Clinical trials: Peripheral Neuropathic Pain
Neuralgia
Dose-Tolerability Titration Study to Evaluate The Efficacy And Safety Of Perampanel (E2007) In Patients With Post-Herpetic Neuralgia (PHN)
The purpose of the study is to determine the efficacy and safety of Perampanel (E2007) in patients with Post-Herpetic Neuralgia (PHN).
- Trial name
- NCT00592774
- Testing
- E2007 (perampanel)
- Where
- 47 sites in United States, Canada
- Volunteers
- 146 people
- Sponsor
- Eisai Inc.
Pain, Peripheral Neuropathy
Effects of Neurofeedback on Neural Function, Neuromodulation, and Chemotherapy-Induced Neuropathic Pain
The goal of this study is to learn if using a non-invasive therapy called "neurofeedback training" can help teach patients ways to modify their own brain waves to decrease the perception of pain and improve quality of life.
- Trial name
- NCT01278225
- Testing
- EEG biofeedback (BF) Group, Wait-List Control (WLC) Group, Follow UP Questionnaires
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- M.D. Anderson Cancer Center
Carpal Tunnel Syndrome, Splints
Comparison of Different Treatment Approaches in Carpal Tunnel Syndrome
The effectiveness of various external applications (strapping and splinting) on grip strength, pain intensity, symptom level, and functional status in carpal tunnel syndrome (CTS) has been compared in this study.
- Conditions
- Carpal Tunnel Syndrome, Splints, Rigid Taping, Kinesiotape
- Trial name
- NCT06238440
- Testing
- Splint and taping methods
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Muğla Sıtkı Koçman University
Peripheral Neuropathic Pain
Response Profiles to High-concentration Capsaicin Desensitization in Patients with Peripheral Neuropathic Pain with or Without Allodynia: a Regional Multicenter Prospective Cohort
Prospective multicenter cohort to determine patient profiles (associated factors, including allodynia) with a better response to pain desensitization by capsaicin delivered in the form of a high concentration patch (8%), in a…
- Trial name
- CAPSICAURA (NCT05817591)
- Testing
- Questionnaires
- Where
- 10 sites in France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Post-Herpetic Neuralgia
Efficacy and Safety of TRK-700 in Patient With Post-Herpetic Neuralgia
In Post-Herpetic Neuralgia(PHN) patients: To conduct an explorative investigation of the efficacy and safety of repeated oral doses of TRK-700 via a randomized double blind comparative study To measure the plasma concentration of…
- Trial name
- NCT02701374
- Testing
- TRK-700
- Where
- Japan
- Volunteers
- 184 people
- Sponsor
- Toray Industries, Inc
Cervicobrachial Neuralgia, Myofascial Pain Syndromes
Study to Evaluate the Efficacy of Botulinum Toxin Serotype A Injections for Cervicobrachial Myofascial Syndrome
Several studies have previously examined the use of botulinum toxin serotype A for myofascial pain of the neck and shoulders (cervicobrachial syndrome). These studies have suffered from: 1.
- Trial name
- NCT00241215
- Testing
- Botulinum toxin serotype A
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of California, Los Angeles
Cesarean Section, Pain, Postoperative
Regional Analgesia After Cesarean Section
All patients will be anaesthetized with spinal technique. Each patient will be treated with intravenous morphine - patient controlled analgesia (PCA).
- Conditions
- Cesarean Section, Pain, Postoperative, Pain, Neuropathic
- Trial name
- NCT03244540
- Testing
- TAP (transversus abdominis plane block), QLB (quadratus lumborum block), Stimuplex Ultra 360 needle
- Where
- 2 sites in Poland
- Volunteers
- 105 people
- Sponsor
- Medical University of Lublin
Neuropathic Pain
Burst Spinal Cord Stimulation for Neuropathic Pain
Recently a novel stimulation design was developed, called burst stimulation. In a non-placebo controlled pilot study burst stimulation seemed superior to tonic stimulation over a period extending more than 2 years, and even…
- Trial name
- NCT01486108
- Testing
- dorsal column stimulator
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- University Hospital, Antwerp
Diabetic Peripheral Neuropathy
Effects of Multisystem Exercise on Balance, Postural Stability, Mobility and Pain in Patients With DPN.
Upto the best knowledge of researcher, multisystem exercise program has been utilized in various populations, encompassing both healthy individuals and patients with diverse medical conditions.
- Trial name
- DPN (NCT06130917)
- Testing
- Multisystem Exercise, Conventional Treatment
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Pain, Trigeminal Neuralgia
Transcranial Magnetic Stimulation (TMS) Effects on Pain Perception
The purpose of this study is to investigate the effects of transcranial magnetic stimulation on pain perception.
- Conditions
- Pain, Trigeminal Neuralgia, Neuropathic Pain
- Trial name
- NCT00349050
- Testing
- laboratory pain assessment, transcranial magnetic stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Low Back Pain, Radiculopathy
The Effect of Comorbid Psychiatric Conditions on Results of Transforaminal Epidural Steroid Injection
Low back pain (LBP) and radiculopathic pain are a major socio-economic problem affecting all age groups. 70% of people consult a doctor at least once in their life due to LBP.
- Trial name
- NCT03821350
- Testing
- Information leaflet
- Volunteers
- 166 people
- Sponsor
- Hitit University
Carpal Tunnel Syndrome
Physical Therapy in the Treatment of Carpal Tunnel Syndrome
In the present investigation the pain reduction effects of a physical therapy technique will be compared to those produced by the absence of treatment, in subjects who suffer the signs and symptoms of carpal tunnel syndrome.
- Trial name
- NCT04329247
- Testing
- Median nerve neural mobilization
- Where
- Venezuela
- Volunteers
- 74 people
- Sponsor
- Universidad Europea de Madrid
Ehlers-Danlos Syndrome (EDS), Complex Regional Pain Syndrome (CRPS)
Two Point Discrimination
SPECIFIC AIMS Pain in both youth and adults is a complex, subjective and personal experience, and remains poorly understood. One particularly perplexing dimension of some forms of pain is the tendency of pain to spread outside of…
- Conditions
- Ehlers-Danlos Syndrome (EDS), Complex Regional Pain Syndrome (CRPS), Amplified Musculoskeletal Pain Syndrome (AMPS), Low Back Pain
- Trial name
- TPD (NCT03686748)
- Testing
- Two-point discrimination training, One-point discrimination training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Arthroscopic Knee Surgery, Lower Limb Fractures
Comparison of Gait Parameters Between Floor and Sponge Surfaces and Special Shoes
This study compares the gait pattern of individuals with weight bearing difficulties walking on the floor, a soft surface, or with special shoes (Kyboot).
- Conditions
- Arthroscopic Knee Surgery, Lower Limb Fractures, Back Pain and Asymmetric Gait, Complex Regional Pain Syndrome
- Trial name
- NCT02742376
- Testing
- Soft surface, Floor, Kyboot shoes
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Lumbosacral Radiculopathy
Procedural Framing and Epidural Steroid Injection Outcomes
Back pain is the leading cause of disability and military medical boards across the globe. Epidural steroid injections (ESI) are the most commonly performed pain procedure in the world.
- Trial name
- PEACE (NCT07498140)
- Testing
- Behavioral manipulation of ESI expectations, No behavioral manipulation of ESI expectations, No behavioral manipulation of pharmacotherapy expectations
- Where
- 4 sites in United States, Thailand and 1 more
- Volunteers
- 210 people
- Sponsor
- Northwestern University
Nerve Entrapments, Pelvic Pain
Integration of Intraoperative Neuromonitoring Into Decompression Surgery
To describe a novel technique by integrating the intraoperative neurophysiological monitoring (IONM) into laparoscopy to protect pelvic nerves by continuously monitoring when they are at risk during surgery.
- Trial name
- NCT06009640
- Testing
- Intraoperative neurophysiological monitoring with Nicolet Endeavor IOM Machine
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Herniated Disc, Low Back Pain
Efficacy of PLDD Versus ESI in the Treatment of Lumbar Radicular Pain
The most common cause of lumbar radicular pain is intervertebral disc herniation with or without pressure on the nerve root, which leads to inflammation and pain.
- Trial name
- NCT05601791
- Testing
- Epidural Steroid Injection, Percutaneous Laser Disc Decompression
- Where
- Croatia
- Volunteers
- 116 people
- Sponsor
- Osijek University Hospital
Diabetic Peripheral Neuropathy
Study of Low Level Laser Therapy to Treat Diabetic Peripheral Neuropathy Foot Pain
The purpose of this study is to determine whether low level laser therapy is effective in the reduction of foot pain associated with diabetic peripheral neuropathy.
- Trial name
- NCT02461225
- Testing
- Erchonia® FX-635™
- Where
- 2 sites in United States, Ireland
- Volunteers
- 30 people
- Sponsor
- Erchonia Corporation
Sciatica, Lumbar Disc Herniation
Electroacupuncture for Insomnia in Patients With Chronic Sciatica Due to Lumbar Disc Herniation: a Randomized Controlled Trial
The goal of this clinical trial is to learn if electroacupuncture can improve sleep in people with chronic sciatica caused by lumbar disc herniation. It will also assess the safety of this treatment.
- Conditions
- Sciatica, Lumbar Disc Herniation, Insomnia
- Trial name
- NCT07576348
- Testing
- Electroacupuncture
- Volunteers
- 114 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Chemotherapy-induced Peripheral Neuropathy
The Role of TRP Channels in CIPN
Part I: Evaluating the increase in dermal blood flow upon topical application of cinnamaldehyde and capsaicin on the fingers in healthy, male volunteers.
- Trial name
- NCT04415892
- Testing
- Cinnamaldehyde and capsaicin
- Where
- Belgium
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven