Clinical trials: Peripheral Neuropathy Pain
Neuropathic Pain Associated With Diabetic Peripheral Neuropathy
A 2-part Trial to Learn More About How BAY1817080 Works, How Safe it is, and What the Right Dose is for Participants With Diabetic Neuropathic Pain
People suffering from diabetes often have high blood sugar levels. Over time this can affect many organs including the nerves in hands and feet and can cause a nerve pain called diabetic neuropathic pain (DNP).
- Trial name
- NCT04641273
- Testing
- BAY1817080, Pregabalin
- Where
- 42 sites in Czechia, Denmark and 8 more
- Volunteers
- 154 people
- Sponsor
- Bayer
Electroacupuncture, Acupuncture
Effect of Electroacupuncture on Sensitive Symptoms of Distal Diabetic Peripheral Neuropathy
This is a controlled clinical trial with the aim to study the effects of electroacupuncture on neuropathic pain reduction, quality of life and changes in sensory and motor nerve conduction velocity in patients with type 2…
- Conditions
- Electroacupuncture, Acupuncture, Diabetic Polyneuropathy, Diabetic Peripheral Neuropathy
- Trial name
- EA&DPN (NCT05521737)
- Testing
- Electroacupuncture
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- Instituto Mexicano del Seguro Social
Postherpetic Neuralgia ( PHN )
Effectiveness of Warm Acupuncture in Patients with Postherpetic Neuralgia
Postherpetic neuralgia (PHN) is the most common clinical complication of herpes zoster. PHN can persist for months to years, and in some cases, the pain may last for more than five years.
- Trial name
- NCT06893172
- Testing
- Warm acupuncture and Gabapentin, Gabapentin
- Volunteers
- 36 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Cervical Radiculopathy, Neck Pain
A Comparison Study Between Contrast Spread and Loss of Resistance Techniques
Early epidural space identification is critical to the efficacy and safety of cervical epidural steroid injections (CESI) [1]. Currently, the accepted method for epidural space recognition is the loss of resistance technique…
- Conditions
- Cervical Radiculopathy, Neck Pain, Disc Prolapse With Radiculopathy
- Trial name
- NCT05260294
- Testing
- Epidural space identification with cervical epidural steroid injection employing CST and LORT.
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Yakov Perper, MD
Small Fiber Neuropathy
A Study to Evaluate the Efficacy and Safety of VX-150 in Treating Subjects With Pain Caused by Small Fiber Neuropathy
This is a Phase 2, randomized, double-blind, placebo-controlled, parallel-group, multicenter study evaluating the efficacy of VX-150 for the treatment of pain caused by small fiber neuropathy.
- Trial name
- NCT03304522
- Testing
- VX-150
- Where
- 34 sites in United States, Germany and 2 more
- Volunteers
- 89 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Neuropathic Pain, Complex Regional Pain Syndrome
IV Lidocaine Infusion for Neuropathic Pain
The investigators will conduct a retrospective cohort study of patients who have undergone i.v. lidocaine infusions in the previous 2 years for suspected neuropathic pain of heterogeneous origin.
- Conditions
- Neuropathic Pain, Complex Regional Pain Syndrome, Chronic Pain
- Trial name
- NCT05731739
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Neurofibromatosis Type 1, Plexiform Neurofibromas
Acceptance and Commitment Training for Adolescents and Young Adults With Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain
Background: People with neurofibromatosis type I (NF1) and plexiform neurofibroma (PN) tumors often have chronic pain that his hard to control.
- Trial name
- NCT02471339
- Testing
- Acceptance and Commitment Therapy (ACT)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- National Cancer Institute (NCI)
Carpal Tunnel Syndrome
Dexmedetomidine Versus Triamcinolone Treatment in Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is a common mononeuropathy due to entrapment of the median nerve in the carpal tunnel. a lot of modalities are available for treatment of mild to moderate CTS.
- Trial name
- NCT05624866
- Testing
- Dexmedetomidine, Triamcinolone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Sciatica, Lumbar Disc Herniation
Trial of Pulsed Radiofrequency for Sciatica and Disc Herniation
Transforaminal epidural injection of treatments, commonly steroids (TFESI), is offered to people with sciatica and might improve symptoms, reduce disability and speed up return to normal activities (NICE guidelines)…
- Trial name
- PRATS (NCT04209322)
- Testing
- pulsed Radiofrequency, Transforaminal Epidural Steroid Injection
- Where
- 2 sites in Italy
- Volunteers
- 250 people
- Sponsor
- University of Roma La Sapienza
Hernia, Inguinal, Inguinal Hernia, Direct
Study of Laparoscopic Inguinal Hernia Repair
Although mesh fixation has been associated to an increased incidence of nerve injury and involves increased operative costs, many surgeons feel that fixation is necessary to reduce the risk of hernia recurrence.
- Conditions
- Hernia, Inguinal, Inguinal Hernia, Direct, Inguinal Hernia, Indirect, Hernia, Femoral
- Trial name
- NCT02920307
- Testing
- TEP without fixation, TEP with fixation, TAPP without fixation
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Medical Park Gaziantep Hospital
Spinal Cord Injury, Neuropathic Pain
Neuropathic Pain Study With Botulinum Toxin A in Spinal Cord Injury Patients
The purpose of this study is to determine whether botulinum toxin A is effective in the treatment of neuropathic pain in spinal cord injury patients.
- Trial name
- NCT01579500
- Testing
- Botulinum toxin type A, normal saline
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Catholic University of Korea Saint Paul's Hospital
Diabetic Polyneuropathy
HTEMS Treatment of Diabetic Polyneuropathy
So far, there are no sufficient pharmacologic therapies for the treatment of diabetic neuropathy. Therefore, we evaluated application of high-tone external muscle stimulation (HTEMS) compared to placebo treatment in patients with…
- Trial name
- HTEMS-RCT (NCT04593992)
- Testing
- HTEMS
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- West German Center of Diabetes and Health
Postherpetic Neuralgia
An Open-Label Follow-on Trial to Assess the Long-Term Safety and Efficacy of Oral SPM 927 in Subjects With Postherpetic Neuralgia (PHN)
This trial was the follow-on trial to a preceeding double-blind, placebo controlled trial which included patients with at least moderate pain due to postherpetic neuralgia.
- Trial name
- NCT00238511
- Testing
- SPM 927
- Where
- Germany
- Sponsor
- UCB Pharma
Radiculopathy, Sciatica
Clinical Trial to Evaluate the Safety and Analgesic Efficacy of VVZ-149 in Lumbar Radiculopathy (Sciatica)
Double-blind, crossover, randomized, 3x3 Latin square, placebo-controlled study of single intravenous dose administration of VVZ-149. To demonstrate assay sensitivity, lidocaine will be administered as a positive control.
- Trial name
- LMR (NCT02644421)
- Testing
- VVZ-149, Lidocaine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Brigham and Women's Hospital
Diabetic Neuropathic Pain
A Randomized, Double-blind, Placebo- and Active-controlled Study of the Electric Current Effects of ABT-639 on the Spontaneous Activity of Pain Sensory Receptors in Patients With Diabetic Peripheral Neuropathy
People with diabetes can, over time develop nerve damage throughout the body with symptoms such as pain, tingling, or numbness (loss of feeling) in the hands, arms, feet and legs.
- Trial name
- NCT01589432
- Testing
- ABT-639, Lidocaine
- Where
- United Kingdom
- Volunteers
- 39 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Painful Diabetic Neuropathy
A Trial to Investigate Safety and Efficacy of SPM927 in Painful Diabetic Neuropathy
The primary purpose is to investigate the safety and efficacy of SPM927 in patients with Painful Diabetic Neuropathy
- Trial name
- NCT00861445
- Testing
- SPM927/Lacosamide
- Volunteers
- 119 people
- Sponsor
- UCB Pharma
Carpal Tunnel Syndrome, Pain
Effect of Out of Plane and In Plane Injection Techniques in Patients With Carpal Tunnel Syndrome
The aim of this study, using two different injection techniques, 1. To evaluate the patients in terms of the pain they feel during the application of carpal tunnel syndrome (CTS) injection, 2.
- Conditions
- Carpal Tunnel Syndrome, Pain, Carpal Tunnel
- Trial name
- NCT05343351
- Testing
- Technique of injection method
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Chronic Pain, Neuralgia
Acupuncture Versus Conventional Treatment for Chronic Pain in Patients With Chronic Kidney Disease
This study evaluated acupuncture plus optimized conventional pharmacological treatment compared with optimized conventional pharmacological treatment alone for chronic pain in adults with chronic kidney disease receiving…
- Conditions
- Chronic Pain, Neuralgia, Renal Insufficiency,Chronic
- Trial name
- NCT07891819
- Testing
- Acupuncture, Optimized conventional pharmacological treatment
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- Federal University of São Paulo
Neuralgia, Postherpetic
Effect of Opioids in Neuropathic Pain in Postherpetic Patients
Postherpetic neuralgia (PHN) is often associated with pain and sensory changes and is the leading type of neuropathic pain in modern clinical pain research.
- Trial name
- VHPRG-HDRPH (NCT01102101)
- Testing
- Remifentanil
- Where
- 2 sites in Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Painful Diabetic Peripheral Neuropathy (PDPN), Acupressure
The Effect of Acupressure on Symptoms in Elderly Adults With Painful Diabetic Neuropathy
This project aims to evaluate the effects of acupressure applied to elderly individuals with painful diabetic peripheral neuropathy (DPN) on neuropathic symptoms, balance confidence, fear of falling, and quality of life.
- Trial name
- NCT07392619
- Testing
- acupressure
- Volunteers
- 76 people
- Sponsor
- Nigde Omer Halisdemir University