Clinical trials: Peripheral Vascular Disease (PVD)
Peripheral Arterial Disease
Remedy, Biodegradable Peripheral Stent Registry
This is a prospective multicenter registry to evaluate safety and performance of the REMEDY, biodegradable peripheral stent for the treatment of occluded or stenotic superficial femoral arteries.
- Trial name
- NCT01420120
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- be Medical
Peripheral Artery Disease
Clinical Outcomes of Three Different Percutaneous Revascularization Strategies for the Treatment of Lifestyle Limiting Claudication: A Retrospective Analysis
To determine the effect of three different percutaneous revascularization strategies (Balloon Cryoplasty vs. Stent Placement vs. Atherectomy) in the treatment of lifestyle limiting lower extremity claudication
- Trial name
- FIX-IT Retro (NCT00512720)
- Where
- United States
- Volunteers
- 355 people
- Sponsor
- Corewell Health West
Peripheral Arterial Disease
Circulating Anti-Beta2-glycoprotein Antibodies and Endothelial Dysfunction
Circulating anti-beta2-glycoprotein antibodies have been associated with coronary artery disease and peripheral arterial disease.
- Trial name
- NCT01822990
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Getafe
Diabetic Neuropathy
VEGF Gene Transfer for Diabetic Neuropathy
This gene therapy study is being conducted to evaluate intramuscular gene transfer using VEGF (Vascular Endothelial Growth Factor) in patients with diabetic neuropathy in the legs.
- Trial name
- NCT00056290
- Testing
- VEGF
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Losordo, Douglas, M.D.
Intermittent Claudication, Vascular Diseases
Secondary Prevention and Application-based Lifestyle Support for Patients With Intermittent Claudication
A randomized controlled pilot trial will be used to test Lifepod®PAD as secondary prevention support system. Approximately 60 patients with intermittent claudication at the Department of vascular diseases at Skåne University…
- Trial name
- PRESIC (NCT04390282)
- Testing
- Application-based support system
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Malmö University
COVID, Critical Limb Ischemia
The Impact of COVID-19 Pandemic on Critical Limb Threatening Ischemia and Emergency Vascular Practice
This is a retrospective analytical study conducted at Vascular and Endovascular surgery Department, Mansoura University Hospital, including all patients admitted at the two periods first six months of 2019 and 2020.To demonstrate…
- Trial name
- NCT04452682
- Testing
- COVID 19 impact
- Where
- Egypt
- Volunteers
- 998 people
- Sponsor
- Mansoura University
Peripheral Arterial Disease
Multi-center Study for Stent Graft System for Peripheral Artery
The utility of GP1101 will be evaluated relative to that of surgical bypass in the treatment of Femoral/Popliteal Arterial Symptomatic Peripheral Arterial Disease.
- Trial name
- VJH11-01 (NCT01575808)
- Testing
- GP1101
- Where
- 15 sites in Japan
- Volunteers
- 133 people
- Sponsor
- W.L.Gore & Associates
Transtibial Amputation, Peripheral Artery Disease
Optimizing Gait Rehabilitation for Veterans With Non-traumatic Lower Limb Amputation
The population of older Veterans with non-traumatic lower limb amputation is growing. Following lower limb amputation, asymmetrical movements persist during walking and likely contribute to disabling sequelae including secondary…
- Conditions
- Transtibial Amputation, Peripheral Artery Disease, Diabetes Mellitus
- Trial name
- GEM (NCT03995238)
- Testing
- Error-augmentation gait training, Error-correction gait training, Supervised walking
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- VA Office of Research and Development
Raynaud's Phenomenon, Systemic Sclerosis
The Effect of Physical Therapy on Raynaud's Phenomenon Secondary to Systemic Sclerosis
The effect of deep oscillation and biofeedback on Raynaud's phenomenon secondary to systemic sclerosis (SSc) remains to be determined.
- Trial name
- NCT00946738
- Testing
- Biofeedback, Deep oscillation
- Where
- Germany
- Volunteers
- 28 people
- Sponsor
- Charite University, Berlin, Germany
Peripheral Arterial Disease
Efficiency, Safety and Portability of Neovasculgen
In 2010, we completed a phase 1 to 2a clinical trial of pCMV-vegf165 in patients with chronic lower limb ischemia (stage 2a to 3 according to Fontaine classification modified by A. V.
- Trial name
- Neovasculgen (NCT03068585)
- Testing
- Neovasculgen (Cambiogeneplasmid)
- Where
- 3 sites in Russia
- Volunteers
- 100 people
- Sponsor
- Artgen Biotech
Coronary Artery Disease, Hypertension
Acute Probiotic Supplementation and Endothelial Function
One in every two deaths in the United States is caused by cardiovascular disease. Despite strong mechanistic links established between a diet rich in lipids and the pathogenesis of cardiovascular disease, therapeutic advances…
- Conditions
- Coronary Artery Disease, Hypertension, Hyperlipidemias, Peripheral Vascular Diseases
- Trial name
- NCT04364074
- Testing
- Goodbelly
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Medical College of Wisconsin
Chronic Limb-Threatening Ischemia, Peripheral Arterial Disease
Structured Educational Program vs Standard Care in Pre-surgical Critical Limb Ischemia Patients
Critical limb ischemia (CLI) is a severe condition where poor blood flow to the legs causes pain, non-healing wounds, and may require amputation. It affects 10% of people over 40, rising to 20% in those over 70.
- Conditions
- Chronic Limb-Threatening Ischemia, Peripheral Arterial Disease, Health Education
- Trial name
- NCT07201168
- Testing
- Structured Multimodal Educational Program for Critical Limb Ischemia, Standard medical care
- Where
- Kazakhstan
- Volunteers
- 184 people
- Sponsor
- Tulip Medicine
Peripheral Arterial Disease
LineMatrix® Biological Vascular Graft for Infra-renal Arterial Bypass or Replacement
Single center, single arm study to evaluate the Safety and Efficacy of LineMatrix® Biological Vascular Graft for Infra-renal Arterial Bypass or Replacement
- Trial name
- NCT07733076
- Testing
- LineMatrix® Biological Vascular Graft
- Volunteers
- 15 people
- Sponsor
- Shanghai Zhongshan Hospital
Peripheral Arterial Disease, Diabetic Foot Ulcer
Study of PDA-002 in Subjects With Peripheral Arterial Disease and Diabetic Foot Ulcers
This Phase 1, multicenter, open-label, dose-escalation study evaluated the safety and tolerability of intramuscular administration of PDA-002 (human placenta-derived cells) in subjects with peripheral arterial disease (PAD) and…
- Trial name
- NCT01859117
- Testing
- PDA-002
- Where
- 12 sites in United States
- Volunteers
- 15 people
- Sponsor
- Celularity Incorporated
Raynaud's Phenomenon Secondary to Systemic Sclerosis
Effects of Selexipag in Adults With Raynaud's Phenomenon Secondary to Systemic Sclerosis
The primary objective of the study is to determine the activity of selexipag on Raynaud attack frequency in subjects with Raynaud's Phenomenon (RP) secondary to Systemic Sclerosis (SSc).
- Trial name
- NCT02260557
- Testing
- Selexipag
- Where
- 16 sites in France, Germany and 1 more
- Volunteers
- 74 people
- Sponsor
- Actelion
Peripheral Arterial Disease
The Value of Supervised Exercise Therapy After Invasive Treatment of Peripheral Arterial Disease
The objective of this study is to investigate what the value is of SET after a radiological or surgical intervention for peripheral arterial disease in the aorto-iliacal, femoro-popliteal and crural segments in comparison with a…
- Trial name
- NETP-extra (NCT00497445)
- Testing
- angioplasty / surgery, Angioplasty / surgery and exercise therapy
- Where
- Netherlands
- Volunteers
- 86 people
- Sponsor
- Atrium Medical Center
Peripheral Artery Disease, Peripheral Artery Occlusion
Peripheral Artery Disease and Sepsis Outcomes
The peripheral artery disease (PAD) prevalence is high in the elderly, the diabetic patients, and the patients receiving hemodialysis.
- Conditions
- Peripheral Artery Disease, Peripheral Artery Occlusion, Sepsis, Diagnosis
- Trial name
- NCT03372330
- Testing
- Standard care for sepsis and PAD, Standard care for sepsis
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Postphlebitic Syndrome, Post-Thrombotic Syndrome
The 36-month Extension to Follow up Sub Study
The purpose of this study is to evaluate leg health for one additional year in patients with symptomatic proximal deep venous thrombosis who did not already develop Post-Thrombotic Syndrome (PTS) during the 2 years of follow up…
- Conditions
- Postphlebitic Syndrome, Post-Thrombotic Syndrome, Deep Vein Thrombosis
- Trial name
- NCT01615692
- Where
- 20 sites in Canada
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Peripheral Artery Disease
Evaluation of Imaging of Peripheral Arteries by Optical Coherence Tomography and Intravascular Ultrasound Imaging
A non inferiority trial to determine the capability of optical coherence tomography (OCT) imaging to show vessel morphology in comparison to imaging provided by intravascular ultrasound imaging (IVUS).
- Trial name
- SCAN (NCT03480685)
- Testing
- IVUS and OCT Imaging
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Avinger, Inc.
Intermittent Claudication
Person-centered Follow up and Health Promotion Program After Revascularization for Intermittent Claudication
The overall aim of the study is to evaluate a nurse-led intervention (person-centered follow up and health promotion) program in comparison to standard follow up for patients treated with surgical or endovascular…
- Trial name
- FASTIC (NCT03283358)
- Testing
- Person-centered follow up
- Where
- 2 sites in Sweden
- Volunteers
- 213 people
- Sponsor
- Karolinska Institutet
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