Clinical trials: Peripheral Neuropathy
Diabetic Neuropathy
The Effect of Random Vibrations on Perception and Balance
The purpose of this study is to investigate the effects of vibrating insoles on vibration perception threshold (VPT) and balance of people with diabetic neuropathy.
- Trial name
- NCT02989831
- Testing
- Vibrating insoles 'on'
- Volunteers
- 40 people
- Sponsor
- University Medical Center Groningen
Thoracic Outlet Syndrome
PECS II Block in Thoracic Outlet Decompression
Rationale: Postoperative pain management after transaxillary thoracic outlet decompression surgery (TATOD) is difficult. In a retrospective case-control trial, we found evidence that a PECS II block is able to reduce pain and…
- Trial name
- BLOCKTOS (NCT04471545)
- Testing
- Pectoral nerve block type II
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Carpal Tunnel Syndrome, Ulnar Nerve Compression
Objective Evaluation of the Scratch Collapse Test With Dynamometer, a Prospective Multicenter Trial.
Carpal tunnel syndrome and compression of the ulnar nerve at the elbow are common pathologies, which are treated surgically. Diagnosis is usually based on an electromyogram (EMG), as well as symptomatology, etiology of typical…
- Trial name
- NCT05989373
- Testing
- Scratch collapse test
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Clinique Saint Jean, France
Cubital Tunnel Syndrome
Immobilization Versus Immediate Motion After Anterior Submuscular Ulnar Nerve Transposition
The goal of this study is to test the hypothesis that immediate elbow motion is safe after anterior submuscular ulnar nerve transposition, and will not result in disruption of the repaired flexor pronator origin, under which the…
- Trial name
- NCT01781494
- Testing
- Immobilization followed by protected range of motion, Immediate range of motion
- Sponsor
- Mayo Clinic
Radiculopathy, Spondylolisthesis
Spondylolisthesis Treated With an iO-Flex® System Enabled Decompression
The purpose of this study is to evaluate the clinical performance of a decompression using the FDA cleared iO-Flex® System on-label in treating patients with spinal stenosis and stable grade I degenerative lumbar…
- Conditions
- Radiculopathy, Spondylolisthesis, Lumbar Spinal Stenosis
- Trial name
- STRiDE (NCT01338766)
- Testing
- Decompression using the iO-Flex® system
- Where
- 14 sites in United States
- Volunteers
- 100 people
- Sponsor
- Baxano Surgical, Inc.
Pain
Efficacy and Safety Study of Ataciguat Versus Placebo in Patients With Neuropathic Pain
The primary objective of this study is to assess the efficacy of ataciguat versus placebo in reducing pain intensity in patients with neuropathic pain.
- Trial name
- SERENEATI (NCT00799656)
- Testing
- ataciguat (HMR1766)
- Where
- 3 sites in Austria, Czechia and 1 more
- Volunteers
- 62 people
- Sponsor
- Sanofi
Pain, Pain, Acute
Assessing Opioid Care Practices Using CPV Patient Simulation Modules
This study will test the quality of opioid-related physician care decisions using a patient-simulation based measurement and feedback approach that combines multiple-choice care decisions with real-time, personalized scoring and…
- Conditions
- Pain, Pain, Acute, Pain, Chronic, Pain, Neuropathic
- Trial name
- NCT04080037
- Testing
- Quality IQ Patient Simulations
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Ischemic Stroke
The Impact of Electroacupuncture Combined With NGF on Clinical Effect and Functional Changes on Ischemic Stroke
Ischemic stroke is a common clinical disease, often accompanied by motor dysfunction and cognitive impairment. At present, clinical treatment for patients with ischemic stroke recovery is limited and ineffective.
- Trial name
- NCT05231694
- Testing
- Nerver growth factor (NGF) injection, EA intervention
- Where
- China
- Volunteers
- 288 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Ripertamab for the Treatment of Chronic Inflammatory Demyelinating Polyneuropathy
The goal of this clinical trial is to learn if ripertamab works to treat chronic inflammatory demyelinating polyneuropathy. It will also learn about the safety of ripertamab.
- Trial name
- RIPERT-CIDP (NCT06858722)
- Testing
- ripertamab
- Volunteers
- 175 people
- Sponsor
- Zhongming Qiu
Peripheral Neuropathy, Chemotherapy-induced Peripheral Neuropathy
Acupuncture for Symptoms of Nerve Damage
The purpose of this study is to compare the effects of real acupuncture with placebo acupuncture or usual care on symptoms of nerve damage from chemotherapy.
- Trial name
- NCT03183037
- Testing
- Acupuncture, Usual Care Group, questionnaires
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Deep Gluteal Syndrome, Piriformis Syndrome
Graston Technique in Deep Gluteal Syndrome
Deep gluteal syndrome describes the presence of pain in the buttock caused from non-discogenic and extrapelvic entrapment of the sciatic nerve.
- Trial name
- NCT04387877
- Testing
- Graston
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Koç University
Leukemia, Children With Cancer
Technology-Assisted Yoga and Exercise on Neuropathy and Pain in Children With Leukemia
The study was planned to examine the effects of technology-supported yoga and exercise on chemotherapy-induced peripheral neuropathy and pain in children aged 5-18 years with leukemia.
- Conditions
- Leukemia, Children With Cancer, Yoga Therapy, Excercise
- Trial name
- yogaCIPN (NCT06512012)
- Testing
- yoga and exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Dokuz Eylul University
Carpal Tunnel Syndrome
Very Low Frequency Magnetic Fields Versus the Supplement "Xinepa" in the Treatment of the Carpal Tunnel Syndrome
The purpose of the study is to determine the effectiveness of the treatment with very low frequency magnetic fields (ELF) on the reduction of pain and the relief of the associated signs such as sensitivity disorders that affect…
- Trial name
- NCT02891512
- Testing
- ELF, Xinepa®
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- University of Roma La Sapienza
Diabetic Peripheral Neuropathy
Effect of Circulating lncRNAs on Type 2 Diabetic Peripheral Neuropathy
This project intends to use high-throughput sequencing, molecular biology and bioinformatics technology to clarify the role of target lncrnas in the inflammatory response of DPN, to explore the correlation between target lncrnas…
- Trial name
- NCT04638556
- Testing
- lncRNA detection
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Jinshan Hospital Fudan University
Patient Compliance
A Randomized Controlled Trial to Assess the Effect of L-carnitine in Patients With Diabetic Peripheral Neuropathy to Relief Pain and Symptom Improvement
Diabetic Peripheral Neuropathy (DPN) is a common complication of diabetes mellitus. The prevalence rate is approaching towards a peak throughout the world including Bangladesh.
- Trial name
- NCT04145245
- Testing
- Levocarnitine
- Where
- Bangladesh
- Volunteers
- 104 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Central Nervous System Sensitization, Peripheral Nervous System Disorders
Effects of Soft Tissue Treatment vs Mechanisms Explanation to Treat Delayed Onset Muscles Soreness Among Sport Climbers
The aim of the present research is to define the effects of short manual treatment of soft tissues compared to mechanisms explaining in Delayed Onset Muscle Soreness (DOMS) among sport climbers and to address the mechanisms of…
- Conditions
- Central Nervous System Sensitization, Peripheral Nervous System Disorders, Muscle Soreness, Muscle Strength
- Trial name
- NCT04255212
- Testing
- Soft tissue treatment, Mechaninsms explanation, Control Group
- Where
- 2 sites in Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Diabetic Peripheral Neuropathy
The Effect of Related Blood Markers on Diabetic Peripheral Neuropathy
The goal of this observational study is to explore the relationship between related blood indicators and diabetic peripheral neuropathy(DPN).
- Trial name
- NCT06041412
- Where
- China
- Volunteers
- 1,400 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Low Back Pain, Neck Pain
Applying Artificial Intelligence in Developing Personalized and Sustainable Healthcare for Spinal Disorders
The primary objective is to use machine learning methods on large survey and health register data to identify participants with different treatment trajectories and health outcomes after surgical and/or conservative treatment for…
- Conditions
- Low Back Pain, Neck Pain, Disc Herniation, Disc Degeneration
- Trial name
- AID-Spine (NCT05745129)
- Where
- Norway
- Volunteers
- 165,000 people
- Sponsor
- Oslo Metropolitan University
Anti MAG Neuropathy
This Study Aims to Investigate the Efficacy of Photobiomodulation in the Treatment of Anti-MAG-induced Peripheral Neuropathy (LASER-MAG)
Patients treated in the hematology department of the Quimper/Cornouaille Hospital Center for IgM monoclonal gammopathy with anti-MAG and symptomatic peripheral neuropathy often reach a therapeutic impasse.
- Trial name
- LASER-MAG (NCT07661667)
- Testing
- photobiomodulation
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier de Cornouaille
Back Pain, Radiculopathy Lumbar
Threshold Response of Lumbar Selective Nerve Root Block in Predicting Good Outcome Following Lumbar Foraminotomy
SNRB, as measured by the change in pain and objective functional ability, can solicit crucial information regarding a patient's clinical picture and can predict a patient's outcome post-surgery.
- Conditions
- Back Pain, Radiculopathy Lumbar, Degenerative Lumbar Spinal Stenosis
- Trial name
- NCT03801356
- Testing
- Selective Nerve Root Block
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- The Cleveland Clinic