Clinical trials: Peripheral Arterial Vascular Occlusion
Peripheral Arterial Disease
Motivational Interviewing (MI) for African Americans With Peripheral Arterial Disease (PAD) Pilot
The investigators are conducting a pilot study for a clinical research trial to establish the feasibility and acceptability of the intervention and the most effective recruitment strategies prior to the full study.
- Trial name
- NCT01332058
- Testing
- Motivational Interviewing
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Tracie Collins, MD, MPH
Lymphoma
Revlimid® Capsules Drug Use-results Surveillance (Relapsed or Refractory ATLL)
To understand the safety and efficacy of Revlimid® Capsules 2.5 mg and 5 mg (hereinafter referred to as Revlimid) under actual conditions of use in patients with relapsed or refractory adult T-cell leukemia lymphoma (hereinafter…
- Trial name
- NCT03098589
- Testing
- Revlimid
- Where
- Japan
- Volunteers
- 1,149 people
- Sponsor
- Celgene
Critical Limb Ischemia
A Safety and Efficacy Study of Autologous Bone Marrow Derived Mesenchymal Stem Cells in Critical Limb Ischemia
This clinical trial to study the Safety and Efficacy of Autologous Mesenchymal stem cells in critical limb ischemia.
- Trial name
- NCT02477540
- Testing
- Cellgram-CLI
- Sponsor
- Pharmicell Co., Ltd.
Critical Limb Ischemia
Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia
The purpose of this study is to evaluate whether intramuscular injections of VM202 into the calf is safe and effective in the treatment of critical limb ischemia.
- Trial name
- NCT01064440
- Testing
- Low Dose VM202, High Dose VM202
- Where
- 16 sites in United States, South Korea
- Volunteers
- 52 people
- Sponsor
- Helixmith Co., Ltd.
Peripheral Artery Disease, Exercise
Response to Exercise and Nitric Oxide in PAD
RESIST PAD is a randomized trial of 200 PAD patients to establish: 1) whether a 12-week exercise intervention significantly increases Δ nitrite at 12-week follow-up, compared to control; 2) whether exercise "responders" have…
- Conditions
- Peripheral Artery Disease, Exercise, Intermittent Claudication, Nitric Oxide
- Trial name
- RESIST (NCT06657976)
- Testing
- Supervised Treadmill Exercise, Attention Control, Nitrate-Rich Beetroot Juice + supervised exercise therapy
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
Critical Limb Ischemia
Study to Assess Efficacy and Safety of Bone Marrow Derived Stem Cells in Patients With Critical Limb Ischemia
This study will assess the safety and efficacy of intra-arterial infusion and intramuscular injection of an autologous, bone marrow-derived stem cell preparation (ASCT01) in patients with critical limb ischemia who have exhausted…
- Trial name
- CLI (NCT01867190)
- Testing
- ASCT01 (Autologous Stem Cell Transplantation)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Lifecells, LLC.
Chronic Limb Threatening Ischemia, Infrapopliteal Arterial Occlusive Disease
Revascularization of Single Vesrus Multiple Infrapopliteal Vessels in Chronic Limb Threatening Ischemia
This interventional prospective study aims to assess the effectiveness of single vessel versus multiple vessel infrapopliteal angioplasty in patients with chronic threatening limb ischemia .
- Trial name
- NCT07068789
- Testing
- balloon angioplasty
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Chronic Limb-Threatening Ischemia
Woundsome Revascularization in Chronic Limb-Threatening Ischemia
Chronic limb-threatening ischemia (CLTI) is the most severe form of peripheral artery disease and remains a major health problem.
- Trial name
- NCT07488637
- Testing
- Revascularization by Percutaneous Transluminal Angioplasty
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Critical Limb Ischemia, Chronic Limb-Threatening Ischemia
PROMISE I Early Feasibility Trial of the LimFlow Stent Graft System
This pilot study will investigate the safety, effectiveness and feasibility of the LimFlow Stent Graft System for creating an AV fistula in the Below The Knee (BTK) vascular system using an endovascular, minimally invasive…
- Trial name
- NCT03124875
- Testing
- LimFlow System
- Where
- 7 sites in United States
- Volunteers
- 32 people
- Sponsor
- LimFlow, Inc.
Peripheral Artery Disease (PAD)
Prestige Pilot - Phoenix Atherectomy and Stellarex DCB Clinical Investigation in Infrapopliteal Interventions
This pilot study is to investigate if a lesion preparation strategy with Phoenix atherectomy before DCB (drug coated balloon) usage in patients with PAD (peripheral artery disease) Rutherford Stage 4-5 and mild/moderate/severe…
- Trial name
- NCT03744572
- Where
- 5 sites in Germany
- Volunteers
- 56 people
- Sponsor
- Michael Lichtenberg, MD
Popliteal Artery Disease, Superficial Femoral Artery Disease
A Study Comparing the MAGICTouch™ Sirolimus-coated Balloon With a Paclitaxel-coated Balloon for Treating Severe Narrowing or Blockage in the Femoropopliteal Arteries.
Percutaneous Transluminal Angioplasty (PTA), in which a balloon is advanced and inflated in the obstructed artery for several seconds to minutes, has become the standard endovascular treatment for peripheral arteries.
- Trial name
- MAGICAL SFA (NCT07359807)
- Testing
- Sirolimus (RAPAMUNE) drug-coated balloon angioplasty catheter, Paclitaxel drug-coated balloon angioplasty
- Volunteers
- 478 people
- Sponsor
- Concept Medical Inc.
Peripheral Arterial Occlusive Disease, Atherosclerosis
Remote Endarterectomy Versus Suprageniculate Femoropopliteal Bypass
The objective of this study is to compare remote superficial femoral artery endarterectomy with suprageniculate bypass surgery in the treatment of long occlusions of the superficial femoral artery.
- Trial name
- REVAS (NCT00566436)
- Testing
- Remote endarterectomy of the superficial femoral artery, Suprageniculate femoropopliteal bypass
- Where
- 4 sites in Netherlands
- Volunteers
- 126 people
- Sponsor
- St. Antonius Hospital
Peripheral Arterial Disease, Endovascular Procedures
Short vs Long Duration Dual Antiplatelet Therapy in Patients Undergoing Lower Extremity Endovascular Revascularization
The primary objective of the trial is to evaluate short versus long duration dual antiplatelet therapy in patients undergoing lower extremity endovascular revascularization.
- Trial name
- NCT02433587
- Testing
- Aspirin, Clopidogrel
- Where
- United States
- Sponsor
- University Hospitals Cleveland Medical Center
Femoropopliteal Artery Disease
Korean Multicenter Registry of INNOVA Stent for Femoropopliteal Artery Disease: (K-INNOVA Registry)
Prospective, single-arm, multi-center registry study A total of 150 subjects with femoropopliteal artery disease who meet all inclusion and exclusion criteria will be included.
- Trial name
- NCT02701816
- Testing
- innova stent (Boston scientific)
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Yonsei University
Peripheral Arterial Disease
DURABILITY+ : a Prospective, Multi-center, Controlled Study With the Everflex+ Stent in SFA Lesions
The objective of this study is to evaluate the immediate and long-term (up to 12 months) safety and effectiveness of primary stenting with the Protégé Everflex+ stent system for the treatment of superficial femoral artery (SFA)…
- Trial name
- DURABILITY+ (NCT01412463)
- Testing
- stent placement
- Where
- 3 sites in Belgium
- Volunteers
- 60 people
- Sponsor
- Flanders Medical Research Program
Foot Ulcers, Diabetic, Plantar Foot Pressure
Plantar Load Analysis of Neuropathic and Neuroischaemic Diabetes-Related Foot Ulceration
This single-centre observational case-control study investigates how peripheral arterial disease influences plantar load in people with diabetes who have recently healed a plantar foot ulcer.
- Conditions
- Foot Ulcers, Diabetic, Plantar Foot Pressure, Fat Pad Atrophy, Peripheral Arterial Disease
- Trial name
- PLANE-DFU (NCT07901478)
- Testing
- Pedar™ In-Shoe Plantar Pressure Measurement System, STAMPS 3D Digital Image Correlation System, Weight-Bearing Ultrasound of the Plantar Fat Pad
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Peripheral Arterial Disease (PAD), Ankle Brachial Index
Automated ABPI in Peripheral Arterial Disease a Pilot Study
The aim of this pilot study is to investigate the diagnostic accuracy of two automated ABPI devices across the spectrum of PAD (asymptomatic PAD, suspected symptomatic PAD [IC; including mild moderate and severe IC based on the…
- Conditions
- Peripheral Arterial Disease (PAD), Ankle Brachial Index, Diagnostic Accuracy, Feasibility Studies
- Trial name
- AUTO-PAD (NCT07850349)
- Testing
- MESI mTablet, BlueDop vascular Expert (BlueDopVE)
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Sarpogrelate, Blood Viscosity
A Study to Compare the Effects of Sarpogrelate Sustained Release /Aspirin Combination Therapy Versus Aspirin on Blood Viscosity in the Patients With Peripheral Arterial Disease and Coronary Artery Disease
This study is to compare the effects of sarpogrelate sustained release /aspirin combination therapy versus aspirin on blood viscosity in the patients with peripheral arterial disease and coronary artery disease
- Conditions
- Sarpogrelate, Blood Viscosity, Peripheral Arterial Disease, Coronary Artery Disease
- Trial name
- NCT05730621
- Testing
- Sarpogrelate Sustained Release/Aspirin, Aspirin
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Yuhan Corporation
Peripheral Arterial Disease
Effect of a Hybrid Rehabilitation Program on Walking, Quality of Life & Cardiovascular Risk in People With PAD
Peripheral arterial disease (PAD), a disabling condition, affects 800,000 Canadians. People with PAD suffer from poor quality of life due to leg pain, which makes walking difficult. They also have a high risk of heart disease.
- Trial name
- HY-PAD (NCT03649204)
- Testing
- HY-PAD
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Critical Limb Ischemia
Autologous Adipose-Derived Stromal Cell Delivered Via Intramuscular Injections for the Treatment of Critical Limb Ischemia
This is an open-label, non-randomized, multi center, patient sponsored study of Adipose-Derived Stromal Cell (ASC) implantation via intramuscular injections in patients who have critical limb ischemia not amenable for…
- Trial name
- NCT02099500
- Testing
- Liposuction, Stem Cell Injection
- Where
- United States
- Sponsor
- Ageless Regenerative Institute
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