Clinical trials: Peritoneal Dialysis (PD)
Chronic Kidney Failure
Icodextrin Study to Test Short-Term Safety, Tolerability and Preliminary Efficacy of Sodium-Free Solution in PD Patients
Patients with kidney failure rely on dialysis for sodium and fluid removal. The importance of a sodium and fluid balance in patients with kidney disease is very important.
- Trial name
- NCT05185999
- Testing
- Icodextrin/Dextrose
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Renal Failure, Chronic Kidney Disease
Clinical Performance of the Therapy Option FlexPoint of the PD Cycler Sleep•Safe Harmony
Analysis and comparison of treatments with and without the FlexPoint technology (flexible volume and dwell time management) of the PD cycler sleep•safe harmony
- Trial name
- FlexPoint (NCT06390592)
- Testing
- PD cycler
- Volunteers
- 24 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Peritoneal Dialysis, Hypervolemia
Lung Ultrasound in PD Patients
Although many alternative methods are present, maintaining ideal volume status in peritoneal dialysis (PD) patients still rely on clinical evaluation due to lack of an evidence based method.
- Conditions
- Peritoneal Dialysis, Hypervolemia, VEGF Overexpression
- Trial name
- LUSiPD (NCT03801044)
- Testing
- NT-BNP, VEGF, Echocardiography, Chest Radiography
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Kidney Disease, Chronic, Peritoneal Dialysis Catheter-Associated Peritonitis
Targeted Education ApproaCH to Improve Peritoneal Dialysis Outcomes Trial
For many patients peritoneal dialysis (PD) is the preferred form of dialysis to treat kidney disease as it provides greater flexibility and the ability to dialyse at home.
- Conditions
- Kidney Disease, Chronic, Peritoneal Dialysis Catheter-Associated Peritonitis, Peritoneal Dialysis Catheter Exit Site Infection, Peritoneal Dialysis Catheter Tunnel Infection
- Trial name
- TEACH-PD (NCT03816111)
- Testing
- TEACH-PD Training Curriculum, Current standard PD training
- Where
- 48 sites in Australia, New Zealand
- Volunteers
- 1,462 people
- Sponsor
- The University of Queensland
Renal Failure, Chronic Kidney Diseases
Influence of Variable Inflow Volume, Dwell Duration and Glucose Concentration on Ultrafiltration Volume in APD Patients
The purpose of the current investigation is to provide proof of concept for a future approach to improve UF prediction accuracy.
- Trial name
- pPD (NCT06443021)
- Testing
- PD cycler
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Chronic Kidney Disease, Peritoneal Dialysis
Effect of Protein-Restricted Diet on Nitrogen Balance and Residual Renal Function in Peritoneal Dialysis (PD) Patients
Current therapy recommendations suggest a low protein diet to preserve residual renal function (RRF) before the start of dialysis, but a higher protein intake during dialysis to prevent protein-energy wasting (PEW).
- Trial name
- NCT00633646
- Testing
- diets contained different levels of protein
- Volunteers
- 94 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Peritonitis, Kidney Failure
IV Antibiotics With Lavage for Severe PD Peritonitis
This is a randomized controlled trial to evaluate whether a switch to intravenous antibiotics with adjunctive lavage can improve the outcome of severe peritoneal dialysis related peritonitis.
- Trial name
- NCT02926846
- Testing
- Intravenous vancomycin & gentamicin with adjunctive lavage, Intraperitoneal vancomycin & gentamicin
- Where
- Hong Kong
- Volunteers
- 46 people
- Sponsor
- Alice Ho Miu Ling Nethersole Hospital
Heart Failure, Chronic Kidney Disease
PD-HF: A Trial of Peritoneal Dialysis in Patients With Severe Heart Failure and Chronic Kidney Disease
This trial is to establish whether ultrafiltration by peritoneal dialysis is a clinically effective treatment for patients with severe heart failure and moderate chronic kidney disease, thus improving quality of life and symptoms.
- Trial name
- PD-HF (NCT02708407)
- Testing
- Peritoneal Dialysis
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- University of Nottingham
End Stage Renal Disease on Dialysis, Peritoneal Dialysis
China Q Cohort Study
The burden of end-stage kidney disease (ESKD) is increasing worldwide. Although kidney transplantation is the most cost-effective renal replacement therapy, dialysis is still the main way to treat ESRD patients due to the limited…
- Conditions
- End Stage Renal Disease on Dialysis, Peritoneal Dialysis, Hemodialysis
- Trial name
- NCT04197674
- Testing
- Dialysis modality
- Where
- China
- Volunteers
- 903 people
- Sponsor
- Sun Yat-sen University
Chronic Kidney Disease (CKD), Secondary Hyperparathyroidism (SHPT)
A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Paricalcitol For Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Participants With Stage 5 Chronic Kidney Disease (CKD)
The main objective of this study is to evaluate the safety, efficacy and pharmacokinetics of paricalcitol oral solution in pediatric participants of ages 0 to 9 years with SHPT associated with stage 5 CKD receiving Peritoneal…
- Trial name
- NCT04064827
- Testing
- Paricalcitol
- Where
- 15 sites in United States, Puerto Rico
- Volunteers
- 2 people
- Sponsor
- AbbVie
ESRD
The Study of Efficacy and Safety of Automated PD in Urgent Start Dialysis
This is a multi-center, controlled clinical trial study. The purpose of this study is to examine the efficacy and safety of automated peritoneal dialysis as compared with intermittent haemodialysis for ESRD patients with…
- Trial name
- URG-APD (NCT03754361)
- Testing
- automated peritoneal dialysis, IHD
- Where
- 5 sites in China
- Volunteers
- 34 people
- Sponsor
- Peking Union Medical College Hospital
End-stage Kidney Disease
Percutaneous Peritoneal Dialysis Catheter Insertion (PREDICT)
Peritoneal dialysis (PD) is the most frequent modality of home dialysis for patients with kidney failure. Most PD catheters are placed using a laparoscopic technique.
- Trial name
- PREDICT (NCT06065982)
- Testing
- Questionnaires
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 500 people
- Sponsor
- Universitair Ziekenhuis Brussel
Fluid Status, Peritoneal Dialysis
Bioimpedance as a Tool for Fluid Management in Peritoneal Dialysis (PD) Patients
Hypothesis: The investigators hypothesize that regular monitoring of BIA adds value to the management of fluid status in PD patients Objectives of the study: The objective is to show that in patients where the additional…
- Trial name
- NCT00801112
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University Hospital of North Staffordshire
End-Stage Renal Disease
Dietary Adherence Enhancement in Peritoneal Dialysis: BalanceWise-PD
This randomized study will pilot test an intervention, based on self-efficacy theory and involving personal digital assistant (PDA)-based dietary self-monitoring, to improve adherence to the peritoneal dialysis dietary regimen.
- Trial name
- BalanceWise-PD (NCT00447317)
- Testing
- BalanceWise-PD, Attention control
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pittsburgh
Chronic Kidney Disease (Stages 4 and 5), Peritoneal Dialysis (PD)
Probiotic and Prebiotic Supplementation in Peritoneal Dialysis Patients
The goal of this clinical trial is to learn if synbiotics work to lower inflammation in adults with chronic kidney disease who are on peritoneal dialysis.
- Trial name
- NCT07694791
- Testing
- Synbiotic
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Anemia of End Stage Renal Disease
TARGTEPO Treatment for Anemia in End Stage Renal Disease (ESRD) Patients Undergoing Peritoneal Dialysis (PD)
The objectives of this study are to assess safety and to evaluate the biologic activity of TARGTEPO treatment in Peritoneal Dialysis patients
- Trial name
- NCT02378662
- Testing
- MDGN201 TARGTEPO
- Where
- 2 sites in Israel
- Volunteers
- 2 people
- Sponsor
- Aevi Genomic Medicine, LLC, a Cerecor company
CKD (Chronic Kidney Disease) Stage 5D, Peritoneal Dialysis (PD)
The Effect of Exercise on Blood Pressure Variability on Peritoneal Dialysis Patients
In China, the chronic kidney disease (CKD) incidence rate is as high as 10.8%. Renal replacement therapy plays an critical role in the later stage of CKD and becomes mandatory, as end-stage renal disease (ESRD) is unavoidable in…
- Trial name
- NCT07098923
- Testing
- combination of aerobic and resistance exercise
- Where
- China
- Volunteers
- 55 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Disorders Associated With Peritoneal Dialysis
Effects of Aceis on Peritoneal Protein Loss and Solute Transport in pd Patients
The objective of this study was to examine the effects of angiotensin converting enzyme inhibitors on peritoneal membrane transport, peritoneal protein loss, and proteinuria in peritoneal dialysis patients.
- Trial name
- NCT01575652
- Testing
- Group using angiotensin converting enzyme inhibitor, Group not using angiotensin converting enzyme inhibitor
- Volunteers
- 43 people
- Sponsor
- Turkish Nephrology Association
End Stage Renal Disease
Safety and Efficacy of the Addition of Alanyl-Glutamine-Dipeptide to Dialysis Solution in Peritoneal Dialysis
Peritoneal dialysis (PD) is a cost effective and safe form of renal replacement therapy in patients suffering from end stage renal disease.
- Trial name
- NCT01353638
- Testing
- Dipeptiven (Alanyl-glutamine-dipeptide)
- Where
- Austria
- Volunteers
- 25 people
- Sponsor
- Christoph Aufricht
Anemia of End Stage Renal Disease
TARGTEPO Treatment for Anemia in PD US Trial
The objectives of this study are to assess safety and to evaluate the biologic activity of TARGTEPO treatment in Peritoneal Dialysis patients
- Trial name
- NCT02468414
- Testing
- MDGN201 TARGTEPO
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Aevi Genomic Medicine, LLC, a Cerecor company