Clinical trials: Peroperative Complication
Blood Loss, Surgical
The Efficacy of Carbitocin in Reduction of Blood Loss During Myomectomy
The uterine fibroids are the most common benign tumors found in the female reproductive system. Uterine fibroids commonly cause heavy menstrual periods.
- Trial name
- NCT07721623
- Testing
- Carbetocin
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Alex Ekwueme Federal University Teaching Hospital
Rotator Cuff Tears, Shoulder Arthorscopy Surgery
Arthroscopic Shoulder Surgery With Administration of Intravenous Tranexamic Acid
Purpose: The study aimed to determine whether intravenous administration of tanexamic acid (TXA) before shoulder arthroscopic rotator cuff repair surgery can improve arthroscopy visual clarity.
- Conditions
- Rotator Cuff Tears, Shoulder Arthorscopy Surgery, Surgical Blood Loss, Tranexamic Acid
- Trial name
- NCT04025736
- Testing
- Tranexamic Acid 100Mg/Ml Inj Vil 10Ml, 0.9% Sodium Chloride Injection
- Where
- Taiwan
- Volunteers
- 72 people
- Sponsor
- National Cheng-Kung University Hospital
Hemorrhage, Platelets; Defect
Extended Cold Stored Apheresis Platelets in Cardiac Surgery Patients
This trial is being performed to evaluate the feasibility of the study protocol and to test the efficacy and safety of platelets stored at cold conditions (1-6°C) in 100% plasma for 10-14 days (CSP) in cardiac surgery patients…
- Conditions
- Hemorrhage, Platelets; Defect, Bleeding, Surgical Blood Loss
- Trial name
- CHASE (NCT05220787)
- Testing
- Cold stored platelets in 100% plasma stored for 10-14 days, Room temperature stored platelets in 100% plasma stored for up to 7 days
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Moritz Stolla, MD
Postoperative Complications, Intraoperative Complications
Uterine Transposition: Feasibility Study
This prospective nonrandomized multicenter phase I study, will evaluate the feasibility of performing uterine transposition before chemoradiation for rectal cancer and uterine reimplantation after the treatment.
- Conditions
- Postoperative Complications, Intraoperative Complications, Tissue Damage, Ovarian Failure
- Trial name
- NCT03040921
- Testing
- Uterine transposition.
- Where
- Brazil
- Volunteers
- 9 people
- Sponsor
- Hospital Erasto Gaertner
Pelvic Organ Prolapse, PONV
Effects of Preoperative Dexamethasone Study on QOL After Vaginal Reconstructive Surgery for POP
The investigators hypothesize that preoperative administration of 8 mg IV dexamethasone will benefit patients' perceived quality of recovery after surgery.
- Trial name
- NCT02073734
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- TriHealth Inc.
Chronic Rhinosinusitis (CRS) with and Without Nasal Polyps
Correlation of Preoperative Indices (serum Vit D, Calcium, Phosphorus, FAR, PLR, SII) on Intraoperative Bleeding in CRS
The purpose of this observational study was to examine whether preoperative indicators correlate with intraoperative bleeding to facilitate control of intraoperative bleeding.
- Trial name
- NCT06737198
- Testing
- without interventios.
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Blood Loss, Surgical, Postpartum Hemorrhage
Ideal Time of Oxytocin Infusion During Cesarean Section
This study will evaluate if the timing of oxytocin administration in cesarean deliveries will affect the amount of maternal blood loss.
- Conditions
- Blood Loss, Surgical, Postpartum Hemorrhage, Bleed Pregnancy, Pregnancy Related
- Trial name
- I-TOPICS (NCT03246919)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Loyola University
Chronic Rhinosinusitis (Diagnosis)
The Influence of Blood Pressure Upon the Clarity of Surgical Field in Endonasal Surgery
The work compares the effect of different various values of arterial blood pressure on the clarity of the surgical field in pansinusoperation in patients with chronic rhinosinusitis.
- Trial name
- NCT03815435
- Testing
- Controlled hypotension
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- University Hospital Ostrava
Blood Loss, Surgical
Observational Cohort Study of TachoSil (TC-018-IN)
The purpose of this study is to collect information, after exposure to TachoSil ®, of all thromboembolic events, immunological events and drug interactions leading to thromboembolic events or major bleeding.
- Trial name
- NCT00285623
- Testing
- Fibrinogen (human) + thrombin (human) (TachoSil)
- Where
- Denmark
- Volunteers
- 3,000 people
- Sponsor
- Nycomed
Surgical Blood Loss, Postoperative Blood Loss
Study of Fibrinogen Concentrate (Human) (FCH) to Control Bleeding During Complex Cardiovascular Surgery
The purpose of this study is to demonstrate that Fibrinogen Concentrate (Human)(FCH) can reduce the amount of donor blood products needed during complex cardiovascular surgery, and that it is safe and well tolerated.
- Trial name
- REPLACE (NCT01475669)
- Testing
- Fibrinogen Concentrate (Human) (FCH)
- Where
- 35 sites in Austria, Brazil and 9 more
- Volunteers
- 152 people
- Sponsor
- CSL Behring
Sepsis, Primary Myopathies
Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies
The primary aim of the project is to apply the non-invasive stimulated muscle force assessment system to i) intensive care unit patients and ii) patients with primary myopathy or subclinic myopathy (e.g., Duchenne muscular…
- Trial name
- NCT00735384
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Blood Loss, Surgical, Blood Loss, Postoperative
Comparison Study of Oxytocin Versus Tranexamic Acid and Etamsylaye Versus Placebo(Saline)
Comparison Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate Versus Normal Saline as Pre-operative Administration.
- Trial name
- NCT05273632
- Testing
- Oxytocin
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia
Spinal Anesthetic Toxicity, Inferior Vena Cava Abnormality
Transthoracic Echocardiography of Inferior Vena Cava Before Spinal Anesthesia Can Predict Hypotension
Study Protocol: Outcome Measurements Primary Outcome The main outcome will be the preoperative performance of the dIVCmax/IVCCI ratio to foresee the incidence of hypotension after spinal anesthesia in a greater extent to that of…
- Conditions
- Spinal Anesthetic Toxicity, Inferior Vena Cava Abnormality, Intraoperative Complications
- Trial name
- NCT03266250
- Testing
- spinal anesthesia
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
High-Risk, Non-Muscle Invasive Bladder Urothelial Carcinoma, Perfusion; Complications
Hyperthermic Intravesical Perfusion for Muscle-invasive Bladder Urothelial Carcinoma
To evaluate the effect of hyperthermic intravesical perfusion on the risk of intraoperative implantation of muscle-invasive bladder urothelial carcinoma and its safety.
- Conditions
- High-Risk, Non-Muscle Invasive Bladder Urothelial Carcinoma, Perfusion; Complications, Intraoperative Complications
- Trial name
- NCT05276167
- Testing
- hyperthermic intravesical perfusion
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Henan Cancer Hospital
Tumor of Pancreas, Surgical Blood Loss
Enucleation of Pancreatic Tumor by Blocking Abdominal Trunk and Superior Mesenteric Artery
Pancreatic enucleation could preserve more healthy pancreatic tissues and functions with a low recurrence risk. However, conventional enucleation can cause significant intraoperative bleeding, especially in which tumors in the…
- Trial name
- NCT06164769
- Testing
- blocking both the abdominal trunk and superior mesenteric artery in the pancreatic enucleation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Zhejiang University
Blood Loss, Surgical, Postoperative Hemorrhage
Efficacy and Safety of Aprotinin on Transfusion Requirements in Patients Undergoing Radical or Total Cystectomy
The purpose of this study is to assess if aprotinin (BAYA0128), given intravenously during your surgery, is safe and can help reduce the need for a blood transfusion during bladder surgery.
- Trial name
- NCT00306150
- Testing
- Trasylol (Aprotinin, BAYA0128)
- Where
- 37 sites in United States, Belgium and 5 more
- Volunteers
- 57 people
- Sponsor
- Bayer
Intraoperative Complications, Respiratory Complication
Lower Inspiratory Oxygen Fraction for Preoxygenation
During the induction period of general anesthesia, surgical patients are inevitably experienced a short period of apnea for endotracheal intubation or other airway manipulation.
- Conditions
- Intraoperative Complications, Respiratory Complication, Oxygen Toxicity, Oxygen Deficiency
- Trial name
- NCT03665259
- Testing
- Pure oxygen group, Lower oxygen group
- Where
- Taiwan
- Volunteers
- 304 people
- Sponsor
- E-DA Hospital
Malignant Hyperthermia
Gene Mutation Spectrum of Malignant Hyperthermia in China
In this study, case information and specimens of patients with malignant hyperthermia(MH) will be collected from all over China, and gene fragment analysis, sanger sequencing method and/or high-throughput whole-genome sequencing…
- Trial name
- NCT04474860
- Testing
- gene sequencing
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Surgical Hemorrhage
A Phase III Study of Hemofence for Hemostasis in Patients With Uncontrolled Exudative Hemorrhage During Spinal Or Orthopedic Surgery
This Phase 3 study was conducted to evaluated the efficacy and safety of Hemofence compared with Floseal Hemostatic Matrix in patients undergoing spinal or orthopedic surgery who required hemostasis for exudative bleeding that…
- Trial name
- NCT07824024
- Testing
- Hemofence, Floseal hemostatic matrix
- Where
- 3 sites in South Korea
- Volunteers
- 172 people
- Sponsor
- BMI Korea
Hypovolemia, Hemorrhage
Trial of 6% HES130/0.4
The study shall evaluate the efficacy and safety of two different hydroxyethyl starch solutions (artificial colloids 6% HES130/0.4 and 6% HES70/0.5, Salinhes®) for intra-operative therapy of hypovolemia and maintenance of…
- Trial name
- NCT01010022
- Testing
- 6% hydroxyethyl starch 130/0.4, 6% hydroxyethyl starch 70/0.5 (Salinhes®)
- Where
- 7 sites in Japan
- Volunteers
- 64 people
- Sponsor
- Fresenius Kabi Japan