Clinical trials: Perioperative Management
Colorectal Disorders
Does a Central Venous Line Reduce Perioperative Fluid Administration?
'Hypothesis-generating' study to assess whether the presence of a central venous line significantly affects the volumes of fluid infused perioperatively in major elective colorectal surgery
- Trial name
- NCT03985111
- Testing
- Central Venous Catheter
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Barts & The London NHS Trust
HoLEP (Holmium Laser Enucleation of Prostate), Hyperchloremia
Metabolic and Clinical Effects of Hyperchloremia During HoLEP Surgery.
This study aims to evaluate the changes between preoperative and postoperative serum chloride levels in patients undergoing HoLEP surgery and to investigate the metabolic and clinical effects of this change.
- Conditions
- HoLEP (Holmium Laser Enucleation of Prostate), Hyperchloremia, Perioperative Management
- Trial name
- NCT07655830
- Testing
- HoLEP surgery
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Lymphedema, Perioperative/Postoperative Complications
Bioimpedance Spectroscopy in Detecting Lower-Extremity Lymphedema in Patients With Stage I, Stage II, Stage III, or Stage IV Vulvar Cancer Undergoing Surgery and Lymphadenectomy
This phase II trial studies bioimpedance spectroscopy in detecting lower-extremity lymphedema in patients with stage I, stage II, stage III, or stage IV vulvar cancer undergoing surgery and lymphadenectomy.
- Conditions
- Lymphedema, Perioperative/Postoperative Complications, Stage IA Vulvar Cancer AJCC v7, Stage IB Vulvar Cancer AJCC v7
- Trial name
- NCT01406769
- Testing
- Bioelectric Impedance Analysis, Lymphadenectomy, Therapeutic Conventional Surgery
- Where
- 11 sites in United States
- Volunteers
- 120 people
- Sponsor
- Gynecologic Oncology Group
Maxillofacial Tumors
Efficacy of Bilateral Ultrasonic Guided Sphenopalatine Ganglion Block in Maxilofacial Cancer Surgeries
Patients will be randomly allocated according to computer - generated tables to one of two groups, group (A) ultrasonic guided sphenopalatine block using local anasthetic, group (B) ultrasonic guided sphenopalatine block using…
- Trial name
- NCT03171090
- Testing
- sphenopalatine block with local anesthetic, sphenopalatine block with saline
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Assiut University
Endometriosis
Endometriosis and Pain
Endometriosis is a condition affecting about 10% of childbearing age women. It can begin a few months to a few years after puberty.
- Trial name
- EndoDOL (NCT03993197)
- Testing
- Psychological and corporal group management
- Where
- France
- Volunteers
- 91 people
- Sponsor
- Hospices Civils de Lyon
Scoliosis; Adolescence, Anesthesia Recovery Period
IV Lidocaine Analgesia in Pediatric Scoliosis Surgery
Surgical correction of scoliosis in children is a long procedure, with an equivalently long recovery time, that is commonly performed at BC Children's Hospital.
- Trial name
- P-IVLT (NCT04069169)
- Testing
- Lidocaine, Saline Solution
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of British Columbia
Perioperative Pain
Lumbar Epidural Analgesia With Bilateral Erector Spinae Block for Pain Management in Lumbar Spine Surgery
Surgical procedures on the spine and spinal cord are common and are performed for a wide variety of diseases. They range from minimally invasive, single-level decompression to highly complex, multi-stage extensive reconstruction.
- Trial name
- NCT04320212
- Testing
- lumber epidural analgesia, erector spinae analgesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Liver Disease, Pain
Comparison Between Epidural and Bilateral Paravertebral Blocks in Liver Resection
This prospective, randomized study is intended to assess the efficacy and safety of bilateral continuous paravertebral blocks compared to continuous epidural block for open liver resection.
- Trial name
- NCT01407666
- Testing
- paravertebral blocks
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pittsburgh
Airway Management, Education
The Training and Evaluate Effect on Clinical Airway Management for Novices.
In this self-control experiment, anesthesiologists without experiment of bronchoscopy working in anesthesiology department in Peking Union Medical College Hospital will receive a training and evaluation procedure in simulation…
- Conditions
- Airway Management, Education, Bronchoscopy
- Trial name
- NCT03856073
- Testing
- Novice
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Degenerative Spondylolisthesis
Multimodal Perioperative Pain Management
Convalescence after lumbar fusion is dependent on pain. In orthopaedic and abdominal surgery accelerated stay programs with optimized pain management enhance recovery.
- Trial name
- NCT01513564
- Testing
- Postoperative epidural morphine, Local anaesthesia
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Postoperative Nausea, Postoperative Vomiting
Advancing Strategies to Optimize the PerIopeRativE Management of PostOperative Nausea and Vomiting (ASPIRE-PONV) Trial
The goal of this prospective, unblinded, pragmatic and repeated crossover trial is to learn if clinical decision support alerts will impact postoperative nausea and vomiting (PONV) prophylaxis and reduce PONV rates in adult…
- Trial name
- ASPIRE-PONV (NCT07152249)
- Testing
- AW-D Clinical Decision Support Tool
- Where
- United States
- Volunteers
- 19,480 people
- Sponsor
- Vanderbilt University Medical Center
Dexamethasone, Hip Dysplasia
The Effect of Perioperative Dexamethasone Administration on Postoperative Pain in Patients Undergoing Periacetabular Osteotomy.
This is an investigator-initiated, Danish mono-center, randomized, placebo-controlled, parallel group, double-blind, superiority trial of dexamethasone on postoperative pain management on patients undergoing operation for hip…
- Conditions
- Dexamethasone, Hip Dysplasia, Postoperative Pain, Postoperative Nausea and Vomiting
- Trial name
- PAODEX (NCT03874936)
- Testing
- Dexamethasone 24mg Solution for Injection, Saline Solution for Injection
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Odense University Hospital
Complex Valvular Heart Surgery
Effect of Perioperative Iron Isomaltoside 1000 Administration on Transfusion Requirements in Patients Undergoing Complex Valvular Heart Surgery: a Randomized Clinical Trial
In complex cardiac surgery with prolonged cardiopulmonary bypass, allogeneic blood products transfusions are often necessary to control intraoperative and postoperative bleeding.
- Trial name
- NCT02862665
- Testing
- iron isomaltoside 1000 (Monofer®), normal saline 100 ml
- Where
- South Korea
- Volunteers
- 214 people
- Sponsor
- Yonsei University
Complex Obstetric Surgery, Perioperative Pain Management
COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block
To assess the effect of intraoperative transversus abdominis plane (TAP) blocks on the amount of opioid pain medications expressed as morphine milliequivalents (MME) used postoperatively in patients who have undergone cesarean…
- Conditions
- Complex Obstetric Surgery, Perioperative Pain Management, Cesarean Delivery, Postoperative Pain Control
- Trial name
- COMFORT (NCT06925152)
- Testing
- Bupivicaine intervention arm
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Tennessee
Pain Management, Perioperative Analgesia
From Battlefield to Recovery: Continuous Regional Anaesthesia for War-Related Lower Limb Trauma
To compare the effectiveness of continuous regional anaesthesia with standard pain management strategies for the treatment of acute pain in patients with war-related lower limb trauma.
- Conditions
- Pain Management, Perioperative Analgesia, War-Related Injuries
- Trial name
- CRA-WAR-LIMB S (NCT07474506)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)