Clinical trials: Peripheral Nerve Block, open to volunteers
Cerebral Palsy, Postoperative Pain
Combined Popliteal and Adductor Canal Blocks for Postoperative Analgesia in Children With Cerebral Palsy
This prospective, randomized, controlled trial aims to evaluate the postoperative analgesic efficacy of combined ultrasound-guided popliteal sciatic nerve block and adductor canal block in children with cerebral palsy undergoing…
- Trial name
- NCT07801365
- Testing
- Adductor Canal Block + Popliteal Sciatic Nerve Block Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Sciatica Acute
Comparing Ultrasound-Guided Transgluteal Nerve Block to Standard Care
The goal of this clinical trial is to compare transgluteal sciatic nerve block to standard of care to treat sciatic back pain in adult patients who present to the emergency department.
- Trial name
- TGSNB vs SoC (NCT07397117)
- Testing
- nerve block with ropivacaine, Standard medical treatment
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Melanoma
Effects of Anti-PD1 Adjuvant Checkpoint Blockade Immunotherapy on Atypical/Dysplastic Nevi
This study will examine the impact of anti-programmed cell death 1 (PD1) therapy given in the approved adjuvant therapeutic regimens upon the morphologic, histopathologic, molecular and immunologic as well as genomic features of…
- Trial name
- NCT06599619
- Testing
- Single agent, adjuvant anti-PD1 therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- John Kirkwood
Postoperative Pain, Rebound Pain
Nerve Block Resolution Time Display and Pain Complaints
This randomized prospective study will evaluate whether displaying the expected nerve block resolution time on a patient's splint reduces postoperative pain-related complaints after orthopedic surgery.
- Conditions
- Postoperative Pain, Rebound Pain, Fracture
- Trial name
- NCT07887516
- Testing
- Physical display
- Volunteers
- 128 people
- Sponsor
- Medical University of South Carolina
Pain Syndrome, Pain Management
Peripheral Neurostimulation for Nerve Block Placement
Peripheral nerve blocks are routinely used and highly successful for intra-operative anesthesia and post-operative pain management.
- Trial name
- NCT06566664
- Testing
- B Braun HNS 12 nerve stimulator
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Stanford University
Acute Pain, Chronic Post Operative Pain
Understanding the Acute Pain Phenotype in Patients Undergoing Surgery
The goal of this observational study is to learn about how regional anesthesia (numbing medication) affects pain in patients with different psychosocial phenotypes such as different levels of concern about pain, sleep issues, and…
- Conditions
- Acute Pain, Chronic Post Operative Pain, Opioid Use
- Trial name
- NCT06466941
- Testing
- regional anesthesia, no regional anesthesia, acute pain consultation
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Brigham and Women's Hospital
Post Operative Analgesia, Rebound Pain
Prevention of Rebound Pain After Orthopaedic Surgery With Peripheral Nerve Block (REBOUND)_part A
Rebound pain after peripheral nerve blocks reduces the benefits of regional anesthesia and increases opioid consumption. This rebound pain most likely results from suboptimal pain management, as patients receiving a peripheral…
- Conditions
- Post Operative Analgesia, Rebound Pain, Post Operative Pain, Acute
- Trial name
- REBOUND (NCT07666971)
- Testing
- Morphine provided via oral PCA, Morphine provided via oral PCA + morphine administered at a scheduled regimen
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Postoperative Pain Following Knee Arthroplasty
The Effect of Distal Versus Proximal iPACK on Pain After Total Knee Arthroplasty
Total knee arthroplasty (TKA) often results in significant postoperative pain, which can hinder recovery despite advances in surgical and anesthetic techniques.
- Trial name
- eDIPACK (NCT07080892)
- Testing
- distal iPACK, proximal iPACK
- Where
- Slovakia
- Volunteers
- 120 people
- Sponsor
- Comenius University
Fractures, Hip, Femoral Neck Fractures
Preoperative Use of Peripheral Nerve Blocks in Elderly Patients With Hip Fractures
The goal of this clinical trial is to explore the effects of different peripheral nerve blocks in older adults with hip fractures. It will also explore the safety of preoperative administration of peripheral nerve blocks.
- Conditions
- Fractures, Hip, Femoral Neck Fractures, Intertrochanteric Fractures, Subtrochanteric Fractures
- Trial name
- NCT07130006
- Testing
- PENG and LFCN peripheral nerve blocks with spinal anesthesia, FN and LFCN peripheral nerve blocks with spinal anesthesia, FIC peripheral nerve block with spinal anesthesia
- Where
- Croatia
- Volunteers
- 256 people
- Sponsor
- University Hospital of Split
Chronic Pain, Cancer Pain
UDOPAL Study: Home-Based Interventional Approach to Pain Management in Home-Hospitalized Patients
The UDOPAL Study proposes an innovative home-based care approach for the management of pain in patients admitted to the Home Hospitalization Unit (UHD).
- Conditions
- Chronic Pain, Cancer Pain, Neuropathic Pain, Palliative Care
- Trial name
- UDOPAL (NCT07265492)
- Testing
- UDOPAL model
- Volunteers
- 100 people
- Sponsor
- Hospital de Manises
Postamputation Pain, Lower Limb Amputation
Acute Post-Amputation Pain Management After Combat-Related Lower Limb Injury
Acute post-amputation pain remains a significant clinical challenge in patients with combat-related lower limb injuries and may negatively affect early rehabilitation, mobility, and opioid consumption.
- Conditions
- Postamputation Pain, Lower Limb Amputation, Combat Trauma
- Trial name
- APAPMACRLLI (NCT07863921)
- Testing
- Continuous Peripheral Nerve Blocks, Peripheral Nerve Cryoablation, Standard multimodal analgesia
- Where
- Ukraine
- Volunteers
- 36 people
- Sponsor
- Kharkiv National Medical University
Supraclavicular Plexus Block, Ultrasound
Ultrasound-Guided Supraclavicular Block With vs Without PNS
Peripheral Nerve Blockade (PNB) became reliable with the advent of Ultrasound (US) and Peripheral Nerve Stimulation (PNS). US offers real-time visualization but has limitations, especially with deep or obscured nerves.
- Conditions
- Supraclavicular Plexus Block, Ultrasound, Anaesthesia
- Trial name
- NCT07083934
- Testing
- Peripheral nerve stimulator, No peripheral nerve stimulator
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Painful Diabetic Neuropathy, Neuropathic Pain
Peripheral Nerve Block in Patients With Painful Diabetic Polyneuropathy
The purpose of the present study is to evaluate the role of peripheral afferent input for spontaneous pain in painful diabetic polyneuropathy
- Conditions
- Painful Diabetic Neuropathy, Neuropathic Pain, Neuropathy;Peripheral
- Trial name
- NCT04699734
- Testing
- Xylocaine 1%, NaCl 9mg/ml
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- University of Aarhus
Renal Transplantation, Peripheral Nerve Block
Comparison of the Analgesic Effects of TFPB in Renal Transplantation Surgery
Renal transplantation is a major surgical procedure associated with significant postoperative pain, particularly due to lower abdominal incision, deep tissue dissection, and extensive surgical manipulation.
- Conditions
- Renal Transplantation, Peripheral Nerve Block, Pain Management
- Trial name
- NCT07542028
- Testing
- Transversalis Fascia Plane Block Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara Etlik City Hospital
Hypertension, Retroperitoneal Disease
Clinical Analysis of the Antihypertensive Effect of Laparoscopic Peripheral Nerve Blockade of the Renal Artery in Patients With Retroperitoneal Disease and Hypertension
The primary objective of this study is to evaluate the efficacy and safety of laparoscopic renal artery nerve blockade surgery in patients with retroperitoneal diseases complicated by hypertension.
- Trial name
- NCT06829134
- Testing
- laparoscopic renal artery perivascular nerve blockade, surgery related to the primary disease
- Where
- China
- Volunteers
- 246 people
- Sponsor
- Ruijin Hospital