Clinical trials: Peripheral Nerve Disorder
Type 1 Diabetes, Hypertension
Study of 24 Hour Blood Pressure and the Association to Complications to Type 1 Diabetes
The aim of the study is to evaluate the prevalence of abnormal nocturnal blood pressure (BP) in patients with type 1 diabetes. The investigators wish to gain knowledge on the relation between central and peripheral 24 hour BP and…
- Trial name
- PROFIL (NCT01171248)
- Where
- Denmark
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
Ulnar Neuropathies
The Effect of Perineural Dextrose Injection in Patients With Ulnar Neuropathy at the Elbow
Ulnar neuropathy at the elbow (UNE) is the second most common neuropathy and occurs after recurrent or elongated elbow flexion. Diagnosis of UNE depends on clinical symptoms, physical examination, and electrophysiological…
- Trial name
- NCT03737916
- Testing
- 5 cc 5% Dextrose solution, 5 cc salin
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Education and Research Hospital
Carpal Tunnel Syndrome (CTS)
Correlation Between Forward Head Posture, Cervical Range of Motion, and Nerve Conduction Values in Carpal Tunnel Cases
Before the examination, participants underwent thorough preparation to guarantee the accuracy and reliability of the study's results.
- Trial name
- FHPCTS (NCT06942052)
- Where
- Egypt
- Volunteers
- 119 people
- Sponsor
- Cairo University
Lumbar Radiculopathy
The Effect of Transcranial Magnetic Stimulation Therapy in Patients With Lumbar Radiculopathy
The present study aims to investigate the efficacy of repetitive transcranial magnetic stimulation of the motor cortex combined with transforaminal epidural steroid injection in patients with chronic lumbar radiculopathy.
- Trial name
- NCT04212949
- Testing
- Repetitive transcranial magnetic stimulation (rTMS), Transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Marmara University
Cerebral Palsy (CP), Spastic Paraplegia
Retrospective Study on the WalkOn AFO in Children or Teenagers With Neurological Pathologies
The goal of this observational study is to assess the interest of prefabricated carbon fiber ankle foot orthoses (AFO) in children and teenagers with central or peripheral neurological pathologies.
- Conditions
- Cerebral Palsy (CP), Spastic Paraplegia, Spinal Cord Injuries (SCI), Spina Bifida
- Trial name
- NCT06740006
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Otto Bock France SNC
Chemotherapy-induced Peripheral Neuropathy
Photobiomodulation Therapy in the Management of Chemotherapy-Induced Peripheral Neuropathy
This study aims to investigate the effectiveness of photobiomodulation therapy (PBM) in the management of chemotherapy-induced peripheral neuropathy (CIPN).
- Trial name
- NeuroLight 2 (NCT05763706)
- Testing
- Multiwave Locked System® (M6 laser, ASA srl, Arcugnano (VI), Italy)
- Where
- Belgium
- Volunteers
- 172 people
- Sponsor
- Jessa Hospital
Sciatica
Ultrasound-guided Caudal or Interlaminar Corticosteroid Epidural Injection for Sciatica
An open-label randomized trial to compare the efficacy of ultrasound-guided caudal and interlaminar corticosteroid injections for the treatment of lumbar disk herniation-related sciatica.
- Trial name
- HiatUS (NCT02897336)
- Testing
- ultrasound-guided, interlaminar
- Where
- France
- Sponsor
- University Hospital, Caen
Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer
Efficacy of Auricular Acupuncture Therapy in the Prevention of CIPN in Breast Cancer
Evaluate the Efficacy of Auricular Acupuncture Therapy via the Seirin Pyonex Needles in the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer
- Trial name
- NCT07092111
- Testing
- Auricular acupuncture treatment
- Where
- China
- Volunteers
- 110 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Neuropathy;Peripheral, Limb Ischemia
Feasibility and Clinical Utility of Paired Non-Invasive Hemodynamic and Tissue Oximetry Monitoring to Detect Limb Ischemia in Lithotomy-Positioned Surgeries
The LIMB Study is a prospective, observational pilot study evaluating the feasibility of combined non-invasive hemodynamic and lower-limb tissue oximetry monitoring during prolonged minimally invasive pelvic surgeries performed…
- Trial name
- LIMB (NCT07387653)
- Testing
- Lower-Extremity Perfusion Monitoring
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Earache
Interest of Pregabalin (Lyrica) on the Treatment of Reflex Earache in Head and Neck Cancer.
Referred otalgia is one of the symptoms of oropharynx and hypopharynx cancer. It can be primary (otodynia) or secondary (referred otalgia and projected pain).
- Trial name
- LYRORL (NCT02924675)
- Testing
- Pregabalin
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Lille
Complex Regional Pain Syndromes
Comparison of Volumes of Local Anesthetics on the Efficiency and Safety of Stellate Ganglion Block for CRPS of the Arm
The purpose of this study is to compare the efficiency and safety of 2ml versus 5ml of local anesthetics used in stellate ganglion blocks for the treatment of complex regional pain syndrome of the arm.
- Trial name
- NCT03316066
- Testing
- stellate ganglion block with ropivacaine 0.2% 5 mL, stellate ganglion block wit ropivacaine 0.2% 2 mL
- Sponsor
- Maisonneuve-Rosemont Hospital
Neuropathic Pain, Neuropathy;Peripheral
The Effect of Lacosamide in Peripheral Neuropathic Pain
The main purpose of this study is to compare the change in pain intensity during treatment with a sodium-channel blocker (lacosamide) in patients with peripheral neuropathic pain with and without the irritable nociceptor…
- Conditions
- Neuropathic Pain, Neuropathy;Peripheral, Neuropathy, Painful, Neuropathy, Diabetic
- Trial name
- NCT03777956
- Testing
- Lacosamide
- Where
- Denmark
- Volunteers
- 63 people
- Sponsor
- Danish Pain Research Center
Cervical Radiculopathy
Ultrasound Guided Transcutaneous Pulsed Radiofrequency for Cervical Radiculopathy
Cervical radiculopathy (CR) is a painful condition caused by irritation of the cervical nerve roots, often leading to neck, shoulder, and arm pain, sometimes with numbness or weakness.
- Trial name
- NCT07207356
- Testing
- true transcutaneous pulsed radiofrequency
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Diabetic Neuropathy, Painful
A Study for Treatment of Pain in Patients With Diabetic Neuropathy.
The purpose of this study is to test whether a new treatment will be safe and effective in treating pain. Patients with diabetic peripheral neuropathy will be included.
- Trial name
- NCT00785577
- Testing
- Pregabalin, LY545694 21 mg, LY545694 49 mg
- Where
- 13 sites in United States, Mexico and 1 more
- Volunteers
- 273 people
- Sponsor
- Eli Lilly and Company
Complex Regional Pain Syndrome, Sciatica
[18F]FTC-146 PET/MRI in Healthy Volunteers and in CRPS and Sciatica
Chronic pain can result from injured or inflamed nerves, as occurs in people suffering from sciatica and CRPS. These nerve injuries or regions of nerve irritation are often the cause of pain in these conditions, but the current…
- Trial name
- NCT02753101
- Testing
- [18F]-FTC-146
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Stanford University
Phantom Limb Pain, Phantom Pain
Study of Phantom Limb Pain Using Peripheral Nerve and Spinal Cord Stimulation
The purpose of this study is to evaluate the effectiveness of neuromodulation for relief of phantom limb pain (PLP) using peripheral nerve (PNS) and spinal cord (SCS) stimulation with implantable electrodes.
- Conditions
- Phantom Limb Pain, Phantom Pain, Amputation
- Trial name
- NCT05650931
- Testing
- Implantation of PNS electrodes during surgery, mapping to select sites with the best effect and pain modulation., SCS electrode implantation at surgery, mapping to select sites with the best effect and pain modulation., EEG to search for phantom pain biomarkers
- Where
- Russia
- Volunteers
- 10 people
- Sponsor
- Artur Biktimirov
Diabetic Neuropathy Peripheral
Effect of High Tone Power Therapy on Neurophysiological Measures and Function Outcome in Patients With Diabetic Neuropathy
The purpose of the study is to investigate the effect of high tone power therapy on neurophysiological measures and function outcome in patients with diabetic neuropathy.
- Trial name
- NCT03888872
- Testing
- High tone power therapy, Selected Physical Therapy Program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- October 6 University
Cancer
Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation
RATIONALE: Giving itraconazole or fluconazole may be effective in preventing infections in patients undergoing peripheral stem cell or bone marrow transplantation.
- Trial name
- NCT00003883
- Testing
- fluconazole, itraconazole
- Where
- 2 sites in United States
- Volunteers
- 578 people
- Sponsor
- Fred Hutchinson Cancer Center
Neuropathic Pain, PTSD
The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD
This study is aimed to evaluate outpatient ketamine infusion within a military chronic neuropathic pain population and its effect on PTSD. Currently, this is a pilot study with 30 participants.
- Trial name
- NCT06414356
- Testing
- Ketamine, Magnesium sulfate, Ketamine + Magnesium sulfate
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Margaux M. Salas, PhD
Pudendal Neuralgia
Evaluation of the Efficacy of Therapeutic Infiltrations of the Pudendal Nerve, Performed Under Neurostimulation on Pain, 1 Month After an Infiltration of Local Anaesthetic, in the Treatment of Pudendal Neuralgia.
Pudendal neuralgia (PN) is a chronic nerve compression syndrome causing neuropathic pain. Treatment includes medication, infiltration and decompressive surgery.
- Trial name
- EPHI-DACI (NCT06872437)
- Testing
- Lidocaine Injectable Solution, Saline Solution for Block
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
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