Clinical trials: Peripheral Neuropathy Pain
Healthy Volunteers, Patients Suffering of Peripheral Neuropathic Pain
Study of Integrity of Down Inhibitor Bundle at Patients Suffering of Neuropathic Pain
Several studies showed that activity of down inhibitor bundle is weakened in different painful pathologies as the fibromyalgy or the trigeminal nevralgy.
- Trial name
- PhyDoNe (NCT01053845)
- Testing
- Neuropathic pain
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Neuropathic Pain, Spinal Cord Injury
Effectiveness of Controlled-Release Morphine for Chronic Neuropathic Pain After Spinal Cord Injury
We would like to learn if a medicine called "modified-release morphine sulfate" (Avinza) helps reduce Spinal Cord Injury (SCI)-related pain that has lasted a long time.
- Trial name
- NCT00488969
- Testing
- Modified-release morphine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Idiopathic Axonal Polyneuropathy
Phenytoin Cream for the Treatment of Neuropathic Pain
Objectives: The main objective is to evaluate the efficacy and safety of phenytoin cream in patients with neuropathic pain due to chronic idiopathic axonal polyneuropathy (CIAP).
- Trial name
- EPHENE (NCT04647877)
- Testing
- phenytoin cream
- Where
- Netherlands
- Volunteers
- 81 people
- Sponsor
- David J. Kopsky
Neuropathic Pain
Structural and Functional Brain Reorganization in Neuropathic Pain. Influences of the Loss of Sensitivity and the Atrophy Cortical on Activations Due to Stimulation Allodynic
Neuropathic pain is a medical condition involving allodynia (painful perceptions in response to stimuli that normally are not) and spontaneous pain (occurring at rest, without stimulation).
- Trial name
- ALLO (NCT02858479)
- Testing
- stimulation on painful area (area allodynic), same stimulation on non-painful area, MRI scan
- Where
- France
- Volunteers
- 41 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
CIPN - Chemotherapy-Induced Peripheral Neuropathy, Age Over 18
Sensory Rehabilitation in Chemo Induced Peripheral Neuropathy
This study is a cross-over RCT evaluating the effectiveness of 3 sessions a week apart of explicit sensory retraining to the lower extremities in individuals with CIPN versus usual care.
- Conditions
- CIPN - Chemotherapy-Induced Peripheral Neuropathy, Age Over 18, Chemotherapy-induced Peripheral Neuropathy
- Trial name
- NCT06724861
- Testing
- Explicit Sensory Retraining for the lower extremities, no treatment
- Where
- Israel
- Volunteers
- 27 people
- Sponsor
- Assaf-Harofeh Medical Center
Pudendal Nerve, Healthy Women
Pelvic Floor Shear-Wave Elastography in Healthy and Pudendal Neuralgia Women
This study will compare superficial pelvic floor shear-wave elastography between healthy women and women with pudendal neuralgia.
- Trial name
- ELANEP (NCT07458737)
- Testing
- Pelvic floor shear wave elastography, Pelvic Floor Impact Questionnaire-Short Form 7 (PFIQ-7), Female Sexual Distress Scale-Revised (FSDS-R)
- Where
- Slovakia
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Comenius University
Radiculopathy
Presentation of Lumbar Disc and Reduction of Symptoms
The trial aims to assess the hypothesis that presentation of the disc material to the patient following a lumbar microdiscectomy would positively influence the improvement in their leg and back symptoms.
- Trial name
- POLDAROS (NCT00440856)
- Testing
- Presentation of excised intervertebral disc fragments
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Cervical Radiculopathy
Effects of Neural Glides Versus Proprioceptive Neuromuscular Facilitation in Cervical Radiculopathy
this project was a Quasi-Experimental Trial. conducted to compare the Effects of Neural Glides Versus Proprioceptive Neuromuscular Facilitation in Terms of Joint Position Sense and Pain in Cervical Radiculopathy .
- Trial name
- NCT04824170
- Testing
- Neural Glide, Rhythmic stabilization technique
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Lumbosacral Radiculopathy, McKenzie Derangement Syndrome
Effect of Combined Lumbar Traction and Repetitive Back Extension Exercise on H-reflex in Lumbosacral Radiculopathy
The aim of the study is to investigate the effect of performing combined lumbar traction and repeated back extension exercise (McKenzie) on soleus H-reflex, pain, and disability in patients with lumbosacral radiculopathy.
- Trial name
- NCT06216288
- Testing
- Repeated back extension exercise (McKenzie), Mechanical traction
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Diabetic Neuropathy
FDGL Dose-Finding Study for Diabetic Neuropathy
This study investigates the optimal dose of fermented deglycyrrhizinated licorice (FDGL) that maximizes both safety and efficacy in managing diabetic neuropathy complications in adults.
- Trial name
- NCT07117942
- Testing
- Fermented Deglycyrrhizinated Licorice (FDGL)
- Where
- Egypt
- Volunteers
- 485 people
- Sponsor
- Helwan University
Lumbar Radiculopathy
Effects of Adding Balneotherapy to a Physical Therapy Program in Patients With Chronic Lumbar Radiculopathy
The aim of this study is to investigate the effects of adding balneotherapy to the conventional physical therapy program on neuropathic pain, disability, daily living activities, and sleep quality in patients with chronic lumbar…
- Trial name
- NCT06846970
- Testing
- Experimental, Active Comparator
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Afyonkarahisar Health Sciences University
Diabetic Peripheral Neuropathy, Nerve Pain
The Effect of Pregabalin on Pain Related to Walking in Patients With Diabetic Peripheral Neuropathy
The hypothesis of this study is that pregabalin, 150 mg bid, will reduce general daytime pain in patients diagnosed with diabetic peripheral neuropathy and that it will also reduce the level of pain associated with walking.
- Trial name
- NCT02927951
- Testing
- Pregabalin
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Eastern Virginia Medical School
Chronic Pain, Nociceptive Pain
Central Sensitisation in Nociceptive and Neuropathic Pain
This study aims to investigate differences in central sensitization among patients with chronic nociceptive pain, neuropathic pain, and mixed pain conditions.
- Conditions
- Chronic Pain, Nociceptive Pain, Neuropathic Pain, Mixed Pain (Nociceptive and Neuropathic)
- Trial name
- ALGOS (NCT07321080)
- Testing
- Neuropsychological assessment, Laser evoked potentials
- Where
- Italy
- Volunteers
- 185 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Low Back Pain, Radicular Syndrome
Comparison of High-Intensity and Conventional Physical Therapy in Musculoskeletal Disorders
This pilot randomized controlled trial aims to compare the clinical effectiveness of advanced high-intensity physical therapy modalities with conventional physical therapy in patients suffering from musculoskeletal disorders.
- Conditions
- Low Back Pain, Radicular Syndrome, Sacroiliac Joint Dysfunction, Shoulder Impingement Syndrome
- Trial name
- NCT07903142
- Testing
- Repetitive Peripheral Magnetic Stimulation (rPMS), High-Intensity Laser Therapy (HIL), Extracorporeal Shockwave Therapy (ESWT)
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- BTL Industries Ltd.
Painful Diabetic Neuropathy
Trazodone in Painful Diabetic Neuropathy
The aim of the study is to collect preliminary information on the effect of low doses of trazodone on pain intensity in patients with painful diabetic neuropathy and to evaluate the neuropathic pain symptoms, anxiety, sleep…
- Trial name
- NCT03202979
- Testing
- Trazodone 20 mg, Trazodone 10 mg
- Where
- 20 sites in Czechia, Hungary and 1 more
- Volunteers
- 142 people
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Neuralgia, Shingles
Dose-Finding Study of REN-1654 in Patients With Post-Herpetic Neuralgia
The purpose of this study is to gain initial safety and efficacy data on the experimental agent REN-1654 in patients with painful post-herpetic neuralgia (PHN).
- Conditions
- Neuralgia, Shingles, Peripheral Nervous System Disease
- Trial name
- NCT00099528
- Testing
- REN-1654
- Where
- 16 sites in United States
- Volunteers
- 90 people
- Sponsor
- Renovis
Diabetic Peripheral Neuropathic Pain, Diabetic Peripheral Neuropathy
Efficacy and Safety of ETX-018810 for the Treatment of Diabetic Peripheral Neuropathic Pain
A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Parallel-Group Study to Evaluate the Efficacy and Safety of ETX 018810 in Subjects with Diabetic Peripheral Neuropathic Pain.
- Trial name
- NCT04688671
- Testing
- ETX-018810
- Where
- 22 sites in United States
- Volunteers
- 167 people
- Sponsor
- Eliem Therapeutics (UK) Ltd.
Neuralgia, Neuralgia, Postherpetic
A Study Of The Efficacy Of Gabapentin In Neuropathic Pain Patients As Measured By Quantitative Sensory Testing
The purpose of this study is to assess the reproducibility and the effect of gabapentin on quantitative sensory testing assessments in neuropathic pain subjects.
- Trial name
- NCT00674687
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Postoperative Pain, Carpal Tunnel Release
Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries
The purpose of this study is to determine the efficacy of intra-operative administration of IV tylenol and/or IV toradol in minimizing post-operative pain for carpal tunnel patients and distal radius fracture patients.
- Conditions
- Postoperative Pain, Carpal Tunnel Release, Distal Radius Fracture
- Trial name
- NCT02313675
- Testing
- Acetaminophen, Ketorolac Tromethamine, Saline
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- John Fowler
Post-Herpetic Neuralgia, Acute Herpes Zoster
Evolution of Pain From Herpes Zoster
Evolution of pain and neural injury will be evaluated at 2 years or longer after the onset of AHZ by multiple measures. Assessments at 2 years or longer will be compared to those collected during the first 6 months after HZ in…
- Trial name
- NCT00305357
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
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