Clinical trials: Perioperative
Pain, Forearm Fracture
Pain Alleviation of Forearm Fractures
fractures of upper limb induce much pain . A lot of modalities are available to alleviate pain. fracture hematoma block, and intravenous regional anesthesia seem to be cost effective and attractive options
- Trial name
- NCT03377907
- Testing
- ketamine in hematoma block, ketamine in local intravenous anesthesia, Lidocaine Hydrochloride
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Assiut University
Stomach Cancer, Gastroesophageal Junction Cancer
FLOT vs. FLOT/Ramucirumab for Perioperative Therapy of Gastric or GEJ Cancer (RAMSES)
Previous studies provide a strong theoretical rationale for the conduct of a randomized study evaluating the efficacy and safety of ramucirumab in combination with FLOT in the perioperative treatment of resectable adenocarcinoma…
- Trial name
- RAMSES/FLOT7 (NCT02661971)
- Testing
- Docetaxel, Oxaliplatin, Calciumfolinat
- Where
- 2 sites in Germany, Italy
- Volunteers
- 180 people
- Sponsor
- Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Rectal Cancer, Colon Cancer
Measurement of Perioperative Glomerular Filtration Rate
Our objective is to monitor glomerular filtration rate (GFR)during the perioperative phase of patients undergoing robotic surgery for rectum or large bowel cancers.
- Trial name
- NCT03881332
- Where
- Norway
- Volunteers
- 4 people
- Sponsor
- University Hospital of North Norway
Postoperative Pain, Postoperative Sedation
Analgesic Effect of Gabapentin in Total Knee Arthroplasty (TKA)
Pain is a major problem after TKA. Gabapentin may reduce acute postoperative pain. The investigators therefore investigate the effect of Gabapentin as a perioperative analgesic.
- Trial name
- NCT01507363
- Testing
- Gabapentin
- Where
- 3 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- Hvidovre University Hospital
Pain Management, Perioperative Analgesia
From Battlefield to Recovery: Continuous Regional Anaesthesia for War-Related Lower Limb Trauma
To compare the effectiveness of continuous regional anaesthesia with standard pain management strategies for the treatment of acute pain in patients with war-related lower limb trauma.
- Conditions
- Pain Management, Perioperative Analgesia, War-Related Injuries
- Trial name
- CRA-WAR-LIMB S (NCT07474506)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Pain
Perioperative Systemic Acetaminophen to Improve Postoperative Quality of Recovery After Ambulatory Breast Surgery
Recent evidence demonstrates that perioperative pain continues to be poorly managed among ambulatory surgical patients. More importantly, few interventions that minimize postoperative pain have also shown to improve patient…
- Trial name
- NCT01852955
- Testing
- IV acetaminophen
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Northwestern University
Femoral Neck Fractures
the Effects of Perioperative Goal Directed and Conventional Fluid Management on the IVC Collapsibility Index
The investigators aimed to compare the effects of targeted fluid management and traditional fluid management on the inferior vena cava collapsibility index in participants who will undergo proximal femoral surgery.
- Trial name
- NCT05154435
- Testing
- mostcare hemodynamic monitor
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Valve Heart Disease, Coronary Artery Disease
Construction of a Prospective Cohort Database for the Perioperative Period of Cardiac Surgery
Cardiovascular disease (CVD) is the leading cause of global morbidity and mortality, with its prevalence increasing significantly from 1990 to 2019.
- Conditions
- Valve Heart Disease, Coronary Artery Disease, Coronary Heart Disease, Aortic Diseases
- Trial name
- NCT07662317
- Testing
- Cardiac surgey
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Gastric and Gastroesophageal Junction (GEJ) Adenocarcinoma
A Phase III Clinical Study of Cadonilimab Plus SOX as Perioperative Treatment for Patients With Resectable G/GEJ Adenocarcinoma
This study investigates treatment of cadonilimab or placebo combined with SOX chemotherapy (oxaliplatin + tegafur-gimeracil-oteracil potassium) given before surgery (neoadjuvant) and cadonilimab or placebo combined with SOX…
- Trial name
- NCT07023315
- Testing
- Cadonilimab, SOX chemotherapy
- Where
- 6 sites in China
- Volunteers
- 760 people
- Sponsor
- Akeso
Perioperative Care Process Adherence
Development and Validation of the Perioperative Care Process Adherence Scale
This study aims to develop a new measurement instrument, the Perioperative Care Process Adherence Scale (PBSUO), and to evaluate its psychometric properties.
- Trial name
- PCPAS (NCT07833111)
- Where
- Turkey (Türkiye)
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Volkan Gokmen
Congenital Heart Disease
Perioperative Outcome of Congenital Heart Disease Surgery in Childhood
Congenital heart disease is the most common congenital malformation in the world with high morbidity and mortality. However, there is no data to assess the perioperative outcome of congenital heart disease surgery among Chinese…
- Trial name
- NCT04093011
- Testing
- Congenital Heart Disease Surgery
- Where
- China
- Volunteers
- 6,500 people
- Sponsor
- Nanjing Medical University
Colon Cancer
A Study of the Perioperative Use of Cetuximab in Colon Cancer Patients
There are more than 140,000 new cases of colon cancer diagnosed each year, and over 60,000 Americans die from colon cancer annually. To date, surgical resection remains the mainstay of treatment for colon cancer.
- Trial name
- NCT00494611
- Testing
- Peri operative Cetuximab.
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Hysteroscopic Myomectomy
Comparison of Perioperative Outcome Between Monopolar and Bipolar Hysteroscopic Myomectomy
Objective: To evaluate clinical outcome between monopolar and bipolar hysteroscopic myomectomy.
- Trial name
- NCT05423925
- Testing
- Bipolar hysteroscopic myomectomy, Monopolar hysteroscopic myomectomy
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- Far Eastern Memorial Hospital
Pituitary Adenoma, Pituitary Diseases
Peri-Operative Steroid Management in Patients
During transsphenoidal resection of pituitary tumors and cysts, surgery is performed by a neurosurgeon and ear nose and throat surgeon.
- Trial name
- Steroid (NCT02084134)
- Testing
- hydrocortisone, dexamethasone
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Washington University School of Medicine
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery
Opioid overuse is a widespread public health crisis in the United States with increasing rates of addiction and overdose deaths from prescription opioids.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Spondylolisthesis, Lumbar Spondylosis
- Trial name
- NCT05029726
- Testing
- Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine, normal saline
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- John O'Toole
Esmolol, Stress Reaction
Effect of Esmolol on Perioperative Stress Reaction
The goal of this clinical trial is to observe the effect of low dose continuous infusion of esmolol on perioperative stress response in patients undergoing airway intervention .
- Conditions
- Esmolol, Stress Reaction, Airway Obstruction, Catecholamine; Overproduction
- Trial name
- NCT05694585
- Testing
- Esmolol, saline
- Volunteers
- 46 people
- Sponsor
- Xiumei Song
Blood Pressure, Perioperative Hypotension
Impact of Continuous Non-invasive Blood Pressure Monitoring on Hypotension in Patients Having Non-cardiac Surgery
This is a randomized trial (1) investigating whether continuous non-invasive finger-cuff blood pressure monitoring reduces the area under a mean arterial pressure (MAP) of 65 mmHg within the first 15 minutes of anesthetic…
- Trial name
- NCT04736862
- Testing
- Continuous non-invasive blood pressure monitoring, Intermittent non-invasive blood pressure monitoring
- Where
- Germany
- Volunteers
- 242 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Bleeding
Comparison of Scoring Systems for Bleeding in Open Cardiac Surgery Patients
Seven different scoring systems used for prediction of perioperative bleeding were compared regarding patients operated for elective open cardiac surgery in the investigator's study.
- Trial name
- NCT03846622
- Testing
- Calculation of scoring systems for bleeding
- Volunteers
- 500 people
- Sponsor
- Kocaeli Derince Education and Research Hospital
Acute Ischemic Stroke
Comparison of Perioperative Conscious Sedation During Endovascular Thrombectomy in Acute Ischemic Stroke
This study aims to conduct a multicenter, prospective, randomized clinical trial to scientifically evaluate the safety and efficacy of different perioperative sedation methods during endovascular thrombectomy in acute ischemic…
- Trial name
- PEACE (NCT06139692)
- Testing
- Dexmedetomidine, Midazolam
- Where
- 4 sites in China
- Volunteers
- 810 people
- Sponsor
- Jinling Hospital, China
Colorectal Cancer, Colorecatal Cancer Surgery
Enhanced Recovery After Surgery in Patients Undergoing Colorectal Cancer Surgery
This study compared an Enhanced Recovery After Surgery (ERAS) care program with conventional perioperative care in adults undergoing surgery for colorectal cancer.
- Trial name
- NCT07889934
- Testing
- Enhanced Recovery After Surgery (ERAS) Pathway, Conventional Perioperative Care
- Where
- Greece
- Volunteers
- 91 people
- Sponsor
- University of West Attica