time to occurrence of…
- Trial name
- Expertention (NCT03279718)
- Testing
- Periodontal Treatment
- Where
- 3 sites in Germany
- Volunteers
- 4 people
- Sponsor
- Heidelberg University
Periodontal Disease
Power Toothbrush Use in Nursing Homes to Eliminate Mouth and Body Inflammation
The purpose of this study is to investigate whether brushing the teeth of nursing home residents with a power toothbrush as compared with standard care typically provided in nursing homes, will increase caregiver compliance with…
- Trial name
- NCT01639183
- Testing
- Rotating-oscillating Power Toothbrush, Standard Care
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Smoking ( Cigarette), Smoking (Tobacco) Addiction
Smoking Cessation With Wearables to Improve General, Oral Health and Quality of Life
Tobacco smoking remains one of the leading preventable causes of disease, disability, and premature death worldwide. According to the World Health Organization, tobacco use is responsible for more than eight million deaths each…
- Conditions
- Smoking ( Cigarette), Smoking (Tobacco) Addiction, Smoking Behaviors, Smoking Cessation
- Trial name
- Wear-Smile (NCT07593742)
- Testing
- Telemedicine-Based Smoking Cessation Program, Conventional Smoking Cessation Behavioral Program
- Volunteers
- 102 people
- Sponsor
- University of Salerno
Black Stains
Assessment of Black Stains on Teeth in Relation to Salivary Parameters, Periodontal Health, and Body Mass Index in Children
Objective The aim of this study is to compare salivary flow rate, salivary pH, salivary buffering capacity, plaque index, gingival index, DMFT/dft indices, and body mass index (BMI) in systemically healthy children aged 5-10…
- Trial name
- NCT06985446
- Testing
- Study Group:Black stain-positive, Control Group: Black stain-negative
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Gingivitis, Oral Disease
Metagenome Resilience in Experimental Gingivitis
This study aims to identify new biomarkers that indicate the resilience of individuals to developing oral disease. An 'experimental gingivitis' model will be employed in which subjects will refrain from oral hygiene in one…
- Trial name
- NCT05389124
- Testing
- Partial abstinence from oral hygiene
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Periodontitis, Adult
Early Versus Delayed Orthodontic Treatment After Periodontal Surgery on Periodontal Health in Periodontally Compromised Patients
RESEARCH QUESTION: Will there be a difference in periodontal health of two groups of periodontally compromised orthodontic patients with early and delayed start of orthodontic treatment after periodontal surgery? Population…
- Trial name
- NCT05466253
- Testing
- Fixed Orthodontic treatment
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Acne Vulgaris, Gingivitis and Periodontal Diseases
Retinoic Acid Therapy and Regulation of Salivary and Serum IL-1β, IL-8 and MCP-1 Levels
This prospective cohort study analysed the effects of systemic retinoic acid use on periodontal status, salivary flow rate (SFR), and salivary and serum levels of interleukin (IL)-1β, IL-8 and monocyte chemoattractant protein…
- Conditions
- Acne Vulgaris, Gingivitis and Periodontal Diseases, Saliva Collection, Inflammation Biomarkers
- Trial name
- NCT06879795
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medipol University
Gingivitis
Health Impact of L.Reuteri Consumption in Crew Members of a Naval Ship at Sea
This study is designed to evaluate the impact of the regular consumption of probiotic Lactobacillus reuteri-containing lozenges over a period of 42 days on parameters of oral and general health in crew members of a naval ship at…
- Trial name
- NAVLAC16 (NCT02775019)
- Testing
- Lactobacillus reuteri
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Epilepsy, Gingivitis
Air Polishing Effect on Biological, Clinical and Patient-reported Experience Among Epileptic and Non-epileptic Children
In epileptic and non Epileptic children, the full dentition of each patient was split into four quadrants, starting from the upper right quadrant (1) and moving clockwise until the lower right quadrant (4).
- Trial name
- NCT06144034
- Testing
- Air polishing with erythritol powder, Conventional treatment
- Where
- 2 sites in Jordan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Periodontitis, Diagnosis
Self-detection and Professional Screening Strategies for Early Detection of Periodontal Disease
The majority of the burden of periodontal diseases in the population remain undetected. Self-detection and confirmation with simple, non-clinical tests may improve early case detection and access to the needed level of care.
- Conditions
- Periodontitis, Diagnosis, Self-Assessment
- Trial name
- NCT05513599
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Dental Caries, Gingivitis
Shifts in the Oral Biofilm of Patients With Known Oral Health Risk Factors
This study is observational only and is intended to evaluate changes in the makeup and function of bacteria naturally present in the mouth during treatment with braces to straighten teeth.
- Trial name
- NCT02885064
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Gingivitis, Periodontal Infection
Intervention Study of Oral Health Education Programs Directed to Adolescents
This study evaluates behavioral interventions to increase adolescent's motivation for self performed periodontal infection control, by means of adequate oral hygiene.
- Trial name
- NCT02906098
- Testing
- Patient centered oral health education, Standard educational intervention
- Where
- Sweden
- Volunteers
- 312 people
- Sponsor
- Göteborg University
Dental Anxiety, Periodontal Health
Dental Anxiety and Periodontal Health
Mothers usually have the primary role in bringing up children and developing health-related behaviors. The aim of this study was to determine the effect of mothers' dental anxiety and oral hygiene on the dental anxiety and…
- Conditions
- Dental Anxiety, Periodontal Health, Oral Hygiene
- Trial name
- NCT05563532
- Testing
- dental anxiety and oral hygiene
- Where
- Turkey (Türkiye)
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Okan University
Periodontal Disease, Obesity & Overweight
Effect of GLP-1 Receptor Agonists on Periodontal Health and Response to Nonsurgical Periodontal Therapy
This study aims to evaluate the effects of glucagon-like peptide-1 receptor agonist (GLP-1 RA) use on periodontal health and the response to non-surgical periodontal therapy in individuals with obesity and periodontitis.
- Trial name
- GLP1-PERIO (NCT07770906)
- Testing
- non-surgical periodontal therapy
- Volunteers
- 40 people
- Sponsor
- Cukurova University
Gingivitis, Plaque Induced Gingivitis
The Effect of Enzyme-containing Mouth Spray on Oral Health Status and S.Mutans Levels in Paediatric Patients
An interventional study was done on evaluating the Effect of Enzyme-containing Mouth Spray on Oral Health Status and S.Mutans levels in Paediatric Patients attending Hospital Universiti Sains Malaysia ( HUSM ) , Kelantan.
- Trial name
- NCT05576610
- Testing
- Standard preventive advice+ enzymatic mouth sprays ( Oral7 mouth spray)
- Where
- Malaysia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hospital Universiti Sains Malaysia
Mental Health Issue, Periodontitis
Association Between Periodontal Status and Mental Health in Postpartum Women
Background- In developing countries like India, seeking mental health care is still a taboo, and a lot of stigma is attached to consulting a psychiatric specialist or a counselor.
- Conditions
- Mental Health Issue, Periodontitis, Periodontal Diseases
- Trial name
- NCT05869981
- Where
- India
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Oral Hygiene, Gingivitis
Impact of 2D:4D Ratio on Oral Hygiene and Gingival Health
The second-to-fourth digit ratio (2D:4D)-the ratio of the length of the index finger to that of the ring finger-has gained increasing attention as a non-invasive, stable biomarker of prenatal sex hormone exposure.
- Trial name
- NCT07147998
- Testing
- Oral hygiene instruction
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Okan University