Clinical trials: Personality Disorder, Borderline
Borderline Personality Disorder (BPD)
Social Integration During Psychiatric Inpatient Therapy as Predictor of Treatment Response
The present longitudinal study aims at (i) identifying neurobiological mechanisms associated with successful social integration during the treatment of inpatients with Borderline Personality Disorder (BPD) and (ii) improving…
- Trial name
- SANITY (NCT04770038)
- Testing
- Dialectical Behavior Therapy (DBT)
- Where
- Germany
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Oldenburg
Borderline Personality Disorder
A Novel Drug for Borderline Personality Disorder
Borderline Personality Disorder (BPD) is one of the most prevalent psychiatric disorders with high morbidity and mortality. It affects the lives of millions worldwide and is often highly incapacitating, leading to significant…
- Trial name
- NCT02097706
- Testing
- NMDA receptor antagonist (active drug), Lactose packed capsule (inert/inactive arm)
- Where
- Australia
- Volunteers
- 150 people
- Sponsor
- The Alfred
Effects of Oxytocin on Borderline Personality Disorder, Borderline Personality Disorder
"The Effects of Oxytocin on Patients With Borderline Personality Disorder"
RCT. Two substudies (clinical and experimental). Main objective of the trial is to examine if oxytocin, compared to placebo shows any additional effect on the therapy achievements (outcome) of patients with borderline personality…
- Trial name
- NCT01243658
- Testing
- Oxytocin
- Where
- Germany
- Volunteers
- 138 people
- Sponsor
- Prof. Dr. Markus Heinrichs
Borderline Personality Disorder
Guanfacine to Treat Borderline Personality Disorder
This study is designed to investigate whether guanfacine (Tenex) is an effective treatment for borderline personality disorder (BPD), an illness often characterized by unstable mood and impulsive aggression.
- Trial name
- NCT00358969
- Testing
- guanfacine (Tenex)
- Where
- United States
- Sponsor
- Icahn School of Medicine at Mount Sinai
Borderline Personality Disorder, Eating Disorders
Chrysalis Day Program Body Mass Index Study
This is a study to determine if the approach taken to treat patients in the Chrysalis Day Hospital Program will favourably effect their health status as assessed by Body Mass Index (BMI)
- Trial name
- NCT00202215
- Testing
- Chrysalis Day Program
- Where
- Canada
- Volunteers
- 106 people
- Sponsor
- Queen's University
Borderline Personality Disorder, Social Rejection
Exploration of Theory of Mind in a Situation of Social Rejection in Borderline Personality Disorder
Theory of mind is one of the features of mentalization. It can be defined as the ability to predict or explain other's behavior with the assignment of beliefs, wishes, and intentions and knowing how to discriminate them with our…
- Conditions
- Borderline Personality Disorder, Social Rejection, Social Skills, Cognitive Function 1, Social
- Trial name
- LIMITOM (NCT03968081)
- Testing
- Cyberball
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Versailles Hospital
Personality Disorder, Borderline, Personality Trait
Bridging Affect Consciousness, Mentalization and Trauma- Exploring an Integrative Treatment Approach for Personality Disorder (PD).
Study background: Specialized Group Outpatient Clinic within specialist mental health services, tailoring two year group treatment programmes for severe Avoidant PD (AvPD) and Borderline PD (BPD) with Affect Consciousness (AC)…
- Conditions
- Personality Disorder, Borderline, Personality Trait, Personality Disorder, Personality Type
- Trial name
- NCT06983002
- Testing
- Experimental group: AC-group therapy intervention., Control group 1: Body Awareness Group., Control group 2: Art Psychotherapy group.
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Helse Stavanger HF
Borderline Personality Disorder
Stress & Social Cognition in BPD (part 2)
The investigators will examine how a combination of pharmacological mineralocorticoid receptor (MR) stimulation and psychosocial stress will influence prosocial behavior in patients with Borderline Personality Disorder (BPD)…
- Trial name
- SOKO-2 (NCT05310253)
- Testing
- Fludrocortisone, Trier Social Stress Test (TSST)
- Where
- Germany
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Borderline Personality Disorder
An 18-Month Psychotherapy of Borderline Personality Disorder
The purpose of the study is to examine the impact of an 18-month psychotherapy treatment for borderline personality disorder. The investigators will examine changes in psychosocial and work functioning in patients with borderline…
- Trial name
- NCT03329677
- Testing
- Transference-focused Psychotherapy (TFP)
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Weill Medical College of Cornell University
Borderline Personality Disorder
Mentalization-based Treatment Versus Bona-fide Treatment for Patients With Borderline Personality Disorder in Germany
Background: Borderline Personality Disorder (BPD) is a serious mental disorder. Mentalization-based treatment (MBT) is one evidence-based treatment for individuals with BPD.
- Trial name
- MAGNET (NCT06018272)
- Testing
- Mentalization-Based Treatment (MBT), Bona-Fide Treatment in Germany (BFT)
- Where
- 5 sites in Germany
- Volunteers
- 304 people
- Sponsor
- Heidelberg University
Borderline Personality Disorder (BPD)
The Role of Gender in Borderline Personality Disorder
This study is a mixed-methods, single-arm cross-sectional study comprising 1) a qualitative, exploratory, critical-constructivist content analysis examining the significance of gender in relationship experiences and…
- Trial name
- BPD-G (NCT07639957)
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- University Hospital Heidelberg
Borderline Personality Disorder
Neurofeedback for Borderline Personality Disorder
The goal of this study is to evaluate whether rtfMRI-nf training to increase the amygdala response to positive memories may serve as an intervention for borderline personality disorder.
- Trial name
- NCT05398627
- Testing
- Amygdala Neurofeedback
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kymberly Young
Borderline Personality Disorder
Intensified, Inpatient Adaptation of Dialectical Behavior Therapy (DBT)
An randomized clinical trial to investigate whether among adult borderline patients (18 - 40 year), intensified inpatient short term (12 weeks) inpatient Dialectical Behavior Therapy (DBT) is more effective in declining the…
- Trial name
- REDBT (NCT01904227)
- Testing
- standard outpatient DBT, Inpatient Adaptation of DBT
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- GGZ Rivierduinen
Borderline Personality Disorder
MBT-early: a Single Case Experimental Design
Borderline personality disorder (BPD) is characterized by problems in emotion regulation, identity disturbances, and impaired interpersonal functioning.
- Trial name
- NCT06212024
- Testing
- Mentalization Based Treatment-early
- Where
- Netherlands
- Volunteers
- 8 people
- Sponsor
- De Viersprong
Borderline Personality Disorder (BPD)
Combining Transcranial Magnetic Stimulation With Emotion Regulation Skills Training in Borderline Personality Disorder
Impaired emotion regulation is a core feature of borderline personality disorder (BPD) and a known driver of functional impairment, interpersonal difficulties, self-harm, and suicidality.
- Trial name
- NCT07714005
- Testing
- Transcranial Magnetic Stimulation (TMS), Emotion Regulation Skills Training
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Massachusetts General Hospital
Borderline Personality Disorder
Five Factor Model Treatment for Borderline Personality Disorder
The primary purpose of this study is to explore acceptability, feasibility, and preliminary efficacy of a novel cognitive-behavioral treatment for borderline personality disorder (BPD).
- Trial name
- NCT04587518
- Testing
- Personality-Based Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Borderline Symptoms, Borderline Personality Disorder
The Effectiveness of Group Schema Therapy in the Treatment of Borderline Symptoms in Adolescents
The goal of this randomized and controlled trial is to assess the effectiveness of group schema therapy in the treatment of adolescents with borderline symptoms.
- Trial name
- NCT06606002
- Testing
- Group schema therapy, Treatment as Usual (TAU)
- Where
- Finland
- Volunteers
- 64 people
- Sponsor
- Turku University Hospital
Borderline Personality Disorder
20 Weeks DBT Group Skills Training Study
The aim of this study is to evaluate the effectiveness of a 20-week Dialectical Behaviour Therapy (DBT) skills training group for the treatment of chronic suicidal and non-suicidal self-injurious (NSSI) behaviours in individuals…
- Trial name
- NCT01193205
- Testing
- Skills Training
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Centre for Addiction and Mental Health
Borderline Personality Disorder, Major Depression
Event Related Potentials in Borderline Personality Disorder and Major Depression
This study examines whether depression in people with borderline personality disorder is different than depression in people without borderline personality disorder. Unlike people who have depression alone (i.e.
- Trial name
- NCT01469663
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Neuropsychology
Cognitive Rehabilitation Versus Psychoeducation in Psychosocial Functioning of Borderline Personality Disorder
Study design was a multicenter, randomized, rater-blind clinical trial. There were two-parallel arms (1:1) to evaluate functional, clinical and cognitive efficacy of a specific cognitive rehabilitation group intervention (CR)…
- Trial name
- NCT02033044
- Testing
- cognitive remediation, Psychoeducation
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Hospital San Carlos, Madrid