Clinical trials: Peripheral Nerve Injuries
Amyloidosis, Carpal Tunnel Syndrome
Carpal Tunnel Syndrome and Amyloidosis
Carpal tunnel syndrome has been suggested to be an early sign of amyloidosi. The investigators will evaluate tissue samples obtained from patients undergoing carpal tunnel release surgery for amyloid.
- Trial name
- AMICAR (NCT04245098)
- Testing
- Carpal tunnel syndrome surgery
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Corporacion Parc Tauli
Carpal Tunnel Syndrome
Flexor Tenosynovectomy to Treat Recurrent Carpal Tunnel Syndrome
The purpose of this study is to collect data on the clinical and functional outcomes of surgical management for recurrent carpal tunnel syndrome (CTS) using flexor tenosynovectomy.
- Trial name
- NCT03757416
- Testing
- Data collection
- Volunteers
- 2 people
- Sponsor
- University of Tennessee
Trigeminal Neuropathy, Traumatic
Botulinum Toxin Injections for Oral Neuropathic Pain
Peripheral painful traumatic trigeminal neuropathy (PPTTN) are poorly relieved by existing treatments which in addition induce many adverse effects.
- Trial name
- TRIGTOX (NCT03555916)
- Testing
- BOTOX®, Allergan
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Delirium - Postoperative
Effects of PNB Timing on Postoperative Delirium for Hip Fracture
Hip fracture is a common cause of hospitalization in older adults and is associated with substantial pain and a high risk of delirium.
- Trial name
- NCT07856108
- Testing
- Peripheral Nerve Block for Hip Fracture
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Carpal Tunnel Syndrome, Exercise
Carpal Tunnel Syndrome in Pregnant Women
The purpose of our study is to evaluate the effectiveness of the home exercise program in patients who develop Carpal tunnel syndrome (CTS).
- Trial name
- NCT03718598
- Testing
- Tendon and Nerve Gliding Exercises
- Volunteers
- 33 people
- Sponsor
- Bezmialem Vakif University
Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS)
Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test
The goal of this clinical trial is to understand how people make decisions about imaging tests for common musculoskeletal problems (like arthritis, tendon problems, or nerve compression).
- Conditions
- Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS), Lateral Epicondylitis, Osteoarthritis
- Trial name
- NCT07158892
- Testing
- Diagnostic Advance Care Planning Discussion, Informational Statement Only
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Texas at Austin
Carpal Tunnel Syndrome, Charcot-Marie-Tooth Disease
Patient Reported Outcomes Measures (PROM) in Carpal Tunnel Therapies in Patients With Inherited Neuropathies
The purpose of this study is to learn about focal compressive median neuropathy at the wrist (Carpal Tunnel Syndrome) and outcomes of therapies (e.g.
- Conditions
- Carpal Tunnel Syndrome, Charcot-Marie-Tooth Disease, Inherited Peripheral Neuropathy
- Trial name
- NCT02788734
- Testing
- Web-based survey
- Where
- United States
- Volunteers
- 333 people
- Sponsor
- University of South Florida
Transthyretin Amyloidosis, Carpal Tunnel Syndrome
Transthyretin Cardiac Amyloidosis in Patients With Idiopathic Carpal Tunnel Syndrome Referred for Release Surgery
This study will determine the prevalence of transthyretin amyloidosis in pathology of the transverse carpal ligament and cardiac involvement using natriuretic peptides, electrocardiography and echocardiography in patients…
- Trial name
- PRATHYC (NCT04611204)
- Testing
- Descriptive cohort
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Toulouse
Cubital Tunnel Syndrome, Ulnar Nerve Compression
Randomized Trial of Supercharged End-to-Side Anterior Interosseous Nerve Transfer for Severe Cubital Tunnel Syndrome
Functional motor recovery distal to a peripheral nerve lesion is predicated upon time to reinnervation of the motor end plate and the number of regenerate axons that reach the target.
- Conditions
- Cubital Tunnel Syndrome, Ulnar Nerve Compression, Ulnar Nerve Palsy, Ulnar Nerve Entrapment
- Trial name
- NCT04647058
- Testing
- Cubital tunnel release, Supercharged end-to-side (SETS) nerve transfer
- Where
- 2 sites in United States
- Sponsor
- Brigham and Women's Hospital
Peripheral Nerve Injury
Cortical Effects of Peripheral Nerve Injury At Birth
Cortical activity during rest and with stimulation by functional magnetic resonance imaging will be investigated in patients with OBPI.
- Trial name
- NCT02865317
- Volunteers
- 15 people
- Sponsor
- Gazi University
Peripheral Nerve Injuries
Preliminary Evaluation of the Clinical Safety and Effectiveness of the Bionic Nerve Scaffold
The objective of the study is to preliminarily evaluate the clinical safety and effectiveness of the bionic nerve scaffold with longitudinally oriented microchannels.
- Trial name
- NCT03780855
- Testing
- nerve scaffold
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xijing Hospital
Peripheral Nerve Injuries
Expanded Access - Autologous Human Schwann Cells in Peripheral Nerve Repair
Emergency expanded access for a single patient was granted to receive autologous human Schwann cell (ahSC) augmentation of nerve autograft repair after severe peripheral nerve injury (PNI).
- Trial name
- NCT04465929
- Testing
- Autologous Human Schwann Cells
- Where
- United States
- Sponsor
- W. Dalton Dietrich
Humeral Fractures, Ulnar Nerve Compression
Simple Decompression Versus Anterior Transposition of the Ulnar Nerve
Both simple decompression and anterior transposition of the elbow nerve (ulnar nerve) for acute displaced fractures of the elbow (distal humerus) treated with plate fixation are currently used by surgeons.
- Trial name
- NCT01051869
- Testing
- Simple decompression, anterior subcutaneous transposition
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- Unity Health Toronto
Carpal Tunnel Syndrome (CTS)
Effects of Peloid Therapy in Patients With Carpal Tunnel Syndrome
Carpal tunnel syndrome is a common condition caused by pressure on a nerve at the wrist. It can lead to pain, numbness, weakness, and difficulty using the hand during daily activities.
- Trial name
- NCT07417722
- Testing
- Peloid Therapy, Wrist Splint, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Peripheral Nerve Injury
Needle Nerve Contact in Ultrasound Guided Femoral Block
Ultrasound-guided femoral nerve block is a common regional anesthesia technique. The optimal method of needle guidance (in-plane versus out-of-plane) with regards to the block efficacy and avoidance of needle-nerve contact has…
- Trial name
- NCT01554722
- Testing
- Needle placement
- Where
- 2 sites in United States, Spain
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Diabetic Neuropathy, Neuropathic Pain
Pain In Neuropathy Study
In the context of peripheral neuropathy, we will aim to elucidate correlates between sensory symptoms and: Sensory nerve dysfunction. Cutaneous small nerve fibre innervation density. Psychological co-morbidity.
- Conditions
- Diabetic Neuropathy, Neuropathic Pain, Chronic Pain, Carpal Tunnel Syndrome
- Trial name
- PINS (NCT02672059)
- Testing
- Observation
- Where
- United Kingdom
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- King's College London
Carpal Tunnel Syndrome
Correlation of Different Ultrasonographic Indices With Clinical Parameters in Carpal Tunnel Syndrome
The aim of this study is to investigate the relationship between different ultrasonographic indices used in patients with carpal tunnel syndrome and clinical parameters.
- Trial name
- NCT06115187
- Testing
- Nerve ultrasound, Nerve conduction studies
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Carpal Tunnel Syndrome
Investigation of the Efficacy of Virtual Reality Mediated Neurodynamic Exercises in Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common nerve entrapment syndrome. It occurs as a result of compression of the median nerve as it passes through a restricted osteofibrous canal in the wrist.
- Trial name
- NCT05563909
- Testing
- Exercise, Wrist Splint, Virtual Reality Mediated Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Istanbul University
Carpal Tunnel Syndrome
Fascial Manipulation on the Treatment of Carpal Tunnel Syndrome
The trial aims to evaluate the effectiveness of Fascial Manipulation on pain reduction, functional recovery and nerve conduction of patients with Carpal Tunnel Syndrome (CTS).
- Trial name
- NCT02495298
- Testing
- Fascial Manipulation
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Marta Imamura
Carpal Tunnel Syndrome (CTS)
Effectiveness of PErcutaneous Ultrasound-guided Carpal Tunnel Release: a Non-inferiority Study With Surgery as Comparator
Carpal tunnel syndrome is a common condition caused by compression of the median nerve. Tingling in the first three or four fingers, usually at night or upon waking, is the most frequent symptom.
- Trial name
- EPEC (NCT07668310)
- Testing
- Carpal tunnel surgery, Questionnaires
- Where
- France
- Volunteers
- 7 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche