Clinical trials: Periorbital
Facial Corrections, Facial Lines
A Study to Evaluate Satisfaction in Adult Participants With the Aesthetics of the Periorbital Area After JUVÉDERM® Fillers and BOTOX®/VISTABEL® Injections
Different studies have shown the negative effects of aging around the area of the eyes. Signs of aging may contribute to erroneously projected emotions (e.g., anger, tiredness, or sadness) that do not reflect the individual's…
- Trial name
- NCT05647551
- Testing
- BOTOX®/VISTABEL®, Juvéderm® VOLBELLA® with Lidocaine, Juvéderm® VOLIFT® with Lidocaine
- Where
- 8 sites in Australia, Belgium
- Volunteers
- 73 people
- Sponsor
- AbbVie
Facial Aging, Skin Rejuvenation
Performance and Safety of Semical Dermal Fillers in Facial Rejuvenation
The aim of the study is to verify safety and performance of Semical dermal fillers according to real-world data.
- Conditions
- Facial Aging, Skin Rejuvenation, Volume Defects in the Mid-face, Lip Augmentation and Correction of Perioral Rhytids
- Trial name
- SEMDERMA (NCT07160777)
- Testing
- cross-linked hyaluronic acid, Mesolifter
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semikal Technology
Wrinkles, Photoaging
Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines
This randomized, multi-center, double-blinded, placebo-controlled, split-face clinical trial was conducted to evaluate the procedure-pairing of OnabotulinumtoxinA with a peptide anti-aging serum to improve facial lines and…
- Conditions
- Wrinkles, Photoaging, Fine Lines
- Trial name
- NCT05089851
- Testing
- Onabotulinumtoxin A, Facial Cleanser, Facial Moisturizer
- Where
- 3 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Peri-orbital Wrinkles, Peri-oral Wrinkles
Treatment of Periorbital and Perioral Wrinkles With the Applications of the Iluminage Diode Laser
The Diode laser system is being used in this marketing study for the treatment of wrinkles around the eyes and mouth.
- Trial name
- NCT01813760
- Testing
- Illuiminage ® Diode Laser
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cynosure, Inc.
Glaucoma
Study of Application of Pulse Electrical Stimulation Around Eye in Glaucoma Patients
This study aims to evaluate the efficacy and safety of applying pulse electrical stimulation around eyes of glaucoma patients.
- Trial name
- NCT05159414
- Testing
- Pulse Electrical Stimulation
- Where
- South Korea
- Volunteers
- 18 people
- Sponsor
- Nu Eyne Co., Ltd.
Lower Eyelid Steatoblepharon (Excess Eyelid Fat)
Phase 2 Study of XAF5 (XOPH5) Ointment for Reduction of Excess Eyelid Fat (Steatoblepharon)
This study will test whether XAF5 (XOPH5) ointment, applied once daily to the lower eyelids for 10 weeks, reduces the prominence of lower eyelid fat in adults with moderate to severe steatoblepharon (excess eyelid fat).
- Trial name
- NCT02230761
- Testing
- XOPH5 Ointment
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Topokine Therapeutics, Inc.
Wrinkles
Single-Blind, Investigational Device Exemption Paired-Design, Non-Inferiority Trial With Confirmation for the Assessment of the Efficacy and Safety of a Universal Electrosurgical Device for Temporary Improvement of Mild and Moderate Wrinkles Around Both Eye Corners and Both Cheek Folds
Radiofrequency (RF) devices are commonly used for noninvasive facial rejuvenation. This study compared the efficacy and safety of 10THERMA, a newly developed monopolar RF device, with those of the Thermage FLX system.
- Trial name
- NCT07467811
- Testing
- 10THERMA, Thermage FLX
- Where
- 3 sites in South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- TENTECH INC.
Periorbital Hyperpigmentation (Dark Circles)
A Study to Determine the Safety & Efficacy of Autologous Human Platelet Lysate (HPL) in Treatment of Dark Circles
This is a multicentre, open label, randomized, pilot study to evalute safety and efficacy of Human Platelet Lysate (HPL) in subjects with Periorbital Hyperpigmentation.
- Trial name
- NCT01644448
- Testing
- Autologous Human Platelet Lysate, Standard Therapy
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Kasiak Research Pvt. Ltd.
Periorbital Wrinkles
Reducing Wrinkles Around the Eyes Using the Ulthera® System
The purpose of this prospective, multi-center, single treatment study is to evaluate the clinical outcomes associated with the non-invasive treatment to reduce wrinkles around the eyes utilizing the Ulthera® System to deliver…
- Trial name
- NCT01368900
- Testing
- Ulthera® System treatment
- Where
- 2 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Wrinkle, Periorbital
Clinical Study Evaluating the Safety and Effectiveness of The Tixel Fractional System in The Treatment of Periorbital Wrinkles
A Prospective, Multicenter, Single-Arm Clinical Study of 51 study subjects who are seeking a procedure to reduce the appearance of the peri-orbital wrinkles.
- Conditions
- Wrinkle, Periorbital, Tixel 2, Fractional
- Trial name
- NCT04639713
- Testing
- Tixel 2
- Where
- 3 sites in United States, Israel
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Novoxel Ltd.
Wrinkled Structure
A Confirmatory Study for Evaluation of the Treatment by the Celluma3 of Periorbital Wrinkles
The primary objective of this study is to confirm the safe and effective use of the Celluma3 for the reduction in the appearance of periorbital wrinkles.
- Trial name
- NCT02543970
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- BioPhotas
Ecchymosis After Periorbital Rejuvenation With Botulinum Toxin Type A, Crow's Feet Lines
A Real-World Study on Effect of Hirudoid on Ecchymosis After Treatment of Crow's Feet With Botulinum Toxin Type A
Botulinum toxin type A (commonly referred to as 'Botox') injections are a treatment that dermatologists regularly use to smoothen wrinkles such as 'Crow's feet', to rejuvenate the skin surrounding the eye (the 'periorbital…
- Conditions
- Ecchymosis After Periorbital Rejuvenation With Botulinum Toxin Type A, Crow's Feet Lines, Lateral Canthal Lines, LCL
- Trial name
- NCT07388927
- Testing
- Hirudoid (heparinoids) ointment, 3mg/g
- Volunteers
- 48 people
- Sponsor
- DKSH Management (Thailand) Limited
Periorbital Hyperpigmentation, Periorbital Edema
A 12 Week Study to Evaluate the Efficacy of an Eye Cream
This single center, open-label clinical study was conducted to assess the efficacy and tolerance of a topical eye cream when used over the course of 12 weeks by healthy women with moderate to severe under-eye dark circles…
- Conditions
- Periorbital Hyperpigmentation, Periorbital Edema, Fine Lines, Wrinkle
- Trial name
- NCT05807620
- Testing
- Gentle Cleansing Lotion, Facial Moisturizer, Sunscreen SPF 30
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Wrinkle
Confirmatory Study: Assessing the Efficacy and Safety of the AcusMu Microneedle Patch in Treating Periorbital Wrinkles
The core objective of this study is to validate the safe and efficacious application of the AcusMu microneedle patch (FMD WK) to enhance the appearance of periorbital wrinkle
- Trial name
- NCT06158867
- Testing
- FMD WK
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AcusMu Medtech Co., Ltd.
Periorbital Edema
Energy-Based Lower Eyelid Rejuvenation - Proof of Concept for InMode AccuTite With or Without Morpheus8
1. To establish clinical efficacy, safety and patient satisfaction of reducing lower eyelid convexities or "bags" and/or malar crescents (festoons) with catheter-based injectable RF (InMode AccuTite) and variable depth Fractional…
- Trial name
- NCT04103619
- Testing
- AccuTite, AccuTite + Morpheus 8
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- InMode MD Ltd.
Periorbital Wrinkles
Evaluation of the Safety and Performance of Epicare for the Treatment of Periorbital Wrinkles
This is a prospective, interventional, evaluator-blinded, multi-center clinical study designed to assess the safety and performance of the Epicare fractional nano-thulium (Tm:YAP 1938 nm) laser system for the treatment of…
- Trial name
- NCT07114562
- Testing
- Epicare
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laser team Ltd
Periorbital Wrinkles
Safety and Efficacy of XP200 Radiofrequency Treatment of Wrinkles
To evaluate the wrinkle-reducing effects of 3.25-MHz radiofrequency (RF) energy delivered in 4 weekly applications to human periorbital skin area by grating pre- and 90-days post treatment photographs on the Fitzpatrick Wrinkle…
- Trial name
- NCT01795417
- Testing
- RF XP200, XP200 RF device
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Intracranial Pressure
Validation of Non-Invasive Intracranial Pressure Estimation Using CPMX3 in the Periorbital Vein: A Feasibility Study in Pediatric Patients
Intracranial pressure (ICP) monitoring is indicated in a wide range of neurological diseases. The combination of a linear ultrasound array with an integrated pressure sensor into a single handheld probe (ICP Probe) enables the…
- Trial name
- VENUS-ICPxP (NCT07550361)
- Testing
- CPMX3 measurement
- Where
- United States
- Sponsor
- Compremium AG