Clinical trials: Personality Change
Borderline Personality Disorders, Avoidant Personality Disorders
Changes in the Brain as Borderline Patients Learn to Regulate Their Emotions
Borderline Personality Disorder (BPD), a prevalent psychiatric disorder found in approximately 2% to 6% of the population and 20% of hospitalized psychiatric patients, has proven quite treatment resistant.
- Trial name
- NCT02465697
- Testing
- Reappraisal Training
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Borderline Personality Disorder
User Satisfaction Survey - Personality Disorder Service
Can we improve our community partners satisfaction with a change in how psychiatric consultations are delivered to their clients by our psychiatrist? This survey of users of the service will compare the level of satisfaction…
- Trial name
- NCT00202202
- Testing
- consultation format
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Queen's University
Chronic Respiratory Disease
Effect on Quality of Life of Adapted Information in Pulmonary Rehabilitation in Chronic Respiratory Disease Patients
The purpose of the clinical study is to study the effect of health-related quality of Life of information aimed at reducing the impact of a personality trait (openness to experiences) identified as a risk of non-response to…
- Trial name
- NCT05325086
- Testing
- Adapted information arm, Neutral information arm
- Where
- 2 sites in France
- Volunteers
- 136 people
- Sponsor
- Korian
Obsessive-Compulsive Disorder
ITreatOCD: Predicting the Efficacy of Internet-based Cognitive Behavioral Therapy in Obsessive-compulsive Disorder
In the current study, the investigators will characterize obsessive-compulsive disorder (OCD) patients and healthy controls with a comprehensive clinical and neuroimaging assessment, focusing on the basic psychological processes…
- Trial name
- iTREATOCD (NCT05906069)
- Testing
- ICBT
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pedro Morgado
Mindfulness, Borderline Personality Disorder
Change in Mindfulness in Borderline Personality Disorder
The current study aims to investigate the effect of dialectical behavioral therapy on mindfulness in patients with Borderline Personality Disorder. A treatment group will be compared to a waitlist control group.
- Trial name
- NCT03297840
- Testing
- Dialectical Behavioural Therapy (DBT)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Katharina Bachmann
Depression, Physical Inactivity
Physical Exercise as Adjunctive Therapy for Affective Disorder and Anxiety
"Braining" is a clinical method for physical exercise as adjunctive therapy in psychiatric care. The core components are personnel-led group training sessions and motivating contact with psychiatric staff, as well as measurement…
- Conditions
- Depression, Physical Inactivity, Bipolar Disorder, Anxiety Disorders
- Trial name
- NCT05157386
- Testing
- Braining
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Stockholm
Borderline Personality Disorder
Mechanisms of Change in Brief Treatment for Borderline Personality Disorder
The present two-arm randomized controlled study aims at testing the effects (i.e., symptom reduction) and the underlying mechanisms of change associated with a brief psychiatric treatment (10 sessions over 4 months), compared…
- Trial name
- BPDCHANGE (NCT03717818)
- Testing
- Good Psychiatric Management - Brief, treatment as usual
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Lausanne Hospitals
Personality Disorders
Benchmarking and Change Mechanisms in Personality Disorder Treatment
Personality disorders (PDs) are severe mental disorders characterized by pathological personality traits as well as problems in identity and interpersonal relationships (American Psychiatric Association, 2013).
- Trial name
- NCT06804369
- Testing
- Intensive psychodynamic therapy (PDT)
- Where
- Belgium
- Volunteers
- 91 people
- Sponsor
- KU Leuven
Enduring Personality Change
Effects of High-energy Nutritional Protein-based Bar on the Performance of Young Athletes
A study will be conducted in Lahore. Non probability convenience sampling technique will be applied on patients who will be allocated through computerized randomization into group A \& group B to collect data.
- Trial name
- NCT07065513
- Testing
- Normal diet, Normal diet plus nutritional protein-based bar
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Superior University
Self-harm, Personality Disorder, Borderline
Self-harm Behaviour Among the Most At-risk Adolescents
In the proposed study, three objectives will be pursued: 1. To develop a method to identify more effectively the acute and long-term risk of adolescents with the most threatening self-harm behaviours. 2.
- Conditions
- Self-harm, Personality Disorder, Borderline, Epigenetic Disorder, Non-Suicidal Self Injury
- Trial name
- SH-MARA (NCT05765864)
- Testing
- Enrollment questionnaire, General questionnaire1, General questionnaire2, General questionnaire3, Columbia Suicide Severity Rating Scale (CSSRS), The Brief Non-Suicidal Self-Injury Assessment Tool (B-NSSI-AT)
- Where
- 2 sites in Slovenia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana, Faculty of Medicine
Borderline Personality Disorder
Methylation Status of BDNF Gene After Dialectical Behavior Therapy in BPD
Borderline personality disorder (BPD) is a chronic and debilitating syndrome associated with considerable morbidity, mortality, and high rates of medical and psychiatric utilization services.
- Trial name
- NCT02134223
- Testing
- Dialectical behavior therapy, Treatment as Usual: any other drug or psychotherapy offered to participants, except DBT
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Borderline Personality Disorder
Evaluation of a Modified Dialectical Behavior Therapy Program
The goal of this pilot project is to offer outpatient Dialectical Behavior Therapy (DBT) treatment as described in Linehan's text (1993), which is considered an effective treatment of borderline personality disorder.
- Trial name
- NCT01635556
- Testing
- Dialectical Behavior therapy
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Manitoba
Borderline Personality Disorder, Suicide
Comparing Treatments for Self-Injury and Suicidal Behavior in People With Borderline Personality Disorder
This study will compare the effectiveness of two treatments, dialectical behavior therapy versus fluoxetine with clinical management, for reducing the risk of self-injury and suicidal behavior in people with borderline…
- Trial name
- NCT00834834
- Testing
- Fluoxetine, DBT, Citalopram
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- New York State Psychiatric Institute
Attention Deficit Disorder With Hyperactivity, Mental Disorders Diagnosed in Childhood
Brain Changes in Children and Adolescents With Behavioral Problems
Purpose: This study will examine brain activity in children age 10-18 with disruptive behavior problems, including conduct disorder (CD), oppositional defiant disorder (ODD), and attention deficit hyperactivity disorder (ADHD)…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Mental Disorders Diagnosed in Childhood, Conduct Disorder
- Trial name
- NCT00104039
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Obsessive - Compulsive Disorder
Feasibility and Efficacy Trial of a Culturally Adapted Guided Self-Help CBT Manual for OCD
This randomised controlled trial (RCT) aims to assess the feasibility, acceptability, and preliminary efficacy of a culturally adapted, guided self-help cognitive behaviour therapy (CBT) manual specifically designed for…
- Trial name
- NCT07239401
- Testing
- Culturally adapted Guided Self-Help OCD Manual
- Volunteers
- 108 people
- Sponsor
- Pakistan Association of Cognitive Therapists
Borderline Personality Disorder
Personality Change Study for Borderline Personality Disorder
Participants with borderline personality disorder will undergo an a 2 - 4 week baseline assessment to determine level of outcomes of interest in the absence of treatment.
- Trial name
- NCT06005129
- Testing
- Personality-Based Therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Dementia of Alzheimer Type, Dementia Frontotemporal
Multifactorial Approach to Dementia, Multicentric Study
The goal of this observational study is to assess the role of narcisistic personality disorder and life stressful events in conversion rate to dementia, using a three tier approach along three research lines employing subjects…
- Conditions
- Dementia of Alzheimer Type, Dementia Frontotemporal, Narcissistic Personality Disorder, Depression
- Trial name
- NCT05923307
- Where
- Argentina
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Daniel Serrani Azcurra
Pain, Individual Difference
Identifying Neuroimaging Biomarkers, Demographic, Personality and Sensory Factors for Predicting Extreme Pain Responses to Various Experimental Pain Stimulations in Healthy Subjects
The proneness to react to noxious stimuli varies widely between individuals and pain ratings of seemingly identical noxious stimuli may range from "no pain" to "excruciating pain" .
- Trial name
- NCT03436264
- Testing
- MRI
- Where
- Israel
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Health Behavior, Quality of Life
The Lake Nona Life Project
The Lake Nona Life Project aims to examine the health and wellness of participants over the course of multiple years, focusing on the links between health and wellness, longevity, quality of life, and human performance.
- Conditions
- Health Behavior, Quality of Life, Aging
- Trial name
- NCT02533804
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Learning Development, Obstetric
Adaptive Gamification in Obstetric Nursing
This pilot study, conducted at the University of Atlántico Medio, seeks to transform the training of future nurses through a "Precision Education" model, moving away from generic simulations to focus on learning adapted to the…
- Trial name
- NCT07434336
- Testing
- Adapted Gamified, Generic Gamified
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Servicio Canario de Salud