Clinical trials: Peripheral Neuropathy
Painful Diabetic Neuropathy
Electromagnetic Stimulation (FREMS) in Patients With Painful Diabetic Neuropathy
We postulate that frequency-modulated electromagnetic stimulation (FREMS) may decrease pain in patients with painful diabetic neuropathy.
- Trial name
- NCT00337324
- Testing
- Frequency-modulated electromagnetic neural stimulation
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- IRCCS San Raffaele
Painful Diabetic Neuropathy
Trazodone in Painful Diabetic Neuropathy
The aim of the study is to collect preliminary information on the effect of low doses of trazodone on pain intensity in patients with painful diabetic neuropathy and to evaluate the neuropathic pain symptoms, anxiety, sleep…
- Trial name
- NCT03202979
- Testing
- Trazodone 20 mg, Trazodone 10 mg
- Where
- 20 sites in Czechia, Hungary and 1 more
- Volunteers
- 142 people
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Diabetic Neuropathies
Effect of Neurodynamic Mobilization Techniques in Patients With Diabetic Neuropathy
Neurodynamic mobilization Techniques and Selected Physical program used as a treatment for diabetic neuropathy patients and assessed by nerve condition study and function outcome.
- Trial name
- NCT05628168
- Testing
- Neurodynamic Mobilization Techniques, Selected Physical Therapy Program
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- October 6 University
Laser Acupuncture, Flexor Tendon Repair
Efficacy of Laser Acupuncture on Carpal Tunnel Syndrome Following Hand Flexor Tendon Repair
The purpose of this study is to determine the efficacy of laser acupuncture in alleviating CTS symptoms following flexor tendon repair in the hand.
- Conditions
- Laser Acupuncture, Flexor Tendon Repair, Hand Surgery, Carpal Tunnel Syndrome (CTS)
- Trial name
- LASER (NCT07014774)
- Testing
- Laser acupuncture, Traditional Therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Pudendal Neuralgia
Impact of Adding TENS to Conventional Physical Therapy Exercise on Pain Relief Among Patients With Pudendal Neuralgia.
Fifty two male participants, 30-50 years old, suffering from chronic pudendal neuralgia were randomly assigned either into experimental group (26 patients) received TENS plus the traditional physical therapy program( including…
- Trial name
- TENS (NCT04455659)
- Testing
- Trans-cutaneous Electrical Nerve Stimulation, Conventional physical therapy exercise
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Peripheral Nervous System Diseases, Testicular Neoplasms
Establishing of Neuronal-like Cells From Patients With Cisplatin-Induced Peripheral Neuropathy
This study targets patients with cisplatin-induced peripheral neuropathy and will allow us to: a) study peripheral neuropathy in diverse human sensory neurons in ways that were not possible previously; b) gain insight on…
- Trial name
- NCT02492360
- Testing
- Blood sample collection, Report of peripheral neuropathy after cisplatin therapy
- Where
- United States
- Sponsor
- Costantine Albany
Painful Polyneuropathy
Levetiracetam for Painful Polyneuropathy
Polyneuropathy of different etiologies is often associated with pain. The standard treatment of this pain is anticonvulsants or antidepressants, but none of these treatment are effective or tolerable for all patients.
- Trial name
- NCT00286260
- Testing
- levetiracetam
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Odense University Hospital
Ultrasound, Education
Tele-Ultrasound: VIrtual Hands-on Education for Novice Users
This study is intended to perform a comparative analysis of novice ultrasound users when taught in person versus virtually. This study aims to show that students will not demonstrate a statistical difference in scores learning in…
- Conditions
- Ultrasound, Education, Virtual
- Trial name
- NCT05013476
- Testing
- Butterfly handheld ultrasound machine
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
CRPS (Complex Regional Pain Syndromes)
Forward Looking InfraRed Imaging and Severity Score in Complex Regional Pain Syndrome
The goal of this interventional study is to explore the use of InfraRed (FLIR) imaging in determining pain intensity and severity in newly diagnosed complex regional pain syndrome patients.
- Trial name
- FLIR (NCT05852210)
- Testing
- Infrared Imaging
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hospital for Special Surgery, New York
Small-Fiber Neuropathy
Evaluation of Pregabalin in Idiopathic Small Fiber Neuropathy
Idiopathic Small Fiber Neuropathy (called SFN for short), is a condition where nerves that sense pain have become damaged, and often painful.
- Trial name
- NCT00787462
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Neuropathic Pain
Adrenocorticotropic Axis and Neuropathic Pain
Chronic pain is often associated with a chronic stress and HHSG axis plays a pivotal role in maintaining homeostasis. The literature reports that pain in patients treated with opioids, significant changes are taking place in this…
- Trial name
- HORMONES (NCT01543425)
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Sciatica, Electroacupuncture
Effectiveness of Electro-acupuncture and Manual Therapy on Pain and Fucntion in Patients With Sciatica
The aims of the study are: To study the pain efficacy of an electroacupuncture and manual therapy protocol versus the use of manual therapy in patients with sciatica.
- Conditions
- Sciatica, Electroacupuncture, Manual Therapy
- Trial name
- NCT04764890
- Testing
- Electroacupuncture, Manual therapy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- CEU San Pablo University
Neurofibromatosis Type 1, Recurrent Childhood Pilocytic Astrocytoma
Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma
This randomized phase II trial studies how well low-dose lenalidomide works compared with high-dose lenalidomide in treating younger patients with juvenile pilocytic astrocytomas or optic nerve pathway gliomas that have come back…
- Conditions
- Neurofibromatosis Type 1, Recurrent Childhood Pilocytic Astrocytoma, Recurrent Childhood Visual Pathway Glioma
- Trial name
- NCT01553149
- Testing
- Lenalidomide, Pharmacological Study
- Where
- 126 sites in United States, Australia and 2 more
- Volunteers
- 75 people
- Sponsor
- National Cancer Institute (NCI)
HFpEF - Heart Failure With Preserved Ejection Fraction, HFmrEF
US Benchmarking Clinical Study
The goal of this observational study is to measure shear wave velocity (SWV) in patients with non-reduced left ventricular ejection fraction (LVEF) heart failure and left ventricular hypertrophy, with or without transthyretin…
- Conditions
- HFpEF - Heart Failure With Preserved Ejection Fraction, HFmrEF, ATTR-CM (Transthyretin Amyloid Cardiomyopathy), Left Ventricular Hypertrophy
- Trial name
- EMS-CT-1 (NCT07215715)
- Where
- 3 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- eMyosound SAS
Sciatica Acute, Sciatica
COMPARISON OF EFFICACY OF DIFFERENT DRUG COMBINATIONS IN ACUTE SCIATICA
The goal of this clinical trial is to compare different combinations of diclofenac with diclofenac monotherapy in acute sciatica.
- Trial name
- EDCLAS (NCT05626140)
- Testing
- Lacosamide 50 MG Oral Tablet [Vimpat], Codeine Phosphate, Diclofenac Sodium
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Pakistan Institute of Medical Sciences
Pain, Neuropathic, Failed Back Surgery Syndrome
Coordinated Reset Spinal Cord Stimulation
The goal of this study is to evaluate whether a new spinal cord stimulation paradigm, called Coordinate Reset (CR) Stimulation, can provide equivalent or better pain relief with reduced energy requirements.
- Trial name
- NCT04997278
- Testing
- Coordinated Reset spinal cord stimulation
- Where
- United States
- Sponsor
- Stanford University
Carpal Tunnel Syndrome, Trigger Finger
Question Prompt List for Common Hand Conditions
Patients with common hand conditions will be randomized to one of two groups- one will receive a question prompt list, the other will receive a list of 3 questions
- Conditions
- Carpal Tunnel Syndrome, Trigger Finger, Trigger Thumb, Dupuytren Contracture
- Trial name
- NCT03868449
- Testing
- Question Prompt List, 3 questions
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Stanford University
Diabetic Neuropathy, Painful
Tolerability of Switching to Duloxetine for the Management of Diabetic Nerve Pain
This study is to compare the tolerability of different methods for switching from another medication to duloxetine for the management of diabetic nerve pain.
- Trial name
- NCT00266643
- Testing
- duloxetine hydrochloride
- Where
- 20 sites in United States, Puerto Rico
- Volunteers
- 205 people
- Sponsor
- Eli Lilly and Company
Piriformis Syndrome
Comparative Effect of Active Release Technique Versus Self-myofascial Release in Improving Piriformis Syndrome
The goal of this Randomized controlled trial is to examine comparative effect of active release technique versus self-myofascial release in improving piriformis syndrome.
- Trial name
- NCT05742633
- Testing
- Active release technique, Self-myofascial release
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Sehat Medical Complex
Amyloid Neuropathies, Transthyretin Amyloidosis
Expanding the Biomarkers in Familial Amyloid Neuropathy: MRI and Motor Unit Estimation by Electrophysiological Study
Familial amyloid neuropathies (FAP) are hereditary disease due to a mutation of the tranthyretin gene (TTR). These neuropathies are severe and life frightening.
- Trial name
- NCT03588468
- Testing
- Electrophysiological biomarkers, MRI biomarkers
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille