Clinical trials: Peripheral Bypass Surgery
Peripheral Artery Disease, Critical Limb Ischemia
Comparison of Prevena Negative Pressure Incision Management System vs. Standard Dressing After Vascular Surgery
The purpose of this study is to evaluate the effectiveness of negative pressure incision management system (Prevena™ Incision Management System (PIMS) or ActiVAC® with the Prevena™ Dressings (Peel and Place™ or Customizable™)…
- Conditions
- Peripheral Artery Disease, Critical Limb Ischemia, Claudication
- Trial name
- NCT02389023
- Testing
- standard gauze dressing, Prevena Incision Management system
- Where
- 5 sites in United States
- Volunteers
- 242 people
- Sponsor
- University of Vermont Medical Center
Peripheral Vascular Diseases, Arterial Occlusive Diseases
Prevention of Autogenous Vein Graft Failure in Peripheral Artery Bypass Procedures
The purpose of this study is to determine the efficacy of graft pretreatment with the E2F decoy, CGT003, as compared to placebo, on the occurrence of graft failure among patients who receive autogenous vein grafts to treat…
- Conditions
- Peripheral Vascular Diseases, Arterial Occlusive Diseases, Ischemia, Graft Occlusion, Vascular
- Trial name
- NCT00041925
- Testing
- CGT003 (E2F Duplex Decoy)
- Where
- 123 sites in United States, Canada
- Volunteers
- 1,400 people
- Sponsor
- Anesiva, Inc.
Peripheral Arterial Disease
The Value of Supervised Exercise Therapy After Invasive Treatment of Peripheral Arterial Disease
The objective of this study is to investigate what the value is of SET after a radiological or surgical intervention for peripheral arterial disease in the aorto-iliacal, femoro-popliteal and crural segments in comparison with a…
- Trial name
- NETP-extra (NCT00497445)
- Testing
- angioplasty / surgery, Angioplasty / surgery and exercise therapy
- Where
- Netherlands
- Volunteers
- 86 people
- Sponsor
- Atrium Medical Center
Bypass Complications, Disorder of Blood Gas
Difference Between Central and Peripheral Arterial Blood Oxygen Saturation With Different CPB Strategy
Femoro-femoral cardiopulmonary bypass with retrograde perfusion is needed for totally thoracoscopic cardiac surgery. one of the major complication of retrograde perfusion is organ hypoperfusion.
- Trial name
- NCT01698853
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xijing Hospital
Peripheral Arterial Disease
Multi-center Study for Stent Graft System for Peripheral Artery
The utility of GP1101 will be evaluated relative to that of surgical bypass in the treatment of Femoral/Popliteal Arterial Symptomatic Peripheral Arterial Disease.
- Trial name
- VJH11-01 (NCT01575808)
- Testing
- GP1101
- Where
- 15 sites in Japan
- Volunteers
- 133 people
- Sponsor
- W.L.Gore & Associates
Chronic Limb-Threatening Ischemia
Peripheral Bypass Trial for Completion Control
The goal of the study is to identify and validate flow measurement and ultrasound images in patients undergoing vein bypass surgery below-knee and above ankle
- Trial name
- PATENT (NCT06264843)
- Testing
- MiraQ with Transit-Time Flow Measurement (TTFM) and L15 High Frequency Ultrasound (HFUS) probes
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Medistim ASA
Granulocyte Immature Forms, Inflammatory Response Syndrome, Systemic
Bands in Peripheral Blood After Coronary Artery Bypass Grafting With and Without Cardiopulmonary Bypass
Coronary artery bypass graft (CABG) surgery is associated with reperfusion syndrome and activation of inflammatory reaction (SIRS). These are more exaggerated when cardiopulmonary bypass (CPB) is used.
- Trial name
- NCT00563030
- Where
- Poland
- Volunteers
- 44 people
- Sponsor
- Medical University of Gdansk
Peripheral Vascular Disease
The Cook Zilver PTX Drug-eluting Stent Versus Bypass Surgery for the Treatment The Cook Zilver PTX Drug-eluting Stent Versus Bypass Surgery of Femoropopliteal TASC C&D Lesions
The objective of this clinical investigation is to evaluate the early and mid-term outcome (after 6 and 12 months) and the long-term (up to 24 months) outcome of the Zilver PTX paclitaxel-eluting stent (Cook) versus bypass…
- Trial name
- ZILVERPASS (NCT01952457)
- Testing
- Zilver PTX, prosthetic bypass
- Where
- 5 sites in Belgium
- Volunteers
- 220 people
- Sponsor
- Flanders Medical Research Program
Peripheral Arterial Disease, Peripheral Artery Disease
FRAME, External Support for Lower Limb Autologous Grafts
30 patients will be enrolled in a prospective, multi-center, one-arm study, enrolling patients with claudication and chronic limb ischemia scheduled for lower limb venous bypass grafting on clinical grounds with single segment…
- Trial name
- NCT04003480
- Testing
- FRAME
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Vascular Graft Solutions Ltd.
Excessive Amount of Blood / Fluid Transfusion
Blood Transfusions in Coronary Artery Bypass Surgery
The hemolytic product free-hemoglobin (fHb) reduces nitric oxide (NO) bioavailability. The present study aims to establish whether transfusions of stored allogenic blood or intraoperative autologous salvaged blood result in…
- Trial name
- NCT02953951
- Testing
- blood transfusion
- Where
- Italy
- Volunteers
- 95 people
- Sponsor
- Universita di Verona
Peripheral Vascular Disease, Femoral Occlusive Disease
New Anastomotic Device for End to End Vascular Anastomosis in the Treatment of Peripheral Vascular Disease
The medical device "Vascular Join" represents a new anastomotic technology that should reduce the inter-surgeons variability in anastomosis construction and increase the performances in terms of results.
- Conditions
- Peripheral Vascular Disease, Femoral Occlusive Disease, Femoropopliteal Occlusive Disease, Aortoiliac Atherosclerosis
- Trial name
- VJ (NCT01514916)
- Testing
- mechanical anastomosis without suture
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Ab Medica Spa
Anesthesia
Anesthesia and Lymphocytes Apoptosis
Most researches revealed that volatile anesthetic sevoflurane has a more marked cardioprotective effect against ischemia compared with intravenous agent propofol.However, propofol has been suggested to be more benefit for…
- Trial name
- OPCAB (NCT01461551)
- Testing
- Sevoflurane, Propofol, combine of sevoflurane and propofol
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Ruijin Hospital
Varicose Veins, Peripheral Arterial Disease
Availability of Venous Conduits in Patients With Varicose Veins for Arterial Bypass Surgery
Patients with PAD having superficial femoral artery (SFA) occlusion were consecutively enrolled. Demographic data and medical history were taken. Physical examination and duplex ultrasound were performed.
- Trial name
- NCT06332833
- Where
- Russia
- Volunteers
- 285 people
- Sponsor
- Pirogov Russian National Research Medical University
Obesity
Gastric Bypass and Peripheral Activity of the Endocannabinoid System
The aim of the study is to precise the effect of a large amount of weight loss induced by gastric bypass on the endocannabinoid system (plasma and adipose tissue) of morbidly obese patients and to determine the influence of a…
- Trial name
- CCENDO (NCT01003873)
- Testing
- Evaluation of the endocannabinoid system, Biopsy of visceral and peripheral adipose tissue, Evaluation of metabolic parameters
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Peripheral Arterial Disease
Assessment of Bypass Surgery and Balloon Angioplasty Effects in Peripheral Arterial Disease Using Contrast Ultrasound
Contrast ultrasound perfusion imaging (CUPI) is a novel tool for the assessment of muscle perfusion deficits in peripheral arterial disease (PAD).
- Trial name
- NCT00424450
- Testing
- lower limb artery bypass surgery, percutaneous angioplasty (PTA)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Freiburg
Conventional Cardiac Surgery With Bypass
Peripheral Four-wavelength Near-infrared Spectroscopy Measurement: a Comparison Between EQUANOX and O3 in Cardiac Surgery
Near-infrared spectroscopy (NIRS) is a continuous and non-invasive technology that measures regional tissue oxygen saturation (rSO2).
- Trial name
- NIRS-8 (NCT02847273)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Peripheral Arterial Occlusive Disease, Atherosclerosis
Remote Endarterectomy Versus Suprageniculate Femoropopliteal Bypass
The objective of this study is to compare remote superficial femoral artery endarterectomy with suprageniculate bypass surgery in the treatment of long occlusions of the superficial femoral artery.
- Trial name
- REVAS (NCT00566436)
- Testing
- Remote endarterectomy of the superficial femoral artery, Suprageniculate femoropopliteal bypass
- Where
- 4 sites in Netherlands
- Volunteers
- 126 people
- Sponsor
- St. Antonius Hospital
Type 2 Diabetes, Peripheral Vascular Disease
The Effect of a Diabetes Action Team in Patients Post Infrainguinal Bypass Surgery With and Without Diabetes
Diabetes is a very common illness. Approximately 4% of British Columbians have diabetes. However, at least 20% of people admitted to acute care hospitals have diabetes.
- Trial name
- NCT00456105
- Testing
- Subjects with diabetes who plan to undergo elective infrainguinal bypass surgery will receive standard diabetes care by their admitting physician, Subjects with diabetes who plan to undergo elective infrainguinal bypass surgery will receive diabetes care under the direction of the Diabetes Action Team, Subjects without diabetes will have their blood glucose levels monitored while in the hospital
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of British Columbia
Atherosclerotic Ischemic Disease, Critical Limb Ischemia
Efficacy and Safety Comparison of the Open and Endovascular Surgical Methods for the Treatment of Long Atherosclerotic Lesions of the Femoral-popliteal Segment Below the Knee, TASC D in Patients With Critical Limb Ischemia
This is prospective, randomized study. The main objective of the study is to compare the clinical efficacy and safety of two therapies for the treatment of prolonged atherosclerotic lesions of the arteries of the femoropopliteal…
- Conditions
- Atherosclerotic Ischemic Disease, Critical Limb Ischemia, Superficial Femoral Artery Occlusion, Popliteal Artery Occlusion
- Trial name
- NCT04583436
- Testing
- Endovascular recanalization, Open surgery
- Where
- Russia
- Volunteers
- 90 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation