Clinical trials: Peripheral Vascular Disease (PVD)
Peripheral Arterial Disease
The Impact of Factor Xa Inhibition on Thrombosis, Platelet Activation, and Endothelial Function in Peripheral Artery Disease
The purpose of this study is to understand how the drug rivaroxaban improves symptoms associated with peripheral artery disease.
- Trial name
- NCT05009862
- Testing
- Rivaroxaban 2.5 Mg Oral Tablet, Aspirin 81Mg Ec Tab
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vanderbilt University Medical Center
Peripheral Arterial Disease
Ankle Arterial Doppler Waveform Assessment For Surveillance Following Lower Limb Revascularisation
The goal of this observational study is to determine the diagnostic performance of serial ankle arterial Doppler waveform assessments in detecting significant arterial restenosis in patients with Peripheral Arterial Disease (PAD)…
- Trial name
- WAVE (NCT06619223)
- Testing
- Duplex Ultrasound
- Volunteers
- 121 people
- Sponsor
- Imperial College London
Peripheral Artery Disease
Community Walking Exercise for Patients With Peripheral Artery Disease
The primary aim of the study is to determine the effect of a community-based walking exercise program with detailed training, monitoring, and coaching (TMC) exercise components enhanced by community-based participatory research…
- Trial name
- GAIT (NCT02075502)
- Testing
- Exercise therapy, lower extremity ET, peripheral open intervention
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Minnesota
Chronic Limb-Threatening Ischemia
Colchicine in Chronic Limb-Threatening Ischemia
Chronic limb-threatening ischemia (CLTI) is the most severe form of peripheral artery disease, a condition in which narrowed or blocked arteries reduce blood flow to the legs.
- Trial name
- CIRCLE-Asia (NCT07536373)
- Testing
- Colchicine 0.5 MG Oral Tablet Once Daily
- Where
- 5 sites in Taiwan
- Volunteers
- 200 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Type 2 Diabetes, Peripheral Vascular Disease
The Effect of a Diabetes Action Team in Patients Post Infrainguinal Bypass Surgery With and Without Diabetes
Diabetes is a very common illness. Approximately 4% of British Columbians have diabetes. However, at least 20% of people admitted to acute care hospitals have diabetes.
- Trial name
- NCT00456105
- Testing
- Subjects with diabetes who plan to undergo elective infrainguinal bypass surgery will receive standard diabetes care by their admitting physician, Subjects with diabetes who plan to undergo elective infrainguinal bypass surgery will receive diabetes care under the direction of the Diabetes Action Team, Subjects without diabetes will have their blood glucose levels monitored while in the hospital
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of British Columbia
Iliac Vein Compression Syndrome
Comparison of Intravascular Ultrasound With Venography in the Diagnosis and Treatment of Iliac Vein Compression Syndrome
The aim of this study is to compare intravascular ultrasound with venography in the diagnosis and treatment of iliac vein compression syndrome.
- Trial name
- NCT03309969
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Zhongshan Hospital
Femoropopliteal Artery Occlusion
Outcome of Endovascular Therapies in Chronic Femoropopliteal Occlusive Disease With Severe Calcification
This study is a prospective, multicenter, real world, observational study, which aims at evaluating the safety, efficacy and economic cost of endovascular treatments for endovascular therapies in chronic femoropopliteal occlusive…
- Trial name
- NCT04716361
- Where
- China
- Volunteers
- 600 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Peripheral Artery Disease (PAD), Intermittent Claudication
Daily Stretching to Improve Walking in Older Patients With Peripheral Artery Disease: The STRETCH PAD Study
The goal of this multi-center clinical trial is to assess the effects of passive calf muscle stretching in older adults diagnosed with peripheral artery disease (PAD). The main questions it aims to answer are: 1.
- Trial name
- STRETCH PAD (NCT07919483)
- Testing
- Therapeutic calf stretching
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Penn State University
Peripheral Vascular Disease
Crossover Study With MultiHance vs a Comparator for Peripheral MRA
This is a double blind crossover study designed to compare two different gadolinium products given at the same dose to patients undergoing MRA assessment of lower legs for the evaluation of peripheral steno-occlusive disease.
- Trial name
- NCT00408083
- Testing
- MultiHance, Magnevist
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Bracco Diagnostics, Inc
Atherosclerosis, Coronary Disease
Natural History of Peripheral Arterial Disease
The Veterans Administration Patient Study examined the progression of peripheral arterial disease (PAD) in patients with large vessel PAD or isolated small vessel PAD.
- Conditions
- Atherosclerosis, Coronary Disease, Arterial Occlusive Diseases, Peripheral Vascular Diseases
- Trial name
- NCT00005254
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Peripheral Vascular Diseases
Comparison Study of Vasovist® Magnetic Resonance Angiography (MRA) and an MRA With a Conventional Extracellular Contrast Agent With X-ray Angiography in Patients With Peripheral Artery Disease
The particular aim of this study is the comparison of the diagnostic results of MRA images upon application of Vasovist (gadofosveset), a contrast agent not yet available on the market, with the MRA images upon application of a…
- Trial name
- NCT00296855
- Testing
- Vasovist (BAY86-5283, MS-325)
- Where
- 26 sites in Argentina, Austria and 4 more
- Volunteers
- 261 people
- Sponsor
- Bayer
Cardiovascular Diseases, Peripheral Vascular Diseases
L-Arginine in the Treatment of Peripheral Arterial Disease
To assess the effects of L-arginine upon functional status (treadmill exercise testing; quality of life) and limb blood (by mercury strain gauge plethysmography) in peripheral arterial disease.
- Trial name
- NCT00284076
- Testing
- L-arginine
- Sponsor
- Stanford University
Myocardial Infarction, Peripheral Vascular Disease
Lowering the Risk of Operative Complications Using Atorvastatin Loading Dose
Patients submitted to noncardiac surgeries are at increased risk of serious cardiovascular complications. Statins have shown to lower cholesterol levels and reduce cardiovascular events in other scenarios.
- Conditions
- Myocardial Infarction, Peripheral Vascular Disease, Aortic Aneurism
- Trial name
- LOAD (NCT01543555)
- Testing
- Atorvastatin
- Where
- Brazil
- Volunteers
- 648 people
- Sponsor
- Hospital do Coracao
Venous Thromboembolic Disease
Comparative Study of the Hemorrhagic Risk in Patients Over 75 Years of Age Taking Enoxaparin
Elderly subjects are at greater risk of thrombophlebitis than the general population, but also of bleeding when anticoagulant therapy is initiated.
- Trial name
- ENOX-VTD-H (NCT05150314)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Strasbourg, France
Chronic Limb-Threatening Ischemia
High-frequency SCS in Treatment of Chronic Limb-Threatening Ischemia
The study of high-frequency spinal cord stimulation (SCS) efficacy in the treatment of chronic limb-threatening ischemia (CLTI)
- Trial name
- HEAL-SCS (NCT05322798)
- Testing
- High-frequency SCS, Low-frequency SCS
- Where
- Russia
- Volunteers
- 25 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Peripheral Arterial Disease
Locomotion and Global Positioning System in Arterial Disease
The maximal walking distance (MWD) performed on treadmill (TT) remains the gold standard in estimating the walking capacity of patients suffering from peripheral arterial disease (PAD) with intermittent claudication, although…
- Trial name
- Starter-GPS (NCT00485147)
- Testing
- Recording of GPS during a free walking in a public park
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Critical Limb Ischemia
Peri-operative Foot CT Perfusion in CLI Patients
To investigate the clinical value of quantitative analysis of peri-operative foot supply through CT perfusion in patients with critical limb ischemia
- Trial name
- POP-CLI (NCT05575778)
- Testing
- computed tomographic perfusion
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Fudan University
Raynaud's Disease, Raynaud's Disease Secondary to Scleroderma
A Study of a Topical Form of Nitroglycerin and Placebo in the Treatment and Prevention of Raynaud's Phenomenon
The purpose of this research study is to test the safety, tolerability, and effectiveness of Topical AmphiMatrix with Nitroglycerin (MQX0503) to relieve Raynaud's symptoms and increase blood flow to the fingers.
- Conditions
- Raynaud's Disease, Raynaud's Disease Secondary to Scleroderma, Raynaud's Disease Secondary to Other Autoimmune Disease
- Trial name
- NCT00577304
- Testing
- Nitroglycerin, Topical AmphiMatrix
- Where
- 17 sites in United States
- Volunteers
- 200 people
- Sponsor
- MediQuest Therapeutics
Peripheral Arterial Disease
Effect of a Hybrid Rehabilitation Program on Walking, Quality of Life & Cardiovascular Risk in People With PAD
Peripheral arterial disease (PAD), a disabling condition, affects 800,000 Canadians. People with PAD suffer from poor quality of life due to leg pain, which makes walking difficult. They also have a high risk of heart disease.
- Trial name
- HY-PAD (NCT03649204)
- Testing
- HY-PAD
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Peripheral Arterial Disease
Exercise on Expression of Heat Shock Protein 70 in Arterial Risk
Introduction: Atherosclerotic Peripheral Arterial Disease (PAD) is the leading cause of mortality in the western world. To maintain homeostasis of the vessel wall, vascular cells produce a high level of heat shock proteins (HSP)…
- Trial name
- HSP70 (NCT04743128)
- Testing
- Exercise
- Where
- Mexico
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad Popular Autónoma del Estado de Puebla
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