Clinical trials: Perioperative Anaemia
Hip Fracture, Surgical Intervention
Efficacy and Safety of Intravenous Iron Sucrose in Patients With Hip Fracture to Prevent Perioperative Anemia
The purpose of this study is to evaluate the safety and efficacy of intravenous iron sucrose in patients with hip fracture and surgical intervention to prevent perioperative anemia.
- Trial name
- NCT01084122
- Testing
- Iron sucrose
- Where
- Spain
- Volunteers
- 360 people
- Sponsor
- Hospital Clinic of Barcelona
Anemia, Coronary Disease
PBM as Strategy to CABG Anemic Patients Bypass Graft (CABG)
Anemia poses risks during coronary artery bypass grafting (CABG), increasing complications and mortality rates. Blood transfusions in cardiac surgery have negative outcomes, prompting the use of erythropoietin in Patient Blood…
- Conditions
- Anemia, Coronary Disease, Coronary Artery Disease, Coronary Stenosis
- Trial name
- NCT06542393
- Testing
- Erythropoietin, blood transfusion
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Cancer Colon
Perioperative Iron for Colorectal Cancer (PICoC Study)
The PICoC study aims to investigate whether oral ferric maltol given postoperatively offers an improvement in patient and clinician reported outcomes compared to standard care.
- Trial name
- PICoC (NCT05177484)
- Testing
- oral ferric maltol
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Hip Fracture, Anemia
The Effects of Intravenous Iron on Mobility in Elderly Patients Following Hip Fracture Surgery
The primary aim of this clinical trial is to investigate the effects of intravenous iron on recovery in mobility compared to the pre-fracture level in patients with a hip fracture The main questions it aims to answer are: It is…
- Trial name
- IronHip (NCT06898814)
- Testing
- Ferric Derisomaltose
- Where
- 3 sites in Denmark
- Volunteers
- 210 people
- Sponsor
- Soren Overgaard
Anemia, Anemia (Iron-Loading)
Evaluate the Outcomes of Ferric Carboxymaltose in Patients With Perioperative Anemia
The prevalence of preoperative anaemia in patients undergoing major surgery is approximately 30%, and is independently associated with higher mortality, a higher rate of postoperative complications, and a greater probability of…
- Conditions
- Anemia, Anemia (Iron-Loading), Perioperative Bleeding, Infection Prevention
- Trial name
- NCT06948864
- Testing
- Ferric Carboxymaltose (FCM)
- Where
- Spain
- Volunteers
- 152 people
- Sponsor
- Hospital Universitario Infanta Cristina
Iron Deficiency Anemia, Perioperative Blood Conservation
Trial Comparing the Safety of Two Different Intravenous Iron Formulations
The purpose of this trial is to compare the safety profile using equal doses of intravenous iron dextran versus iron sucrose. The researchers hypothesize that significantly more patients receiving intravenous iron dextran (using…
- Trial name
- NCT00593619
- Testing
- Iron dextran, Iron sucrose
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- London Health Sciences Centre
Anemia, Postoperative Complications
Preoperative Anaemia and Early Postoperative Complications After Major Gastrointestinal Surgery
This prospective observational cohort study evaluated the association between preoperative anaemia and early postoperative morbidity in adults undergoing major gastrointestinal surgery at the University Hospital of Ioannina…
- Trial name
- NCT07798544
- Where
- Greece
- Volunteers
- 146 people
- Sponsor
- University of Ioannina
Allogenic Transfusion, Perioperative Anaemia
Cross Iron (Comparative Randomized Oral Versus Systemic IRON)
Patients were recruited at the scheduled preoperative visit for hip or knee arthroplasty. If the haemoglobin (Hb) level was below 13 g/dl with no contraindication to iron supplementation the patients were randomized to the oral…
- Conditions
- Allogenic Transfusion, Perioperative Anaemia, Knee Arthroplasty, Hip Arthroplasty
- Trial name
- Cross Iron (NCT02496377)
- Testing
- ferrous glycine sulfate Tardyferon, Epoetin Alfa, ferric carboxymaltose Ferinject
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Anemia, Colorectal Surgery
The Change in RetHe - Levels Perioperatively in a Cohort of Colorectal Surgery Patient
During a period of a year, reticulocyte hemoglobin content (RetHe) measurements (Sysmex) are done out of blood samples taken on several occasions during normal patient care: 1.
- Conditions
- Anemia, Colorectal Surgery, Perioperative
- Trial name
- NCT03500497
- Testing
- RetHe measurement (Sysmex)
- Where
- Netherlands
- Volunteers
- 164 people
- Sponsor
- Maastricht University Medical Center
Benign Prostatic Hyperplasia, Transurethral Resection of the Prostate
Tranexamic Acid for Bleeding Reduction During TURP Surgery
Transurethral resection of the prostate (TURP) is commonly performed in elderly patients and may be associated with perioperative bleeding leading to postoperative anemia and delayed recovery.
- Conditions
- Benign Prostatic Hyperplasia, Transurethral Resection of the Prostate, Perioperative Bleeding, Anemia, Postoperative
- Trial name
- TXA-TURP (NCT07460518)
- Testing
- Tranexamic Acid
- Where
- Morocco
- Volunteers
- 80 people
- Sponsor
- Hamza Najout
Abnormal Uterine Bleeding
Role of Blood Management in Perioperative Outcomes
There is currently limited information regarding the role of blood management in the benign gynecologic population and specifically, in patients who are scheduled to undergo surgery for fibroids and/or abnormal uterine bleeding.
- Trial name
- NCT04475497
- Testing
- Blood management, Usual care
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- The Cleveland Clinic
Colorectal Neoplasm, Iron Deficiency Anemia
Iron Therapy in Colo-Rectal Neoplasm and Iron Deficiency Anemia: Intravenous Iron Sucrose Versus Oral Ferrous Sulphate.
The main objective of this study is to evaluate the efficacy of intravenous iron sucrose in increasing preoperative haemoglobin values in patients with colo-rectal neoplasm and iron deficiency anemia, compared to the standard…
- Trial name
- NCT00199277
- Testing
- i.v. iron sucrose, Oral iron
- Where
- 5 sites in Spain
- Volunteers
- 150 people
- Sponsor
- J. Uriach and Company
Transfusion-dependent Anemia
Knowledge and Attitude in Perioperative Erythrocyte Transfusion in Medical Personnel in Siriraj Hospital
This study is designed to explore the correlation between knowledge and attitude in perioperative erythrocyte transfusion in medical personnel.
- Trial name
- NCT04155021
- Where
- Thailand
- Volunteers
- 250 people
- Sponsor
- Siriraj Hospital
Heart; Dysfunction Postoperative, Cardiac Surgery, Anemia, Iron-Deficiency
Pre-operative Treatment With Erythropoietin and Iron Supplement in Cardiac Surgery
Pre-treatment of patients with erythropoietin subcutaneously and iron supplement intravenously, in order to create a clinical pathway to minimize transfusion of red blood cells in a selected group of cardiac patients with an…
- Trial name
- NCT02210949
- Testing
- Erythropoietin subcutaneously and Iron intravenously
- Where
- Netherlands
- Volunteers
- 7 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Anemia
The Effect of Preoperative Intravenous Ferric Derisomaltose and EPO and Tranexamic Acid in Patients With Preoperative Anemia or Iron Deficiency in Bone Tumor
The pelvis and spine are common sites of primary and secondary bone tumors, and most patients require surgical treatment. However, due to bleeding, high tumor burden, and other reasons, iron deficiency anemia (IDA) is common in…
- Trial name
- NCT07314424
- Testing
- isomaltose iron
- Volunteers
- 160 people
- Sponsor
- Tang Xiaodong
Anemia, Iron Deficiency, Anemia of Chronic Disease
Hemoglobin Optimization to Prevent Transfusion and Adverse Events in Perioperative Patients With Iron Restricted Anemia
The HOPE-Hb trial is a phase II study to determine the feasibility and impact of a combination treatment (intravenous iron plus erythropoietin) versus intravenous iron treatment alone on preoperative hemoglobin concentration…
- Conditions
- Anemia, Iron Deficiency, Anemia of Chronic Disease, Hip Arthropathy, Knee Arthropathy
- Trial name
- HOPE-Hb (NCT03528564)
- Testing
- Iron sucrose, Epoetin Alfa
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- Unity Health Toronto
Anemia, Delirium
Elderly With Hip Fracture and Perioperative Hemoglobin and Perfusion Index Levels
The overall aim of the study is to investigate the time difference in the diagnosing of anemia among elderly with hip fracture, between measurements with standard blood samples and non-invasive SpHb-measuring.
- Trial name
- NCT02838706
- Testing
- Surgery for hip fracture
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Hvidovre University Hospital
Anemia, Colorectal Neoplasm
IVICA: Intravenous Iron in Colorectal Cancer Associated Anaemia
116 eligible patients with confirmed non-metastatic colorectal adenocarcinoma and anemia will be randomized to receive either oral ferrous sulphate (control) or intravenous ferric carboxymaltose (intervention).
- Trial name
- IVICA (NCT01701310)
- Testing
- Ferric carboxymaltose, Ferrous Sulphate
- Where
- 8 sites in United Kingdom
- Volunteers
- 116 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Perioperative Anemia
Effect of Perioperative Roxadustat in Elective Lumbar Interbody Fusion Surgery.
The goal of this clinical trial is to assess whether Roxadustat can reduce perioperative blood transfusions in patients with anemia undergoing elective lumbar interbody fusion surgery.
- Trial name
- PRELIFS (NCT06772272)
- Testing
- Roxadustat
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Anemia, Iron Deficiency
Impact of Preoperative Treatment of Anemia and Iron Deficiency in Cardiac Surgery on Outcome.
We are performing the above prospective randomized trial in 1'000 patients undergoing cardiac surgery. The study will answer the question of whether preoperative treatment of anemia or iron deficiency indeed improves transfusion…
- Trial name
- NCT02031289
- Testing
- Erythropoietin/Ferric carboxymaltose/Vitamin B12/Folic Acid
- Where
- Switzerland
- Volunteers
- 1,003 people
- Sponsor
- University of Zurich