Clinical trials: Permanent Molars
Restorative Dental Treatment by Buccal Infiltration Anaesthesia
Clinical Evaluation of Anaesthetic Efficacy of 4% Articaine Buccal Infiltration Versus Inferior Alveolar Nerve Block
Clinical evaluation of anaesthetic efficacy of 4% articaine buccal infiltration versus inferior alveolar nerve block during restorative dental treatment in mandibular first permanent molars
- Trial name
- NCT06353815
- Testing
- 4% articaine infiltration
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis, Pulpotomy of Permanent Molars
Effectiveness of Pulpotomy in Symptomatic Permanent Teeth With Deep Caries Lesions
Preservation of pulp tissue would allow it to continue to exert its defensive and physiological functions and more tooth tissue would be preserved, leading to less weakening of the tooth.
- Trial name
- NCT06918639
- Testing
- Pulpotomy
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universidad Rey Juan Carlos
Dental Caries in Children
Correlation Between Dental Caries Prevalence in Primary Teeth and First Permanent Moilar of Children in Mixed Dentition Stage
to find the clinical relation between caries experience in primary teeth and first permanent molar in mixed dentition stage using def index for primary teeth , DMF index for first permanent molars and to find the clinical…
- Trial name
- NCT04618731
- Testing
- caries prevalence def ,DMF
- Volunteers
- 1,000 people
- Sponsor
- Cairo University
Glass Ionomer Cement, Cost-effectiveness
Effectiveness and Economic Evaluation of Glass Ionomer Material Using as Dental Sealant
Eruption of the first permanent molar is the earliest in our oral cavity, leading to a high occurrence of dental caries in its pits and fissures.
- Conditions
- Glass Ionomer Cement, Cost-effectiveness, Pit and Fissure Caries (Disorder)
- Trial name
- NCT03034837
- Testing
- resin sealant, ART sealant
- Where
- 2 sites in China
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Zhengzhou University
Dental Caries Extending to Pulp, Pulp Disease, Dental
Assessment of Vital Pulp Therapy in Permanent Molars
The purpose of this study is to evaluate the long term clinical performance of vital pulp therapy of young permanent teeth with irreversible pulpitis
- Trial name
- NCT03410134
- Testing
- NeoMTA
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Irreversible Pulpitis, Apical Periodontitis
Success of Pulpotomy in Molars With Pulpitis With Periodontitis Detected Using AI and Those Without Periodontitis
Statement of problem: Although performing full pulpotomy in mature permanent molars with irreversible pulpitis showed success rates comparable to RCT, there is a growing need for further studies in order to determine the…
- Conditions
- Irreversible Pulpitis, Apical Periodontitis, Pulpitis
- Trial name
- NCT06767371
- Testing
- Patients with mature permanent molars diagnosed with severe pulpitis with apical periodontitis to be treated with full pulpotomy., Patients with mature permanent molars diagnosed with moderate pulpitis without apical periodontitis to be treated with full pulpotomy., Teeth with irreversible pulpitis
- Where
- Egypt
- Volunteers
- 57 people
- Sponsor
- Misr International University
Cost Effectiveness
Clinical and Cost-effectiveness of Fluoride Varnish Versus Resin Based Sealant (Part 2)
The aim of the present study is determine the cost-effectiveness, clinical- effectiveness, acceptability and adverse effect of resin sealants versus the fluoride varnish for the prevention of dental caries on newly erupted…
- Trial name
- NCT04793256
- Testing
- Fluoride varnish (3M Clinpro White Varnish 5% sodium fluoride)., Resin based fissure sealant (3M Clinpro Sealant)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Cairo University
Molar Incisor Hypomineralization
Effects of Different Remineralization Agents on Molar Incisor Hypomineralization Defects: a Randomized Clinical Study
The aim of this study was to present a comparative evaluation of the long-term efficacy of fluoride varnish( Flúor protector), Clinpro™ White Varnish and pastes containing CPP-ACP in the remineralization of creamy-white and…
- Trial name
- NCT06362681
- Testing
- Fluoride
- Where
- Mexico
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Caries, Dental
Clinical Evaluation of Bioactive Resin Sealants vs Conventional Sealants in Permanent Molars
This study will be conducted to evaluate the performance; in terms of retention and caries inhibition; of the newly introduced bioactive resin based pits and fissure sealant versus conventional resin based pits and fissure…
- Trial name
- NCT03779893
- Testing
- BioCoat® by Premier®., 3M™ Clinpro™ Sealant.
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulp Exposure, Dental
Simvastatin Versus MTA in Pulpotomy of Immature Permanent Molars
the study will be done to evaluate the clinical and digital radiographic success of simvastatin versus MTA in pulpotomy of immature permanent molars
- Trial name
- NCT05878158
- Testing
- Simvastatin
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- Ahmad Elheeny
Prevalence of Curvatures in Root Canals, Direction of Curvatures in Root Canals
Assessment of Root Canal Curvatures of the Permanent Mandibular First and Second Molars in a Sample of Egyptian Population Using CBCT
A cross-sectional study to assess variations in root canal curvatures of the Permanent Mandibular First and Second Molars in a Sample of Egyptian Population using cone beam computed tomography through retrospective data analysis
- Conditions
- Prevalence of Curvatures in Root Canals, Direction of Curvatures in Root Canals, Severity of Curvatures in Root Canals
- Trial name
- NCT04555070
- Volunteers
- 272 people
- Sponsor
- Cairo University
Carious Exposure, Human Permanent First and Second Molars
RCT of Pulp Capping Over Carious Exposure in Adults
This multicentre study was a randomized, controlled, parallel, patient-blinded, two-arm superiority trial with a 1:1 allocation ratio that followed the CONSORT guidelines.The aim of this study was to investigate whether MTA is…
- Conditions
- Carious Exposure, Human Permanent First and Second Molars, Mature Teeth, Proximal Caries
- Trial name
- NCT01224925
- Testing
- Direct pulp capping with Dycal, Direct pulp capping
- Where
- 4 sites in Lithuania, Norway
- Volunteers
- 80 people
- Sponsor
- University of Tromso
Irreversible Pulpitis
PRF Pulpotomy Using Different Bioceramic Materials in Permanent Molars
this study aimed to compare the clinical and radiographic outcomes of full pulpotmy after application of Biodentine, or MTA, or Portland cement above PRF membrane In permanent molars with irreversible pulpitis
- Trial name
- NCT04784949
- Testing
- portland cement, Mineral trioxide aggregate, Biodentine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Fayoum University
Pulpitis - Irreversible
TheraCal Materials Versus MTA in Full Pulpotomy
The goal of this randomized clinical trial is to compare the clinical performance of three pulp capping materials used in full pulpotomy procedures in mature mandibular molars with symptomatic irreversible pulpitis.
- Trial name
- NCT07660549
- Testing
- Mineral Trioxide Aggregate (MTA), Theracal LC, TheraCal PT
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Cukurova University
Irreversible Pulpitis
Comparing MTA Pulpotomy to Root Canal Treatment in Management of Permanent Molars With Irreversible Pulpitis in Children
Dental caries, highly prevalent amongst children, can cause pulpitis. Coronal pulpotomy provides an easier, cost-effective, conservative and biologically-driven treatment option compared to endodontic treatment in mature…
- Trial name
- NCT06488131
- Testing
- MTA Pulpotomy, Root Canal Treatment
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Molar Incisor Hypomineralisation, Enamel Breakdown
Correlation Between Colour of Defect and Enamel Breakdown in First Permanent Molars With Molar Incisor Hypomineralisation (MIH)
Cheese molars (MIH) can be recognized not only by their colour abnormalities but also by the enamel breakdown. Clinical management of those teeth may become challenging by the chronic hypersensitivity, that makes various steps…
- Conditions
- Molar Incisor Hypomineralisation, Enamel Breakdown, Colour of Defect
- Trial name
- MIH (NCT07727200)
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Basel
No Condition, Assessment of Healthy Volunteers
Usefulness of Intraosseous Anesthesia for Permanent Tooth Extraction Under GA in Pediatric Dental Treatment
The investigators are doing a study to see if a new way of giving local anesthesia during dental surgery can help children feel better after having a tooth removed under general anesthesia (when they are fully asleep).
- Trial name
- NCT07108439
- Testing
- Administration of intra-osseous local anesthesia before the extraction of a first permanent molar under general anesthesia
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- University Hospital, Ghent
Necrotic Mandibular Molars, Apical Periodontitis
Impact of Minimally Invasive Endodontic Treatment on the Prognosis of Mandibular Permanent Molars With Necrotic Pulp and Apical Periodontitis
Statement of the problem: The effectiveness of minimally invasive endodontic treatments in managing necrotic pulp with apical periodontitis remains understudied.
- Trial name
- NCT07762248
- Testing
- Root canal treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mohamed Ashraf Abdeen
Molar Incisor Hypomineralization
Zirconia Versus Lithium Di-silicate Overlays for Restoring Hypomineralized Molars Affected With MIH
the study evaluate the clinical outcome of zirconia versus lithium disilicate overlays restorations for restoring vital young permanent first molar teeth affected with moderate form of molar Incisor hypomineralization: randomized…
- Trial name
- NCT05529329
- Testing
- overlay
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Al-Azhar University
Resin Infiltration, Pit and Fissure Sealant
Resin Infiltrate as Pit and Fissure Sealant in Permanent Molars
The aim of this study is to evaluate and compare the clinical effectiveness of ICON resin Infiltration versus conventional sealant and the microleakage and penetration depth of the two sealant materials.
- Conditions
- Resin Infiltration, Pit and Fissure Sealant, Permanent Molars
- Trial name
- NCT06729788
- Testing
- ICON resin infiltration Material group in vivo, Resin-based fissure sealant group in vivo, ICON resin infiltration in vitro
- Where
- Egypt
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Tanta University