Clinical trials: Peripheral Arterial Vascular Occlusion
Peripheral Artery Disease
Framing Clinical Trial Enrollment for Patients With Peripheral Artery Disease
It is uncertain whether opt-out framing will increase participation in a clinical trial intended to promote physical activity in patients with peripheral artery disease (PAD).
- Trial name
- NCT04536038
- Testing
- Opt-out
- Where
- United States
- Volunteers
- 5,176 people
- Sponsor
- University of Pennsylvania
Peripheral Arterial Disease, Claudication, Intermittent
SFA TReatment and vAscular Functions
Endovascular treatment of the superficial femoral artery has a high initial success rate, but restenosis occurs in up to 60% of cases.
- Trial name
- STRAtiFy (NCT03811925)
- Testing
- Angioplasty and drug coated balloon of the superficial femoral artery (SFA), Angioplasty and stenting of the superficial femoral artery (SFA)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Essen
Peripheral Artery Disease, Femoropopliteal Artery Occlusion
LEVANT 2 Safety Registry
The primary objective of the LEVANT 2 Extended Follow-up Post-Approval Study (PAS 1) is to evaluate the long-term performance of the Lutonix Drug Coated Balloon (DCB) versus Percutaneous Transluminal Balloon Angioplasty (PTA) in…
- Conditions
- Peripheral Artery Disease, Femoropopliteal Artery Occlusion, Femoropopliteal Stenosis
- Trial name
- NCT01790243
- Testing
- Lutonix Drug Coated Balloon, Standard PTA Balloon
- Where
- 8 sites in United States
- Volunteers
- 1,189 people
- Sponsor
- C. R. Bard
Abdominal Aortic Aneurysm, Coronary Heart Disease
Ethnicity and Onset of Cardiovascular Disease: A CALIBER Study
Specific cardiovascular diseases, such as stroke and heart attack, have been shown to vary by ethnic group. However, less is known about differences between ethnic groups and a wider range of cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease, Sudden Cardiac Death, Intracerebral Haemorrhage
- Trial name
- NCT02176174
- Volunteers
- 1,068,318 people, healthy volunteers welcome
- Sponsor
- University College, London
Peripheral Arterial Disease, Type II Diabetes Mellitus
Dietary Nitrate and Exercise to Augment Exercise Training Benefits in Subjects With DM+PAD
The hypothesis of this proposal is that in subjects with Type II diabetes mellitus (T2D) and peripheral arterial disease (PAD) with intermittent claudication (IC), regular consumption of a high nitrate supplement which raises…
- Trial name
- DM+PAD (NCT01785524)
- Testing
- Beetroot Juice (Beet-It Stamina Shot) and Exercise Training
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Duke University
Peripheral Arterial Disease
Analysis of Arterial Waveforms and Oxygen Pressure During Supervised Exercise for Peripheral Artery Disease
The goal of this observational study is to assess the evolution of oxygen pressure and arterial waveform during supervised exercise therapy in patients with peripheral arterial disease.
- Trial name
- WAVESUPEX (NCT05818046)
- Testing
- transcutaneous oxygen pressure, Supervised Exercise therapy
- Where
- France
- Volunteers
- 36 people
- Sponsor
- University Hospital, Caen
Peripheral Artery Disease, PAD
Unacylated Ghrelin to Improve FuncTioning in PAD: The GIFT Trial
The GIFT pilot study will investigate the optimal subcutaneous dose and safety of subcutaneously administered unacylated ghrelin in older people with peripheral artery disease (PAD).
- Conditions
- Peripheral Artery Disease, PAD, Peripheral Arterial Disease
- Trial name
- GIFT (NCT03358355)
- Testing
- unacelyated ghrelin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Northwestern University
Peripheral Artery Disease
A Prospective Study of the Bard® LifeStent® Solo Vascular Stent System
The purpose of this study is to assess the deliverability, clinical utility, safety and effectiveness of the 250 mm length size offering of the LifeStent® Vascular Stent.
- Trial name
- REALITY2 (NCT02262949)
- Testing
- LifeStent Vascular Stent
- Where
- 4 sites in Germany
- Volunteers
- 31 people
- Sponsor
- C. R. Bard
Femoropopliteal Disease, Drug Coated Balloon
DCB Outcomes After Non-Compliant Balloon Vessel Preparation With or Without Scoring in Patients With Femoropopliteal Arterial Disease
The aim of this clinical trial is to determine whether vessel preparation with a non-compliant scoring balloon before drug-coated balloon (DCB) angioplasty provides superior procedural and clinical outcomes compared with vessel…
- Conditions
- Femoropopliteal Disease, Drug Coated Balloon, Critical Limb-Threatening Ischaemia, Peripheral Arterial Disease
- Trial name
- DASBAD-NC (NCT07764016)
- Testing
- Non-compliant Plain Balloon angioplasty (PBA), Non-compliant Scoring Balloon Angioplasty (SB)
- Volunteers
- 142 people
- Sponsor
- Marc Sirvent
Peripheral Arterial Disease
Angioplasty + SBCV vs. Angioplasty Alone for Femoropopliteal Artery Stenosis
The purpose of this study is to compare balloon angioplasty plus SBCV against balloon angioplasty alone for treatment of stenosis within the femoropopliteal artery.
- Trial name
- SHIELD (NCT02568293)
- Testing
- SBCV, Saline
- Where
- 8 sites in Australia, New Zealand
- Volunteers
- 66 people
- Sponsor
- Symic Vascular
PAD - Peripheral Arterial Disease, PAD
Distrupt Stiffness Trial
Typical symptoms of PAD include exercise-induced pain in the legs (known as intermittent claudication), which can significantly limit pain-free walking. In more advanced stages, pain may also occur at rest.
- Trial name
- NCT07130526
- Testing
- Intravascular Lithotripsy (IVL) plus DCB, POBA plus DCB
- Where
- 2 sites in Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital, Essen
Peripheral Arterial Disease(PAD)
Korean Vascular Intervention Society Multicenter Registry Study on Outcomes of Endovascular Therapy in Lower Limb Artery Diseases (K-VIS ELLA): (A Retrospective & Prospective Observational Study)
1. Study design: multicenter retrospective and prospective observational study 2. Study Cohort : 1. Retrospective cohort: This cohort retrospectively enrolls patients with lower extremity artery disease who underwent endovascular…
- Trial name
- NCT02748226
- Testing
- endovascular treatment
- Where
- South Korea
- Volunteers
- 12,000 people
- Sponsor
- Yonsei University
Peripheral Artery Disease
Self Selected Exercise Intensity in PAD Patients
Although the benefits of supervised walking training in patients with peripheral arterial disease (PAD) and symptoms of intermittent claudication (IC) are well established, one of the main problems found in this type of protocol…
- Trial name
- NCT04333615
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Nove de Julho
Peripheral Vascular Diseases
Understanding the Genetic Basis of Atherosclerosis and Peripheral Arterial Disease
Atherosclerosis, a condition in which fatty deposits build up along the inner walls of arteries, can occur throughout the body. The purpose of this study is to examine the possible genetic differences that may influence where…
- Trial name
- GenePAD (NCT00380185)
- Where
- 2 sites in United States
- Volunteers
- 1,789 people, healthy volunteers welcome
- Sponsor
- Stanford University
Peripheral Arterial Disease, Clopidogrel, Poor Metabolism of
Aspirin and Thienopyridine Resistance in Peripheral Arterial Disease
This study evaluates the effects of Aspirin and thienopyridine resistance in relation to clinical cardiovascular outcomes as the genetic predictors of, and outcomes associated with aspirin and thienopyridine resistance in…
- Trial name
- NCT03174990
- Where
- United States
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Peripheral Arterial Disease
Artificial Intelligence for Early Detection of Peripheral Artery Disease
The goal of this clinical trial is to test an AI-based screening tool that will help to identify patients at high risk of having undiagnosed peripheral artery disease.
- Trial name
- (AID-PAD) (NCT06505317)
- Testing
- AI-based PAD screening intervention
- Volunteers
- 7,800 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Peripheral Arterial Disease
To Verify the Efficacy and Safety of Rapamycin Coated Peripheral Balloon Catheter in the Treatment of Femoral Popliteal Artery Disease
A prospective randomized trial to validate the efficacy and safety of rapamycin coated peripheral balloon catheter in the treatment of femoral popliteal artery disease.
- Trial name
- NCT05662618
- Testing
- Percutaneous selective arteriography of peripheral arteries
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Shanghai Bomaian Medical Technology Co., Ltd
Peripheral Arterial Disease
Use of Entresto Sacubitril/Valsartan for the Treatment of Peripheral Arterial Disease
This study proposes the use of Entresto (sacubitril/valsartan) to test the effects on pain free walking duration on patients with peripheral arterial disease, a condition caused by decreased blood flow to the muscles in the legs.
- Trial name
- NCT02636283
- Testing
- Entresto
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Minnesota
Critical Limb Ischemia (CLI)
LIFE-BTK PK Sub-study
LIFE-BTK PK is a prospective, single-arm, open-label, non-blinded, non-randomized sub-study of LIFE-BTK Randomized Controlled Trial (NCT04227899), that will enroll approximately 7 subjects in the United States (US) and outside…
- Trial name
- NCT05208905
- Testing
- Esprit BTK Device
- Where
- 5 sites in United States, Australia and 1 more
- Volunteers
- 9 people
- Sponsor
- Abbott Medical Devices
Peripheral Arterial Disease (PAD), Diabete Type 2
Electromagnetic Therapy, Peripheral Vascular Diseases, Diabetes
The goal of this clinical trial was to investigate the efficacy of Low frequency pulsed electromagnetic therapy (LFPEMT) in improving vascular-related quality of life (VQ) and spatiotemporal gait parameters in individuals with…
- Conditions
- Peripheral Arterial Disease (PAD), Diabete Type 2, Gait Abnormality, Quality of Life
- Trial name
- NCT07864805
- Testing
- Low-frequency pulsed electromagnetic therapy plus interval exercise training program
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Ashraf Abdelaal
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