Clinical trials: Peripheral Circulation
Anesthesia, Peripheral Arterial Diseases
The Effect of Blood Pressure on Cerebral Perfusion During Vascular Surgery
Anesthesia reduces blood pressure and cerebral blood flow is normally considered to be maintained despite marked changes in blood pressure.
- Trial name
- NCT02531139
- Testing
- MAP maintained at 80 mmHg, MAP maintained at 60 mmHg
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Diabetic Peripheral Neuropathy (DPN)
Administrative Claims Analysis of Metanx® in Diabetic Peripheral Neuropathy
This study will be an observational cohort study utilizing administrative claims data with 100 patients randomly selected taking Metanx® meeting the inclusion and exclusion criteria and 400 propensity score matched patients…
- Trial name
- NCT01247558
- Testing
- Metanx® (a medical food), Not treated with Metanx®
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Pamlab, L.L.C.
Monitoring, Physiological
Perfusion Index in Anesthesia
In patients under general anesthesia the investigators wish to investigate association and covariance between a peripheral perfusion index as obtained by Radical 7 monitor (Masimo, Irvine, CA, USA) and more traditional…
- Trial name
- NCT02989441
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Jakob Højlund
Septic Shock, Hyperlactatemia
Peripheral Perfusion Versus Lactate Targeted Fluid Resuscitation in Septic Shock
Persistent hyperlactatemia has been traditionally considered as representing tissue hypoxia, and lactate normalization is recommended as a resuscitation target by the Surviving Sepsis Campaign (SSC).
- Conditions
- Septic Shock, Hyperlactatemia, Peripheral Perfusion
- Trial name
- NCT03762005
- Testing
- CRT guided resuscitation, Lactate guided resuscitation
- Where
- Chile
- Volunteers
- 46 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Peripheral Artery Disease
Technical Development of Cardiovascular Magnetic Resonance Imaging
The goal of this study is to develop advances in cardiovascular diagnostic and treatment methods using magnetic resonance imaging (MRI), a test that uses a strong magnetic field and radio waves to show anatomic detail.
- Trial name
- NCT00064896
- Testing
- MRI
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Diabetic Ketoacidosis
Perfusion Index for Predicting Diabetic Ketoacidosis Severity in the Emergency Department
This prospective observational cohort study will evaluate whether the perfusion index measured at emergency department admission is associated with the severity of diabetic ketoacidosis in adults.
- Trial name
- NCT07820371
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ankara Etlik City Hospital
Diabetic Peripheral Neuropathy, Diabetic Peripheral Neuropathic Pain
Exercise Induced Hypoalgesia Diabetes
The purpose of this research study is to learn whether different forms of exercise can reduce pain experienced by individuals with painful diabetic peripheral neuropathy.
- Trial name
- EIHDM (NCT05296642)
- Testing
- Moderate Cycling, Personalized Tourniquet System
- Where
- United States
- Sponsor
- University of Miami
Critical Illness, Low Peripheral Perfusion
Local Warming to Improve Pulse Oximetry Accuracy in Critically Ill Patients
Pulse oximeters are widely used in intensive care to continuously estimate the oxygen level in the blood. However, pulse oximeter measurements may be less accurate when blood flow to the fingers is poor, which is common in…
- Conditions
- Critical Illness, Low Peripheral Perfusion, Pulse Oximetry Accuracy
- Trial name
- PULSEWARM (NCT07792304)
- Testing
- Protocolized Local Warming
- Where
- 4 sites in Sweden
- Volunteers
- 240 people
- Sponsor
- Vastra Gotaland Region
Arterial Stiffness, Magnetic Field Exposure
Assessing Impacts of Static Magnetic Fields on Peripheral Pulses and Skin Blood Flow
The purpose of this research study is to investigate and determine the effects of static magnetic fields produced by a small magnet on peripheral pulses and skin blood flow.
- Conditions
- Arterial Stiffness, Magnetic Field Exposure, Peripheral Arterial Disease
- Trial name
- NCT04539704
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Obstructive Sleep Apnea
Inorganic Nitrate and OSA
The main purpose of this study is to determine if acute beetroot juice supplementation reduces peripheral chemoreflex sensitivity in patients with obstructive sleep apnea.
- Trial name
- NCT03930563
- Testing
- Pre-beetroot juice supplementation, Post-beetroot juice supplementation
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Heart Failure
Interval Versus Continuous Training in Heart Failure
BACKGROUND: The physiopathology of the heart failure involves compensatory mechanisms as exacerbated neurohormonal activity, endothelial dysfunction and consequently the muscle disability and exercise intolerance.
- Trial name
- NCT02448147
- Testing
- Interval training, Continuous training
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Pulmonary Arterial Hypertension
Peripheral Muscle Microcirculation and Exercise-induced Blood Flow Distribution in Pulmonary Arterial Hypertension
Pulmonary artery hypertension (PAH) is a rare, severe disease, characterized by a progressive increase in pulmonary vascular resistance ultimately leading to right ventricular (RV) failure and premature death.
- Trial name
- NCT01520493
- Testing
- Submaximal exercises
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Laval University
Peripheral Perfusion Index
Predictor of Postoperative Complications After Lengthy Noncardiac Surgery
Many patients undergoing long time surgery will manifest increased level of blood lactate. Hyperlactacidemia can cause disturbance of internal environment, then leading to increased complications and longer ICU stay, even death.
- Trial name
- complication (NCT04680663)
- Testing
- Peripheral Perfusion index, serum lactate level
- Where
- Egypt
- Volunteers
- 235 people
- Sponsor
- Cairo University
Decreased Vascular Flow
Interferential Electrical Stimulation and Vasodilatation in Healthy Individuals
Interferential electrical stimulation (IES) increases local blood flow. It is not known whether increases in blood flow may be caused by inhibition of sympathetic activity, mediated by muscle metaboreflex activity.
- Trial name
- InterM (NCT01450371)
- Testing
- Interferential
- Where
- 3 sites in Brazil
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Respiratory Distress Syndrome
Effects of Bolus Surfactant Therapy on Peripheral Perfusion Index and Tissue Carbon Monoxide
Exogenous bolus surfactant administration may affect hemodynamic parameters and peripheral perfusion. Surfactant therapy is commonly used for respiratory distress syndrome in premature infants, which is also associated with…
- Trial name
- NCT01923844
- Testing
- exogenous surfactant
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ege University
Obesity
Peripheral Vasodilation in Obese Humans
The growing population of obese adults is predicted to create a large public health burden in the next few decades. This study examines function of small blood vessels providing blood flow to skeletal muscles, to test if younger…
- Trial name
- ObeseDilate (NCT02833207)
- Testing
- Drug Trial 1 (EDD), Drug Trial 2 (ROV)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Fracture of Hip, Ileus
Peripheral Perfusion Index in Acute Surgical Patients
Introduction Perioperative haemodynamic instability is associated with postoperative morbidity and mortality. Macrocirculatory parameters, such as the conventionally obtained mean arterial blood pressure and cardiac output, may…
- Conditions
- Fracture of Hip, Ileus, Perforated Viscus, Anastomotic Leak
- Trial name
- NCT03757442
- Where
- Denmark
- Volunteers
- 1,338 people
- Sponsor
- Hvidovre University Hospital
Circulatory Failure
ASSESSment of Perfusion, Oxygen Saturation, Endothelial Function and Coagulation in Circulatory SHOCK
The objective of the observational cohort study is (1) to deduce whether measurements of peripheral near-infrared spectroscopy (NIRS) (lower limb) associate with the development of organ dysfunction as assessed by daily…
- Trial name
- ASSESS-SHOCK (NCT03814564)
- Testing
- NIRS monitoring
- Where
- 3 sites in Finland
- Volunteers
- 325 people
- Sponsor
- Helsinki University Central Hospital
Raynaud's Disease
Nova Cold Hands Raynaud's Disorder, a Disease Which Results in Decreased Blood Flow to the Hands and Feet.
Patients presenting to UIC rheumatology clinic with Raynaud's disorder and scleroderma will be asked to participate. 10 hands of patients with both Raynaud's disorder and scleroderma will be studied.
- Trial name
- NCT02615964
- Testing
- Nova Flow Procedure
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Breast Neoplasm
Preventing Chemotherapy-induced Peripheral Neuropathy Using PRESIONA Exercise Program
The aim of this study is to determinate if therapeutic exercise with blood flow restriction (BFR) during neoadjuvant chemotherapy potentialy neurotoxic could prevent the onset of chemotherapy induced peripheral neuropathy (CIPN)…
- Trial name
- PRESIONA (NCT04652609)
- Testing
- PRESIONA
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Universidad de Granada