Clinical trials: Peritoneal Dialysis Complication
ESRD, Peritoneal Dialysis
Effect of N-Acetylcysteine on Peritoneal Membrane Function in Chronic Peritoneal Dialysis Patients
The aim of our study is to investigate the effect of N-acetylcysteine on peritoneal small solute clearance and removal of salt and water in prevalent CAPD patients.
- Trial name
- NCT00421785
- Testing
- Oral N-Acetylcysteine 1200 mg x 2/day for 4 weeks.
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Assaf-Harofeh Medical Center
Peritoneal Dialysis, Chronic Kidney Disease
Study of Safety and Efficacy of Renagel® Compared With Calcium Acetate in Patients With Peritoneal Dialysis
The purpose of this study is to demonstrate that sevelamer hydrochloride is non-inferior to calcium acetate for the treatment of hyperphosphataemia in patients receiving peritoneal dialysis.
- Trial name
- NCT00196755
- Testing
- Sevelamer Hydrochloride (Renagel®), Calcium acetate (PhosLo® )
- Where
- 17 sites in Belgium, Denmark and 5 more
- Volunteers
- 138 people
- Sponsor
- Genzyme, a Sanofi Company
Renal Failure, Chronic Kidney Diseases
Influence of Variable Inflow Volume, Dwell Duration and Glucose Concentration on Ultrafiltration Volume in APD Patients
The purpose of the current investigation is to provide proof of concept for a future approach to improve UF prediction accuracy.
- Trial name
- pPD (NCT06443021)
- Testing
- PD cycler
- Sponsor
- Fresenius Medical Care Deutschland GmbH
End Stage Renal Disease (ESRD)
Evaluate the Efficacy and Safety of Amino Acid (15) Peritoneal Dialysis Solution in Peritoneal Dialysis Patients with Malnutrition.
This is a multicenter, randomized, parallel controlled Phase IV clinical study to evaluate the safety and efficacy of amino acid (15) peritoneal dialysis solution in patients undergoing peritoneal dialysis with malnutrition in…
- Trial name
- NCT06597201
- Testing
- amino acid (15) peritoneal dialysis solution, glucose peritoneal dialysis solution
- Where
- 21 sites in China
- Volunteers
- 400 people
- Sponsor
- Chengdu Qingshan Likang Pharmaceutical Co., Ltd
Chronic Kidney Disease, Anemia
The Effect on Vascular Reactivity Using the Erythropoeitin Alpha on Incident Peritoneal Dialysis Patients
This is a prospective observational study on incident peritoneal dialysis patients on the effect of hemoglobin level and vascular reactivity using the generic erythropoietin alpha.
- Conditions
- Chronic Kidney Disease, Anemia, Complication of Peritoneal Dialysis
- Trial name
- NCT03286712
- Testing
- Renogen
- Where
- Philippines
- Volunteers
- 30 people
- Sponsor
- National Kidney and Transplant Institute, Philippines
Chronic Kidney Disease (CKD) Stage 5, Peritoneal Dialysis Access
PD Catheter Survival: Modified Percutaneous vs Moncrief-Popovich
Peritoneal dialysis (PD) catheter placement technique may affect catheter survival, functionality and infection risk. The Moncrief-Popovich (subcutaneous burying or embedding) technique was developed to reduce exit-site/tunnel…
- Trial name
- NCT07465445
- Testing
- Embedded Peritoneal catheter placement, Modified Percutaneous PD catheter placement
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital Civil de Guadalajara
End-stage Renal Disease
Transfer and Ultrafiltration In Peritoneal Dialysis
The aim of this study is to demonstrate the efficiency of an adapted and "alternate" peritoneal dialysis scheme in terms of sodium extraction and purification compared to an adapted conventional peritoneal dialysis scheme.
- Trial name
- TULIPE (NCT02474719)
- Testing
- comparison of two regimens in peritoneal dialysis
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Continuous Ambulatory Peritoneal Dialysis, End Stage Renal Disease
Ertapenem Pharmacokinetics in Patients in Continuous Ambulatory Peritoneal Dialysis
The objective of this study is to characterize the pharmacokinetic profile of ertapenem during continuous ambulatory peritoneal dialysis (CAPD).
- Trial name
- NCT00939952
- Testing
- ertapenem
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Albany College of Pharmacy and Health Sciences
Dialysis, Anemia
Study of Roxadustat (FG-4592) to Correct Anemia in Newly Initiated Dialysis Participants Not on Erythropoiesis-Stimulating Agent Treatment
The purpose of this study is to evaluate efficacy and safety of roxadustat in the correction of anemia in participants with end-stage renal disease who recently started dialysis.
- Trial name
- NCT01414075
- Testing
- Roxadustat, Oral Iron, IV Iron
- Where
- 7 sites in United States, Hong Kong and 2 more
- Volunteers
- 60 people
- Sponsor
- Kyntra Bio
Cognitive Impairment, Chronic Kidney Diseases
The Kidney and The Brain Study - Assessment of Cognitive Impairment in Advanced CKD
Patients with failed kidneys need Renal Replacement Therapy (RRT) to remove fluid and toxins from the body. The 3 types of RRT are kidney transplant or removal of waste by dialysis, either via the blood (haemodialysis) or via the…
- Conditions
- Cognitive Impairment, Chronic Kidney Diseases, End Stage Renal Disease, Dementia
- Trial name
- NCT03382444
- Testing
- Cognitive Assessment, Depression and Quality of Life Assessment
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- Natalie Garratt
ESRD, Peritoneal Dialysis
Evaluate Serious Illness Treatment Preferences and Outcomes in the Patients Receiving Peritoneal Dialysis
The goal of this clinical research study is to study the cardiopulmonary resuscitation (CPR) preferences of patients receiving peritoneal dialysis and how these preferences are associated with their responses to questions about…
- Trial name
- NCT05193474
- Testing
- integrated palliative care
- Volunteers
- 500 people
- Sponsor
- National Taiwan University Hospital
End Stage Kidney Disease (ESKD)
Acupuncture for Symptom Burden and Quality of Life in Patients With End-Stage Kidney Disease
Patients with end-stage kidney disease (ESKD) undergoing hemodialysis or peritoneal dialysis experience a high burden of symptoms, including fatigue, pain, pruritus, muscle cramps, and sleep disturbances, which substantially…
- Trial name
- Acup-ESKD (NCT07887607)
- Testing
- Acupuncture
- Where
- Greece
- Volunteers
- 160 people
- Sponsor
- University General Hospital of Heraklion
End Stage Renal Disease, Peritoneal Dialysis
Chlorhexidine Gluconate Versus Mupirocin Ointment in the Prevention of Peritoneal Dialysis-Related Infection
This pilot study aims to evaluate effectiveness, safety, and cost-utility of chlorhexidine gluconate (CHG)-soaked cloths compares to mupirocin ointment and exit site usual care (normal saline) with aseptic technique in prevention…
- Trial name
- COSMO-PD (NCT02547103)
- Testing
- Chlorhexidine gluconate-soaked cloths, Normal saline, mupirocin ointment
- Where
- Thailand
- Volunteers
- 354 people
- Sponsor
- Chiang Mai University
Peritoneal Infection
Intervention to Reduce Infectious Complications of Peritoneal Dialysis
Peritonitis is a common and serious complication of peritoneal dialysis (PD) and is one of the main causes of peritoneal dialysis technique failure and long-term hemodialysis conversion.
- Trial name
- NCT06536673
- Testing
- Intervention to reduce infectious complications of peritoneal dialysis, Data collection from the patient's clinical history
- Volunteers
- 80 people
- Sponsor
- Universitat de Lleida
Acute Kidney Injury
Automated Peritoneal Dialysis Versus Intermittent Hemodialysis in Acute Kidney Injury
This is a multi-center randomized clinical trial study. The purpose of this study is to examine safety, feasibility and efficacy of automated peritoneal dialysis as compared with intermittent hemodialysis for AKI patients with…
- Trial name
- SAFE-APD (NCT03598387)
- Testing
- Automated peritoneal dialysis, Intermittent hemodialysis
- Where
- 5 sites in China
- Volunteers
- 100 people
- Sponsor
- Limeng Chen
Chronic Kidney Disease, Peritoneal Dialysis
Evaluation of the Peritoneal Dialysis Program in a Hospital in Chinandega, Nicaragua.
The purpose of this study is to develop recommendations to assist in improving the current peritoneal dialysis (PD) program in a Hospital in Chinandega, Nicaragua.
- Trial name
- NCT02270229
- Volunteers
- 60 people
- Sponsor
- La Isla Foundation
End Stage Renal Disease
Use of a Bimodal Solution for Peritoneal Dialysis
Peritoneal dialysis (PD) is the method of renal replacement therapy used by close to 200,000 end stage renal disease patients worldwide to help replace the functions that are no longer performed by their kidneys.
- Trial name
- NCT01242904
- Testing
- bimodal solution, icodextrin
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
End Stage Renal Disease, Peritoneal Dialysis-associated Peritonitis
A Prospective Clinical Study to Assess the Clinical Utility of Turbidity in Patients Using In-Home Peritoneal Dialysis
This study aims to determine if the CloudCath device can detect infections related to peritoneal dialysis (peritonitis) as fast or faster than the current standard methods used by patients and doctors to detect such infections.
- Conditions
- End Stage Renal Disease, Peritoneal Dialysis-associated Peritonitis, Peritonitis
- Trial name
- ACT (NCT05285436)
- Testing
- CloudCath System
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- CloudCath
Chronic Kidney Disease Stage 5
Quality of Life and Depression in Dialysis Patients
The aim of this study is to evaluate quality of life (QOL) and depression in peritoneal dialysis patients compare to hemodialysis patients and assess hydration effect on QOL and depression over time.
- Trial name
- QOLD (NCT01668628)
- Where
- South Korea
- Volunteers
- 1,068 people
- Sponsor
- Fresenius Medical Care Korea
Chronic Kidney Disease
Diurnal Variation of Uremic Solutes in Peritoneal Dialysis
Study on the daytime variation of uremic retention solutes and markers of bone-mineral metabolism in patients with end-stage kidney disease treated with peritoneal dialysis
- Trial name
- NCT01093456
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven