Clinical trials: Peripheral Arterial Obstructive Disease
Influence of PRU Values on Primary Outcome
High on Treatment Platelet Reactivity Following Peripheral Endovascular Procedures
Antiplatelet therapy with clopidogrel is recommended following peripheral endovascular procedures. The clinical significance of an inadequate response to clopidogrel following percutaneous coronary interventions has been recently…
- Trial name
- PRECLOP (NCT01744613)
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Patras
Peripheral Arterial Disease
L-Citrulline in Peripheral Artery Disease
Some studies have reported improved vascular function with the supplementation of L-arginine in participants with cardiovascular disease (CVD).
- Trial name
- CIPER (NCT02521220)
- Testing
- L-citrulline
- Where
- 3 sites in Germany, Netherlands
- Volunteers
- 49 people
- Sponsor
- Maastricht University
Intermittent Claudication, Peripheral Vascular Disease
Efficacy and Safety of NM-702 Tablets for the Treatment of Intermittent Claudication
NM-702 oral tablets are being developed for the treatment of Intermittent Claudication, a primary early stage indication of peripheral arterial disease (PAD).
- Trial name
- NCT00102050
- Testing
- NM-702 (phosphodiesterase inhibitor)
- Where
- 17 sites in United States
- Volunteers
- 390 people
- Sponsor
- Nissan Chemical Industries
Peripheral Artery Disease
Bard LifeStent and Lutonix DCB for Treatment of Long Lesions in Femoropopliteal Arteries
Objective of this study is to evaluate the safety and efficacy of Lutonix 035 Drug Coated Dilatation PTA Catheter with Bard LifeStent Vascular Stent (hereinafter referred to as LifeStent) for treatment of long (10-24 cm) lesions…
- Trial name
- NCT02278991
- Testing
- Lutonix Drug Coated Balloon
- Where
- 12 sites in Germany, Greece and 1 more
- Volunteers
- 149 people
- Sponsor
- C. R. Bard
Peripheral Artery Disease, Claudication, Intermittent
Passive Calf Stretching Therapy in Peripheral Artery Disease
The goal of this clinical trial is to assess the effects of passive calf muscle stretching in patients diagnosed with peripheral artery disease (PAD). The main question it aims to answer are: 1.
- Trial name
- NCT06041880
- Testing
- Passive calf muscle stretching device
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Penn State University
Peripheral Arterial Disease
Stellarex Vascular E-Registry
Prospective, international, multi-center, single arm, observational study to continue to assess the treatment by the Stellarex™ OTW Drug-coated Angioplasty Balloon in superficial femoral and/or popliteal arteries according to the…
- Trial name
- SAVER (NCT02769273)
- Testing
- Percutaneous Transluminal Angioplasty
- Where
- 46 sites in Austria, Belgium and 4 more
- Volunteers
- 1,900 people
- Sponsor
- Spectranetics Corporation
Peripheral Arterial Disease
The Efficacy of Heparin-boned Viabahn Endoprosthesis and Paclitaxel-coated Balloons for Complex Femoropopliteal Lesions
The purpose of this study is to evaluate the effectiveness of the Viabahn endoprosthesis for treating long femoropopliteal lesions (stenosis ≥ 25cm, occlusion ≥ 15cm) or recurrent in-stent restenosis compared to drug-coated…
- Trial name
- NCT06124755
- Testing
- Viabahn endoprosthesis group, Drug-coated balloon group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- RenJi Hospital
Critical Limb Ischemia, Buerger Disease
Study to Assess the Efficacy and Safety of CLBS12 in Patients with Critical Limb Ischemia (CLI)
A prospective, open label, controlled, randomized, double arm, multi-center study to assess the efficacy and safety of CLBS12 in patients with critical limb ischemia (CLI) due to arteriosclerosis obliterans (ASO) with a single…
- Conditions
- Critical Limb Ischemia, Buerger Disease, Thromboangiitis Obliterans, Atherosclerosis Obliterans
- Trial name
- NCT02501018
- Testing
- CLBS12, SOC
- Where
- 12 sites in Japan
- Volunteers
- 33 people
- Sponsor
- Lisata Therapeutics, Inc.
Magnetic Resonance Angiography, Peripheral Vascular Diseases
Magnevist (SH L 451A) Intra-individual Dose Comparison Study in Magnetic Resonance Angiography
The objective of the study was to compare the efficacy of Magnevist (SH L 451 A) at doses of 0.1 mmol/kg and 0.2 mmol/kg in contrast-enhanced 3D-Magnetic Resonance Angiography in three regions (abdominal, femoral, and leg…
- Conditions
- Magnetic Resonance Angiography, Peripheral Vascular Diseases, Peripheral Arterial Diseases
- Trial name
- NCT00652418
- Testing
- Gadopentetate dimeglumine (Magnevist, BAY86-4882, SH L 451A)
- Where
- 3 sites in Japan
- Volunteers
- 12 people
- Sponsor
- Bayer
Atherosclerosis, Arteriosclerosis
BIOLUX P-I First in Man Study
A prospective, multi-centre, randomized controlled, First in Man study to assess the safety and performance of the coated Passeo-18 Lux Paclitaxel releasing PTA Balloon Catheter vs.
- Conditions
- Atherosclerosis, Arteriosclerosis, Vascular Disease, Peripheral Artery Disease
- Trial name
- NCT01221610
- Testing
- Passeo-18 Lux DRB, Standard PTA (POBA)
- Where
- 5 sites in Austria, Germany
- Volunteers
- 60 people
- Sponsor
- Biotronik AG
Myocardial Ischemia, Coronary Artery Disease
Peripheral Endothelial Function Assessment of Patients on Ticagrelor vs. Clopidogrel Who Have Undergone PCI
Usage of antiplatelet agents and cardiac procedures such as coronary angioplasty has dramatically improved the morbidity and mortality associated with coronary artery disease.
- Conditions
- Myocardial Ischemia, Coronary Artery Disease, Endothelial Dysfunction
- Trial name
- NCT02469740
- Testing
- Ticagrelor, Clopidogrel
- Where
- Ireland
- Volunteers
- 61 people
- Sponsor
- University Hospital of Limerick
Peripheral Artery Disease
Exercise Testing in Peripheral Artery Disease Patients
The aim of this study was to evaluate exercise testing in case of patients suspected of Peripheral Artery Disease (PAD).
- Trial name
- ExercisePAD (NCT03186391)
- Testing
- Data collected
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Rennes University Hospital
Femoral Artery Stenosis, Angioplasty
an Observational Study Evaluting the Effectiveness and Safety of DKutting LL Noval Scoring Balloon Angioplasty for Vessel Preparation Facilitated by IVUS on the Lower Limb Ischemia Patients With Calcified Lesions
This is a prospective, single-center, single-arm, observational study. It plans to enroll 58 patients with moderate to severely calcified lesions in the femoropopliteal or infrapopliteal arteries.
- Conditions
- Femoral Artery Stenosis, Angioplasty, Cutting Balloon Angioplasty, Calcifications, Vascular
- Trial name
- DkuLL CALVEP (NCT07397390)
- Testing
- DKutting LL scoring balloon angioplasty
- Where
- China
- Volunteers
- 58 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Peripheral Arterial Occlusive Disease
CO2-Angiography-Study to Evaluate Diagnostic and Safety to Patients With Peripher Arterial Stenotic or Occlusive Disease.
This randomized study focuses on the diagnostic quality and safety of CO2 application as contrast medium through an innovative injector of AngioDroid in angiography interventions in patients with peripheral arterial occlusive…
- Trial name
- ACDA-RCT (NCT05590182)
- Testing
- Angiography
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Jena University Hospital
Peripheral Arterial Disease
The Jetstream G3™ Calcium Study
To investigate the treatment effects with the Jetstream G3 System in moderate to severely calcified peripheral artery disease in the common femoral, superficial femoral or popliteal arteries using intravascular ultrasound (IVUS).
- Trial name
- NCT01273623
- Testing
- Jetstream Atherectomy System
- Where
- 5 sites in United States
- Volunteers
- 55 people
- Sponsor
- Boston Scientific Corporation
Anticoagulant Drugs, Antiplatelet Drug
Effect of Anticoagulant Drug Intervention on Postoperative MALE and MACE in Patients With PAD
Patients with PAD were grouped according to the combination of different anticoagulant and antiplate drugs. The type, dosage and duration of anticoagulant and antiplatelet drugs were recorded after operation.
- Conditions
- Anticoagulant Drugs, Antiplatelet Drug, Peripheral Arterial Disease
- Trial name
- NCT05852197
- Testing
- anticoagulant or antiplatelet drugs
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Diabetes Complications, Peripheral Arterial Disease
Collaborative-care Rehabilitation After Dysvascular Amputation
The objective of this study is to examine the feasibility of using a collaborative-care, home-based rehabilitation program to improve functional outcomes for people recovering from lower limb amputation caused by vascular…
- Trial name
- NCT01929018
- Testing
- Exercise, Walking Program, Health Self-Management Support
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Colorado, Denver
Dyslipidemias, Peripheral Artery Disease
Cilostazol-Simvastatin Drug Interaction Study
This is a randomized, open-label, single \& multiple-dose, parallel study to investigate the effect of cilostazol on the disposition of simvastatin \& pravastatin in healthy male volunteers
- Trial name
- NCT02431013
- Testing
- Simvastatin, Pravastatin, Cilostazol
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ajou University School of Medicine
Peripheral Arterial Disease
Gut Microbiota in Patients With Peripheral Arterial Disease and Chronic Limb-threatening Ischemia
Microbiota has been associated with risk factors for cardiovascular diseases (hypertension, obesity, dyslipidemia, diabetes mellitus, heart failure).
- Trial name
- NCT05757297
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Peripheral Arterial Disease (PAD)
Amplitude Vascular Systems (AVS) Lithotripsy POWER PAD 2 Trial
POWER PAD 2 is a prospective, single-arm, multicenter, non-randomized clinical study designed to demonstrate the safety and effectiveness of the Amplitude Vascular Systems (AVS) Pulse Intravascular Lithotripsy™ (Pulse IVL™)…
- Trial name
- POWER PAD 2 (NCT06457685)
- Testing
- Pulse Intravascular Lithotripsy (Pulse IVL)
- Where
- 19 sites in United States
- Volunteers
- 115 people
- Sponsor
- Amplitude Vascular Systems, Inc.
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