Clinical trials: Persistent Pain
Hyperglycemia, Hypercholesterolemia
Glucose Metabolism Disorders and Metabolic Syndrome Before and After Primary Hip and Knee Replacement
Osteoarthritis patients undergoing primary hip and knee replacement are followed-up and changes in their glucose metabolism and other metabolic parameters (obesity, cholesterol levels) are examined.
- Conditions
- Hyperglycemia, Hypercholesterolemia, Persistent Postoperative Pain, Hip Replacement
- Trial name
- HyTe-2 (NCT01743313)
- Where
- Finland
- Volunteers
- 155 people
- Sponsor
- Coxa, Hospital for Joint Replacement
Persistent Pain After Open Inguinal Herniotomy
Variability in Thermal Thresholds in Patients With Persistent Pain After Open Inguinal Herniotomy
The study will investigate the test-retest variability of thermal thresholds in patients with persistent pain after open inguinal herniotomy.
- Trial name
- NCT01768130
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Unilateral Hip Arthroscopy
Painful Post-Operative Hip Study
The goal of this clinical trial is to learn if the hips of people who undergo revision hip arthroscopy look different from the hips of people whose hip pain is resolved with the first hip arthroscopy and of people who choose the…
- Trial name
- NCT07066709
- Testing
- FDG PET/MRI
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Wisconsin, Madison
Chronic Postoperative Pain
Benefit on Chronic Pain of Early Screening and Management of Patients With Persistent Postoperative Pain at 3 Months
Chronic postoperative pain has an overall incidence of approximately 30%, with 5% to 10% of cases classified as severe (numerical rating scale > 6/10).
- Trial name
- DROPS (NCT07160595)
- Testing
- Early management of postoperative pain at 3 months detected using sms
- Where
- 16 sites in France
- Volunteers
- 2,052 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Amputation Stumps, Pain
2PX (Topical Strontium Chloride Hexahydrate) in Patients With Post-Amputation Stump Pain.
The objective of this study is to investigate the analgesic effect of topical strontium chloride in stump pain, and to prospectively determine other efficacy and safety measures of topical strontium chloride in stump pain.
- Trial name
- NCT00592098
- Testing
- Strontium chloride hexahydrate
- Where
- Norway
- Volunteers
- 22 people
- Sponsor
- SantoSolve AS
Chronic Pain, Analgesia
QSPainRelief-STRAT
Investigating the clinical outcomes of drug combinations (opioid + medication acting on the central nervous system) in patients suffering from persistent pain (pain lasting for at least three months) through patient-reported…
- Conditions
- Chronic Pain, Analgesia, Adverse Drug Event, Drug Interaction
- Trial name
- QSPR-STRAT (NCT06244706)
- Testing
- Opioid drug + CNS-acting add-on drug
- Volunteers
- 150 people
- Sponsor
- Université Catholique de Louvain
Persistent Pain After Delivery
Persistent Pain After CS Delivery
Many factors influence the development of persistent pain after CS (chronic pain) as well as post-partum depression. We are attempting to use trajectory pain methods in an attempt to identify those at risk for the development of…
- Trial name
- NCT01996592
- Where
- United States
- Volunteers
- 575 people
- Sponsor
- Wake Forest University Health Sciences
Persistent Postsurgical Pain, Arthritis Hip
Persistent Pain After Hip Replacement
This study is a nationwide cross-sectional survey on pain and satisfaction after total hip arthroplasty (THA). Please find the full protocol uploaded on ClinicalTrials.gov
- Conditions
- Persistent Postsurgical Pain, Arthritis Hip, Neuropathic Pain, Opioid Use
- Trial name
- NCT05845177
- Testing
- Primary Total Hip Arthroplasty
- Where
- Denmark
- Volunteers
- 2,777 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Chronic Pain, Osteo Arthritis Knee
Persistent Pain in Pharmacologically or Surgical Treated Osteoarthritis: Role of Mu-Limpho Marker
The goal of this prospective observational study is to analyze the percentage of expression of B and NK cells expressing Mu opioid receptor on their surface, named Mu-Lympho-Marker (MLM), to measure pain progression in…
- Trial name
- MLM (NCT06637709)
- Where
- Italy
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Breast Cancer, Chronic Post-Procedural Pain
The Effects of Anesthetics on Persistent Pain Following Breast Cancer Surgery
Persistent postoperative pain occurs up to 25 to 60 % after mastectomy. This occurs at a higher frequency than the rate of invasive surgery.Therefore, many ways have been tried to study risk factors.
- Trial name
- NCT03782896
- Testing
- acute postoperative pain
- Where
- South Korea
- Volunteers
- 89 people
- Sponsor
- Samsung Medical Center
Low Back Pain
Characterizing the Role of Pain Sensitivity in Acute to Persistent Low Back Pain
This research study will examine whether enhanced pain sensitivity increases the risk of persistent low back pain. The study will address the highly prevalent and costly condition of persistent low back pain and a major obstacle…
- Trial name
- NCT01981382
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Pain, Dysfunction Sexual
Efficacy of Pain Neuroscience Education in Genito-Pelvic Pain/Penetration Disorder. A Randomized Controlled Trial.
Patients suffering pelvic persistent pain deal with significant pain that affects their quality of life. Often, conservative treatment interventions are scarce for these patients and are therefore not considered.
- Trial name
- NCT05114473
- Testing
- Workshops, Online-accessed material
- Where
- Spain
- Volunteers
- 69 people
- Sponsor
- University of Valencia
Brain Concussion, Neck Pain
Cervical Spine Focused Treatment for Patients With Persistent Concussion Symptoms and Neck Pain
Assess the feasibility of recruiting, enrolling and randomizing patients with concussion symptoms and neck pain to receive manual therapy and cervical rehabilitative exercises in addition to standard concussion treatment.
- Trial name
- ConCerv (NCT06616272)
- Testing
- Cervical rehabilitation, Standard Concussion Care
- Where
- 4 sites in United States, Ireland and 1 more
- Volunteers
- 2 people
- Sponsor
- University of Pittsburgh
Cardiac Disease
Incidence and Risk Factors for Persistent Post-sternotomy Pain After Cardiac Surgery in Local Chinese Population: a Prospective Cohort Study
CPSP is common after cardiac surgery. The reported incidence was 28% to 56% up to 2 years postoperatively. Despite a large number of cross-sectional and retrospective studies, prospective cohort studies examining the incidence of…
- Trial name
- NCT04644666
- Where
- Hong Kong
- Volunteers
- 220 people
- Sponsor
- Chinese University of Hong Kong
Sacroiliac Joint Pain
Peripheral Nerve Stimulation for Treatment of Sacroiliac Joint Pain
Prospective randomized controlled study, primary objective: Pain reduction in patients with chronic Sacroiliac joint pain after therapy either with Peripheral Nerve Stimulation or with best medical treatment.
- Trial name
- SIlencing (NCT05357300)
- Testing
- Peripheral Nerve Stimulation
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- PD Dr. med. Simon Bayerl
Acute Low Back Pain, Chronic Low Back Pain
A Prospective Trial to Identify Biomarkers Involved in the Transition From Acute to Persistent Chronic Low Back Pain
This is a prospective observational cohort multinational clinical study. There are no biomarkers to help predict in which patients acute low back pain (LBP) will transform into chronic low back pain (CLBP).
- Trial name
- NCT02037763
- Where
- 7 sites in United States, Australia and 4 more
- Volunteers
- 5,000 people
- Sponsor
- University of Parma
Fatigue, Pain
Molecular Determinants of Persistent Cancer Related Fatigue
The purpose of this study is to determine if inflammatory markers in blood as well as brain neurotransmitters (markers of in-brain activity and metabolism) are related to long-term or chronic fatigue.
- Conditions
- Fatigue, Pain, Poor Sleep Quality
- Trial name
- MDOF (NCT01980719)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pain
Behavioral Medicine Treatment for Adolescents in Pain
Recurrent pain, such as headache, stomach pain and musculoskeletal pain is common in children and adolescents. Children and adolescents are reported to have restrictions in daily life activities, social contacts, and school…
- Trial name
- NCT01381263
- Testing
- Behavioural medicine treatment, Standard treatment
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Uppsala University
Orthopedic Disorder, Nontraumatic Injury
Web-based Mind-body Program to Improve Resilience Among Risky Substance Users With Persistent Upper Extremity Pain
The investigator aims to conduct a feasibility randomized controlled trial (RCT) (N=50) to test the feasibility, acceptability, and credibility of an asynchronous web-based mind-body intervention (Toolkit for Resilient Life…
- Conditions
- Orthopedic Disorder, Nontraumatic Injury, Upper Extremity Pain, Risky Substance Use
- Trial name
- NCT06991205
- Testing
- Web-TIRELESS, Web-MEUC
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Jafar Bakhshaie
Persistent Post-surgical Pain, Neuropathic Pain
Development of a Personalised Care Plan Designed to Reduce Chronic Post-Operative Pain Following Breast Surgery
Numerous surveys have shown that following breast surgery, longterm pain affects around half of patients. Given that 1 in 9 women will get breast cancer and that surgery is the cornerstone of treatment, persistent pain represents…
- Conditions
- Persistent Post-surgical Pain, Neuropathic Pain, Cancer Pain
- Trial name
- NCT02170415
- Testing
- Protective analgesia, Pain education, Psychological support
- Where
- United Kingdom
- Volunteers
- 154 people
- Sponsor
- Royal Marsden NHS Foundation Trust