Clinical trials: Peripheral Neuropathy Pain
Neuropathic Pain, Neuralgia
Study to Evaluate the Efficacy of Lithium Carbonate in Spinal Cord Injury Patients With Neuropathic Pain
To investigate the efficacy of lithium carbonate in the treatment of neuropathic pain of patients with spinal cord injury.
- Conditions
- Neuropathic Pain, Neuralgia, Spinal Cord Injuries
- Trial name
- NCT01855594
- Testing
- Lithium Carbonate
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- China Spinal Cord Injury Network
Lumbar Radiculopathy
Lumber Spine Mobilization and Spinal Traction on Lumber Radiculopathy.
Lumber radiculopathy, also known as sciatica, is a condition that causes pain in the lower back and legs due to irritation or compression of the spinal nerves. group between 20 and 50 years old.
- Trial name
- NCT06339931
- Testing
- SMWLM combined Spinal traction with belt, SMWLM combined spinal traction without belt
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Diabetic Peripheral Neuropathic Pain
Using Cannabidiol to Treat Diabetic Peripheral Neuropathy of the Feet
The purpose of the study is to evaluate whether PG-DN-20WS is a better pain reliever in patients with diabetic neuropathic pain of the feet than a placebo.
- Trial name
- NCT04679545
- Testing
- CBD
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Pure Green
Osteoarthritis Hand, Neuropathic Pain
Capsaicin in Digital Osteoarthritis Versus Control
The objective of this multicentric, randomized controlled double-blind clinical trial is to demonstrate the efficacy of transdermal application of capsaicin in patients with painful digital osteoarthritis with a neuropathic pain…
- Trial name
- CADOR (NCT06444919)
- Testing
- Capsaicin 179 Mg Cutaneous Patch, Capsaicine low dose 0.04 %
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
Neuropathic Pain
Safety And Efficacy In Long Term Use Of Lyrica (Regulatory Post Marketing Commitment Plan)
The objective of this investigation is to evaluate the safety and efficacy of long term use with Lyrica in medical practice. Also, occurrence of unknown and known adverse drug reactions (ADRs) in subjects treated with Lyrica will…
- Trial name
- RAINBOW-L (NCT01279850)
- Testing
- Pregabalin (Lyrica) capsule
- Volunteers
- 891 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Segmental Exclusion Syndrome, Complex Regional Pain Syndrome (CRPS)
Peripersonal Space Representation in Upper Limb Segmental Exclusion
This study aims to evaluate the representation of action peripersonal space (PPS) in subjects suffering from unilateral segmental exclusion syndrome of the upper limb compared to healthy control subjects.
- Conditions
- Segmental Exclusion Syndrome, Complex Regional Pain Syndrome (CRPS), Upper Limb Neglect (Peripheral)
- Trial name
- NCT07349173
- Testing
- Reachability Judgment Task in VR.
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Lumbar Radiculopathy
Effects of Spinal Mobilization With Leg Movement With and Without Neural Flossing Technique in Lumbar Radiculopathy
Lumbar radiculopathy is a spinal condition caused by compression or irritation of the lumbar nerve roots, leading to radiating leg pain, sensory changes, and functional disability.
- Trial name
- NCT07646379
- Testing
- SMWLM along with Neural flossing technique, SMWLM without Neural flossing technique
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Diabetic Peripheral Neuropathic Pain
Diabetic Neuropathic Pain Relief, 6 Weeks Dosage Sublingual Water-soluble CBD/PEA
The purpose of the study is to evaluate whether the DIA/NPR-6 is a better pain reliever in patients with diabetic neuropathic pain of the feet compared to placebo.
- Trial name
- NCT05766969
- Testing
- CBD/PEA
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Pure Green Pharmaceuticals Inc.
Post-Amputation Pain, Phantom Limb Pain
Electrical Stimulation for the Treatment of Post-Amputation Pain Using the SPRINT System
The purpose of this study is to determine if electrical stimulation (small levels of electricity) can safely and effectively reduce post-amputation pain. This study involves a device called the SPRINT System.
- Conditions
- Post-Amputation Pain, Phantom Limb Pain, Residual Limb Pain
- Trial name
- NCT01996254
- Testing
- SPRINT Peripheral Nerve Stimulation (PNS) System
- Where
- 10 sites in United States
- Volunteers
- 28 people
- Sponsor
- SPR Therapeutics, Inc.
Lumbar Radiculopathy
Three-dimensional Lumbar Myofascial Release and Motor Control in Lumbar Radiculopathy
to investigate The Efficacy of three-dimensional lumbar myofascial release with motor control training on back perception and pain in lumbar radiculopathy Patients with lumbar radiculopathy demonstrate impairments in function and…
- Trial name
- NCT06990113
- Testing
- three dimensional lumbar myofascial release, conventional treatment.
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- October 6 University
Complex Regional Pain Syndromes
Impact of the Ultrasound-guided Approach on the Efficiency and Safety of the Stellate Ganglion Block in Chronic Pain
The first purpose of this study is to compare the effectiveness of the stellate ganglion block realized with two different approaches (blind and ultrasound-guided) in patients with a diagnosis of complex regional pain syndrome.
- Trial name
- NCT01954888
- Testing
- Blind technique, Ultrasound-guided technique
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Urethral Stricture
Intraoperative Lidocaine or Dexmedetomidine for Postoperative Pain Modulation After Urethral Reconstruction.
The development of chronic postoperative pain (CPP) following surgery is influenced by several factors, among which the intensity of acute postoperative pain in the immediate perioperative period and mechanisms related to nerve…
- Trial name
- NCT07676942
- Testing
- Perioperative lidocaine infusion, Perioperative dexmedetomidine infusion
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Centre of Postgraduate Medical Education
Chemotherapy-induced Peripheral Neuropathy
A New Method for Identifying Sensory Changes in Painful Chemotherapy-induced Peripheral Neuropathy (CIPN)
The investigators propose that using the Diode Laser fiber type Selective Stimulator (DLss) in patients with chemotherapy-induced peripheral neuropathy (CIPN) will allow for the assessment of changes in small-fiber pain…
- Trial name
- NCT03687970
- Testing
- Brief Pain Inventory, Hospital Anxiety and Depression Scale, Neuropathic Pain Symptom Inventory
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Washington University School of Medicine
Postherpetic Neuralgia
Dorsal Root Ganglion Stimulation in Postherpetic Neuropathy
This is a prospective, multicenter observational study evaluating the efficacy of ganglion stimulation (medical device) in cases of post-herpetic neuropathy.
- Trial name
- DRGs (NCT06225960)
- Where
- Italy
- Volunteers
- 77 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Neuropathic Pain, Magnetic Resonance Imaging
Multimodal MRI for MRgFUS Central Lateral Thalamotomy in Neuropathic Pain
To explore the pathogenesis underlying neuropathic pain as well as the mechanisms of pain relief after Magnetic resonance-guided focused ultrasound (MRgFUS) Central Lateral Thalamotomy through multi-model MRI study, and to…
- Trial name
- NCT05122403
- Testing
- MRgFUS central lateral thalamotomy
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Chinese PLA General Hospital
Back Pain, Neuralgia
Evaluation of Spinal Cord Stimulation Pulse Rate On Clinical Outcomes
Clinical study to estimate the optimal frequency for stimulation of the spinal cord to achieve relief from back pain.
- Trial name
- PROCO (NCT02549183)
- Testing
- Boston Scientific PRECISION Spinal Cord Stimulator System
- Where
- 3 sites in United Kingdom
- Volunteers
- 22 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Diabetic Neuropathies, Chronic Pain
Optimization of NIBS for Diabetic Neuropathy Neuropathic Pain
The purpose of this study is to assess the effects of Transcranial Direct Current Stimulation (tDCS) in combination with Transcranial ultrasound (TUS) for the treatment of pain and functional limitations in subjects with Diabetic…
- Trial name
- NCT03625752
- Testing
- Active Comparator: Active tDCS + Active TUS
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Case Western Reserve University
Complex Regional Pain Syndrome Type I (CRPS-I), Distal Radius Fracture
ESWT for CRPS-I After Distal Radius Fracture
Complex regional pain syndrome type I (CRPS-I) can develop after a distal radius fracture and may cause persistent pain, swelling, limited wrist and hand movement, and difficulty using the affected upper limb.
- Trial name
- CRPS-ESWT (NCT07807852)
- Testing
- Active ESWT will be applied once weekly for a total of five sessions to the affected distal forearm, wrist, and painful soft-tissue areas.Associated Arm: Standard Rehabilitation + Active ESWT, Standard Rehabilitation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dilek ün oguzhanasilturk
Neuropathic Pain
Efficacy of Perioperative Pregabalin in Reducing the Incidence of Chronic Neuropathic Pain and Postthoracotomy Syndrome.
This study is designed to assess: 1. The impact of taking perioperative pregabalin on the incidence of chronic neuropathic pain and postthoracotomy syndrome at 3 months in patients who have undergone a thoracotomy with a thoracic…
- Trial name
- NCT00967135
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
RSD (Reflex Sympathetic Dystrophy), Algodystrophy
Prophylactic Administration of Vitamin C in Wrist Fractures
Complex Regional Pain Syndrome or posttraumatic dystrophy is a pain syndrome which develops after a trauma, surgery or for unknown reason. The incidence after wrist fractures varies in literature from 2 - 37%.
- Conditions
- RSD (Reflex Sympathetic Dystrophy), Algodystrophy, CRPS Type I
- Trial name
- NCT00296868
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Stichting Achmea Slachtoffer en Samenleving
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