Clinical trials: Peripheral Neuropathy Pain
HIV, Peripheral Neuropathy
OPEN Study: Pain Management Treatment Needs Interviews
Presently, there are few options for medically managing HIV-related painful peripheral sensory neuropathy (HIV-SN). Psychological treatments, including Cognitive Behavioural Therapy (CBT), represent a potentially viable addition…
- Trial name
- NCT02972606
- Where
- 2 sites in United Kingdom
- Volunteers
- 26 people
- Sponsor
- King's College London
Neuralgia
Evaluating E2007 (Perampanel) in Patients With Painful Diabetic Neuropathy (PDN) or Post-Herpetic Neuralgia (PHN)
The purpose of this study is to evaluate the safety, tolerability and continued efficacy of perampanel in patients previously enrolled in double-blind, placebo-controlled studies for Painful Diabetic Neuropathy (PDN) or…
- Trial name
- NCT00592904
- Testing
- E2007
- Where
- United States
- Volunteers
- 262 people
- Sponsor
- Eisai Inc.
Burning Pain, Impaired Balance
Feasibility Study of New Method of Diagnostic and Prediction of Painful CIPN
This clinical trial studies how well Diode laser fiber type Selective Stimulator (DLss) works in predicting pain development in patients with ovarian cancer who are receiving chemotherapy.
- Conditions
- Burning Pain, Impaired Balance, Malignant Ovarian Neoplasm, Numbness
- Trial name
- NCT03206216
- Testing
- Diode Laser fiber type Selective Stimulator (DLss)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stanford University
Neuropathic Pain, Diabetic Peripheral Neuropathy (DPN)
Oral LAT8881 in Neuropathic Pain
This is a randomised, placebo-controlled, double-blind, crossover, phase IIa study to investigate the efficacy and safety of oral LAT8881 in neuropathic pain.
- Conditions
- Neuropathic Pain, Diabetic Peripheral Neuropathy (DPN), Post Herpetic Neuralgia (PHN)
- Trial name
- NCT03865953
- Testing
- LAT8881
- Where
- 6 sites in Australia, United Kingdom
- Volunteers
- 53 people
- Sponsor
- Lateral Pharma Pty Ltd
Diabetic Neuropathy, Painful
Randomized, Double-Blind, Multicenter, Placebo-Controlled Study Of Pregabalin For Pain Associated With Diabetic Peripheral Neuropathy
To evaluate the efficacy and safety of pregabalin at 300 mg/day and 600 mg/day (BID) in patients with painful diabetic peripheral neuropathy.
- Trial name
- NCT00553475
- Testing
- pregabalin
- Where
- 49 sites in Japan
- Volunteers
- 314 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Postherpetic Neuralgia
Efficacy and Safety of LX9211 in Participants With Postherpetic Neuralgia
Evaluation of the efficacy of LX9211 compared to placebo in reducing pain related to postherpetic neuralgia over an 11 week assessment period.
- Trial name
- RELIEF-PHN1 (NCT04662281)
- Testing
- LX9211
- Where
- 32 sites in United States, Czechia and 1 more
- Volunteers
- 79 people
- Sponsor
- Lexicon Pharmaceuticals
HIV Infections, Peripheral Neuropathy
Combination Pain Therapy in HIV Neuropathy
Neuropathy results from damage to the nerves in the feet and legs. It is usually experienced as pain, tingling or numbness. In HIV-infected people, neuropathy can result from the infection itself or be a side effect of…
- Trial name
- NCT00863057
- Testing
- Duloxetine, Methadone
- Where
- 8 sites in United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Diabetic Peripheral Neuropathic Pain (DPN), Postherpetic Neuralgia (PHN)
Pregabalin Treatment Of Peripheral Neuropathic Pain Associated With Diabetic Peripheral NeP (DPN), Postherpetic Neuralgia (PHN), HIV-related NeP (HIV), and Chemotherapy Induced NeP
Management of neuropathic pain associated with diabetic peripheral neuropathy, post-herpetic neuralgia, human immunodeficiency virus-related peripheral neuropathy, and chemotherapy induced peripheral neuropathy.
- Conditions
- Diabetic Peripheral Neuropathic Pain (DPN), Postherpetic Neuralgia (PHN), HIV-related Neuropathic Pain (HIV), Chemotherapy Induced Neuropathic Pain
- Trial name
- NCT00407511
- Testing
- Pregabalin
- Where
- 11 sites in Colombia, Ecuador and 3 more
- Volunteers
- 121 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Neuralgia
Dose-Tolerability Titration Study to Evaluate The Efficacy And Safety Of Perampanel (E2007) In Patients With Post-Herpetic Neuralgia (PHN)
The purpose of the study is to determine the efficacy and safety of Perampanel (E2007) in patients with Post-Herpetic Neuralgia (PHN).
- Trial name
- NCT00592774
- Testing
- E2007 (perampanel)
- Where
- 47 sites in United States, Canada
- Volunteers
- 146 people
- Sponsor
- Eisai Inc.
Painful Diabetic Peripheral Neuropathy
Ricolinostat in Patients With Painful Diabetic Peripheral Neuropathy
This is a randomized, double-blind, 2-arm, parallel group study of up to 274 evaluable patients designed to evaluate the safety and efficacy of the histone deacetylase 6 (HDAC6) inhibitor ricolinostat for painful DPN.
- Trial name
- NCT03176472
- Testing
- ricolinostat
- Where
- 35 sites in United States
- Volunteers
- 282 people
- Sponsor
- Regenacy Pharmaceuticals LLC
Postherpetic Neuralgia ( PHN )
Pregabalin for Treatment of Patients With Postherpetic Neuralgia (PHN)
To prove pregabalin is effective in relieving pain compared with placebo in subjects with postherpetic neuralgia (PHN).
- Trial name
- NCT01455428
- Testing
- Lyrica (pregabalin)
- Where
- 22 sites in China
- Volunteers
- 223 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Postherpetic Neuralgia
Study to Assess the Efficacy, Safety, and Tolerability of ADL5747 in Participants With Postherpetic Neuralgia
The primary purpose of this study is to evaluate the analgesic efficacy of ADL5747 in participants with postherpetic neuralgia (PHN).
- Trial name
- NCT01058642
- Testing
- ADL5747, Pregabalin
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Carpal Tunnel Syndrome
Comparison of Two Techniques for the Treatment of Carpal Tunnel Syndrome
The main objective of this study is to compare the complete section of the transverse carpal ligament with another median nerve release technique and to determine if the incidence of post-surgical pillar pain is lower for either…
- Trial name
- STCCOT (NCT05468814)
- Testing
- Z-plasty, Conventional
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Hospital Universitario Reina Sofia de Cordoba
Neuropathy, Diabetic, Neuropathy;Peripheral
Clinical Efficacy and Human Factors Validation Testing of the Erchonia EVRL for Providing Temporary Relief of Diabetic Peripheral Neuropathy Foot Pain
The purpose of this clinical study is to determine the effectiveness of the Erchonia® EVRL™, manufactured by Erchonia Corporation (the Company), in providing prescription home use application for temporary relief of diabetic…
- Conditions
- Neuropathy, Diabetic, Neuropathy;Peripheral, Neuropathy, Painful
- Trial name
- NCT05291975
- Testing
- Erchonia® EVRL™
- Where
- 4 sites in United States
- Volunteers
- 64 people
- Sponsor
- Erchonia Corporation
Sciatica
Effectiveness of Oral Prednisone in Improving Physical Functioning and Decreasing Pain in People With Sciatica
Sciatica is a condition that causes a sharp, burning pain in the back, buttock, and leg. The condition is caused by injury to or compression of the sciatic nerve, which is located in the back of the leg.
- Trial name
- ACT FAST (NCT00668434)
- Testing
- Prednisone
- Where
- 3 sites in United States
- Volunteers
- 269 people
- Sponsor
- Kaiser Permanente
Chronic Pain, Failed Back Surgery Syndrome
Sensory Testing of Multiple Forms of Spinal Cord Stimulation for Pain
Doctors sometimes treat chronic pain with devices that send mild electrical currents into the spinal cord. This type of treatment is referred to as neurostimulation.
- Conditions
- Chronic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes, Neuropathic Pain
- Trial name
- NCT04732325
- Testing
- Spinal cord stimulation
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Michigan
Pain, Peripheral Neuropathy
MC5-A Scrambler Therapy in Reducing Peripheral Neuropathy Caused by Chemotherapy
RATIONALE: Scrambler therapy may help relieve pain from peripheral neuropathy caused by chemotherapy. PURPOSE: This phase II trial is studying how well MC5-A scrambler therapy works in reducing peripheral neuropathy caused by…
- Trial name
- NCT01290224
- Testing
- scrambler therapy, questionnaire administration
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Neuropathy, Diabetic
A Study In Patients With Neuropathic Pain From Diabetic Peripheral Neuropathy (DPN)
The purpose of this study is to determine whether gabapentin enacarbil (XP13512/GSK1838262), hereafter referred to as GEn is effective in the treatment of neuropathic pain associated with diabetic peripheral neuropathy(DPN)
- Trial name
- NCT00643760
- Testing
- GEn 1200mg/day, GEn 2400mg/day, GEn 3600mg/day
- Where
- 90 sites in United States
- Volunteers
- 421 people
- Sponsor
- XenoPort, Inc.
Diabetic Peripheral Neuropathy, Diabetes
Efficacy, Safety, and PK of LX9211 in Participants With Diabetic Peripheral Neuropathic Pain
Evaluation of the efficacy of a low and high dose of LX9211 compared to placebo in reducing pain related to diabetic peripheral neuropathy (DPNP) over an 11 week assessment period.
- Trial name
- RELIEF-DPN 1 (NCT04455633)
- Testing
- LX9211
- Where
- 44 sites in United States
- Volunteers
- 319 people
- Sponsor
- Lexicon Pharmaceuticals
Neuropathic Pain
A Study to Investigate the Analgesic Efficacy of AZD2423 Compared With Placebo After 28 Days Treatment in Patients With Painful Diabetic Polyneuropathy
A study to investigate the analgesic efficacy of AZD2423 compared with placebo after 28 days treatment in patients with painful diabetic polyneuropathy.
- Trial name
- NCT01201317
- Testing
- AZD2423
- Where
- 20 sites in United States, Canada
- Volunteers
- 134 people
- Sponsor
- AstraZeneca