Clinical trials: Peripheral Neuropathic Pain
Peripheral Neuropathy, Pain, Neuropathic
Distal Peripheral Neuropathy in Type 2 Diabetes
Distal sensory peripheral neuropathy (DSP) is a chronic, debilitating painful condition affecting quality of life in persons living with Type 2 diabetes.
- Conditions
- Peripheral Neuropathy, Pain, Neuropathic, Diabetes
- Trial name
- DSP/DM (NCT05104047)
- Testing
- Moxibustion - Traditional (Active), Moxibustion - Smokeless - (Active)
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- New York University
Chronic Pain, Chronic Lower Back Pain
Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain
Effective control of chronic pain is a top priority in the United States, as approximately 10% of adults have severe chronic pain most of which is chronic lower back pain (CLBP).
- Conditions
- Chronic Pain, Chronic Lower Back Pain, Back Pain, Opioid Use
- Trial name
- NCT04156802
- Testing
- Real TBS to the mPFC, Real TBS to the MC
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Wake Forest University Health Sciences
Diabetic Peripheral Neuropathic Pain
Efficacy and Safety of NYX-2925 in Subjects With Neuropathic Pain Associated With Diabetic Peripheral Neuropathy (DPN)
To evaluate the efficacy of NYX-2925 versus placebo in treating the neuropathic pain associated with diabetic peripheral neuropathy.
- Trial name
- NCT04146896
- Testing
- NYX-2925 50 mg
- Where
- 35 sites in United States
- Volunteers
- 228 people
- Sponsor
- Aptinyx
Peripheral Neuropathy, Neuropathic Pain
Study of Exablate Model 4000 Type 1.0/1.1 Following the Treatment of Neuropathic Pain
The Exablate 4000 obtained CE Mark for the treatment of Neuropathic Pain in December 2012. The purpose of this post market study is to obtain real world data on the safety and performance of the Exablate treatment for neuropathic…
- Trial name
- NCT05802511
- Testing
- Exablate treatment
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Peripheral Neuropathic Pain
ACD440 Gel in Peripheral Neuropathic Pain
This is a double-blind, randomized, placebo-controlled crossover outpatient study in patients with peripheral neuropathic pain with allodynia or hyperalgesia to cold, heat, brush and/ or pinprick stimulation.
- Trial name
- NCT05416931
- Testing
- ACD440 Gel 14mg/g
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- AlzeCure Pharma
Diabetic Peripheral Neuropathic Pain
Diabetic Neuropathic Pain Relief, 6 Weeks Dosage Sublingual Water-soluble CBD/PEA
The purpose of the study is to evaluate whether the DIA/NPR-6 is a better pain reliever in patients with diabetic neuropathic pain of the feet compared to placebo.
- Trial name
- NCT05766969
- Testing
- CBD/PEA
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Pure Green Pharmaceuticals Inc.
Diabetic Peripheral Neuropathic Pain
Slider Versus Tensioner Neural Mobilization in Diabetic Peripheral Neuropathy
Neurodynamics, i.e., the mobilization of the peripheral nervous system, is a physical approach to the treatment of pain; the method relies on influencing pain physiology via mechanical treatment of neural tissues and the…
- Trial name
- NCT05349357
- Testing
- Sliding Neural mobilization, Tensioner Neural mobilization, Stretching exercises
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Chronic Neuropathic Pain, Postoperative, Chronic Pain, Postoperative
Neuropathic Pain After Lung Surgery
To understand pain pathophysiology in terms of risk factors and protective mechanisms ranging from molecular pathways to societal impacts.
- Conditions
- Chronic Neuropathic Pain, Postoperative, Chronic Pain, Postoperative, Chronic Chemotherapy-induced Neuropathic Pain, Chronic Chemotherapy-induced Pain
- Trial name
- NCT02960971
- Testing
- Thoracic surgery for lung cancer
- Where
- 2 sites in Denmark
- Volunteers
- 78 people
- Sponsor
- Danish Pain Research Center
Neuropathic Pain, Neuropathy;Peripheral
The Effect of Lacosamide in Peripheral Neuropathic Pain
The main purpose of this study is to compare the change in pain intensity during treatment with a sodium-channel blocker (lacosamide) in patients with peripheral neuropathic pain with and without the irritable nociceptor…
- Conditions
- Neuropathic Pain, Neuropathy;Peripheral, Neuropathy, Painful, Neuropathy, Diabetic
- Trial name
- NCT03777956
- Testing
- Lacosamide
- Where
- Denmark
- Volunteers
- 63 people
- Sponsor
- Danish Pain Research Center
Peripheral Neuropathic Pain
Evaluation of the Efficacy and Tolerance of Low Doses of Ethosuximide in the Treatment of Peripheral Neuropathic Pain
Evaluation of the efficacy and tolerance of low doses of ethosuximide in the treatment of peripheral neuropathic pain
- Trial name
- E-PENEPA (NCT04431778)
- Testing
- Ethosuximide
- Where
- 11 sites in France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Clermont-Ferrand
Neuropathic Pain Associated With Diabetic Peripheral Neuropathy
A 2-part Trial to Learn More About How BAY1817080 Works, How Safe it is, and What the Right Dose is for Participants With Diabetic Neuropathic Pain
People suffering from diabetes often have high blood sugar levels. Over time this can affect many organs including the nerves in hands and feet and can cause a nerve pain called diabetic neuropathic pain (DNP).
- Trial name
- NCT04641273
- Testing
- BAY1817080, Pregabalin
- Where
- 42 sites in Czechia, Denmark and 8 more
- Volunteers
- 154 people
- Sponsor
- Bayer
Diabetic Peripheral Neuropathic Pain
A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled 14-week Study of DS-5565 in Chinese Patients With Diabetic Peripheral Neuropathic Pain
Investigate the efficacy and safety of mirogabalin in Chinese participants with diabetic peripheral neuropathic pain in comparison to placebo.
- Trial name
- NCT04094662
- Testing
- Mirogabalin
- Where
- 40 sites in China
- Volunteers
- 393 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Diabetic Peripheral Neuropathic Pain
Efficacy of Pregabalin Vs Duloxetine in Diabetic Peripheral Neuropathic Pain at Variable Dose
Background Diabetic neuropathy is a widespread, debilitating condition and its management needs a significant cost. Around, 50% of diabetes mellitus (DM) patients suffer from Diabetic Peripheral Neuropathic Pain (DPNP).
- Trial name
- NCT05292066
- Testing
- Duloxetine Tablets,, Pregabalin Tablets
- Volunteers
- 126 people
- Sponsor
- Aga Khan University
Percutaneous Electrical Nerve Stimulation, Peripheral Neuropathy
Percutaneous Electrical Nerve Stimulation Compared to Passive Assisted Neurodynamics in Brachial Plexus Neuropathy
Brachial plexus neuropathies, specifically of the median, radial, ulnar, suprascapular, axillary and dorsal scapular nerves, can arise when a peripheral nerve trunk or nerve root is subjected to injury, compression, inflammation…
- Conditions
- Percutaneous Electrical Nerve Stimulation, Peripheral Neuropathy, Neuropathic Pain
- Trial name
- NCT05432973
- Testing
- Percutaneous Electrical Nerve Stimulation, Neurodynamic and manual therapy
- Where
- Spain
- Volunteers
- 11 people
- Sponsor
- Universidad Rey Juan Carlos
Peripheral Neuropathic Pain
Post-marketing Surveillance (PMS) to Observe the Safety and Effectiveness of Lyrica CR Extended Release Tablets
This is an open-label, non-comparative, non-interventional, prospective, and multi-center PMS study to observe safety and effectiveness of Lyrica CR (82.5mg, 165mg, 330mg) in Korean subjects under the actual condition of use.
- Trial name
- NCT04171453
- Testing
- Lyrica CR (Pregabalin)
- Where
- 3 sites in South Korea
- Volunteers
- 600 people
- Sponsor
- Viatris Korea
Diabetic Peripheral Neuropathy, Diabetic Peripheral Neuropathic Pain
Exercise Induced Hypoalgesia Diabetes
The purpose of this research study is to learn whether different forms of exercise can reduce pain experienced by individuals with painful diabetic peripheral neuropathy.
- Trial name
- EIHDM (NCT05296642)
- Testing
- Moderate Cycling, Personalized Tourniquet System
- Where
- United States
- Sponsor
- University of Miami
Chemotherapy-induced Peripheral Neuropathy, Yoga
Yoga for Painful Chemotherapy-Induced Peripheral Neuropathy: A Pilot, Randomized-Controlled Study
This research study will examine the feasibility of conducting an eight-week yoga intervention for individuals with chronic painful chemotherapy-induced peripheral neuropathy.
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Yoga, Chronic Pain, Neuropathic Pain
- Trial name
- NCT03824860
- Testing
- Yoga
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Dana-Farber Cancer Institute
Neuropathic Pain, Neuropathy;Peripheral
Posterior-superior Insula Deep Brain Stimulation in Refractory Peripheral Neuropathic Pain Patients
This study evaluates the long term pain relief after deep brain stimulation on posterior-superior insula (PSI) in patients with refractory peripheral neuropathic pain who responded to real but not to sham non-invasive stimulation…
- Trial name
- PSI-DBS (NCT04279548)
- Testing
- Deep Brain Stimulation
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Sao Paulo
Chronic Neuropathic Pain, Postoperative, Chronic Pain, Postoperative
Neuropathic Pain After Breast Surgery
To understand pain pathophysiology in terms of risk factors and protective mechanisms ranging from molecular pathways to societal impacts.
- Conditions
- Chronic Neuropathic Pain, Postoperative, Chronic Pain, Postoperative, Chronic Chemotherapy-induced Neuropathic Pain, Chronic Chemotherapy-induced Pain
- Trial name
- NCT03124511
- Testing
- Surgery for breast cancer
- Where
- 2 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Danish Pain Research Center
Diabetic Peripheral Neuropathic Pain
The Effect of YJ001 on Diabetic Peripheral Neuropathic Pain.
In this study, a randomized, double-blind, placebo parallel-controlled design was used to evaluate the effectiveness and safety of YJ001 spray applied to local skin in patients with diabetic peripheral neuropathic pain, and to…
- Trial name
- NCT04953221
- Testing
- YJ001
- Where
- China
- Volunteers
- 225 people
- Sponsor
- Peking University Third Hospital