Clinical trials: Peripheral Neuropathy Pain
Neurofibromatosis Type 1
A Study to Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)
Background: Neurofibromatosis type 1 (NF1) is a genetic condition that causes tumors to grow along the nerves in the skin, brain, and other parts of the body.
- Trial name
- NCT06507748
- Testing
- AlgometRx Nociometer(R)
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- National Cancer Institute (NCI)
Neuropathic Pain
EPT 100: Geranium Oil for the Relief of Neuropathic Pain
The purpose of this study is to determine if Geranium oil will relieve a variety of neuropathic pain and some pain relief will last more than 48 hours.
- Trial name
- Geranium Oil (NCT01007747)
- Testing
- Geranium oil
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Pennington Biomedical Research Center
Lumbar Radiculopathy
Comparative Effects Between ELDOA and Spinal Mobilization With Limb Movement in Lumbar Radiculopathy
This study examines the comparative effects of ELDOA and Spinal Mobilization with Leg Movement (SMWLM) on lumbar radiculopathy
- Trial name
- NCT07328282
- Testing
- ELDOA, Spinal Mobilization with Limb Movement - SMWLM
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Foundation University Islamabad
Neuropathic Pain, Complex Regional Pain Syndrome Type 1
Effectiveness of Ketamine Administered by Mesotherapy in Complex Regional Pain Syndrome Type 1 (CRPS1)
Complex Regional Pain Syndrome type 1 (CRPS1) is a disabling pain syndrome. Its definitive treatment has not been established and the results of current treatments are often unsatisfactory.
- Trial name
- MESO-SDRC (NCT04650074)
- Testing
- LIDOCAINE 20 mg, LIDOCAINE 20 mg + KETAMINE 20 mg, LIDOCAINE 20 mg + KETAMINE 40 mg
- Where
- France
- Volunteers
- 31 people
- Sponsor
- Hospices Civils de Lyon
Carpal Tunnel Syndrome (CTS)
Pregabalin Phonophoresis for Carpal Tunnel Syndrome Pain
Carpal tunnel syndrome (CTS) is a common condition caused by pressure on the median nerve in the wrist, leading to pain, numbness, and weakness in the hand. Oral medications for nerve pain can have significant side effects.
- Trial name
- PREG-CTS-USG (NCT07613476)
- Testing
- Pregabalin Phonophoresis, Therapeutic Ultrasound
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Faisalabad
Carpal Tunnel Syndrome
Effectiveness of Desensitisation and Pain Neuroscience Education in Patients With Carpal Tunnel Syndrome With Nosiplastic Pain
The aim of our study was to determine the effectiveness of desensitisation and pain neuroscience education in a group of patients with mixed phenotype pain (neuropathic and nosiplastic).
- Trial name
- NCT06635213
- Testing
- Desensitisation, Pain neuroscience education
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kutahya Health Sciences University
Mitochondrial Diseases, Developmental Delay Disorder
Reference Values of Intraepidermal Nerve Fiber Density in Children and Small Fiber Neuropathy in Neurodevelopmental Disorders
Background: Small-Fiber-Neuropathy describes the degeneration of mildly or unmyelinated nerve fibers and causes neuropathic pain and autonomic dysfunction.
- Conditions
- Mitochondrial Diseases, Developmental Delay Disorder, Small Fiber Neuropathy, Cerebral Palsy
- Trial name
- SFN_children (NCT05645874)
- Testing
- Skin biopsy
- Where
- Germany
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Low Back Pain, Lumbar Disc Disease
Efficacy of Mechanical Traction and Spinal Decompression Treatments in Patients With Low Back Pain
Motorized traction and non-surgical spinal decompression treatments are relatively new treatments for which there is insufficient evidence in the literature.
- Conditions
- Low Back Pain, Lumbar Disc Disease, Lumbar Disc Herniation, Lumbar Radiculopathy
- Trial name
- NCT05617924
- Testing
- Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Afyonkarahisar Health Sciences University
Pain, Postoperative, Adult
Longitudinal Assessment of Pain-Related Patient-Reported Outcomes After Surgery
Little is known about pain-related outcomes experienced by patients in the first few weeks after surgery, once they are discharged from hospital.
- Conditions
- Pain, Postoperative, Adult, Pain Measurement, Functional Status
- Trial name
- NCT05315596
- Where
- 16 sites in Germany, Mexico
- Volunteers
- 1,000 people
- Sponsor
- Jena University Hospital
Peripheral Nerve Injuries, Traumatic Peripheral Nerve Injury
High-Intensity Peripheral Magnetic Stimulation in Traumatic Peripheral Nerve Injury
Traumatic peripheral nerve injury is a common cause of chronic neuropathic pain, muscle weakness, and functional limitation, particularly in young and active individuals.
- Conditions
- Peripheral Nerve Injuries, Traumatic Peripheral Nerve Injury, Neuropathic Pain, Peripheral Nerve Injuries, Traumatic
- Trial name
- NCT07705490
- Testing
- High-Intensity Peripheral Magnetic Stimulation, Therapeutic Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Pain, Neuropathic
Pregabalin add-on for Neuropathic Pain in Cervical Myelopathy
There is no information on the effect of pregabalin in patients with neuropathic pain in cervical myelopathy under routine clinical practice.
- Trial name
- NCT03618589
- Testing
- Pregabalin, Opioid
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Back Pain With Radiation, Radiculopathy
Lumbar Operatively Inserted PerQdisc Artificial Implant Following Nuclectomy 3
This study is a First in Human, prospective, multi-center clinical study intended to collect safety and performance information for the Spinal Stabilization Technologies PerQdisc® Nucleus Replacement System and procedure…
- Conditions
- Back Pain With Radiation, Radiculopathy, Back Pain, Disc Herniation
- Trial name
- LOPAIN3 (NCT05732818)
- Testing
- PerQdisc Nucleus Replacement System
- Where
- 2 sites in Paraguay, Uzbekistan
- Volunteers
- 50 people
- Sponsor
- Spinal Stabilization Technologies
Geriatric Pain
Frailty and Chronic Pain Profiles in Patients Aged ≥65 Years
The primary aim of this study is to investigate the relationship between frailty status and pain type, pain localization, and the Geriatric Nutritional Risk Index (GNRI) in individuals aged 65 years and older who present to an…
- Trial name
- F&P (NCT07373860)
- Where
- Turkey (Türkiye)
- Volunteers
- 393 people
- Sponsor
- Ankara City Hospital Bilkent
Cervico Brachialgia
Neural Mobilization in Cervico-Brachial Neuralgia
This study aimed to compare the effectiveness of neural mobilization (NM) combined with conventional rehabilitation versus conventional rehabilitation alone in patients with chronic common cervico-brachial neuralgia (CBN)…
- Trial name
- NM-CBN (NCT06913062)
- Testing
- conventional rehabilitation, neural mobilisation
- Where
- Tunisia
- Volunteers
- 32 people
- Sponsor
- Hopital Charles Nicolle
Herpes Zoster Pain, Neuralgia, Postherpetic
High-Voltage Long-Duration Pulsed Radiofrequency Combined With Liposomal Bupivacaine Subcutaneous Block for Herpes Zoster-Associated Neuralgia
Research Objectives Background and Significance: Zoster-associated neuralgia (ZAN) refers to neuropathic pain experienced by herpes zoster (HZ) patients before, during, and after rash resolution, characterized by paroxysmal…
- Trial name
- NCT06959147
- Testing
- High-Voltage Long-Duration Pulsed Radiofrequency plus Liposomal Bupivacaine group, High-Voltage Long-Duration Pulsed Radiofrequency
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Shirong Tan
Complex Regional Pain Syndrome
Double Blind Placebo Controlled Study of Outpatient Intravenous Ketamine for the Treatment of CRPS
Complex Regional Pain Syndrome is a debilitating and extremely difficult to treat condition. There is a large body of evidence demonstrating the therapeutic value of N-methyl-D-aspartate (NMDA)-receptor antagonists in CRPS.
- Trial name
- NCT00579085
- Testing
- Ketamine, IV NSS, Normal Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Drexel University College of Medicine
Lumbar Degenerative Disease, Lumbar Radiculopathy
Comparison of Clinical Effectiveness of Full Endoscopic Lumbar Discectomy (FELD) and Microdiscectomy (MD) in Patients With Lumbar Disc Herniation
The goal of this clinical trial is to compare the clinical effectiveness of Full Endoscopic Lumbar Discectomy (FELD) and Microdiscectomy (MD) in patients aged 18-85 with single-level lumbar disc herniation who have not undergone…
- Conditions
- Lumbar Degenerative Disease, Lumbar Radiculopathy, Sciatic Leg Pain, Sciatic Nerve Compression
- Trial name
- NCT06615518
- Testing
- FELD (Full-Endoscopic Lumbar Discectomy), comprising IELD and TELD as anatomical subgroups, Microdiscectomy
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- University of Opole
Partial Pneumonectomy Under Lateral or Posterolateral Thoracotomy.
Effects of Perioperative Systemic Ketamine on Development of Long-term Neuropathic Pain After Thoracotomy
Lung surgery under thoracotomy is known to induce long-term pain which can be considered as neuropathic in many patients concerned [1,2]. The suspected origin of neuropathy is a direct traumatism of intercostal nerve(s) [3].
- Trial name
- NCT00313378
- Testing
- Hypothetica
- Where
- France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Clermont-Ferrand
Neuralgia, Pain
Pilot Study of High-Dose Capsaicin Patches to Treat Postherpetic Neuralgia Pain
The purpose of this study is to gain initial information on the tolerability of high-dose capsaicin patches in patients with Painful Postherpetic Neuralgia.
- Conditions
- Neuralgia, Pain, Peripheral Nervous System Diseases, Herpes Zoster
- Trial name
- NCT00034710
- Testing
- Capsaicin Patch
- Where
- 8 sites in United States
- Volunteers
- 42 people
- Sponsor
- NeurogesX
Diabetic Neuropathic Pain
the Effectiveness of Intermittent Pneumatic Compression on Neuropathic Pain in Patients With Diabetic Polyneuropathy
In this study,the effectiveness of intermittent pneumatic compression therapy on neuropathic pain and quality of life in patients with neuropathic pain due to type 2 diabetes was investigated
- Trial name
- NCT06336486
- Testing
- intermittent pneumatic compression +pregabalin group, pregabalin group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Busra Gunes
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