Clinical trials: Perioperative Outcomes
Hypothermia, Perioperative
Prevalence Survey in France of Unintentional Perioperative Hypothermia and Its Impact on Two Outcomes
The primary objectives of the study are to perform a survey on the clinical management of unintentional hypothermia during surgery in France. to assess the impact of perioperative hypothermia on anemia and myocardial injury.
- Trial name
- HYPOTHERMIE (NCT02790086)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Société Française d'Anesthésie et de Réanimation
Laparoscopic Cholecystectomy
ERAS (Enhanced Recovery After Surgery) and Multimodal Analgesia in Laparoscopic Cholecystectomy
This clinical study aims to evaluate the effects of multimodal analgesia management administered within an ERAS (Enhanced Recovery After Surgery) protocol on postoperative pain, length of hospital stay, early complications, and…
- Trial name
- ERAS (NCT06885086)
- Testing
- Control group - 1, Observation group -2
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Perioperative Care, EEG Power Spectra
Extended Emergence Strategy on Post-Anesthesia Care Unit Events After Outpatient Orthopedic Surgery
The goal of this clinical trial is to learn if an extended emergence from anesthesia can improve recovery room (Post-Anesthesia Care Unit or PACU) outcomes in lower-leg or foot surgery with nerve blocks.
- Conditions
- Perioperative Care, EEG Power Spectra, Delirium - Postoperative
- Trial name
- PACU-EMERGE (NCT07533370)
- Testing
- Standard of Care EEG-Guided Emergence, Extended EEG Emergence Trajectory
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Harrison Shong-Wen Chow
Distal Pancreatectomy, Spleen Preservation
Comparison of Outcomes Between Warshaw and Kimura Techniques for Spleen-preserving Minimally Invasive Distal Pancreatectomy
Spleen-persevering distal pancreatectomy (SP-DP) has been widely advocated as a routine procedure for benign or low-grade malignant tumors in the pancreatic body and tail, especially with a minimally invasive approach.
- Conditions
- Distal Pancreatectomy, Spleen Preservation, Postpancreatectomy Hemorrhage
- Trial name
- NCT06084975
- Testing
- Splenic vessels preservation
- Where
- China
- Volunteers
- 314 people
- Sponsor
- Zhejiang University
Stomach Neoplasms, Metabolic Syndrome X
Effects of Prehabilitation in Gastric Cancer Patients With Metabolic Syndrome on Perioperative Outcome
A prospective randomised controlled trial to investigate the effects of a pre-operative prehabilitation protocol on clinical outcomes of gastric cancer patients with metabolic syndrome who undergo laparoscopic radical…
- Trial name
- NCT02649348
- Testing
- pre-operative prehabilitation
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Qingdao University
NSCLC
Perioperative Treatment Outcomes of Early NSCLC
This is an observational study evaluating the clinical characteristics, treatment patterns, and clinical outcomes of perioperative NSCLC patients receiving different treatment strategies.
- Trial name
- Peri-R (NCT06610240)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shanghai Chest Hospital
Smoking Cessation, Perioperative/Postoperative Complications
Perioperative Smoking Cessation Interventions
To assess impact of behavioral economic principles of precommitment, implementation intentions, and social contracting on smoking cessation for patients undergoing surgery.
- Trial name
- NCT03222908
- Testing
- Intervention1: Contract Agreement, Intervention2: Implementation Intentions
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Duke University
Pain, Postoperative
Outcomes Of Perioperative Pregabalin On Total Knee Arthroplasty
This study aims to provide high quality evidence from a double-blinded, randomized controlled trial on the efficacy of perioperative pregabalin in reducing morphine requirements, improving pain scores and reducing chronic…
- Trial name
- NCT02954484
- Testing
- pregabalin, Etoricoxib, paracetamol
- Volunteers
- 116 people
- Sponsor
- National University Hospital, Singapore
Anemia, Iron Deficiency, Hyperglycemia
Prevalence of Hyperglycemia and Anaemia in Elective Surgical Patients
The study is a prospective, observational study of adult, non-cardiac, non-obstetric, elective surgical patients conducted over a period of one week.
- Trial name
- EPIC-1 (NCT03318055)
- Where
- 6 sites in South Africa
- Volunteers
- 343 people
- Sponsor
- University of Cape Town
Atrial Fibrillation, Acute Kidney Injury
Autonomic State, Cardiovascular Control and Outcomes in Coronary Surgery
Characterization of the perioperative autonomic nervous system state, cardiovascular and cerebrovascular control and microcirculation in order to predict postoperative atrial fibrillation and acute kidney injury in patients…
- Trial name
- NCT03169608
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Policlinico S. Donato
Stent Thrombosis
PeriOperative Bridging - Perioperative Anticoagulation in the Setting of Recent Intracoronary Drug Eluting Stents
The purpose of this study is to determine if an intravenous (IV) antiplatelet medication is as safe and effective at preventing clot formation in your stented artery as compared in people who have stopped clopidogrel prior to…
- Trial name
- NCT00606151
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Cleveland Clinic
Perioperative Red Blood Cell Transfusion
Blood Transfusion Strategies During Major Surgery
The goal of this randomized clinical trial is to address the uncertainty surrounding blood transfusion strategies in the operating room for adult patients undergoing major surgery.
- Trial name
- TOPGUN (NCT07748663)
- Testing
- Restrictive Transfusion, Liberal transfusion
- Where
- 2 sites in Canada
- Volunteers
- 5,058 people
- Sponsor
- Ottawa Hospital Research Institute
Gastric Cancer, Outcomes, Pakistan, Adjuvant Chemotherapy, Perioperative Chemotherapy
COMPARATIVE EFFECTS OF PERIOPERATIVE AND ADJUVANT CHEMOTHERAPY ON OUTCOMES OF OPERABLE GASTRIC CANCER: EXPERIENCE FROM A CANCER CARE CENTER
Patients with gastric adenocarcinoma Comparison: perioperative chemotherapy vs. adjuvant therapy. Sample size differences between the two groups. Kaplan meier survival analysis, overall survival and disease free survival
- Trial name
- NCT04989764
- Volunteers
- 108 people
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Pelvic Organ Prolapse
Factors Affecting Perioperative Outcomes
The specific aim of this study is to determine if pre-existing depression and anxiety affect perioperative outcomes measures patients undergoing surgery for pelvic organ prolapse.
- Trial name
- NCT01530191
- Where
- United States
- Sponsor
- University of Oklahoma
Benign Neoplasm of Intestinal Tract, Primary Malignant Neoplasm of Intestinal Tract
Impact of Perioperative Intravenous Fluid Utilization on Postoperative Outcomes
Subjects undergoing surgery on the small or large bowel will be randomized to one of 2 groups, a normal fluid amount group and a reduced fluid amount group to evaluate the impact of this change on recovery after surgery.
- Conditions
- Benign Neoplasm of Intestinal Tract, Primary Malignant Neoplasm of Intestinal Tract, Secondary Malignant Neoplasm of Intestinal Tract
- Trial name
- NCT01563991
- Testing
- Normal fluid volume, Reduced fluid volume
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- The Cleveland Clinic
Laparoscopic Surgery
Labetalol and Esmolol: Vital Signs and Post Operative Pain Management
This study proposes to investigate the effects of labetalol or esmolol on managing the vital signs (like blood pressure and heart rate) during surgery, on pain management, and on the later recovery after surgery.
- Trial name
- NCT01114971
- Testing
- Fentanyl, Labetalol, Esmolol
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Cedars-Sinai Medical Center
Lung Cancer
The Study of High-protein Nutritional Support Impact on Postoperative Outcomes in Patients With Primary Lung Cancer
The study was aimed to evaluate the impact of perioperative nutritional support with high-protein mixtures on the risk of postoperative complications, postoperative recovery of respiratory functions in patients with lung cancer…
- Trial name
- NCT05710354
- Testing
- Nutridrink Compact Protein
- Where
- 4 sites in Russia
- Volunteers
- 114 people
- Sponsor
- Enrollme.ru, LLC
Coronary Artery Bypass Graft
Prospective Data Analysis of a Quality Improvement Initiative in High Risk Cardiac Surgery Patients
This project is designed to assess the impact of implementing a hemodynamic optimization protocol, utilizing flow guided parameters that is provided by technology from Edwards Lifesciences, for patients undergoing high risk…
- Trial name
- NCT04458701
- Testing
- Hemodynamic monitoring
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Loma Linda University
Pancreatic Adenocarcinoma, Pancreatic Cysts
Robotic Versus Open Pancreaticoduodenectomy for Pancreatic and Periampullary Tumors
This multicenter randomized trial aims to primarily assess and compare the functional recovery of patients who undergo open versus robotic pancreaticoduodenectomy for benign and malignant lesions of the head of the pancreas.
- Conditions
- Pancreatic Adenocarcinoma, Pancreatic Cysts, Pancreatic Endocrine Tumors, Chronic Pancreatitis
- Trial name
- PORTAL (NCT04400357)
- Testing
- Robotic pancreaticoduodenectomy, Open pancreaticoduodenectomy
- Where
- China
- Volunteers
- 268 people
- Sponsor
- Ruijin Hospital
Diabetes Mellitus, Postoperative Complications
Management and Outcomes of Perioperative Care Among European Diabetic Patients
The incidence of diabetes is increasing globally, including within Europe. There is an estimated 20million diabetic patients in Europe, which is likely to increase, thereby adding to societal demands on European health services.
- Trial name
- NCT04511312
- Where
- Ireland
- Volunteers
- 5,000 people
- Sponsor
- European Society of Anaesthesiology