Clinical trials: Peripheral Circulation
Peripheral Artery Disease (PAD), Diabetes Mellitus Type 2
Effect of Diabetic Foot Exercises on Peripheral Vascular Status in Type 2 Diabetes Mellitus Patients
This randomized controlled trial aims to evaluate the effectiveness of diabetic foot exercises on peripheral vascular status among patients with type 2 diabetes mellitus.
- Conditions
- Peripheral Artery Disease (PAD), Diabetes Mellitus Type 2, Diabetic Foot Circulation Impairment
- Trial name
- NCT07262203
- Testing
- Diabetic Foot Exercise Program
- Where
- Indonesia
- Volunteers
- 44 people
- Sponsor
- Universitas Muhammadiyah Surakarta
Sepsis, Critical Illness
Peripheral Perfusion Index Trajectory to Predict 28-Day Mortality in Patients With Sepsis in the Intensive Care Unit
Sepsis is a life-threatening condition caused by the body's overwhelming response to infection, and it remains a leading cause of death in intensive care units.
- Trial name
- PERFUSE-ICU (NCT07740304)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Trakya University
Pediatrics, Anesthesia, Local
Validation of Peripheral Perfusion Index in Predicting Successful Supraclavicular Brachial Plexus Block in Pediatrics
Few data are available for the PI as a tool for evaluation of peripheral block success in pediatric patients. Furthermore, there is currently no cut-off value defined for the accuracy of the PI in the detection of successful…
- Trial name
- NCT05815563
- Where
- Egypt
- Volunteers
- 59 people
- Sponsor
- Cairo University
Peripheral Arterial Disease
Blood Flow Restricted Resistance Training in Peripheral Arterial Disease
A randomised controlled trial evaluating the feasibility and acceptability of a 12 week lower body blood flow restricted resistance exercise programme for people with peripheral arterial disease.
- Trial name
- NCT04890275
- Testing
- Blood flow restricted resistance exercise (BFR), Resistance exercise without blood flow restricted (NON-BFR)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Sheffield Hallam University
Peripheral Perfusion Index, Caudal Block
Peripheral Perfusion Index as an Early Predictor of Successful Caudal Block in Pediatric Patients Undergoing Lower Abdominopelvic Surgeries Under General Anesthesia
The aim of this study is to assess early predictability of peripheral perfusion index to success of caudal block in pediatric patients undergoing lower abdominopelvic surgeries
- Trial name
- NCT06846983
- Testing
- Peripheral perfusion index pulse oximeter
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Restless Legs Syndrome, Neuropathic Pain
Spinal Cord Stimulation for Restless Legs Syndrome
The overall goal of this proposed study is to evaluate the underlying mechanisms of neural control of blood flow in the lower extremities in humans with restless leg syndrome (RLS).
- Trial name
- NCT03539081
- Testing
- Dual-energy X-ray absorptiometry Scan, Laboratory Measurements, Blood Flow Measurement
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Marshall Holland
Peripheral Perfusion, Postoperative Pain
Effects Magnesium Sulfate and Labetalol Infusion on Peripheral Perfusion and Pain in Nasal Surgeries
One of main risk of controlled hypotension during nasal surgeries is impaired perfusion. Peripheral perfusion of non-vital organs usually impaired earlier than vital organs.
- Trial name
- NCT04688203
- Testing
- Magnesium Sulfate Injection, Labetalol Injectable Solution
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Transcatheter Aortic Valve Replacement, Mechanical Circulatory Support
Application of Emergent Peripheral Mechanical Circulatory Support in Transcatheter Aortic Valve Replacement for 6 Patients
Objective: To explore the experience of transcranial aortic valve replacement (TAVR) under emergency mechanical assisted circulation (MCS).Methods: A total of 6 patients who completed TAVR with the assistance of emergency MCS in…
- Trial name
- NCT04464356
- Testing
- mechanical circulatory support
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Peripheral Arterial Disease, Peripheral Artery Disease
Blood Flow Changes in Femoral-popliteal Bypass Grafts After Neuromuscular Electrical Stimulation (NMES).
The muscles of the leg require a regular supply of oxygen and nutrients. This is supplied by blood carried by a network of large blood vessels known as arteries.
- Conditions
- Peripheral Arterial Disease, Peripheral Artery Disease, Peripheral Vascular Disease, Femoral Popliteal Occlusion
- Trial name
- HAEMUS (NCT04109287)
- Testing
- REVITIVE® device
- Where
- United Kingdom
- Sponsor
- Imperial College Healthcare NHS Trust
Intraoperative Hypotension
PPI Guided Strategies for Prevention and Treatment of Intraoperative Hypotension
Intraoperative hypotension is closely related to the poor prognosis of surgery. The study is focused on the effectiveness of maintaining normal peripheral perfusion index (PPI) on time-weighted average of hypotension during…
- Trial name
- NCT05792696
- Testing
- PPI guided strategies, Empirical strategies
- Where
- China
- Volunteers
- 54 people
- Sponsor
- zhiqiang zhou
Cerebral Oxygenation, Cerebral Blood Flow
Cerebral Near Infrared Spectroscopy During Blood Sampling From a Peripheral Artery Catheter in Preterm Infants
Preterm infants often need peripheral artery catheters for invasive blood pressure recording and to facilitate blood sampling. Near infrared spectroscopy is a method to evaluate cerebral oxygenation and as well as cerebral blood…
- Conditions
- Cerebral Oxygenation, Cerebral Blood Flow, Prematurity
- Trial name
- NCT00926770
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Cologne
Spinal Cord Injury
Blood Flow Restriction Exercise for Those With SCI
Spinal cord injuries (SCI) are among the most debilitating conditions an individual can sustain with the estimates of SCI incidence in the United States at 12,000 new cases per year.
- Trial name
- NCT04889092
- Testing
- Blood Flow Restriction exercise, Traditional resistance exercise
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- VA Office of Research and Development
Anesthesia
Hemodynamics for Equi-MAC Anesthesia
The aim of this study is to compare the peripheral perfusion index values produced by equi-MAC of sevoflurane and desflurane in patients undergoing single-agent inhalation anesthesia.
- Trial name
- NCT03570164
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Kangbuk Samsung Hospital
Peripheral Arterial Disease
Blood Flow Quantification Near Stented SFA Lesions Using Ultrasound Velocimetry
Peripheral arterial disease (PAD) in the lower extremity is the third leading cause of atherosclerotic cardiovascular morbidity. Endovascular treatment has become the principal surgical strategy in femoro-popliteal lesions.
- Trial name
- EchoPIV in SFA (NCT04934501)
- Testing
- High-frame-rate contrast-enhanced ultrasound measurements (echoPIV), Computed tomography angiography (CTA) scan
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Rijnstate Hospital
Type 2 Diabetes Mellitus, Peripheral Microvascular Symptoms
The Effect of Prostaglandin I2 on the Endothelial Cell Function Disorder in Type 2 Diabetes Mellitus Patients
This study attempts to examine the effect of oral prostaglandin I2 (Beraprost Na), administered for eight weeks, on the endothelial cell functional disorder among asymptomatic high risk diabetes mellitus patients.
- Trial name
- NCT01061060
- Testing
- Prostaglandin I2
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Yonsei University
Shock, Cardiogenic, Cardiac Arrest
Hemodynamic Comparison of Peripheral and Central VA ECMO.
The goal of this clinical trial is to monitor hemodynamic differences between central veno-arterial extracorporeal membrane oxygenation (VA ECMO) and peripheral VA ECMO.
- Conditions
- Shock, Cardiogenic, Cardiac Arrest, Extracorporeal Circulation; Complications, Hemodynamics Instability
- Trial name
- RECOVERY (NCT05669183)
- Testing
- Veno-arterial extracorporeal membrane oxygenation
- Where
- China
- Volunteers
- 136 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Chest Wall Blocks
Serratus Anterior Plan Block (SAP) and Pectoralis (PECSI-II) Blocks on Left Internal Mammarian Artery (LIMA) Blood Flow
To investigate whether the anterior chest wall blocks performed before the surgery have an effect on the LIMA (left internal mammarian artery) blood flow in patients who will undergo coronary artery bypass surgery.
- Trial name
- NCT05907798
- Testing
- LIMA Blood flow
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Cold Exposure
The Effects of Cold Adaptation on Skin Blood Flow, Hand Function, and Comfort in Healthy Adults
In cold weather environments, blood flow to the extremities is significantly reduced, which severely impairs hand function and induces thermal discomfort.
- Trial name
- NCT05464758
- Testing
- Repeated cold exposure
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Peripheral Arterial Disease, Peripheral Vascular Disease
Evaluation of the Safety and Efficacy of a Vascular Prosthesis as an Above-Knee Bypass Graft in Patients With PAD
The purpose of this study is to assess the safety and efficacy of a novel, tissue-engineered vascular prosthesis, the Human Acellular Vessel (HAV).
- Trial name
- NCT01872208
- Testing
- HAV implantation
- Where
- 3 sites in Poland
- Volunteers
- 20 people
- Sponsor
- Humacyte, Inc.
Acute Circulatory Failure
Peripheral Tissue Perfusion in Intensive Care
Tissue perfusion has been identified as an early prognosis factor in patients admitted to intensive care. However, little is known about the effects of different hemodynamic interventions performed in clinical routine on…
- Trial name
- INPPEREA (NCT06384287)
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris