Clinical trials: Peripheral Nerve Disorder
Vestibular Schwannoma, Neurofibromatosis Type 2
Bevacizumab for Symptomatic Vestibular Schwannoma in Neurofibromatosis Type 2 (NF2)
People who have neurofibromatosis type 2 (NF2) can have tumors that grow on the auditory nerves and cause hearing loss. These tumors are called vestibular schwannomas (VSs), or acoustic neuromas.
- Trial name
- NCT01207687
- Testing
- bevacizumab, laboratory biomarker analysis, quality-of-life assessment
- Where
- 3 sites in United States
- Volunteers
- 14 people
- Sponsor
- National Cancer Institute (NCI)
Wound Heal, Peripheral Artery Disease
Safety and Efficacy of the Noxsano Wound Care Bandage
This study is a prospective, interventional, non-randomized study designed to assess the safety and efficacy of the Noxsano Bandage (study device) in healthy subjects and wound care subjects with a diabetic lower extremity…
- Conditions
- Wound Heal, Peripheral Artery Disease, Ulcer, Leg, Ulcer Foot
- Trial name
- NCT04123093
- Testing
- Noxsano Bandage (Healthy Volunteers), Noxsano Bandage (Wound Care)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- OhioHealth
Chronic Pain, Pediatric Disorder
PET/MRI in the Diagnosis of Pediatric Chronic Pain
[18F]FTC-146 is a sigma-1 receptor detector and is an experimental radiotracer. Several studies have implicated involvement of sigma-1 receptors in generation and perpetuation of chronic pain conditions, while others are…
- Conditions
- Chronic Pain, Pediatric Disorder, Neuropathic Pain, Nociceptive Pain
- Trial name
- NCT04435821
- Testing
- [18F]FTC-146
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stanford University
CIPN - Chemotherapy-Induced Peripheral Neuropathy
Effects of an Exercise Intervention on Taxane-induced Peripheral Neuropathy in Breast Cancer Survivors
The purpose of this study is to examine the effects of an exercise program on the management of TIPN in breast cancer survivors.
- Trial name
- NCT05641571
- Testing
- The home-based extremity exercise program
- Volunteers
- 88 people
- Sponsor
- Taichung Veterans General Hospital
Cervical Radiculopathy
Effects of Cervical Traction With and Without EMG Biofeedback in Patients With Cervical Radiculopathy
Cervical radiculopathy is a neurological condition which is caused by underlying musculoskeletal disorders including herniated disc and degenerative changes in cervical spine that results in narrowing or stenosis of…
- Trial name
- NCT05352464
- Testing
- cervical traction with EMG biofeedback, cervical traction and conventional physical therapy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Cervical Radiculopathy
Effects of Neural Glides Versus Proprioceptive Neuromuscular Facilitation in Cervical Radiculopathy
this project was a Quasi-Experimental Trial. conducted to compare the Effects of Neural Glides Versus Proprioceptive Neuromuscular Facilitation in Terms of Joint Position Sense and Pain in Cervical Radiculopathy .
- Trial name
- NCT04824170
- Testing
- Neural Glide, Rhythmic stabilization technique
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Nerve Compression Syndromes
Erythropoietin Spinal Cord Compression Randomized Trial
To determine whether erythropoietin, steroids and radiotherapy is safe and feasible to administer to patients with malignant spinal cord compression.
- Trial name
- NCT00220675
- Testing
- Erythropoietin infusion
- Where
- 3 sites in Canada
- Volunteers
- 7 people
- Sponsor
- Sunnybrook Health Sciences Centre
Pain, Pain Syndrome
Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis
Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates…
- Conditions
- Pain, Pain Syndrome, Pain, Chronic, Chronic Pain
- Trial name
- NCT06072001
- Testing
- Adezunap (AP707)
- Where
- Germany
- Volunteers
- 558 people
- Sponsor
- Apurano Pharmaceuticals GmbH
Carpal Tunnel Syndrome (CTS) Post-burn
Hand Function Outcome After the Application of Transfer Energy Capacitive and Resistive on Post-burn Patients Presented With Carpal Tunnel Syndrome
Carpal Tunnel Syndrome (CTS) is a common entrapment neuropathy that can develop as a secondary complication following deep burns involving the hand or wrist.
- Trial name
- NCT07660328
- Testing
- Transfer Energy Capacitive and Resistive (TECAR) [ SMART TECAR }, Standard Hand Rehabilitation [ US }
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Painful Diabetic Neuropathy
A Phase 2, Multicenter, Randomized, Double-blind, Placebo Controlled Study for the Pain of Diabetic Peripheral Neuropathy
Primary Objective: To evaluate the efficacy of SKL11197 for the treatment of diabetic peripheral neuropathy pain (DPN). Secondary Objective: To evaluate the safety and tolerability of SKL11197 in subjects with painful diabetic…
- Trial name
- NCT01521598
- Testing
- SKL11197
- Where
- 13 sites in United States
- Volunteers
- 128 people
- Sponsor
- SK Life Science, Inc.
Breast Cancer, Colorectal Cancer
Family Quality of Life Among Families With a Member Who is a Cancer Patient
RATIONALE: Developing a questionnaire that can be used to assess the quality of life among people who have a family member with cancer may help the study of cancer in the future.
- Conditions
- Breast Cancer, Colorectal Cancer, Head and Neck Cancer, Lung Cancer
- Trial name
- NCT00544336
- Testing
- questionnaire administration, survey administration, quality-of-life assessment
- Where
- 3 sites in United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Vanderbilt-Ingram Cancer Center
Thoracotomy, Thoracoscopy
Physiopathologic Study of Induced by Thoracotomy / Thoracoscopy Neuropathy Mechanism
Pulmonary surgery, performed routinely by thoracotomy or thoracoscopy, can cause significant and frequent chronic postoperative pain, most often neuropathic.
- Trial name
- NITT (NCT05307471)
- Testing
- Thoracotomy/scopy
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Clermont-Ferrand
Carpal Tunnel Syndrome
Investigating the Effect of Carpal Tunnel Syndrome on Activity and Participation
The aim of our study was to examine the effect of different severities of Carpal Tunnel Syndrome on activity and participation within the framework of the International Classification of Functioning, Disability and Health (ICF).
- Trial name
- NCT06635109
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Kutahya Health Sciences University
Neuropathic Pain, Complex Regional Pain Syndromes (CRPS)
Sub-threshold DRG Stimulation vs Sham in Established Responders
The goal of this clinical trial is to learn if sub-threshold dorsal root ganglion (DRG) stimulation provides pain relief beyond placebo in adults with chronic neuropathic pain who already have an implanted DRG stimulator.
- Conditions
- Neuropathic Pain, Complex Regional Pain Syndromes (CRPS), Causalgia, Chronic Pain
- Trial name
- DRG-SHAM (NCT07170722)
- Testing
- Subtreshhold DRG-S
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Umeå University
Lumbar Radiculopathy
Lumber Spine Mobilization and Spinal Traction on Lumber Radiculopathy.
Lumber radiculopathy, also known as sciatica, is a condition that causes pain in the lower back and legs due to irritation or compression of the spinal nerves. group between 20 and 50 years old.
- Trial name
- NCT06339931
- Testing
- SMWLM combined Spinal traction with belt, SMWLM combined spinal traction without belt
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Chemotherapy-induced Peripheral Neuropathy (CIPN), Gynecologic Cancers
Glove Compression for Chemotherapy-Induced Neuropathy
This study investigates whether wearing tight-fitting surgical gloves on the non-dominant hand could help prevent chemotherapy-induced peripheral neuropathy (CIPN) in women with gynecologic cancers treated with paclitaxel.
- Conditions
- Chemotherapy-induced Peripheral Neuropathy (CIPN), Gynecologic Cancers, Ovarian Cancer (OvCa), Endometrial Cancer
- Trial name
- NEURO-GLOVE (NCT07105553)
- Testing
- Surgical Glove Compression
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Etlik City Hospital
Diabetic Peripheral Neuropathy
Comparative Effects of Balance and Resisted Training in Diabetic Peripheral Neuropathy.
The aim of this study is to determine comparative effects of balance and resisted training on pain and balance in patients with daibetic peripheral neuropathy.
- Trial name
- NCT06303453
- Testing
- Balance exercises, Resisted exercises
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Riphah International University
Overactive Bladder
Association Between Metabolic Syndrome and Serum Nerve Growth Factor Levels in Women With Overactive Bladder
Nerve growth factor (NGF-R) receptors are between the detrusor muscle fibers and can cause afferent signals. Metabolic syndrome and obesity have been advocated to be risk factors for the development of overactive bladder.
- Trial name
- NGF (NCT02335853)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Herpes Zoster, Neuralgia
Controlled Study of NGX-4010 for the Treatment of Postherpetic Neuralgia
The purpose of the study is to assess the efficacy, safety and tolerability of NGX 4010 applied for 60 minutes for the treatment of PHN.
- Conditions
- Herpes Zoster, Neuralgia, Pain, Peripheral Nervous System Diseases
- Trial name
- NCT00068081
- Testing
- Capsaicin Dermal Patch
- Where
- 19 sites in United States
- Volunteers
- 150 people
- Sponsor
- NeurogesX
Visual Analogue Pain Scale, Pain Measurement
Efficacy of Radiofrequency Nucleoplasty and Targeted Disc Decompression in Lumbar Radiculopathy
The aim of this study is to compare early and long term efficacy of lumbar radiofrequency nucleoplasty and targeted disc decompression in patients with lumbar radiculopathy who failed previous conventional therapy.
- Trial name
- RFNaTDD (NCT02025283)
- Testing
- Group Decompression or Group Nucleoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 73 people
- Sponsor
- Ankara University
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