Clinical trials: Peripheral Neuropathy With Type 2 Diabetes
Diabetic Foot, Diabetes Mellitus, Type 2
Foot-Ankle Exercise and Walking Exercise on Diabetes Mellitus Patients
The primary purpose of this study is to determine the effectiveness of foot-ankle exercise and walking exercise on foot neuropathy, stress, and quality of life (QoL) among people with diabetes mellitus (PWDM).
- Conditions
- Diabetic Foot, Diabetes Mellitus, Type 2, Diabetic Neuropathies, Diabetes Type 2
- Trial name
- NCT06518486
- Testing
- Foot-ankle exercise, Walking exercise, Usual care and health education
- Where
- 5 sites in Indonesia
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Diabetic Neuropathy
Exercise and Nerve Function in Diabetes
The purpose of this study is to describe the effect of a 10-week exercise program on nerve function and number of nerve fibers in the skin in the lower leg in people with diabetic neuropathy.
- Trial name
- NCT00970060
- Testing
- Exercise
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Patricia Kluding, PhD
Diabete Type 2, Diabetic Foot
Prevalence of the Appearance of Diabetic Ulcers in Patients With 3D Insole and LSCI.
Diabetes is a serious and chronic disease that affects more than 347 million people in the world. It is the leading cause of death by age and its prevalence is increasing annually throughout the world.
- Conditions
- Diabete Type 2, Diabetic Foot, Neuropathy, Diabetic, Vascular Disease, Peripheral
- Trial name
- MYFOOT-C (NCT05843929)
- Testing
- LSCI
- Volunteers
- 86 people
- Sponsor
- Esther Soler
Diabetic Neuropathies, Diabetes Mellitus (Type 2)
Effect of 4-7-8 Breathing Technique on Pain and Anxiety During Electromyography in Diabetic Neuropathy
This study aims to determine the effect of the 4-7-8 breathing technique, applied during Electromyography (EMG) for the diagnosis of diabetic peripheral neuropathy, on the pain and anxiety levels experienced by patients with Type…
- Conditions
- Diabetic Neuropathies, Diabetes Mellitus (Type 2), Pain, Anxiety
- Trial name
- NCT07702175
- Testing
- 4-7-8 Breathing Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Nurgül Gün
Diabetes Mellitus, With Complications
Effects of Pulsatile Insulin Delivery on Diabetic Neuropathy in Patients With Types 1 and 2 Diabetes Mellitus
Diabetic neuropathy is a progressive complication causing serious problems in 25-40% of diabetic patients. Anecdotal reports have indicated improvement with pulsatile IV insulin in patients otherwise resistant to all conventional…
- Trial name
- NCT00228891
- Testing
- Effect of Pulsatile IV insulin on diabetic neuropathy
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Florida Atlantic University
Chronic Cough, Type 2 Diabetes
Chronic Cough and Small Fiber Neuropathy
Diabetic patients with and without chronic cough will be included in this study. After giving their informed consent, the patients will perform a spirometry, chest X-ray at the inclusion visit.
- Trial name
- CHROCOS (NCT03787511)
- Testing
- Cough assessment, Neurological tests and cardiovascular tests, Skin biopsy
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Toulouse
Diabetic Neuropathy Peripheral
Evaluation and Treatment for Diabetic Peripheral Neuropathy
This study aims: To compare conventional diabetic neuropathy screening techniques with user-friendly technological equipment; To evaluate the effects of the combined application of laser and therapeutic ultrasound in the…
- Trial name
- NCT07317284
- Testing
- Active Comparator
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Diabetes Mellitus, Type 2, Neuropathic Pain
Effect of a Combined Exercise Program on Neuropathic Pain and Perceived Quality of Life in Type 2 Diabetes
Therapeutic exercise is one of the therapies used as a treatment for diabetic neuropathy, which is a complication of diabetes. In order to reduce pain and improve the perception of quality of life, a combined therapeutic exercise…
- Conditions
- Diabetes Mellitus, Type 2, Neuropathic Pain, Neuropathy, Diabetic
- Trial name
- NCT05703152
- Testing
- Combined Exercise
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- Maria Gabriela Aké Palomo
Coronary Disease, Myocardial Infarction
Chronical Illness-related Limitations of the Ability to Cope with Rising Temperatures: an Observational Study, 2nd Wave
The CLIMATE-II Observational Study examines to what extent chronically ill patients experience adverse health effects because of heat and whether the patients' specific health behavior, somatosensory amplification, risk and…
- Conditions
- Coronary Disease, Myocardial Infarction, Heart Failure, Arrhythmias, Cardiac
- Trial name
- CLIMATE-II (NCT06407154)
- Where
- Germany
- Volunteers
- 578 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Diabetes
Effect of Flavanol-rich Cocoa on Peripheral and Cerebral Blood Flow in Type 2 Diabetes
Cocoa flavanols form part of the family of chemicals (also found in red wine and tea) which have aroused interest due to population studies suggesting that diets high in these substances might reduce risks of heart disease.
- Trial name
- NCT01654172
- Testing
- High Flavanol Cocoa, Low Flavanol Cocoa
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University of Nottingham
Neuropathy Autonomic, Cardiac Autonomic Neuropathy
Diabetic Neuropathy Rapid Screening Test in Turkish Patients With Type 2 Diabetes: Sudoscan
Neuropathy is a frequently observed complication occurring in 60-70% of diabetic patients throughout their lives. In addition, neuropathy is a severe disease that progresses insidiously; its diagnosis can be delayed due to the…
- Conditions
- Neuropathy Autonomic, Cardiac Autonomic Neuropathy, Type2Diabetes, Diabetic Neuropathy Peripheral
- Trial name
- NCT05299918
- Volunteers
- 437 people
- Sponsor
- Istanbul University
DIABETES, DIABETIC RETINOPATHY
PRELIMINARY EVALUATION OF PHARMACOLOGICAL LOWERING OF AGEs
There is evidence of the association between diabetic microangiopathy and elevated serum concentrations of advanced glycation end-products (AGEs).
- Conditions
- DIABETES, DIABETIC RETINOPATHY, DIABETIC NEUROPATHY
- Trial name
- PREL-AGES (NCT02249897)
- Testing
- CHOLESTYRAMINE
- Where
- 2 sites in Chile
- Volunteers
- 7 people
- Sponsor
- University of Chile
Foot Ulcers, Arteriosclerosis Obliterans
HELP-Apheresis in Diabetic Ischemic Foot Treatment (H.A.D.I.F)
Diabetic foot (DF) is a common, severe and costly complication of diabetes. DF is underlied by neuropathy, atherosclerosis of distal arteries and infection, which result in tissue ulcers and necrosis.
- Conditions
- Foot Ulcers, Arteriosclerosis Obliterans, Diabetes Mellitus
- Trial name
- HADIF (NCT01518205)
- Testing
- LDL-apheresis
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Universita di Verona
Pain, Pain Syndrome
Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy
Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates…
- Conditions
- Pain, Pain Syndrome, Pain, Chronic, Chronic Pain
- Trial name
- NCT06072573
- Testing
- Adezunap (AP707)
- Where
- Germany
- Volunteers
- 558 people
- Sponsor
- Apurano Pharmaceuticals GmbH
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Stem Cell Mobilization in Diabetic Neuropathy Subjects Receiving SB-509
The primary and secondary objectives of this study are: Primary: To evaluate stem-cell-mobilization in subjects with diabetic neuropathy receiving SB-509.
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetic Polyneuropathy
- Trial name
- NCT00665145
- Testing
- SB-509
- Where
- 4 sites in United States
- Volunteers
- 23 people
- Sponsor
- Sangamo Therapeutics
Diabetic Neuropathy, Cognitive Impairment
Neuroprotection by Tocotrienols in Type 1 and Type 2 Diabetes Mellitus
Given that the tocotrienols have been shown to possess neuroprotective effects and that both type 1 and type 2 diabetes can lead to peripheral neuropathy and cognitive impairment, the present study aims to determine the…
- Trial name
- VENUS (NCT01973400)
- Testing
- Tocotrienol
- Where
- Malaysia
- Volunteers
- 300 people
- Sponsor
- Universiti Sains Malaysia
Diabetic Neuropathy Peripheral, Activities of Daily Living
Prevalence of Peripheral Neuropathy and Its Impact on Activities of Daily Living in Patients With Type 2 Diabetes
The trend of diabetes prevalence was increased by comparing these two national surveys in 2009 and 2014. However, the studies only focused on the prevalence and risk of diabetes and non-communicable diseases in Myanmar.
- Trial name
- NCT03440203
- Testing
- difficult activities of daily living in each group
- Where
- Japan
- Volunteers
- 975 people
- Sponsor
- Okayama University
Diabetes Mellitus, Type 2, Peripheral Neuropathy
Effectiveness of Foot Exercise People With Type 2 Diabetes
The aim of this study will to investigate the effect of foot exercises in patients with type 2 diabetic and peripheral neuropathy. Subjects will be randomly allocated to either the control or intervention group.
- Trial name
- NCT04064996
- Testing
- Routine rehabilitation program patient education, Routine rehabilitation program + foot exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul University
Coronary Disease, Myocardial Infarction
Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures, Third Wave
The CLIMATE-III Observational Study examines to what extent chronically ill patients experience adverse health effects because of heat and whether the patients' specific health behavior, somatosensory amplification, risk and…
- Conditions
- Coronary Disease, Myocardial Infarction, Heart Failure, Arrhythmias, Cardiac
- Trial name
- CLIMATE-III (NCT06890208)
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 176 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Hypertriglyceridemia, Diabetic Neuropathy
Lovaza® and Microvascular Function in Type 2 Diabetes
The objective of this study is to determine the efficacy of 6 months of 4 g/day oral Lovaza® on endothelial-dependent and heat-induced vasodilation in type 2 diabetics with neuropathy and elevated triglyceride levels.
- Trial name
- NCT00931879
- Testing
- omega-3-ethyl esters
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Eastern Virginia Medical School