Clinical trials: Peripheral Arterial Obstructive Disease
Intermittent Claudication, Critical Limb Ischemia
Choice of Material for Above-Knee Femoro-Popliteal Bypass Prosthetic Graft (PopUp)
This trial was designed to challenge the wide held view that polytetrafluoroethylene (PTFE) performs better than Dacron for above knee femoropopliteal bypass.
- Trial name
- NCT00300690
- Testing
- 6 mm Uni-graft® (B-Braun), 6 mm Gore-Tex® (WL Gore)
- Volunteers
- 400 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Intermittent Claudication
An E-health Intervention for Patients With Peripheral Artery Disease
The specific study aim is to determine whether a 12-week digitally delivered behavior change intervention for patients with peripheral artery disease increases walking ability, reduces smoking, improves quality of life and…
- Trial name
- I-PAD (NCT05029739)
- Testing
- A PAD-specific smartphone application (e-intervention) developed for patients with Peripheral Artery Disease
- Where
- 5 sites in Sweden
- Volunteers
- 155 people
- Sponsor
- Sahlgrenska University Hospital
Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia
The ROAMM-EHR Study
In recent years, mobile health (mHealth) apps have promised improved monitoring of health conditions to improve clinical outcomes.
- Trial name
- ROAMM-EHR (NCT06263322)
- Testing
- Actionable remotely generated health data, Non-Actionable remotely generated health data
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Florida
Atrial Fibrillation, Valvular Heart Disease
Prolongation of the Interval Between Prothrombin Time Tests in Stable Patients II
More than 2 million patients in North America are treated with warfarin - a "blood thinner" - to prevent blood clots in arteries or veins.
- Conditions
- Atrial Fibrillation, Valvular Heart Disease, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- PRINT-II (NCT01654042)
- Testing
- Prolonged interval between PT testing
- Where
- Canada
- Sponsor
- McMaster University
Aneurysm Abdominal, Peripheral Arterial Disease
Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression
The VASCULAID-RETRO study, within the broader VASCULAID project, aims to create artificial intelligence (AI) algorithms that can predict cardiovascular events and the progression of abdominal aortic aneurysm (AAA) and peripheral…
- Trial name
- VASCULAIDRETRO (NCT06206369)
- Testing
- No intervention, retrospective study
- Where
- 6 sites in Finland, Germany and 4 more
- Volunteers
- 11,000 people
- Sponsor
- Amsterdam UMC, location VUmc
Ischemia, Peripheral Arterial Disease
Cook Micronized Small Intestinal Submucosa (SIS) for Critical Limb Ischemia
This study is intended to collect safety and effectiveness data on the Cook Micronized Small Intestinal Submucosa (SIS)
- Conditions
- Ischemia, Peripheral Arterial Disease, Peripheral Vascular Diseases
- Trial name
- NCT02044666
- Testing
- Micronized Small Intestinal Submucosa (SIS)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Cook Group Incorporated
Symptomatic Vascular Disease of the Iliac Arteries
FORMAT Clinical Study
The FORMAT Clinical Study is a clinical trial to evaluate the safety and effectiveness of the Formula™ 535 Iliac Balloon-Expandable Stent in treatment of symptomatic vascular disease of the iliac arteries.
- Trial name
- NCT01804088
- Testing
- Formula™ 535 Iliac Balloon-Expandable Stent
- Where
- 12 sites in United States
- Volunteers
- 80 people
- Sponsor
- Cook Group Incorporated
Popliteal Entrapment Syndrome
Popliteal Artery Entrapment Syndrome & TRanscutaneoUS Oxymetry
Aim of the study is to test the feasibility of transcutaneous oxygen pressure (TcPO2) recording in the diagnosis of popliteal entrapment syndrome (PES) in 30 patients with suspected PES and 30 asymptomatic control heathy subjects
- Trial name
- PETRUS (NCT03356379)
- Testing
- Transcutaneous oximetry
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Peripheral Arterial Disease
Athrectomy and Drug Eluting Balloon Therapy (ADEBT) on the Femoral Popliteal Arteries
The aim of this study is to study the effects of athrectomy followed by percutaneous transluminal angioplasty using Paclitaxel coated Drug Eluting Balloon (DEB) in treating de novo or re-stenotic lesions in the femoral-popliteal…
- Trial name
- ADEBT (NCT02686541)
- Testing
- Atherectomy followed by Drug Eluting Balloon (DEB)
- Where
- Singapore
- Sponsor
- Changi General Hospital
Diabetes, Critical Limb Ischemia
Diabetic Foot and Vascular Progenitor Cells
Type of Study: Pilot Study monocenter Study Duration: 18 months Subject Participation Duration: The patients are enrolled for the time of the blood withdrawl. Follow up visit will be after 12 months from the enrollement.
- Trial name
- NCT01269580
- Where
- Italy
- Volunteers
- 122 people
- Sponsor
- IRCCS Multimedica
Peripheral Arterial Disease
The Effects of Omega-3 Fatty Acids Supplementation on Endothelial Function and Inflammation
The hypothesis being tested is that in patients with stable claudication and documented PAD, omega-3 supplementation for 1 month will lead to improvement in endothelial function as measured by flow-mediated, brachial artery…
- Trial name
- OMEGA-PAD (NCT01310270)
- Testing
- Pro-Omega, Omega 3 Fatty Acid
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of California, San Francisco
Atherosclerosis, Peripheral Vascular Disease
ESPRIT I: A Clinical Evaluation of the Abbott Vascular ESPRIT BVS (Bioresorbable Vascular Scaffold) System
The purpose of the ESPRIT I Clinical Investigation is to evaluate the safety and performance of the ESPRIT BVS in subjects with symptomatic claudication from occlusive vascular disease of the superficial femoral (SFA) or common…
- Conditions
- Atherosclerosis, Peripheral Vascular Disease, Claudication
- Trial name
- NCT01468974
- Testing
- ESPRIT BVS
- Where
- 8 sites in Austria, Belgium and 2 more
- Volunteers
- 35 people
- Sponsor
- Abbott Medical Devices
Peripheral Vascular Disease (PVD), Peripheral Arterial Disease (PAD)
A Clinical Trial to Evaluate the Efficacy and Safety of a Spot Stent System Used in Femoropopliteal Arteries.
A prospective randomized trial designed to compare the efficacy and safety of spot stent system versus self-expanding peripheral stent system in the endovascular treatment of femoropopliteal arterial stenotic disease.
- Trial name
- NCT05246410
- Testing
- Spot stent system, Self-expanding peripheral stent system
- Where
- 2 sites in China
- Volunteers
- 196 people
- Sponsor
- Acotec Scientific Co., Ltd
Peripheral Arterial Disease, Claudication
Intensive Rehabilitation in Peripheral Arterial Disease With Claudication: Effects of a Treadmill Training With Active Recovery
Rehabilitation is the first intention treatment of peripheral arterial disease (PAD) with claudication. Initially proposed in the sixty's, rehabilitation programs dedicated to patients with PAD have recently been proved effective…
- Trial name
- ARTEX (NCT01734603)
- Testing
- experimental rehabilitation program, conventional rehabilitation program
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Diabetes Mellitus, Type 2, Diabetic Foot
Non-invasive Imaging for In-vivo Quantification of Skin Composition and Structure
The goal of this clinical investigation is to explore a non-invasive technology for measuring the microcirculatory structure, composition and function in patients from a primary care population. The main aims are: 1.
- Conditions
- Diabetes Mellitus, Type 2, Diabetic Foot, Peripheral Arterial Disease, Skin Cancer
- Trial name
- Spectrum1 (NCT06976073)
- Where
- 3 sites in Sweden
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- HJN Sverige AB/Neko Health
Peripheral Arterial Disease
Effectiveness of Paclitaxel-coated Luminor® Balloon Catheter Versus Uncoated Balloon Catheter in the Arteria Femoralis Superficialis
The aim of this clinical trial is to evaluate the safety and efficacy of the novel Luminor® paclitaxel drug-eluting balloon (iVascular, S.L.U., Barcelona, Spain) in inhibiting restenosis and in ensuring long-term patency.
- Trial name
- EffPac (NCT02540018)
- Testing
- Transluminal Angioplasty with Paclitaxel-coated Luminor® Balloon Catheter in the Superficial Femoral and Popliteal Arteries, Transluminal Angioplasty with and non-coated (CE-marked) plain old angioplasty balloon (POBA) catheter
- Where
- 11 sites in Germany
- Volunteers
- 172 people
- Sponsor
- Jena University Hospital
Peripheral Artery Disease, Atherectomy in Diseased Lower Extremity Arteries
Rotational Atherectomy and Drug-Coated Balloon Angioplasty With Embolic Protection for Superficial Femoral Artery Occlusions
Peripheral artery disease can reduce blood flow to the legs. In some patients, the superficial femoral artery, a major artery in the thigh, is completely blocked over a long segment.
- Trial name
- NCT07803718
- Testing
- Rotational Atherectomy With Distal Embolic Protection and Drug-Coated Balloon Angioplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Peripheral Arterial Disease, Cardiovascular Diseases
Assessing the Feasibility of Including Patients With Peripheral Artery Disease in to an Established Cardiac Rehabilitation Service.
This study will investigate if patients with peripheral artery disease (PAD) can be successfully incorporated into an already existing Cardiac Rehabilitation programme.
- Conditions
- Peripheral Arterial Disease, Cardiovascular Diseases, Intermittent Claudication, Coronary Artery Disease
- Trial name
- NCT03564080
- Testing
- Combined - PAD and CAD
- Where
- United Kingdom
- Volunteers
- 57 people
- Sponsor
- University of Salford
Peripheral Arterial Disease, Peripheral Vascular Diseases
Real-World Registry Assessing the Clinical Use of the Lutonix 035 Drug Coated Balloon Catheter
The objective of this patient registry is to assess the clinical use of the Lutonix 035 DCB PTA Catheter in a heterogeneous patient population in a real world and on-label clinical application.
- Conditions
- Peripheral Arterial Disease, Peripheral Vascular Diseases, Arterial Occlusive Diseases
- Trial name
- SAFE-DCB (NCT02424383)
- Testing
- PTA (Lutonix® 035 DCB Catheter)
- Where
- 73 sites in United States
- Volunteers
- 1,005 people
- Sponsor
- C. R. Bard
Peripheral Artery Disease
Peripheral Artery Disease in Patients With Stable Coronary Artery Disease in General Practice: Prevalence, Management and Clinical Outcomes.
Patients with lower extremity peripheral artery disease (PAD) are at risk of developing major adverse limb events and have a similar cardiovascular (CV) morbidity and mortality to those with coronary artery disease (CAD) with…
- Trial name
- PAD&CAD (NCT03921905)
- Testing
- ABI measurement
- Where
- 4 sites in Italy
- Volunteers
- 713 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
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