Clinical trials: Periodontitis, diet or lifestyle or exercise or nutrition or physical activity or counseling, open to volunteers
- Condition Periodontitis
- Drug or intervention diet OR lifestyle OR exercise OR nutrition OR physical activity OR counseling
- Status Open to volunteers
Acute Myocardial Infarction, Severe Periodontitis
Impact of Treating Severe Periodontitis on Inflammatory Activity of Atheromatous Plaques in Patients With Acute Myocardial Infarction (AMI)
Multicenter randomized clinical trial with two arms in patients hospitalized for an AMI nested in the Frenchie registry. Periodontal therapy is performed by periodontists in the intervention group versus treatment by dental…
- Conditions
- Acute Myocardial Infarction, Severe Periodontitis, Carotid Atherosclerosis
- Trial name
- PAROCARD (NCT04046237)
- Testing
- Periodontal treatment
- Where
- France
- Volunteers
- 210 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Motivational Interviewing, Periodontitis
Motivational Interviewing and Subgingival Instrumentation Outcomes in Periodontitis
Motivational Interviewing (MI) represents a patient centered counselling approach designed to facilitate behaviour change by guiding patients through the exploration and resolution of ambivalence toward positive health actions.
- Conditions
- Motivational Interviewing, Periodontitis, Oral Hygiene
- Trial name
- NCT07618533
- Testing
- Motivational Interviewing, Oral hygiene instructions
- Where
- India
- Volunteers
- 66 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Stage II Grade B Periodontitis
Active Oxygen Gel vs Chlorhexidine Gel in Stage II Grade B Periodontitis
This randomized controlled clinical trial will evaluate the effectiveness of locally delivered active oxygen gel and chlorhexidine gel as adjuncts to scaling and root planing in the treatment of stage II grade B…
- Trial name
- NCT07840716
- Testing
- Active oxygen gel, Chlorhexidine gel
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Metabolic Syndrome (MetS), Periodontitis
Metabolic Syndrome Associated Diet
The goal of this observational study is to examine the relationship between metabolic syndrome (MetS) and periodontitis, and to evaluate the role of the Dietary Inflammatory Index (DII) in this association.
- Conditions
- Metabolic Syndrome (MetS), Periodontitis, Diet, Food and Nutrition
- Trial name
- NCT07462104
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Periodontal Diseases, Periodontitis
Evaluation Of The Efficacy Of Subgingival Application Of Lovastatin Gel As An Adjunct To Non-Surgical Treatment Of Periodontitis In Generally Healthy Smokers And Non-Smokers Patients in Central Europe.
The aim of the study is to evaluate how a gel (1.2% lovastatin) applied under the gum improves the results of classic periodontal treatment (SRP-scaling, root planing).
- Conditions
- Periodontal Diseases, Periodontitis, Periodontal Disease, Smokers
- Trial name
- RCT (NCT07282756)
- Testing
- Subgingival application of 1.2% lovastatin
- Where
- Poland
- Volunteers
- 44 people
- Sponsor
- Medical University of Silesia
Preterm Birth, Low Birthweight Neonate
Xylitol and the Prevention of Periodontal Disease and Preterm Birth Trial
The ground-breaking Prevention of Prematurity and Xylitol (PPaX) cluster randomized controlled clinical trial was conducted in Lilongwe, Malawi and enrolled approximately 10,069 pregnant individuals seeking to evaluate the impact…
- Conditions
- Preterm Birth, Low Birthweight Neonate, Periodontitis, Gingivitis
- Trial name
- XaPPP (NCT07424846)
- Testing
- Xylitol Chewing gum, Sorbitol chewing gum
- Where
- Malawi
- Volunteers
- 6,000 people
- Sponsor
- University of Washington
Periodontal Disease, Periodontitis
Periodontal Disease in Rare Renal Disorders (PERIO-RA-RE)
This study aims to evaluate the burden and phenotypic spectrum of periodontal disease in patients with rare kidney disorders (such as Alport syndrome, Fabry disease, and tuberous sclerosis complex) and systemic lupus…
- Conditions
- Periodontal Disease, Periodontitis, CKD, Chronic Kidney Disease
- Trial name
- PERIO-RA-RE (NCT07575347)
- Testing
- Observational assessment
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- Stefan Lujinschi
Periodontitis Stage II
"Comparison of Spirulina Gels for Treating Stage II Grade B Periodontitis"
This randomized controlled clinical study investigates the effectiveness of Spirulina gel and Spirulina nanoparticles gel in treating Stage II Grade B periodontitis.
- Trial name
- NCT06699654
- Testing
- Spirulina Gel, Spirulina Nanoparticles Gel
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Kafrelsheikh University
Periodontitis, Periodontal Disease
Investigation of the Relationship Between Periodontitis and Sleep Quality
This project aims to investigate the relationship between periodontitis and sleep quality. Its originality lies in evaluating the association between periodontal status and sleep quality together with salivary interleukin-6…
- Conditions
- Periodontitis, Periodontal Disease, Sleep Quality, Fatigue
- Trial name
- RBPSQ (NCT07421960)
- Testing
- Periodontal examinations, Collection of saliva samples, Pittsburgh Sleep Quality Index
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Aortic Valve Stenosis, Periodontitis
Intensive Treatment on Periodontitis in Aortic Stenosis
The goal of this clinical trial is to determine if standardized periodontal therapy can effectively slow the progression of aortic valve stenosis in adult patients diagnosed with moderate aortic valve stenosis and coexisting…
- Trial name
- NCT06587971
- Testing
- Standard periodontal treatment protocol, Oral hygiene education
- Where
- China
- Volunteers
- 920 people
- Sponsor
- China National Center for Cardiovascular Diseases
Severe Periodontitis, Ischemic Stroke
Effectiveness of Periodontitis Treatment on the Metabolic Activity of Symptomatic Carotid Atherosclerotic Plaque Responsible for Ischemic Stroke
Cardiovascular disease is the world's leading cause of death. Atherothrombosis is a common cause of ischemic stroke. A strong epidemiological link has been established between periodontitis and the risk of stroke.
- Trial name
- PerioStroke (NCT06484036)
- Testing
- periodontal treatment strategy
- Volunteers
- 157 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Periodontitis, Adult, Periodontitis (Stage 3)
Microbiological and Clinical Effects of Pre- and Probiotics in Non-Surgical Periodontal Therapy
Periodontitis is a prevalent chronic inflammatory disease driven by a dysbiotic oral biofilm and a dysregulated host immune response.
- Conditions
- Periodontitis, Adult, Periodontitis (Stage 3), Periodontitis Stage IV
- Trial name
- PROPARO (NCT07443410)
- Testing
- Non-surgical periodontal therapy (NSPT) and supportive periodontal therapy (SPT), Probiotic lozenge (Limosilactobacillus reuteri; GUM® PerioBalance®), Vitamin B12 drops (natural elements)
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Periapical Periodontitis, Pulpitis
Postoperative Pain Evaluation After Obturation With Different Sealers
This study aims to evaluate the incidence and intensity of postoperative pain in patients undergoing root canal treatment on teeth diagnosed with pulpitis, pulp necrosis, or with previous endodontic treatment.
- Conditions
- Periapical Periodontitis, Pulpitis, Necorsis
- Trial name
- NCT07018284
- Testing
- AH Plus (Dentsply Sirona, Charlotte, NC, USA), NeoSealer Flo, Continuous Wave Condensation
- Where
- Spain
- Volunteers
- 270 people
- Sponsor
- University of Siena
Periodontal Pocket
Ozonized Olive Oil in the Treatment of Periodontal Pockets
A randomized controlled clinical trial was conducted on 16 patients (8 males and 8 women) who were diagnosed chronic periodontitis.
- Trial name
- NCT06980675
- Testing
- Activated Ozonized Olive Oil Gel
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bari
Chronic Kidney Disease, Periodontitis
Chronic Kidney Disease Associated Diet
The goal of this observational study is to investigate the relationship between chronic kidney disease (CKD) and periodontitis, and to evaluate the potential mediating role of dietary inflammatory potential, measured by the…
- Conditions
- Chronic Kidney Disease, Periodontitis, Diet, Food and Nutrition
- Trial name
- NCT07427069
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Periodontitis, Hemodialysis
Therapeutic Effect of Manuka Honey Oral Rinse in Periodontitis Patients Undergoing Hemodialysis
Chronic Kidney Disease (CKD) has a strong association with chronic periodontitis, an oral disease causing tooth loss linked to inflammation and malnutrition.
- Trial name
- NCT06726876
- Testing
- Manuka honey oral rinse., Normal saline rinses.
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Ain Shams University
Periodontitis (Stage 3), Periodontitis Stage IV
Application of a Fasting-mimicking Diet in Obese Patients With Periodontitis Stage III-IV
This study will evaluate whether a fasting-mimicking diet (FMD) can improve the systemic and periodontal response to non-surgical periodontal treatment in obese adults with severe periodontitis.
- Trial name
- NCT07549633
- Testing
- Fast mimicking diet group, Normal diet group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Symptomatic Apical Periodontitis
Comparison of Postoperative Pain After Double Antibiotic Paste vs Calcium Hydroxide in Teeth With Symptomatic Apical Periodontitis
This randomized controlled trial aims to compare the mean postoperative pain after using double antibiotic paste (DAP) versus calcium hydroxide (CH) as an intracanal medicament in teeth with symptomatic apical periodontitis.
- Trial name
- NCT07867951
- Testing
- Calcium Hydroxide (Ca(OH)2), Double Antibiotic Paste
- Where
- Pakistan
- Volunteers
- 662 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Periodontitis
Caffeine Intake and Periodontal Treatment Outcomes
This study will explore whether caffeine intake can affect recovery after periodontal (gum) treatment. Periodontitis is a common gum disease caused by bacteria.
- Trial name
- NCT07747545
- Testing
- No Caffeine Intake, Low Caffeine Intake, Moderate Caffeine Intake
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Haoran Feng
Periodontal Disease, Periodontitis (Stage 3)
Omega-3 Plus Low-Dose Aspirin in Smokers With Stage III Periodontitis
This randomized double-blind placebo-controlled clinical trial aims to evaluate the clinical and biochemical effects of omega-3 fatty acids combined with low-dose aspirin as an adjunct to scaling and root planing (SRP) in smoker…
- Conditions
- Periodontal Disease, Periodontitis (Stage 3), Smoking Behaviors
- Trial name
- OASP (NCT07673185)
- Testing
- Omega-3 Fatty Acids (EPA plus DHA) plus low dose aspirin
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University