Clinical trials: Peripheral Arterial Vascular Occlusion
Foot Ulcers, Arteriosclerosis Obliterans
HELP-Apheresis in Diabetic Ischemic Foot Treatment (H.A.D.I.F)
Diabetic foot (DF) is a common, severe and costly complication of diabetes. DF is underlied by neuropathy, atherosclerosis of distal arteries and infection, which result in tissue ulcers and necrosis.
- Conditions
- Foot Ulcers, Arteriosclerosis Obliterans, Diabetes Mellitus
- Trial name
- HADIF (NCT01518205)
- Testing
- LDL-apheresis
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Universita di Verona
Peripheral Arterial Disease
The Role of HSP90 in Peripheral Vascular Lesions of Diabetic Atherosclerosis
Diabetic foot disease with a global incidence of about 6% is one of the most serious complications of diabetes, which brings great pain and economic burden to patients.In China, the incidence rate is 8.1%, and the amputation rate…
- Trial name
- rhsppvlda (NCT04787770)
- Testing
- non-intervention
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Peripheral Arterial Disease, Atherosclerosis Obliterans
Comparison of 3 Ultrasonic Techniques for Measuring the Systolic Pressure Index
Continuous Doppler ankle brachial index (ABI) is the gold standard for screening and monitoring of peripheral arterial disease (PAD) but is no longer carried out in clinical practice.
- Conditions
- Peripheral Arterial Disease, Atherosclerosis Obliterans, Atherosclerosis Right Leg, Atherosclerosis Left Leg
- Trial name
- ABIPULSE (NCT04440072)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Caen
Peripheral Arterial Disease
Angioplasty + SBCV vs. Angioplasty Alone for Femoropopliteal Artery Stenosis
The purpose of this study is to compare balloon angioplasty plus SBCV against balloon angioplasty alone for treatment of stenosis within the femoropopliteal artery.
- Trial name
- SHIELD (NCT02568293)
- Testing
- SBCV, Saline
- Where
- 8 sites in Australia, New Zealand
- Volunteers
- 66 people
- Sponsor
- Symic Vascular
Chronic Obstructive Pulmonary Disease (COPD)
Effect of Rosuvastatin Therapy in Patients With Stable Chronic Obstructive Pulmonary Disease
The purpose of this study is to investigate whether rosuvastatin improves measures of endothelial function, decreases measures of inflammation, and improves pulmonary function in patients with stable chronic obstructive pulmonary…
- Trial name
- RODEO (NCT00929734)
- Testing
- Rosuvastatin
- Where
- Norway
- Volunteers
- 99 people
- Sponsor
- University Hospital, Akershus
Tobacco Cessation, Peripheral Artery Disease
Onsite Tobacco Cessation Treatment for Patients With PAD
Tobacco cessation treatment is needed for individuals with peripheral artery disease (PAD) to improve symptoms, lower cardiovascular risk, and prevent amputation.
- Trial name
- PAD (NCT05469698)
- Testing
- Tobacco Treatment Research Program Standard Care
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Vitamin D Deficiency, Coronary Artery Disease
Vitamin D Repletion in Coronary Artery Disease
Vitamin D (Vit D) status is an emerging risk marker of great interest in cardiovascular disease (CVD). Lower serum levels of Vit D are associated with both cardiac risk factors and prevalent cardiovascular disease.
- Conditions
- Vitamin D Deficiency, Coronary Artery Disease, Endothelial Dysfunction, Inflammation
- Trial name
- NCT01570309
- Testing
- Ergocalciferol, Sugar pill
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- Seth I. Sokol, M.D.
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Peripheral Artery Disease
REGistry of Long-term AnTithrombotic TherApy-1
To assess the rates of ischemic and hemorrhagic complications of long-term antithrombotic therapy in patients with chronic coronary syndromes
- Trial name
- REGATTA-1 (NCT04347200)
- Testing
- Antiplatelet Drug
- Where
- Russia
- Volunteers
- 2,000 people
- Sponsor
- National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
Peripheral Artery Disease
A Study of Below The Knee Arteries' Stenosis or Occlusion Treated With LEGFLOW OTW
To evaluate the safety and efficacy of the Paclitaxel Releasing Peripheral Balloon Dilatation Catheter (LEGFLOW) compared to the PTA catheter (AMPHIRION DEEP) in treatment of stenosis or occlusion in below the knee artery.
- Trial name
- NCT02962232
- Testing
- Paclitaxel Releasing Peripheral Balloon Dilatation Catheter, PTA catheter
- Where
- 19 sites in China
- Volunteers
- 172 people
- Sponsor
- ZhuHai Cardionovum Medical Device Co., Ltd.
Critical Limb Ischemia, Peripheral Arterial Disease
Chelation Therapy in Diabetic Patients With Critical Limb Ischemia
This is a Pilot Trial Using Chelation Therapy for Limb Preservation in Diabetic Patients with Critical Limb Ischemia.
- Trial name
- TACT-PAD (NCT03424746)
- Testing
- disodium EDTA
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Mt. Sinai Medical Center, Miami
Peripheral Artery Diseases
Detour2 Continued Access Study
Prospective, single-arm, multi-center, clinical investigation to continue to evaluate the safety and effectiveness of the PQ Bypass System to access, deliver guidewires, and implant stent grafts for a percutaneous femoropopliteal…
- Trial name
- NCT04625660
- Testing
- PQ Bypass System
- Where
- 3 sites in United States
- Volunteers
- 11 people
- Sponsor
- Endologix
Peripheral Arterial Disease
Efficacy Evaluation of Dotarem Compared to Gadovist in the Diagnosis of Peripheral Arterial Disease
This study is an efficacy evaluation of Dotarem®-enhanced magnetic resonance angiography (MRA) compared to Gadovist®-enhanced MRA in the diagnosis of clinically significant abdominal or lower limb arterial diseases.
- Trial name
- DALIA (NCT01026389)
- Testing
- Dotarem, Gadovist
- Where
- Austria
- Volunteers
- 189 people
- Sponsor
- Guerbet
Acute Myocardial Infarction, Peripheral Artery Disease
Vastmanland Myocardial Infarction Study (VaMIS)
The main purposes of this study are: to describe the prevalence of peripheral artery disease (including lower extremity artery disease, carotid artery disease, renal artery disease, and abdominal aortic disease) in patients with…
- Conditions
- Acute Myocardial Infarction, Peripheral Artery Disease, Diabetes
- Trial name
- VaMIS (NCT01452178)
- Where
- Sweden
- Volunteers
- 1,008 people
- Sponsor
- Uppsala University
Diabetic Foot Ulcers
Registry HBOT in DFU
Overview of available data to assess the benefits of HBOT to DFU patients
- Trial name
- NCT06693180
- Testing
- HBOT
- Where
- Netherlands
- Volunteers
- 600 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Peripheral Artery Disease
Verizon mHealth Solution for Patients With Peripheral Artery Disease (PAD)
The purpose of this study is to understand the effects that a three month lifestyle-based mobile health (mHealth) peripheral artery disease (PAD) prevention program will have on improving physical activity, fitness, important PAD…
- Trial name
- NCT02472561
- Testing
- Fitbit Physical Activity Monitor, mHealth Glucometer, mHealth Blood Pressure
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Duke University
Peripheral Arterial Disease, Vascular Surgery
Remote Ischemic Preconditioning Prior to Vascular Surgery
The investigators have previously shown that elective vascular surgery is a high-risk operation with an anticipated risk of either death or heart attack of 15%.
- Trial name
- CRIPES (NCT01558596)
- Testing
- Preconditioning, Control
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- VA Office of Research and Development
Critical Limb Ischemia, Peripheral Artery Disease
Safety & Feasibility Study of Tack-It Device for Vessel Dissection Repair
The study is intended to evaluate the safety and feasibility of using the Intact Vascular (Innovasc) Tack-It Endovascular Dissection Repair System (Tack Intravascular Staple System) in patients with vascular flaps in the…
- Trial name
- NCT02044003
- Testing
- Innovasc Tack Intravascular Staple System (Tack)
- Where
- 2 sites in Paraguay
- Volunteers
- 11 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Critical Limb Ischemia, Peripheral Artery Disease
Tolerability and Efficacy of Intravenous Infusion of Autologous MSC_Apceth for the Treatment of Critical Limb Ischemia
MSC_Apceth are GMP-manufactured, autologous ex-vivo expanded non-hemapoietic bone-marrow derived stem cells for the treatment of Critical Limb Ischemia
- Trial name
- NCT01351610
- Testing
- PTA + Infusion of MSC_Apceth, PTA
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Apceth GmbH & Co. KG
Peripheral Arterial Disease
Ankle Arterial Doppler Waveform Assessment For Surveillance Following Lower Limb Revascularisation
The goal of this observational study is to determine the diagnostic performance of serial ankle arterial Doppler waveform assessments in detecting significant arterial restenosis in patients with Peripheral Arterial Disease (PAD)…
- Trial name
- WAVE (NCT06619223)
- Testing
- Duplex Ultrasound
- Volunteers
- 121 people
- Sponsor
- Imperial College London
Peripheral Artery Disease
Clinical Outcomes of Three Different Percutaneous Revascularization Strategies for the Treatment of Lifestyle Limiting Claudication: A Retrospective Analysis
To determine the effect of three different percutaneous revascularization strategies (Balloon Cryoplasty vs. Stent Placement vs. Atherectomy) in the treatment of lifestyle limiting lower extremity claudication
- Trial name
- FIX-IT Retro (NCT00512720)
- Where
- United States
- Volunteers
- 355 people
- Sponsor
- Corewell Health West
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