Clinical trials: Peripheral Nerve Injuries, open to volunteers
Carpal Tunnel Syndrome (CTS)
Reliability and Validity of Hand Function Tests in Carpal Tunnel Syndrome
Carpal tunnel syndrome is a condition that causes numbness, tingling, and weakness in the hand due to pressure on the median nerve in the wrist.
- Trial name
- NCT07706296
- Testing
- Standardized Hand Function and Dexterity Testing
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Izmir Bakircay University
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Carpal Tunnel Syndrome (CTS)
Hyaluronic Acid Injection in Idiopathic Carpal Tunnel Syndrome; is it Effective as Local Corticosteroids
This study compares the effectiveness of two types of local injections-Hyaluronic Acid (HA) and corticosteroids-for treating mild to moderate idiopathic Carpal Tunnel Syndrome (CTS).
- Trial name
- NCT07474714
- Testing
- Low Molecular Weight Hyaluronic Acid, corticosteroid
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University Hospital
Carpal Tunnel Syndrome (CTS), Carpal Tunnel Surgery
Evaluation by Clinical and Hand Ultrasound in Carpal Tunnel Syndrome
Carpal Tunnel Syndrome (CTS) is a common condition where pressure on the median nerve in the wrist causes pain, numbness, and weakness in the hand.
- Trial name
- ECHO-CTS (NCT07134361)
- Testing
- Open Carpal Tunnel Release
- Where
- Brazil
- Volunteers
- 106 people
- Sponsor
- University of Sao Paulo General Hospital
Carpal Tunnel Syndrome
Assessment of Carpal Tunnel Syndrome by Shearwave Elastography
This study is being done to test a new ultrasound method to detect possible stiffness problems within wrist(s). The purpose of this research is to the test the effectiveness of a new ultrasound method to check the nerve and…
- Trial name
- NCT04804293
- Testing
- FDA approved ultrasound system with shear wave elastography capability
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Peripheral Nerve Injuries
Continuous Observational Monitoring Program for Allay™ Hydrogel Cap Safety and Success Study
is is a multi-center, open-label, observational registry study (both prospective and retrospective) designed to evaluate the safety and performance of the allay™ Hydrogel Cap.
- Trial name
- COMPASS (NCT07246980)
- Testing
- Nerve Cap
- Where
- 5 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Tulavi Therapeutics,Inc.
Carpal Tunnel Syndrome (CTS)
Pilot Study, Aimed at Describing in Myography, the Collapse of the Muscular Response Visualized in the Scratch Collapse Test, in Carpal Tunnel Syndrome.
The Scratch Collapse Test (SCT) is a neurocutaneous reflex used to detect peripheral nerve compression in nerve tunnel syndromes.
- Trial name
- NCT07248124
- Testing
- electromyograph, Scratch Collapse Test
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Elsan
Carpal Tunnel Syndrome
Combined Manual Therapy and Percutaneous Neuromodulation for Moderate Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy and can cause pain, numbness, tingling, and functional impairment of the hand.
- Trial name
- MANUCTS (NCT07654621)
- Testing
- Combined Manual Therapy and Ultrasound-Guided Percutaneous Neuromodulation, Postsurgical Rehabilitation
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Universidad Europea de Valencia
Neurologic Disorders, Nervous System Diseases
Neurologic Stem Cell Treatment Study
This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3 of the nasal passages in order to determine if such a treatment will…
- Conditions
- Neurologic Disorders, Nervous System Diseases, Neurodegenerative Diseases, Neurological Disorders
- Trial name
- NEST (NCT02795052)
- Testing
- Intravenous and Intranasal BMSC
- Where
- 3 sites in United States, United Arab Emirates
- Volunteers
- 500 people
- Sponsor
- MD Stem Cells
Carpal Tunnel Syndrome
Validity and Reliability of Thai Version Clinical Questionnaire for Diagnosis of Carpal Tunnel Syndrome
The Kamath and Stothard clinical questionnaire for diagnosing carpal tunnel syndrome (CTS) is a valid score for diagnosis of CTS.
- Trial name
- NCT06239259
- Testing
- Questionare As described in Secondary Outcomes
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Siriraj Hospital
Carpal Tunnel Syndrome
Comparison of the Efficacy of Ultrasound-Guided Corticosteroid Injection and Paraffin Therapy in Carpal Tunnel Syndrome
The aim of this study is to compare the efficacy of paraffin therapy, a physical therapy modality, and ultrasound-guided corticosteroid injection in the treatment of carpal tunnel syndrome, the most common entrapment neuropathy.
- Trial name
- NCT06658886
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Beylikduzu State Hospital
Neuropathy;Peripheral, Limb Ischemia
Feasibility and Clinical Utility of Paired Non-Invasive Hemodynamic and Tissue Oximetry Monitoring to Detect Limb Ischemia in Lithotomy-Positioned Surgeries
The LIMB Study is a prospective, observational pilot study evaluating the feasibility of combined non-invasive hemodynamic and lower-limb tissue oximetry monitoring during prolonged minimally invasive pelvic surgeries performed…
- Trial name
- LIMB (NCT07387653)
- Testing
- Lower-Extremity Perfusion Monitoring
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Spinal Cord Injury Cervical, Spinal Cord Injuries (Complete and Incomplete)
Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia
The goal of this clinical trial is to learn more about how stimulating the nerves involved in sensation (either in the limbs or in the brain) can be used to restore sensation in participants who have a spinal cord injury.
- Trial name
- NCT07225582
- Testing
- Brain Computer Interface (BCI) - Functional Electrical Stimulation (FES) system
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Case Western Reserve University
Carpal Tunnel Syndrome
Exparel and Education to Avoid Opioids After Carpal Tunnel Release
This trial seeks to use the long acting local anesthetic Exparel, in conjunction with opioid education, to attempt to avoid any post-operative opioid use following carpal tunnel surgery.
- Trial name
- NCT03867539
- Testing
- Differing pain management strategy
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- Kettering Health Network
Scapholunate Advanced Collapse (SLAC), Scapholunate Crystalline Advanced Collapse (SCAC)
The KinematX Midcarpal Total Wrist Arthroplasty Registry
The goal of this observational study is to learn about functional and patient reported outcomes in patient undergoing total wrist replacement with the KinematX total wrist replacement study.
- Conditions
- Scapholunate Advanced Collapse (SLAC), Scapholunate Crystalline Advanced Collapse (SCAC), Scaphoid, Trapezium, and Trapezoid Advanced Collapse (STTAC), Carpal Tunnel Syndrome (CTS)
- Trial name
- NCT05719935
- Testing
- KinematX total wrist arthroplasty system
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- Extremity Medical
Carpal Tunnel Syndrome Treatment
Effectiveness of Corticosteroid and 5% Dextrose Versus USG-guided Ozone Injections in Patients With Carpal Tunnel Syndrome: Three Blind Randomized Studies
Effectiveness of corticosteroid and 5% dextrose versus USG-guided ozone injections in patients with carpal tunnel syndrome: Three blind randomized studies
- Trial name
- NCT07002892
- Testing
- Ozon treatment, Steroid treatment, Dextrose 5%
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Yunus Burak Bayır
Musculoskeletal Diseases, Median Nerve Disease
Comparison of Ultrasound-Guided Injection With Median Nerve Decompression Surgery in Carpal Tunnel Syndrome
The aim of this study is to compare ultrasound-guided perineural injection of the median nerve with classic minimal incision surgical technique for median nerve decompression in patients diagnosed with mild, moderate, and severe…
- Conditions
- Musculoskeletal Diseases, Median Nerve Disease, Carpal Tunnel Syndrome, Ultrasound-Guided Injection
- Trial name
- NCT06243848
- Testing
- Minimal Incision Surgery for median nerve decompression, Ultrasound-guided perineural injection with 5 cc 5% Dextrose
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Afyonkarahisar Health Sciences University
Tennis Elbow Syndrome, Golfer's Elbow
Effects of Peripheral Repetitive Peripheral Magnetic Stimulation on Individuals With Elbow or Wrist Chronic Pain
This pilot, randomized, sham-controlled, single-blind study will evaluate the effectiveness of repetitive peripheral magnetic stimulation (rPMS) in reducing pain in adults with tennis/golfer's elbow or carpal tunnel syndrome.
- Conditions
- Tennis Elbow Syndrome, Golfer's Elbow, Carpal Tunnel Syndrome (CTS)
- Trial name
- rPMS (NCT07544914)
- Testing
- Two days Active rPMS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
PTSD, Post Traumatic Stress Disorder PTSD
Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)
The goal of this clinical trial is to evaluate the safety and effectiveness of the gammaCore non-invasive vagus nerve stimulation (nVNS) device as an additional treatment for symptoms of post-traumatic stress disorder (PTSD) in…
- Conditions
- PTSD, Post Traumatic Stress Disorder PTSD, PTSD - Post Traumatic Stress Disorder, Post Traumatic Stress Disorder
- Trial name
- NCT07523685
- Testing
- non-invasive vagus nerve stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Acacia Clinics
Peripheral Nerve Injuries, Traumatic Peripheral Nerve Injury
High-Intensity Peripheral Magnetic Stimulation in Traumatic Peripheral Nerve Injury
Traumatic peripheral nerve injury is a common cause of chronic neuropathic pain, muscle weakness, and functional limitation, particularly in young and active individuals.
- Conditions
- Peripheral Nerve Injuries, Traumatic Peripheral Nerve Injury, Neuropathic Pain, Peripheral Nerve Injuries, Traumatic
- Trial name
- NCT07705490
- Testing
- High-Intensity Peripheral Magnetic Stimulation, Therapeutic Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital